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Items: 1 to 50 of 78

1.

Results of a survey of cancer patients' willingness to travel to participate in a clinical trial.

Zdenkowski N, Lynam J, Sproule V, Wall L, Searston J, Brown S.

Intern Med J. 2019 Oct;49(10):1321-1325. doi: 10.1111/imj.14456.

PMID:
31602764
2.

A biotin-conjugated photo-activated CO-releasing molecule (biotinCORM): efficient CO-release from an avidin-biotinCORM protein adduct.

Ward JS, De Palo A, Aucott BJ, Moir JWB, Lynam JM, Fairlamb IJS.

Dalton Trans. 2019 Oct 10. doi: 10.1039/c9dt03429c. [Epub ahead of print]

PMID:
31598614
3.

TROG 18.01 phase III randomised clinical trial of the Novel Integration of New prostate radiation schedules with adJuvant Androgen deprivation: NINJA study protocol.

Martin J, Keall P, Siva S, Greer P, Christie D, Moore K, Dowling J, Pryor D, Chong P, McLeod N, Raman A, Lynam J, Smart J, Oldmeadow C, Tang CI, Murphy DG, Millar J, Tai KH, Holloway L, Reeves P, Hayden A, Lim T, Holt T, Sidhom M.

BMJ Open. 2019 Aug 20;9(8):e030731. doi: 10.1136/bmjopen-2019-030731.

4.

Internal Nucleophilic Catalyst Mediated Cyclisation/Ring Expansion Cascades for the Synthesis of Medium-Sized Lactones and Lactams.

Lawer A, Rossi-Ashton JA, Stephens TC, Challis BJ, Epton RG, Lynam JM, Unsworth WP.

Angew Chem Int Ed Engl. 2019 Sep 23;58(39):13942-13947. doi: 10.1002/anie.201907206. Epub 2019 Aug 13. Review.

PMID:
31340086
5.

Delineating the critical role of acid additives in Mn-catalysed C-H bond functionalisation processes.

Hammarback LA, Robinson A, Lynam JM, Fairlamb IJS.

Chem Commun (Camb). 2019 Mar 12;55(22):3211-3214. doi: 10.1039/c9cc00257j.

PMID:
30806417
6.

Mechanistic Insight into Catalytic Redox-Neutral C-H Bond Activation Involving Manganese(I) Carbonyls: Catalyst Activation, Turnover, and Deactivation Pathways Reveal an Intricate Network of Steps.

Hammarback LA, Robinson A, Lynam JM, Fairlamb IJS.

J Am Chem Soc. 2019 Feb 13;141(6):2316-2328. doi: 10.1021/jacs.8b09095. Epub 2019 Jan 30.

PMID:
30698423
7.

It takes a village: a realist synthesis of social pediatrics program.

Tyler I, Lynam J, O'Campo P, Manson H, Lynch M, Dashti B, Turner N, Feller A, Ford-Jones EL, Makin S, Loock C.

Int J Public Health. 2019 Jun;64(5):691-701. doi: 10.1007/s00038-018-1190-7. Epub 2018 Dec 24. Review.

8.

Synthesis, Mesomorphism, and Photophysics of 2,5-Bis(dodecyloxyphenyl)pyridine Complexes of Platinum(IV).

Parker RR, Sarju JP, Whitwood AC, Williams JAG, Lynam JM, Bruce DW.

Chemistry. 2018 Dec 17;24(71):19010-19023. doi: 10.1002/chem.201804026. Epub 2018 Nov 15.

PMID:
30211455
9.

Clinical correlates of severe thrombocytopenia from temozolomide in glioblastoma patients.

Arulananda S, Lynam J, Sem Liew M, Wada M, Cher L, Gan HK.

Intern Med J. 2018 Oct;48(10):1206-1214. doi: 10.1111/imj.14000.

PMID:
29923272
10.

Small bite-angle 2-phosphinophosphinine ligands enable rhodium-catalysed hydroboration of carbonyls.

Newland RJ, Lynam JM, Mansell SM.

Chem Commun (Camb). 2018 May 24;54(43):5482-5485. doi: 10.1039/c8cc01880d.

PMID:
29756624
11.

Hydrothermal Liquefaction of Loblolly Pine: Effects of Various Wastes on Produced Biocrude.

Saba A, Lopez B, Lynam JG, Reza MT.

ACS Omega. 2018 Mar 14;3(3):3051-3059. doi: 10.1021/acsomega.8b00045. eCollection 2018 Mar 31.

12.

The Antimicrobial Activity of a Carbon Monoxide Releasing Molecule (EBOR-CORM-1) Is Shaped by Intraspecific Variation within Pseudomonas aeruginosa Populations.

Flanagan L, Steen RR, Saxby K, Klatter M, Aucott BJ, Winstanley C, Fairlamb IJS, Lynam JM, Parkin A, Friman VP.

Front Microbiol. 2018 Feb 8;9:195. doi: 10.3389/fmicb.2018.00195. eCollection 2018.

13.

Utility of selection methods for specialist medical training: A BEME (best evidence medical education) systematic review: BEME guide no. 45.

Roberts C, Khanna P, Rigby L, Bartle E, Llewellyn A, Gustavs J, Newton L, Newcombe JP, Davies M, Thistlethwaite J, Lynam J.

Med Teach. 2018 Jan;40(1):3-19. doi: 10.1080/0142159X.2017.1367375. Epub 2017 Aug 28. Review.

PMID:
28847200
14.

A Structurally Characterized Fluoroalkyne.

Hall LM, Tew DP, Pridmore NE, Whitwood AC, Lynam JM, Slattery JM.

Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7551-7556. doi: 10.1002/anie.201702401. Epub 2017 May 23.

PMID:
28544216
15.

Deep eutectic solvents' ability to solubilize lignin, cellulose, and hemicellulose; thermal stability; and density.

Lynam JG, Kumar N, Wong MJ.

Bioresour Technol. 2017 Aug;238:684-689. doi: 10.1016/j.biortech.2017.04.079. Epub 2017 Apr 22.

PMID:
28494411
16.

Redox-Tagged Carbon Monoxide-Releasing Molecules (CORMs): Ferrocene-Containing [Mn(C^N)(CO)4] Complexes as a Promising New CORM Class.

Aucott BJ, Ward JS, Andrew SG, Milani J, Whitwood AC, Lynam JM, Parkin A, Fairlamb IJS.

Inorg Chem. 2017 May 1;56(9):5431-5440. doi: 10.1021/acs.inorgchem.7b00509. Epub 2017 Apr 19.

PMID:
28422490
17.

Redox Couple Involving NOx in Aerobic Pd-Catalyzed Oxidation of sp3-C-H Bonds: Direct Evidence for Pd-NO3-/NO2- Interactions Involved in Oxidation and Reductive Elimination.

Wenzel MN, Owens PK, Bray JT, Lynam JM, Aguiar PM, Reed C, Lee JD, Hamilton JF, Whitwood AC, Fairlamb IJ.

J Am Chem Soc. 2017 Jan 25;139(3):1177-1190. doi: 10.1021/jacs.6b10853. Epub 2017 Jan 11.

PMID:
28075565
18.

Toxicity of tryptophan manganese(i) carbonyl (Trypto-CORM), against Neisseria gonorrhoeae.

Ward JS, Morgan R, Lynam JM, Fairlamb IJS, Moir JWB.

Medchemcomm. 2016 Dec 6;8(2):346-352. doi: 10.1039/c6md00603e. eCollection 2017 Feb 1.

19.

Manganese(I)-Catalyzed C-H Activation: The Key Role of a 7-Membered Manganacycle in H-Transfer and Reductive Elimination.

Yahaya NP, Appleby KM, Teh M, Wagner C, Troschke E, Bray JT, Duckett SB, Hammarback LA, Ward JS, Milani J, Pridmore NE, Whitwood AC, Lynam JM, Fairlamb IJ.

Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12455-9. doi: 10.1002/anie.201606236. Epub 2016 Sep 7.

20.

Gold-alkynyls in catalysis: alkyne activation, gold cumulenes and nuclearity.

Halliday CJ, Lynam JM.

Dalton Trans. 2016 Aug 9;45(32):12611-26. doi: 10.1039/c6dt01641c.

PMID:
27415145
21.

Access to novel fluorovinylidene ligands via exploitation of outer-sphere electrophilic fluorination: new insights into C-F bond formation and activation.

Milner LM, Hall LM, Pridmore NE, Skeats MK, Whitwood AC, Lynam JM, Slattery JM.

Dalton Trans. 2016 Jan 28;45(4):1717-26. doi: 10.1039/c5dt04596g.

PMID:
26701305
22.

Reactions of alkynes with cis-RuCl2(dppm)2: exploring the interplay of vinylidene, alkynyl and η(3)-butenynyl complexes.

Eaves SG, Yufit DS, Skelton BW, Lynam JM, Low PJ.

Dalton Trans. 2015 Dec 28;44(48):21016-24. doi: 10.1039/c5dt03844h. Epub 2015 Nov 20.

23.

Total Synthesis and Stereochemical Revision of Phacelocarpus 2-Pyrone A.

Ronson TO, Burns MJ, Voelkel MH, Evans KJ, Lynam JM, Taylor RJ, Fairlamb IJ.

Chemistry. 2015 Dec 21;21(52):18905-9. doi: 10.1002/chem.201504089. Epub 2015 Nov 16.

PMID:
26568186
24.

Outer-Sphere Electrophilic Fluorination of Organometallic Complexes.

Milner LM, Pridmore NE, Whitwood AC, Lynam JM, Slattery JM.

J Am Chem Soc. 2015 Aug 26;137(33):10753-9. doi: 10.1021/jacs.5b06547. Epub 2015 Aug 13.

25.

Synthesis of a series of new platinum organometallic complexes derived from bidentate Schiff-base ligands and their catalytic activity in the hydrosilylation and dehydrosilylation of styrene.

Lachachi MB, Benabdallah T, Aguiar PM, Youcef MH, Whitwood AC, Lynam JM.

Dalton Trans. 2015 Jul 14;44(26):11919-28. doi: 10.1039/c5dt01407g. Epub 2015 Jun 10.

PMID:
26061657
26.

Dispersion, solvent and metal effects in the binding of gold cations to alkynyl ligands: implications for Au(I) catalysis.

Ciano L, Fey N, Halliday CJ, Lynam JM, Milner LM, Mistry N, Pridmore NE, Townsend NS, Whitwood AC.

Chem Commun (Camb). 2015 Jun 14;51(47):9702-5. doi: 10.1039/c5cc02629f.

27.

Rapid Markovnikov addition of HCl to a pendant alkyne: evidence for a quinoidal cumulene.

Eaves SG, Hart SJ, Whitwood AC, Yufit DS, Low PJ, Lynam JM.

Chem Commun (Camb). 2015 Jun 7;51(45):9362-5. doi: 10.1039/c4cc09696g.

PMID:
25961079
28.

Confocal and fluorescence lifetime imaging sheds light on the fate of a pyrene-tagged carbon monoxide-releasing Fischer carbene chromium complex.

Arrowsmith RL, Atkin AJ, Botchway SW, Fairlamb IJ, Lynam JM, Moir JW, Pascu SI, Ward JS, Zhang WQ.

Dalton Trans. 2015 Mar 21;44(11):4957-62. doi: 10.1039/c4dt03312d.

PMID:
25553721
29.

Evidence for a SN2-type pathway in the exchange of phosphines at a [PhSe]+ centre.

Forfar LC, Green M, Haddow MF, Hussein S, Lynam JM, Slattery JM, Russell CA.

Dalton Trans. 2015 Jan 7;44(1):110-8. doi: 10.1039/c4dt02253j.

PMID:
25318556
30.

Visible-light-induced CO release from a therapeutically viable tryptophan-derived manganese(I) carbonyl (TryptoCORM) exhibiting potent inhibition against E. coli.

Ward JS, Lynam JM, Moir J, Fairlamb IJ.

Chemistry. 2014 Nov 10;20(46):15061-8. doi: 10.1002/chem.201403305. Epub 2014 Oct 3.

PMID:
25279824
31.

Glycerol as an ionic liquid co-solvent for pretreatment of rice hulls to enhance glucose and xylose yield.

Lynam JG, Coronella CJ.

Bioresour Technol. 2014 Aug;166:471-8. doi: 10.1016/j.biortech.2014.05.086. Epub 2014 May 29.

PMID:
24950092
32.

Mechanistic insight into the ruthenium-catalysed anti-Markovnikov hydration of alkynes using a self-assembled complex: a crucial role for ligand-assisted proton shuttle processes.

Breit B, Gellrich U, Li T, Lynam JM, Milner LM, Pridmore NE, Slattery JM, Whitwood AC.

Dalton Trans. 2014 Aug 7;43(29):11277-85. doi: 10.1039/c4dt00712c. Epub 2014 May 15.

PMID:
24828970
33.

[Ru(η5-C5H5)(η6-C10H8)]PF6 as a catalyst precursor for the one-pot direct C-H alkenylation of nitrogen heterocycles.

Lynam JM, Milner LM, Mistry NS, Slattery JM, Warrington SR, Whitwood AC.

Dalton Trans. 2014 Mar 21;43(11):4565-72. doi: 10.1039/c3dt52984c.

PMID:
24481140
34.

The elusive structure of Pd2(dba)3. Examination by isotopic labeling, NMR spectroscopy, and X-ray diffraction analysis: synthesis and characterization of Pd2(dba-Z)3 complexes.

Kapdi AR, Whitwood AC, Williamson DC, Lynam JM, Burns MJ, Williams TJ, Reay AJ, Holmes J, Fairlamb IJ.

J Am Chem Soc. 2013 Jun 5;135(22):8388-99. doi: 10.1021/ja403259c. Epub 2013 May 23.

PMID:
23701049
35.

Reaction kinetics of hydrothermal carbonization of loblolly pine.

Reza MT, Yan W, Uddin MH, Lynam JG, Hoekman SK, Coronella CJ, Vásquez VR.

Bioresour Technol. 2013 Jul;139:161-9. doi: 10.1016/j.biortech.2013.04.028. Epub 2013 Apr 15.

PMID:
23651600
36.

cis-1,3,5-Triaminocyclohexane as a facially capping ligand for ruthenium(II).

Gamble AJ, Lynam JM, Thatcher RJ, Walton PH, Whitwood AC.

Inorg Chem. 2013 Apr 15;52(8):4517-27. doi: 10.1021/ic302819j. Epub 2013 Mar 22.

PMID:
23517123
37.

Ruthenium-mediated C-H functionalization of pyridine: the role of vinylidene and pyridylidene ligands.

Johnson DG, Lynam JM, Mistry NS, Slattery JM, Thatcher RJ, Whitwood AC.

J Am Chem Soc. 2013 Feb 13;135(6):2222-34. doi: 10.1021/ja3097256. Epub 2013 Jan 31.

PMID:
23244051
38.

Detection of unusual reaction intermediates during the conversion of W(N2)2(dppe)2 to W(H)4(dppe)2 and of H2O into H2.

Eguillor B, Caldwell PJ, Cockett MC, Duckett SB, John RO, Lynam JM, Sleigh CJ, Wilson I.

J Am Chem Soc. 2012 Nov 7;134(44):18257-65. doi: 10.1021/ja302202q. Epub 2012 Oct 26.

PMID:
23072491
39.

A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM).

Ward JS, Lynam JM, Moir JW, Sanin DE, Mountford AP, Fairlamb IJ.

Dalton Trans. 2012 Sep 21;41(35):10514-7. doi: 10.1039/c2dt31588b. Epub 2012 Jul 31.

PMID:
22850731
40.

Reformulated tenofovir gel for use as a dual compartment microbicide.

Dezzutti CS, Rohan LC, Wang L, Uranker K, Shetler C, Cost M, Lynam JD, Friend D.

J Antimicrob Chemother. 2012 Sep;67(9):2139-42. doi: 10.1093/jac/dks173. Epub 2012 May 11.

41.

Pretreatment of rice hulls by ionic liquid dissolution.

Lynam JG, Reza MT, Vasquez VR, Coronella CJ.

Bioresour Technol. 2012 Jun;114:629-36. doi: 10.1016/j.biortech.2012.03.004. Epub 2012 Mar 9.

PMID:
22446050
42.

Regiochemistry in cobalt-mediated intermolecular Pauson-Khand reactions of unsymmetrical internal heteroaromatic alkynes with norbornene.

Moulton BE, Whitwood AC, Duhme-Klair AK, Lynam JM, Fairlamb IJ.

J Org Chem. 2011 Jul 1;76(13):5320-34. doi: 10.1021/jo200664m. Epub 2011 Jun 2.

PMID:
21591814
43.

Modification of the deoxy-myoglobin/carbonmonoxy-myoglobin UV-vis assay for reliable determination of CO-release rates from organometallic carbonyl complexes.

Atkin AJ, Lynam JM, Moulton BE, Sawle P, Motterlini R, Boyle NM, Pryce MT, Fairlamb IJ.

Dalton Trans. 2011 Jun 7;40(21):5755-61. doi: 10.1039/c0dt01809k. Epub 2011 Apr 27.

PMID:
21523300
44.

Acetic acid and lithium chloride effects on hydrothermal carbonization of lignocellulosic biomass.

Lynam JG, Coronella CJ, Yan W, Reza MT, Vasquez VR.

Bioresour Technol. 2011 May;102(10):6192-9. doi: 10.1016/j.biortech.2011.02.035. Epub 2011 Feb 13.

PMID:
21411315
45.

Insights into the intramolecular acetate-mediated formation of ruthenium vinylidene complexes: a ligand-assisted proton shuttle (LAPS) mechanism.

Johnson DG, Lynam JM, Slattery JM, Welby CE.

Dalton Trans. 2010 Nov 21;39(43):10432-41. doi: 10.1039/c0dt00431f. Epub 2010 Oct 12.

PMID:
20938549
46.

Atropisomerisation in sterically hindered α,β-disubstituted cyclopentenones derived from an intermolecular cobalt(0)-mediated Pauson-Khand reaction.

Moulton BE, Lynam JM, Duhme-Klair AK, Zheng W, Lin Z, Fairlamb IJ.

Org Biomol Chem. 2010 Dec 7;8(23):5398-403. doi: 10.1039/c0ob00264j. Epub 2010 Sep 29.

PMID:
20877916
47.

Group 6 carbon monoxide-releasing metal complexes with biologically-compatible leaving groups.

Zhang WQ, Whitwood AC, Fairlamb IJ, Lynam JM.

Inorg Chem. 2010 Oct 4;49(19):8941-52. doi: 10.1021/ic101230j.

PMID:
20809626
48.

Recent mechanistic and synthetic developments in the chemistry of transition-metal vinylidene complexes.

Lynam JM.

Chemistry. 2010 Jul 26;16(28):8238-47. doi: 10.1002/chem.201000695.

PMID:
20607768
49.

In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide.

Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, Cost M, Huang Y, Gai F, Billitto N, Lynam JD, Pryke K, Graebing P, Hopkins N, Rooney JF, Friend D, Dezzutti CS.

PLoS One. 2010 Feb 19;5(2):e9310. doi: 10.1371/journal.pone.0009310.

50.

Smart investments in sustainable food production: revisiting mixed crop-livestock systems.

Herrero M, Thornton PK, Notenbaert AM, Wood S, Msangi S, Freeman HA, Bossio D, Dixon J, Peters M, van de Steeg J, Lynam J, Parthasarathy Rao P, Macmillan S, Gerard B, McDermott J, Seré C, Rosegrant M.

Science. 2010 Feb 12;327(5967):822-5. doi: 10.1126/science.1183725.

PMID:
20150490

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