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Items: 1 to 50 of 104

1.

Cloning of human thymic stromal lymphopoietin (TSLP) and signaling mechanisms leading to proliferation.

Quentmeier H, Drexler HG, Fleckenstein D, Zaborski M, Armstrong A, Sims JE, Lyman SD.

Leukemia. 2001 Aug;15(8):1286-92.

2.

Chronic overexpression of membrane-bound flt3 ligand by T lymphocytes in severe aplastic anaemia.

Pfister O, Chklovskaia E, Jansen W, Mészáros K, Nissen C, Rahner C, Hurwitz N, Bogatcheva N, Lyman SD, Wodnar-Filipowicz A.

Br J Haematol. 2000 Apr;109(1):211-20.

PMID:
10848802
3.

Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.

McKenna HJ, Stocking KL, Miller RE, Brasel K, De Smedt T, Maraskovsky E, Maliszewski CR, Lynch DH, Smith J, Pulendran B, Roux ER, Teepe M, Lyman SD, Peschon JJ.

Blood. 2000 Jun 1;95(11):3489-97.

PMID:
10828034
4.

Identification of CD7 as a cognate of the human K12 (SECTM1) protein.

Lyman SD, Escobar S, Rousseau AM, Armstrong A, Fanslow WC.

J Biol Chem. 2000 Feb 4;275(5):3431-7.

5.

Modulation of haematopoietic progenitor development by FLT-3 ligand.

Banu N, Deng B, Lyman SD, Avraham H.

Cytokine. 1999 Sep;11(9):679-88.

PMID:
10479404
6.

Endogenous FLT-3 ligand serum levels are associated with disease stage in patients with myelodysplastic syndromes.

Zwierzina H, Anderson JE, Rollinger-Holzinger I, Torok-Storb B, Nuessler V, Lyman SD.

Leukemia. 1999 Apr;13(4):553-7.

7.

Mechanism of flt3 ligand expression in bone marrow failure: translocation from intracellular stores to the surface of T lymphocytes after chemotherapy-induced suppression of hematopoiesis.

Chklovskaia E, Jansen W, Nissen C, Lyman SD, Rahner C, Landmann L, Wodnar-Filipowicz A.

Blood. 1999 Apr 15;93(8):2595-604.

PMID:
10194439
8.

Synergy of growth factors during mobilization of peripheral blood precursor cells with recombinant human Flt3-ligand and granulocyte colony-stimulating factor in rabbits.

Pless M, Wodnar-Filipowicz A, John L, Baldomero H, Lyman SD, Nissen C, Gratwohl A.

Exp Hematol. 1999 Jan;27(1):155-61.

PMID:
9923454
9.

Leukemic predisposition of mice transplanted with gene-modified hematopoietic precursors expressing flt3 ligand.

Hawley TS, Fong AZ, Griesser H, Lyman SD, Hawley RG.

Blood. 1998 Sep 15;92(6):2003-11.

PMID:
9731058
10.

FLT-3 ligand provides hematopoietic protection from total body irradiation in rabbits.

Gratwohl A, John L, Baldomero H, Roth J, Tichelli A, Nissen C, Lyman SD, Wodnar-Filipowicz A.

Blood. 1998 Aug 1;92(3):765-9.

PMID:
9680342
11.

Biologic effects and potential clinical applications of Flt3 ligand.

Lyman SD.

Curr Opin Hematol. 1998 May;5(3):192-6. Review.

PMID:
9664159
12.

Haematopoietic action of flt3 ligand on cord blood-derived CD34-positive cells expressing different levels of flt3 or c-kit tyrosine kinase receptor: comparison with stem cell factor.

Sakabe H, Kimura T, Zeng Z, Minamiguchi H, Tsuda S, Yokota S, Hodohara K, Abe T, Lyman SD, Sonoda Y.

Eur J Haematol. 1998 May;60(5):297-306.

PMID:
9654159
13.

Structure-function analysis of FLT3 ligand-FLT3 receptor interactions using a rapid functional screen.

Graddis TJ, Brasel K, Friend D, Srinivasan S, Wee S, Lyman SD, March CJ, McGrew JT.

J Biol Chem. 1998 Jul 10;273(28):17626-33.

14.
15.

The Epstein-Barr virus BARF1 gene encodes a novel, soluble colony-stimulating factor-1 receptor.

Strockbine LD, Cohen JI, Farrah T, Lyman SD, Wagener F, DuBose RF, Armitage RJ, Spriggs MK.

J Virol. 1998 May;72(5):4015-21.

16.

c-kit ligand and Flt3 ligand: stem/progenitor cell factors with overlapping yet distinct activities.

Lyman SD, Jacobsen SE.

Blood. 1998 Feb 15;91(4):1101-34. Review. No abstract available.

PMID:
9454740
17.

Thrombopoietin, steel factor and the ligand for flt3/flk2 interact to stimulate the proliferation of human hematopoietic progenitors in culture.

Kobayashi M, Laver JH, Lyman SD, Kato T, Miyazaki H, Ogawa M.

Int J Hematol. 1997 Dec;66(4):423-34.

PMID:
9479869
18.

Synergistic action of Flt3 and gp130 signalings in human hematopoiesis.

Ebihara Y, Tsuji K, Lyman SD, Sui X, Yoshida M, Muraoka K, Yamada K, Tanaka R, Nakahata T.

Blood. 1997 Dec 1;90(11):4363-8.

PMID:
9373247
19.
20.

Flt3 ligand enhances the yield of primitive cells after Ex vivo cultivation of CD34+ CD38dim cells and CD34+ CD38dim CD33dim HLA-DR+ cells.

Dooley DC, Xiao M, Oppenlander BK, Plunkett JM, Lyman SD.

Blood. 1997 Nov 15;90(10):3903-13.

PMID:
9354657
22.

Efficient retrovirus-mediated gene transfer of dendritic cells generated from CD34+ cord blood cells under serum-free conditions.

Bello-Fernandez C, Matyash M, Strobl H, Pickl WF, Majdic O, Lyman SD, Knapp W.

Hum Gene Ther. 1997 Sep 20;8(14):1651-8.

PMID:
9322867
24.
25.

Effect of flt3 ligand on in vitro growth and expansion of colony-forming bone marrow cells from patients with aplastic anemia.

Wodnar-Filipowicz A, Chklovskaia E, Manz CY, Lyman SD, Nissen C.

Exp Hematol. 1997 Jul;25(7):573-81.

PMID:
9216732
26.

Human FLT3 ligand acts on myeloid as well as multipotential progenitors derived from purified CD34+ blood progenitors expressing different levels of c-kit protein.

Sonoda Y, Kimura T, Sakabe H, Tanimukai S, Ohmizono Y, Nakagawa S, Yokota S, Lyman SD, Abe T.

Eur J Haematol. 1997 Apr;58(4):257-64.

PMID:
9186537
27.

Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand.

Ohmizono Y, Sakabe H, Kimura T, Tanimukai S, Matsumura T, Miyazaki H, Lyman SD, Sonoda Y.

Leukemia. 1997 Apr;11(4):524-30.

28.
29.

Dramatic numerical increase of functionally mature dendritic cells in FLT3 ligand-treated mice.

Maraskovsky E, Pulendran B, Brasel K, Teepe M, Roux ER, Shortman K, Lyman SD, McKenna HJ.

Adv Exp Med Biol. 1997;417:33-40. Review. No abstract available.

PMID:
9286334
30.

Retroviral mediated gene transfer of Flt3 ligand enhances proliferation and MAP kinase activity of AML5 cells.

Braun SE, Aronica SM, Ge Y, Takahira H, Etienne-Julan M, Lu L, Minden MD, Lyman SD, Broxmeyer HE.

Exp Hematol. 1997 Jan;25(1):51-6.

PMID:
8989907
31.

Flt3 ligand level reflects hematopoietic progenitor cell function in aplastic anemia and chemotherapy-induced bone marrow aplasia.

Wodnar-Filipowicz A, Lyman SD, Gratwohl A, Tichelli A, Speck B, Nissen C.

Blood. 1996 Dec 15;88(12):4493-9.

PMID:
8977241
33.
35.

Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.

Maraskovsky E, Brasel K, Teepe M, Roux ER, Lyman SD, Shortman K, McKenna HJ.

J Exp Med. 1996 Nov 1;184(5):1953-62.

36.

FLT3 receptor expression on the surface of normal and malignant human hematopoietic cells.

Turner AM, Lin NL, Issarachai S, Lyman SD, Broudy VC.

Blood. 1996 Nov 1;88(9):3383-90.

PMID:
8896403
38.

Hematologic effects of flt3 ligand in vivo in mice.

Brasel K, McKenna HJ, Morrissey PJ, Charrier K, Morris AE, Lee CC, Williams DE, Lyman SD.

Blood. 1996 Sep 15;88(6):2004-12.

PMID:
8822919
40.

Flt3 ligand supports the differentiation of early B cell progenitors in the presence of interleukin-11 and interleukin-7.

Ray RJ, Paige CJ, Furlonger C, Lyman SD, Rottapel R.

Eur J Immunol. 1996 Jul;26(7):1504-10.

PMID:
8766553
42.

Flt3-ligand production by human bone marrow stromal cells.

Lisovsky M, Braun SE, Ge Y, Takahira H, Lu L, Savchenko VG, Lyman SD, Broxmeyer HE.

Leukemia. 1996 Jun;10(6):1012-8.

PMID:
8667636
43.

Stem cell factor, but not flt3 ligand, induces differentiation and activation of human mast cells.

Hjertson M, Sundström C, Lyman SD, Nilsson K, Nilsson G.

Exp Hematol. 1996 May;24(6):748-54.

PMID:
8635531
44.

The genes encoding the eph-related receptor tyrosine kinase ligands LERK-1 (EPLG1, Epl1), LERK-3 (EPLG3, Epl3), and LERK-4 (EPLG4, Epl4) are clustered on human chromosome 1 and mouse chromosome 3.

Cerretti DP, Lyman SD, Kozlosky CJ, Copeland NG, Gilbert DJ, Jenkins NA, Valentine V, Kirstein MN, Shapiro DN, Morris SW.

Genomics. 1996 Apr 15;33(2):277-82.

PMID:
8660976
45.
46.

Accelerated cell-cycling of hematopoietic progenitors by the flt3 ligand that is modulated by transforming growth factor-beta.

Ohishi K, Katayama N, Itoh R, Mahmud N, Miwa H, Kita K, Minami N, Shirakawa S, Lyman SD, Shiku H.

Blood. 1996 Mar 1;87(5):1718-27.

PMID:
8634417
47.
48.

Effects of flt3 ligand on acute myeloid and lymphocytic leukemic blast cells from children.

McKenna HJ, Smith FO, Brasel K, Hirschstein D, Bernstein ID, Williams DE, Lyman SD.

Exp Hematol. 1996 Feb;24(2):378-85.

PMID:
8641369
49.

Effects of Flt3 ligand and interleukin-7 on in vitro growth of acute lymphoblastic leukemia cells.

Eder M, Hemmati P, Kalina U, Ottman OG, Hoelzer D, Lyman SD, Ganser A.

Exp Hematol. 1996 Feb;24(2):371-7.

PMID:
8641368
50.

Isolation and characterization of primitive hematopoietic progenitors of murine fetal liver.

Fujimoto K, Lyman SD, Hiryama F, Ogawa M.

Exp Hematol. 1996 Feb;24(2):285-90.

PMID:
8641354

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