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Items: 1 to 50 of 56

1.

Chromatin Modification and Global Transcriptional Silencing in the Oocyte Mediated by the mRNA Decay Activator ZFP36L2.

Dumdie JN, Cho K, Ramaiah M, Skarbrevik D, Mora-Castilla S, Stumpo DJ, Lykke-Andersen J, Laurent LC, Blackshear PJ, Wilkinson MF, Cook-Andersen H.

Dev Cell. 2018 Feb 5;44(3):392-402.e7. doi: 10.1016/j.devcel.2018.01.006. Epub 2018 Feb 5.

2.

Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing.

Lardelli RM, Schaffer AE, Eggens VR, Zaki MS, Grainger S, Sathe S, Van Nostrand EL, Schlachetzki Z, Rosti B, Akizu N, Scott E, Silhavy JL, Heckman LD, Rosti RO, Dikoglu E, Gregor A, Guemez-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, Marin-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, Blaser S, Çağlayan AO, Bilguvar K, Per H, Fagerberg C, Christesen HT, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi NC, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Nassogne MC, Bennett EJ, Yeo GW, Baas F, Lykke-Andersen J, Gleeson JG.

Nat Genet. 2017 Mar;49(3):457-464. doi: 10.1038/ng.3762. Epub 2017 Jan 16.

3.

A human microprotein that interacts with the mRNA decapping complex.

D'Lima NG, Ma J, Winkler L, Chu Q, Loh KH, Corpuz EO, Budnik BA, Lykke-Andersen J, Saghatelian A, Slavoff SA.

Nat Chem Biol. 2017 Feb;13(2):174-180. doi: 10.1038/nchembio.2249. Epub 2016 Dec 5.

4.

Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System.

Martinez FJ, Pratt GA, Van Nostrand EL, Batra R, Huelga SC, Kapeli K, Freese P, Chun SJ, Ling K, Gelboin-Burkhart C, Fijany L, Wang HC, Nussbacher JK, Broski SM, Kim HJ, Lardelli R, Sundararaman B, Donohue JP, Javaherian A, Lykke-Andersen J, Finkbeiner S, Bennett CF, Ares M Jr, Burge CB, Taylor JP, Rigo F, Yeo GW.

Neuron. 2016 Nov 23;92(4):780-795. doi: 10.1016/j.neuron.2016.09.050. Epub 2016 Oct 20.

5.

Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay.

Durand S, Franks TM, Lykke-Andersen J.

Nat Commun. 2016 Aug 11;7:12434. doi: 10.1038/ncomms12434.

6.

The C-Terminal RGG Domain of Human Lsm4 Promotes Processing Body Formation Stimulated by Arginine Dimethylation.

Arribas-Layton M, Dennis J, Bennett EJ, Damgaard CK, Lykke-Andersen J.

Mol Cell Biol. 2016 Aug 12;36(17):2226-35. doi: 10.1128/MCB.01102-15. Print 2016 Sep 1.

7.

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements.

Fu R, Olsen MT, Webb K, Bennett EJ, Lykke-Andersen J.

RNA. 2016 Mar;22(3):373-82. doi: 10.1261/rna.054833.115. Epub 2016 Jan 13.

8.

DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways.

Wang Y, Arribas-Layton M, Chen Y, Lykke-Andersen J, Sen GL.

Mol Cell. 2015 Oct 1;60(1):118-30. doi: 10.1016/j.molcel.2015.08.014. Epub 2015 Sep 24.

9.

Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity.

Lee SR, Pratt GA, Martinez FJ, Yeo GW, Lykke-Andersen J.

Mol Cell. 2015 Aug 6;59(3):413-25. doi: 10.1016/j.molcel.2015.06.036.

10.

Competition between Decapping Complex Formation and Ubiquitin-Mediated Proteasomal Degradation Controls Human Dcp2 Decapping Activity.

Erickson SL, Corpuz EO, Maloy JP, Fillman C, Webb K, Bennett EJ, Lykke-Andersen J.

Mol Cell Biol. 2015 Jun;35(12):2144-53. doi: 10.1128/MCB.01517-14. Epub 2015 Apr 13.

11.

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay.

Hausburg MA, Doles JD, Clement SL, Cadwallader AB, Hall MN, Blackshear PJ, Lykke-Andersen J, Olwin BB.

Elife. 2015 Mar 27;4:e03390. doi: 10.7554/eLife.03390.

12.

Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.

Toma KG, Rebbapragada I, Durand S, Lykke-Andersen J.

RNA. 2015 May;21(5):887-97. doi: 10.1261/rna.048637.114. Epub 2015 Mar 24.

13.

hnRNP F complexes with tristetraprolin and stimulates ARE-mRNA decay.

Reznik B, Clement SL, Lykke-Andersen J.

PLoS One. 2014 Jun 30;9(6):e100992. doi: 10.1371/journal.pone.0100992. eCollection 2014.

14.

Protecting the proteome: Eukaryotic cotranslational quality control pathways.

Lykke-Andersen J, Bennett EJ.

J Cell Biol. 2014 Feb 17;204(4):467-76. doi: 10.1083/jcb.201311103. Review.

15.

Regulation of ARE-mRNA Stability by Cellular Signaling: Implications for Human Cancer.

Damgaard CK, Lykke-Andersen J.

Cancer Treat Res. 2013;158:153-80. doi: 10.1007/978-3-642-31659-3_7.

PMID:
24222358
16.

Emerging roles for ribonucleoprotein modification and remodeling in controlling RNA fate.

Lee SR, Lykke-Andersen J.

Trends Cell Biol. 2013 Oct;23(10):504-10. doi: 10.1016/j.tcb.2013.05.001. Epub 2013 Jun 4. Review.

17.

Nonsense-mediated mRNA decay occurs during eIF4F-dependent translation in human cells.

Durand S, Lykke-Andersen J.

Nat Struct Mol Biol. 2013 Jun;20(6):702-9. doi: 10.1038/nsmb.2575. Epub 2013 May 12.

PMID:
23665580
18.

Structural and functional control of the eukaryotic mRNA decapping machinery.

Arribas-Layton M, Wu D, Lykke-Andersen J, Song H.

Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):580-9. doi: 10.1016/j.bbagrm.2012.12.006. Epub 2012 Dec 31. Review.

19.

mRNA decapping factors and the exonuclease Xrn2 function in widespread premature termination of RNA polymerase II transcription.

Brannan K, Kim H, Erickson B, Glover-Cutter K, Kim S, Fong N, Kiemele L, Hansen K, Davis R, Lykke-Andersen J, Bentley DL.

Mol Cell. 2012 May 11;46(3):311-24. doi: 10.1016/j.molcel.2012.03.006. Epub 2012 Apr 5.

20.

Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.

Damgaard CK, Lykke-Andersen J.

Genes Dev. 2011 Oct 1;25(19):2057-68. doi: 10.1101/gad.17355911.

21.

SnapShot: Nonsense-mediated mRNA decay.

Durand S, Lykke-Andersen J.

Cell. 2011 Apr 15;145(2):324-324.e2. doi: 10.1016/j.cell.2011.03.038. No abstract available.

22.

Cytoplasmic mRNP granules at a glance.

Erickson SL, Lykke-Andersen J.

J Cell Sci. 2011 Feb 1;124(Pt 3):293-7. doi: 10.1242/jcs.072140. Review. No abstract available.

23.

Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay.

Franks TM, Singh G, Lykke-Andersen J.

Cell. 2010 Dec 10;143(6):938-50. doi: 10.1016/j.cell.2010.11.043.

24.

Regulated and quality-control mRNA turnover pathways in eukaryotes.

Reznik B, Lykke-Andersen J.

Biochem Soc Trans. 2010 Dec;38(6):1506-10. doi: 10.1042/BST0381506.

PMID:
21118116
25.

Phosphorylation of tristetraprolin by MK2 impairs AU-rich element mRNA decay by preventing deadenylase recruitment.

Clement SL, Scheckel C, Stoecklin G, Lykke-Andersen J.

Mol Cell Biol. 2011 Jan;31(2):256-66. doi: 10.1128/MCB.00717-10. Epub 2010 Nov 15.

26.

How and where are nonsense mRNAs degraded in mammalian cells?

Mühlemann O, Lykke-Andersen J.

RNA Biol. 2010 Jan-Feb;7(1):28-32. Epub 2010 Jan 9.

27.

Execution of nonsense-mediated mRNA decay: what defines a substrate?

Rebbapragada I, Lykke-Andersen J.

Curr Opin Cell Biol. 2009 Jun;21(3):394-402. doi: 10.1016/j.ceb.2009.02.007. Epub 2009 Apr 7. Review.

PMID:
19359157
28.

The control of mRNA decapping and P-body formation.

Franks TM, Lykke-Andersen J.

Mol Cell. 2008 Dec 5;32(5):605-15. doi: 10.1016/j.molcel.2008.11.001. Review.

29.

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay.

Singh G, Rebbapragada I, Lykke-Andersen J.

PLoS Biol. 2008 Apr 29;6(4):e111. doi: 10.1371/journal.pbio.0060111.

30.

A tethering approach to study proteins that activate mRNA turnover in human cells.

Clement SL, Lykke-Andersen J.

Methods Mol Biol. 2008;419:121-33. doi: 10.1007/978-1-59745-033-1_8.

PMID:
18369979
31.
32.
33.

An unconventional human Ccr4-Caf1 deadenylase complex in nuclear cajal bodies.

Wagner E, Clement SL, Lykke-Andersen J.

Mol Cell Biol. 2007 Mar;27(5):1686-95. Epub 2006 Dec 18.

34.

No mercy for messages that mess with the ribosome.

Clement SL, Lykke-Andersen J.

Nat Struct Mol Biol. 2006 Apr;13(4):299-301. No abstract available.

PMID:
16715045
35.

Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

Fenger-Grøn M, Fillman C, Norrild B, Lykke-Andersen J.

Mol Cell. 2005 Dec 22;20(6):905-15.

36.

Messenger RNA surveillance: neutralizing natural nonsense.

Weischenfeldt J, Lykke-Andersen J, Porse B.

Curr Biol. 2005 Jul 26;15(14):R559-62. Review.

37.

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling.

Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, Scheuner D, Kaufman RJ, Golan DE, Anderson P.

J Cell Biol. 2005 Jun 20;169(6):871-84.

38.

RNA decapping inside and outside of processing bodies.

Fillman C, Lykke-Andersen J.

Curr Opin Cell Biol. 2005 Jun;17(3):326-31. Review.

PMID:
15901504
40.

Making structural sense of nonsense-mediated decay.

Lykke-Andersen J.

Nat Struct Mol Biol. 2004 Apr;11(4):305-6. No abstract available.

PMID:
15048104
41.

New insights into the formation of active nonsense-mediated decay complexes.

Singh G, Lykke-Andersen J.

Trends Biochem Sci. 2003 Sep;28(9):464-6. Review.

PMID:
13678954
42.

Nuclear transit of human zipcode-binding protein IMP1.

Nielsen J, Adolph SK, Rajpert-De Meyts E, Lykke-Andersen J, Koch G, Christiansen J, Nielsen FC.

Biochem J. 2003 Dec 1;376(Pt 2):383-91.

43.
44.

mRNA surveillance: the perfect persist.

Wagner E, Lykke-Andersen J.

J Cell Sci. 2002 Aug 1;115(Pt 15):3033-8. Review.

45.
46.

mRNA quality control: Marking the message for life or death.

Lykke-Andersen J.

Curr Biol. 2001 Feb 6;11(3):R88-91. Review.

47.
48.

H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein.

Runge S, Nielsen FC, Nielsen J, Lykke-Andersen J, Wewer UM, Christiansen J.

J Biol Chem. 2000 Sep 22;275(38):29562-9.

49.

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.

Nielsen J, Christiansen J, Lykke-Andersen J, Johnsen AH, Wewer UM, Nielsen FC.

Mol Cell Biol. 1999 Feb;19(2):1262-70.

50.

The C-terminal carboxy group of T7 RNA polymerase ensures efficient magnesium ion-dependent catalysis.

Lykke-Andersen J, Christiansen J.

Nucleic Acids Res. 1998 Dec 15;26(24):5630-5.

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