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Items: 49

1.

Publisher Correction: Claudin-3-deficient C57BL/6J mice display intact brain barriers.

Dias MC, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B.

Sci Rep. 2019 Jul 18;9(1):10702. doi: 10.1038/s41598-019-43511-0.

2.

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation.

Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller WA, Lassmann H, Engelhardt B.

Front Immunol. 2019 Apr 5;10:711. doi: 10.3389/fimmu.2019.00711. eCollection 2019.

3.

Claudin-3-deficient C57BL/6J mice display intact brain barriers.

Castro Dias M, Coisne C, Lazarevic I, Baden P, Hata M, Iwamoto N, Francisco DMF, Vanlandewijck M, He L, Baier FA, Stroka D, Bruggmann R, Lyck R, Enzmann G, Deutsch U, Betsholtz C, Furuse M, Tsukita S, Engelhardt B.

Sci Rep. 2019 Jan 18;9(1):203. doi: 10.1038/s41598-018-36731-3. Erratum in: Sci Rep. 2019 Jul 18;9(1):10702.

4.

HIV-1 Nef Disrupts CD4+ T Lymphocyte Polarity, Extravasation, and Homing to Lymph Nodes via Its Nef-Associated Kinase Complex Interface.

Lamas-Murua M, Stolp B, Kaw S, Thoma J, Tsopoulidis N, Trautz B, Ambiel I, Reif T, Arora S, Imle A, Tibroni N, Wu J, Cui G, Stein JV, Tanaka M, Lyck R, Fackler OT.

J Immunol. 2018 Nov 1;201(9):2731-2743. doi: 10.4049/jimmunol.1701420. Epub 2018 Sep 26.

5.

The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells.

Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, Lyck R, Balmer J, Fiocchi A, Kreutzfeldt M, Merkler D, Iannacone M, Ariga A, Stoffel MH, Sharpe J, Bähler M, Sixt M, Diz-Muñoz A, Stein JV.

J Exp Med. 2018 Jul 2;215(7):1869-1890. doi: 10.1084/jem.20170896. Epub 2018 Jun 6.

6.

VLA-4 mediated adhesion of melanoma cells on the blood-brain barrier is the critical cue for melanoma cell intercalation and barrier disruption.

García-Martín AB, Zwicky P, Gruber T, Matti C, Moalli F, Stein JV, Francisco D, Enzmann G, Levesque MP, Hewer E, Lyck R.

J Cereb Blood Flow Metab. 2019 Oct;39(10):1995-2010. doi: 10.1177/0271678X18775887. Epub 2018 May 15.

PMID:
29762071
7.

ZAP70 expression enhances chemokine-driven chronic lymphocytic leukemia cell migration and arrest by valency regulation of integrins.

Laufer JM, Lyck R, Legler DF.

FASEB J. 2018 Sep;32(9):4824-4835. doi: 10.1096/fj.201701452RR. Epub 2018 Mar 28.

PMID:
29589978
8.

The ESRP1-GPR137 axis contributes to intestinal pathogenesis.

Mager LF, Koelzer VH, Stuber R, Thoo L, Keller I, Koeck I, Langenegger M, Simillion C, Pfister SP, Faderl M, Genitsch V, Tcymbarevich I, Juillerat P, Li X, Xia Y, Karamitopoulou E, Lyck R, Zlobec I, Hapfelmeier S, Bruggmann R, McCoy KD, Macpherson AJ, Müller C, Beutler B, Krebs P.

Elife. 2017 Oct 4;6. pii: e28366. doi: 10.7554/eLife.28366.

9.

Cellular Shuttles: Monocytes/Macrophages Exhibit Transendothelial Transport of Nanoparticles under Physiological Flow.

Moore TL, Hauser D, Gruber T, Rothen-Rutishauser B, Lattuada M, Petri-Fink A, Lyck R.

ACS Appl Mater Interfaces. 2017 Jun 7;9(22):18501-18511. doi: 10.1021/acsami.7b03479. Epub 2017 May 30.

PMID:
28517937
10.

Corrigendum: WNK1 kinase balances T cell adhesion versus migration in vivo.

Köchl R, Thelen F, Vanes L, Brazão TF, Fountain K, Xie J, Huang CL, Lyck R, Stein JV, Tybulewicz VL.

Nat Immunol. 2017 Jan 19;18(2):246. doi: 10.1038/ni0217-246a. No abstract available.

PMID:
28102214
11.

Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis.

Lécuyer MA, Saint-Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, Charabati M, Abadier M, Zandee S, Haghayegh Jahromi N, Gowing E, Pittet C, Lyck R, Engelhardt B, Prat A.

Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E524-E533. doi: 10.1073/pnas.1614336114. Epub 2017 Jan 9.

12.

WNK1 kinase balances T cell adhesion versus migration in vivo.

Köchl R, Thelen F, Vanes L, Brazão TF, Fountain K, Xie J, Huang CL, Lyck R, Stein JV, Tybulewicz VL.

Nat Immunol. 2016 Sep;17(9):1075-83. doi: 10.1038/ni.3495. Epub 2016 Jul 11. Erratum in: Nat Immunol. 2017 Jan 19;18(2):246.

13.

Postarrest stalling rather than crawling favors CD8(+) over CD4(+) T-cell migration across the blood-brain barrier under flow in vitro.

Rudolph H, Klopstein A, Gruber I, Blatti C, Lyck R, Engelhardt B.

Eur J Immunol. 2016 Sep;46(9):2187-203. doi: 10.1002/eji.201546251. Epub 2016 Jul 22.

14.

The machinery underlying malaria parasite virulence is conserved between rodent and human malaria parasites.

De Niz M, Ullrich AK, Heiber A, Blancke Soares A, Pick C, Lyck R, Keller D, Kaiser G, Prado M, Flemming S, Del Portillo H, Janse CJ, Heussler V, Spielmann T.

Nat Commun. 2016 May 26;7:11659. doi: 10.1038/ncomms11659.

15.

Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments.

Imeri F, Schwalm S, Lyck R, Zivkovic A, Stark H, Engelhardt B, Pfeilschifter J, Huwiler A.

Neuropharmacology. 2016 Jun;105:341-350. doi: 10.1016/j.neuropharm.2016.01.031. Epub 2016 Jan 23.

PMID:
26808312
16.

ALCAM (CD166) is involved in extravasation of monocytes rather than T cells across the blood-brain barrier.

Lyck R, Lécuyer MA, Abadier M, Wyss CB, Matti C, Rosito M, Enzmann G, Zeis T, Michel L, García Martín AB, Sallusto F, Gosselet F, Deutsch U, Weiner JA, Schaeren-Wiemers N, Prat A, Engelhardt B.

J Cereb Blood Flow Metab. 2017 Aug;37(8):2894-2909. doi: 10.1177/0271678X16678639. Epub 2016 Nov 14.

17.

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke.

Lopes Pinheiro MA, Kooij G, Mizee MR, Kamermans A, Enzmann G, Lyck R, Schwaninger M, Engelhardt B, de Vries HE.

Biochim Biophys Acta. 2016 Mar;1862(3):461-71. doi: 10.1016/j.bbadis.2015.10.018. Epub 2015 Oct 23. Review.

18.

Cell surface levels of endothelial ICAM-1 influence the transcellular or paracellular T-cell diapedesis across the blood-brain barrier.

Abadier M, Haghayegh Jahromi N, Cardoso Alves L, Boscacci R, Vestweber D, Barnum S, Deutsch U, Engelhardt B, Lyck R.

Eur J Immunol. 2015 Apr;45(4):1043-58. doi: 10.1002/eji.201445125. Epub 2015 Jan 23.

19.

The physiological roles of ICAM-1 and ICAM-2 in neutrophil migration into tissues.

Lyck R, Enzmann G.

Curr Opin Hematol. 2015 Jan;22(1):53-9. doi: 10.1097/MOH.0000000000000103. Review.

20.

The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions.

Steiner E, Enzmann GU, Lyck R, Lin S, Rüegg MA, Kröger S, Engelhardt B.

Cell Tissue Res. 2014 Nov;358(2):465-79. doi: 10.1007/s00441-014-1969-7. Epub 2014 Aug 9.

21.

DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation.

Minten C, Alt C, Gentner M, Frei E, Deutsch U, Lyck R, Schaeren-Wiemers N, Rot A, Engelhardt B.

Brain. 2014 May;137(Pt 5):1454-69. doi: 10.1093/brain/awu045. Epub 2014 Mar 12.

22.

β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier.

Gorina R, Lyck R, Vestweber D, Engelhardt B.

J Immunol. 2014 Jan 1;192(1):324-37. doi: 10.4049/jimmunol.1300858. Epub 2013 Nov 20.

23.

Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.

Moretti FA, Moser M, Lyck R, Abadier M, Ruppert R, Engelhardt B, Fässler R.

Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):17005-10. doi: 10.1073/pnas.1316032110. Epub 2013 Oct 2.

24.

Ezrin/Radixin/Moesin proteins and flotillins cooperate to promote uropod formation in T cells.

Martinelli S, Chen EJ, Clarke F, Lyck R, Affentranger S, Burkhardt JK, Niggli V.

Front Immunol. 2013 Apr 8;4:84. doi: 10.3389/fimmu.2013.00084. eCollection 2013.

25.

Live cell imaging techniques to study T cell trafficking across the blood-brain barrier in vitro and in vivo.

Coisne C, Lyck R, Engelhardt B.

Fluids Barriers CNS. 2013 Jan 21;10(1):7. doi: 10.1186/2045-8118-10-7.

26.

HIV-1 Nef interferes with T-lymphocyte circulation through confined environments in vivo.

Stolp B, Imle A, Coelho FM, Hons M, Gorina R, Lyck R, Stein JV, Fackler OT.

Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18541-6. doi: 10.1073/pnas.1204322109. Epub 2012 Oct 23.

27.

Going against the tide--how encephalitogenic T cells breach the blood-brain barrier.

Lyck R, Engelhardt B.

J Vasc Res. 2012;49(6):497-509. doi: 10.1159/000341232. Epub 2012 Aug 29. Review.

28.

Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation.

Nitschké M, Aebischer D, Abadier M, Haener S, Lucic M, Vigl B, Luche H, Fehling HJ, Biehlmaier O, Lyck R, Halin C.

Blood. 2012 Sep 13;120(11):2249-58. doi: 10.1182/blood-2012-03-417923. Epub 2012 Jul 31.

PMID:
22855606
29.

Claudin-1 induced sealing of blood-brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis.

Pfeiffer F, Schäfer J, Lyck R, Makrides V, Brunner S, Schaeren-Wiemers N, Deutsch U, Engelhardt B.

Acta Neuropathol. 2011 Nov;122(5):601-14. doi: 10.1007/s00401-011-0883-2. Epub 2011 Oct 9.

30.

In vivo analysis of uropod function during physiological T cell trafficking.

Soriano SF, Hons M, Schumann K, Kumar V, Dennier TJ, Lyck R, Sixt M, Stein JV.

J Immunol. 2011 Sep 1;187(5):2356-64. doi: 10.4049/jimmunol.1100935. Epub 2011 Jul 27.

31.

Differential expression of the bone and the liver tissue non-specific alkaline phosphatase isoforms in brain tissues.

Brun-Heath I, Ermonval M, Chabrol E, Xiao J, Palkovits M, Lyck R, Miller F, Couraud PO, Mornet E, Fonta C.

Cell Tissue Res. 2011 Mar;343(3):521-36. doi: 10.1007/s00441-010-1111-4. Epub 2010 Dec 31.

PMID:
21191615
32.

Review: leucocyte-endothelial cell crosstalk at the blood-brain barrier: a prerequisite for successful immune cell entry to the brain.

Greenwood J, Heasman SJ, Alvarez JI, Prat A, Lyck R, Engelhardt B.

Neuropathol Appl Neurobiol. 2011 Feb;37(1):24-39. doi: 10.1111/j.1365-2990.2010.01140.x. Review.

PMID:
20946472
33.

Critical roles for Rac GTPases in T-cell migration to and within lymph nodes.

Faroudi M, Hons M, Zachacz A, Dumont C, Lyck R, Stein JV, Tybulewicz VL.

Blood. 2010 Dec 16;116(25):5536-47. doi: 10.1182/blood-2010-08-299438. Epub 2010 Sep 24.

34.

Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium.

Steiner O, Coisne C, Cecchelli R, Boscacci R, Deutsch U, Engelhardt B, Lyck R.

J Immunol. 2010 Oct 15;185(8):4846-55. doi: 10.4049/jimmunol.0903732. Epub 2010 Sep 22.

35.

Comparison of immortalized bEnd5 and primary mouse brain microvascular endothelial cells as in vitro blood-brain barrier models for the study of T cell extravasation.

Steiner O, Coisne C, Engelhardt B, Lyck R.

J Cereb Blood Flow Metab. 2011 Jan;31(1):315-27. doi: 10.1038/jcbfm.2010.96. Epub 2010 Jul 7.

36.

Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo.

Lyck R, Ruderisch N, Moll AG, Steiner O, Cohen CD, Engelhardt B, Makrides V, Verrey F.

J Cereb Blood Flow Metab. 2009 Sep;29(9):1491-502. doi: 10.1038/jcbfm.2009.72. Epub 2009 Jun 3.

PMID:
19491922
37.

VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.

Nottebaum AF, Cagna G, Winderlich M, Gamp AC, Linnepe R, Polaschegg C, Filippova K, Lyck R, Engelhardt B, Kamenyeva O, Bixel MG, Butz S, Vestweber D.

J Exp Med. 2008 Nov 24;205(12):2929-45. doi: 10.1084/jem.20080406. Epub 2008 Nov 17.

38.

Therapeutic targeting of leukocyte trafficking across the blood-brain barrier.

Coisne C, Lyck R, Engelhardt B.

Inflamm Allergy Drug Targets. 2007 Dec;6(4):210-22. Review.

PMID:
18220956
39.

Migration of immature mouse DC across resting endothelium is mediated by ICAM-2 but independent of beta2-integrins and murine DC-SIGN homologues.

Wethmar K, Helmus Y, Lühn K, Jones C, Laskowska A, Varga G, Grabbe S, Lyck R, Engelhardt B, Bixel MG, Butz S, Loser K, Beissert S, Ipe U, Vestweber D, Wild MK.

Eur J Immunol. 2006 Oct;36(10):2781-94.

40.

Dysferlin is a new marker for leaky brain blood vessels in multiple sclerosis.

Hochmeister S, Grundtner R, Bauer J, Engelhardt B, Lyck R, Gordon G, Korosec T, Kutzelnigg A, Berger JJ, Bradl M, Bittner RE, Lassmann H.

J Neuropathol Exp Neurol. 2006 Sep;65(9):855-65.

PMID:
16957579
41.

Intracellular domain of brain endothelial intercellular adhesion molecule-1 is essential for T lymphocyte-mediated signaling and migration.

Greenwood J, Amos CL, Walters CE, Couraud PO, Lyck R, Engelhardt B, Adamson P.

J Immunol. 2003 Aug 15;171(4):2099-108.

42.

T-cell interaction with ICAM-1/ICAM-2 double-deficient brain endothelium in vitro: the cytoplasmic tail of endothelial ICAM-1 is necessary for transendothelial migration of T cells.

Lyck R, Reiss Y, Gerwin N, Greenwood J, Adamson P, Engelhardt B.

Blood. 2003 Nov 15;102(10):3675-83. Epub 2003 Jul 31.

PMID:
12893765
43.

Isolation and characterization of HsfA3, a new heat stress transcription factor of Lycopersicon peruvianum.

Bharti K, Schmidt E, Lyck R, Heerklotz D, Bublak D, Scharf KD.

Plant J. 2000 May;22(4):355-65.

44.

The role of AHA motifs in the activator function of tomato heat stress transcription factors HsfA1 and HsfA2.

Döring P, Treuter E, Kistner C, Lyck R, Chen A, Nover L.

Plant Cell. 2000 Feb;12(2):265-78.

45.
46.

Heat stress transcription factors from tomato can functionally replace HSF1 in the yeast Saccharomyces cerevisiae.

Boscheinen O, Lyck R, Queitsch C, Treuter E, Zimarino V, Scharf KD.

Mol Gen Genet. 1997 Jul;255(3):322-31.

PMID:
9268023
47.

The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.

Philippsen P, Kleine K, Pöhlmann R, Düsterhöft A, Hamberg K, Hegemann JH, Obermaier B, Urrestarazu LA, Aert R, Albermann K, Altmann R, André B, Baladron V, Ballesta JP, Bécam AM, Beinhauer J, Boskovic J, Buitrago MJ, Bussereau F, Coster F, Crouzet M, D'Angelo M, Dal Pero F, De Antoni A, Del Rey F, Doignon F, Domdey H, Dubois E, Fiedler T, Fleig U, Floeth M, Fritz C, Gaillardin C, Garcia-Cantalejo JM, Glansdorff NN, Goffeau A, Gueldener U, Herbert C, Heumann K, Heuss-Neitzel D, Hilbert H, Hinni K, Iraqui Houssaini I, Jacquet M, Jimenez A, Jonniaux JL, Karpfinger L, Lanfranchi G, Lepingle A, Levesque H, Lyck R, Maftahi M, Mallet L, Maurer KC, Messenguy F, Mewes HW, Mösti D, Nasr F, Nicaud JM, Niedenthal RK, Pandolfo D, Piérard A, Piravandi E, Planta RJ, Pohl TM, Purnelle B, Rebischung C, Remacha M, Revuelta JL, Rinke M, Saiz JE, Sartorello F, Scherens B, Sen-Gupta M, Soler-Mira A, Urbanus JH, Valle G, Van Dyck L, Verhasselt P, Vierendeels F, Vissers S, Voet M, Volckaert G, Wach A, Wambutt R, Wedler H, Zollner A, Hani J.

Nature. 1997 May 29;387(6632 Suppl):93-8.

PMID:
9169873
48.

Intracellular distribution and identification of the nuclear localization signals of two plant heat-stress transcription factors.

Lyck R, Harmening U, Höhfeld I, Treuter E, Scharf KD, Nover L.

Planta. 1997;202(1):117-25.

PMID:
9177056
49.

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