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Items: 21


Directed Differentiation of Human Embryonic Stem Cells Toward Placode-Derived Spiral Ganglion-Like Sensory Neurons.

Matsuoka AJ, Morrissey ZD, Zhang C, Homma K, Belmadani A, Miller CA, Chadly DM, Kobayashi S, Edelbrock AN, Tanaka-Matakatsu M, Whitlon DS, Lyass L, McGuire TL, Stupp SI, Kessler JA.

Stem Cells Transl Med. 2017 Mar;6(3):923-936. doi: 10.1002/sctm.16-0032. Epub 2016 Dec 10.


The controlled generation of functional basal forebrain cholinergic neurons from human embryonic stem cells.

Bissonnette CJ, Lyass L, Bhattacharyya BJ, Belmadani A, Miller RJ, Kessler JA.

Stem Cells. 2011 May;29(5):802-11. doi: 10.1002/stem.626.


Enucleation of feeder cells and egg cells with psoralens.

McGarry TJ, Bonaguidi M, Lyass L, Kessler JA, Bodily JM, Doglio L.

Dev Dyn. 2009 Oct;238(10):2614-21. doi: 10.1002/dvdy.22080.


Activation of AMPK is necessary for killing cancer cells and sparing cardiac cells.

Shell SA, Lyass L, Trusk PB, Pry KJ, Wappel RL, Bacus SS.

Cell Cycle. 2008 Jun 15;7(12):1769-75. Epub 2008 Jun 30.


A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.

Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y.

Nat Cell Biol. 2007 Aug;9(8):961-9. Epub 2007 Jul 22.


Activation of AMP-activated protein kinase by human EGF receptor 2/EGF receptor tyrosine kinase inhibitor protects cardiac cells.

Spector NL, Yarden Y, Smith B, Lyass L, Trusk P, Pry K, Hill JE, Xia W, Seger R, Bacus SS.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10607-12. Epub 2007 Jun 7.


A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer.

Xia W, Bacus S, Hegde P, Husain I, Strum J, Liu L, Paulazzo G, Lyass L, Trusk P, Hill J, Harris J, Spector NL.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7795-800. Epub 2006 May 8.


Synergistic down-regulation of receptor tyrosine kinases by combinations of mAbs: implications for cancer immunotherapy.

Friedman LM, Rinon A, Schechter B, Lyass L, Lavi S, Bacus SS, Sela M, Yarden Y.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1915-20. Epub 2005 Jan 31.


Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity.

Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y.

J Biol Chem. 2005 Mar 4;280(9):8503-12. Epub 2004 Dec 17.


AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival.

Bacus SS, Altomare DA, Lyass L, Chin DM, Farrell MP, Gurova K, Gudkov A, Testa JR.

Oncogene. 2002 May 16;21(22):3532-40.


Taxol-induced apoptosis depends on MAP kinase pathways (ERK and p38) and is independent of p53.

Bacus SS, Gudkov AV, Lowe M, Lyass L, Yung Y, Komarov AP, Keyomarsi K, Yarden Y, Seger R.

Oncogene. 2001 Jan 11;20(2):147-55.


The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

Applebury ML, Antoch MP, Baxter LC, Chun LL, Falk JD, Farhangfar F, Kage K, Krzystolik MG, Lyass LA, Robbins JT.

Neuron. 2000 Sep;27(3):513-23.


ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.

Pinkas-Kramarski R, Shelly M, Guarino BC, Wang LM, Lyass L, Alroy I, Alimandi M, Kuo A, Moyer JD, Lavi S, Eisenstein M, Ratzkin BJ, Seger R, Bacus SS, Pierce JH, Andrews GC, Yarden Y.

Mol Cell Biol. 1998 Oct;18(10):6090-101. Erratum in: Mol Cell Biol 1998 Dec;18(12):7602. Alamandi M [corrected to Alimandi M].


Epiregulin is a potent pan-ErbB ligand that preferentially activates heterodimeric receptor complexes.

Shelly M, Pinkas-Kramarski R, Guarino BC, Waterman H, Wang LM, Lyass L, Alimandi M, Kuo A, Bacus SS, Pierce JH, Andrews GC, Yarden Y.

J Biol Chem. 1998 Apr 24;273(17):10496-505.


The oncogenic ErbB-2/ErbB-3 heterodimer is a surrogate receptor of the epidermal growth factor and betacellulin.

Pinkas-Kramarski R, Lenferink AE, Bacus SS, Lyass L, van de Poll ML, Klapper LN, Tzahar E, Sela M, van Zoelen EJ, Yarden Y.

Oncogene. 1998 Mar 12;16(10):1249-58.


Neu differentiation factor (Heregulin) activates a p53-dependent pathway in cancer cells.

Bacus SS, Yarden Y, Oren M, Chin DM, Lyass L, Zelnick CR, Kazarov A, Toyofuku W, Gray-Bablin J, Beerli RR, Hynes NE, Nikiforov M, Haffner R, Gudkov A, Keyomarsi K.

Oncogene. 1996 Jun 20;12(12):2535-47.


Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.

Ahmed M, Lyass L, Markham PN, Taylor SS, Vázquez-Laslop N, Neyfakh AA.

J Bacteriol. 1995 Jul;177(14):3904-10.


Cytoskeletal reorganizations responsible for the phorbol ester-induced formation of cytoplasmic processes: possible involvement of intermediate filaments.

Bershadsky AD, Ivanova OY, Lyass LA, Pletyushkina OY, Vasiliev JM, Gelfand IM.

Proc Natl Acad Sci U S A. 1990 Mar;87(5):1884-8.


Microtubule-dependent effect of phorbol ester on the contractility of cytoskeleton of cultured fibroblasts.

Lyass LA, Bershadsky AD, Vasiliev JM, Gelfand IM.

Proc Natl Acad Sci U S A. 1988 Dec;85(24):9538-41.


Multinucleation-induced improvement of the spreading of transformed cells on the substratum.

Lyass LA, Bershadsky AD, Gelfand VI, Serpinskaya AS, Stavrovskaya AA, Vasiliev JM, Gelfand IM.

Proc Natl Acad Sci U S A. 1984 May;81(10):3098-102.


The effects of increased osmotic pressure on focal contacts and microfilament bundles of cultured fibroblasts.

Lyass LA, Svitkina TM, Vasiliev JM.

Exp Cell Res. 1982 Oct;141(2):488-92. No abstract available.


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