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Items: 35

1.

Common Metabolic Pathways Implicated in Resistance to Chemotherapy Point to a Key Mitochondrial Role in Breast Cancer.

Abad E, García-Mayea Y, Mir C, Sebastian D, Zorzano A, Potesil D, Zdrahal Z, Lyakhovich A, Lleonart ME.

Mol Cell Proteomics. 2019 Feb;18(2):231-244. doi: 10.1074/mcp.RA118.001102. Epub 2018 Oct 29.

PMID:
30373788
2.

miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer.

Feliciano A, Garcia-Mayea Y, Jubierre L, Mir C, Hummel M, Castellvi J, Hernández-Losa J, Paciucci R, Sansano I, Sun Y, Ramón Y Cajal S, Kondon H, Soriano A, Segura M, Lyakhovich A, LLeonart ME.

Cell Death Dis. 2017 Oct 26;8(10):e3141. doi: 10.1038/cddis.2017.544.

3.

Absence of Relationship between Mitochondrial DNA Haplogroups and Cisplatin-Induced Hearing Loss.

Graterol D, Mir C, Garcia-Vaquero C, Braña I, Pardo AN, Rochera-Villach MI, Lyakhovich A, LLeonart ME, Lorente J.

Int J Otolaryngol. 2017;2017:5185268. doi: 10.1155/2017/5185268. Epub 2017 Jul 3.

4.

Reactive Oxygen Species-Mediated Autophagy Defines the Fate of Cancer Stem Cells.

Lleonart ME, Abad E, Graifer D, Lyakhovich A.

Antioxid Redox Signal. 2017 Aug 4. doi: 10.1089/ars.2017.7223. [Epub ahead of print]

PMID:
28683561
5.

Mitochondrial dysfunction and potential anticancer therapy.

Lleonart ME, Grodzicki R, Graifer DM, Lyakhovich A.

Med Res Rev. 2017 Nov;37(6):1275-1298. doi: 10.1002/med.21459. Epub 2017 Jul 6. Review.

PMID:
28682452
6.

The interplay between autophagy and tumorigenesis: exploiting autophagy as a means of anticancer therapy.

Lorente J, Velandia C, Leal JA, Garcia-Mayea Y, Lyakhovich A, Kondoh H, LLeonart ME.

Biol Rev Camb Philos Soc. 2018 Feb;93(1):152-165. doi: 10.1111/brv.12337. Epub 2017 May 2. Review.

PMID:
28464404
7.

Targeting cancer cells through antibiotics-induced mitochondrial dysfunction requires autophagy inhibition.

Esner M, Graifer D, Lleonart ME, Lyakhovich A.

Cancer Lett. 2017 Jan 1;384:60-69. doi: 10.1016/j.canlet.2016.09.023. Epub 2016 Sep 28.

PMID:
27693455
8.

Impaired mitophagy in Fanconi anemia is dependent on mitochondrial fission.

Shyamsunder P, Esner M, Barvalia M, Wu YJ, Loja T, Boon HB, Lleonart ME, Verma RS, Krejci L, Lyakhovich A.

Oncotarget. 2016 Sep 6;7(36):58065-58074. doi: 10.18632/oncotarget.11161.

9.

Mitochondrial dysfunction in DDR-related cancer predisposition syndromes.

Lyakhovich A, Graifer D, Stefanovie B, Krejci L.

Biochim Biophys Acta. 2016 Apr;1865(2):184-9. doi: 10.1016/j.bbcan.2016.02.006. Epub 2016 Feb 27. Review.

PMID:
26926806
10.

Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and Radiotherapy.

Lyakhovich A, Lleonart ME.

Oxid Med Cell Longev. 2016;2016:1716341. doi: 10.1155/2016/1716341. Epub 2015 Nov 30. Review.

11.

Mitochondria-Mediated Oxidative Stress: Old Target for New Drugs.

Lyakhovich A, Graifer D.

Curr Med Chem. 2015;22(26):3040-53. Review.

PMID:
26219394
12.

ROMO1 regulates RedOx states and serves as an inducer of NF-κB-driven EMT factors in Fanconi anemia.

Shyamsunder P, Verma RS, Lyakhovich A.

Cancer Lett. 2015 May 28;361(1):33-8. doi: 10.1016/j.canlet.2015.02.020. Epub 2015 Feb 14.

PMID:
25687884
13.

Damaged mitochondria in Fanconi anemia - an isolated event or a general phenomenon?

Pagano G, Shyamsunder P, Verma RS, Lyakhovich A.

Oncoscience. 2014 Apr 21;1(4):287-95. eCollection 2014.

14.

IL-6, IL-8, MMP-2, MMP-9 are overexpressed in Fanconi anemia cells through a NF-κB/TNF-α dependent mechanism.

Epanchintsev A, Shyamsunder P, Verma RS, Lyakhovich A.

Mol Carcinog. 2015 Dec;54(12):1686-99. doi: 10.1002/mc.22240. Epub 2014 Oct 30.

PMID:
25358651
15.

Modulation of N-glycosylation by mesalamine facilitates membranous E-cadherin expression in colon epithelial cells.

Khare V, Lang M, Dammann K, Campregher C, Lyakhovich A, Gasche C.

Biochem Pharmacol. 2014 Jan 15;87(2):312-20. doi: 10.1016/j.bcp.2013.10.021. Epub 2013 Oct 30.

16.

Evidence of mitochondrial dysfunction and impaired ROS detoxifying machinery in Fanconi anemia cells.

Kumari U, Ya Jun W, Huat Bay B, Lyakhovich A.

Oncogene. 2014 Jan 9;33(2):165-72. doi: 10.1038/onc.2012.583. Epub 2013 Jan 14.

PMID:
23318445
17.

Damaged mitochondria and overproduction of ROS in Fanconi anemia cells.

Lyakhovich A.

Rare Dis. 2013 Feb 20;1:e24048. doi: 10.4161/rdis.24048. eCollection 2013.

18.

Mesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1.

Khare V, Lyakhovich A, Dammann K, Lang M, Borgmann M, Tichy B, Pospisilova S, Luciani G, Campregher C, Evstatiev R, Pflueger M, Hundsberger H, Gasche C.

Biochem Pharmacol. 2013 Jan 15;85(2):234-44. doi: 10.1016/j.bcp.2012.10.026. Epub 2012 Nov 9.

19.

Fanconi anemia protein FANCD2 inhibits TRF1 polyADP-ribosylation through tankyrase1-dependent manner.

Lyakhovich A, Ramirez MJ, Castellanos A, Castella M, Simons AM, Parvin JD, Surralles J.

Genome Integr. 2011 Feb 12;2(1):4. doi: 10.1186/2041-9414-2-4.

20.

Interaction of mesalasine (5-ASA) with translational initiation factors eIF4 partially explains 5-ASA anti-inflammatory and anti-neoplastic activities.

Lyakhovich A, Michlmayr A, Bakulina A, Gerner C, Oehler R, Gasche C.

Med Chem. 2011 Mar;7(2):92-8.

PMID:
21222616
21.

Constitutive activation of caspase-3 and Poly ADP ribose polymerase cleavage in fanconi anemia cells.

Lyakhovich A, Surrallés J.

Mol Cancer Res. 2010 Jan;8(1):46-56. doi: 10.1158/1541-7786.MCR-09-0373. Epub 2010 Jan 12.

22.

Systematic review: molecular chemoprevention of colorectal malignancy by mesalazine.

Lyakhovich A, Gasche C.

Aliment Pharmacol Ther. 2010 Jan 15;31(2):202-9. doi: 10.1111/j.1365-2036.2009.04195.x. Epub 2009 Nov 5. Review.

23.

The position of the amino group on the benzene ring is critical for mesalamine's improvement of replication fidelity.

Campregher C, Luciani MG, Biesenbach P, Evstatiev R, Lyakhovich A, Gasche C.

Inflamm Bowel Dis. 2010 Apr;16(4):576-82. doi: 10.1002/ibd.21112.

PMID:
19821510
24.

Quick two-dimensional differential in gel electrophoresis-based method to determine length and secondary structures of telomeric DNA.

Lyakhovich A, Bech-Serra JJ, Canals F, Surralles J.

Anal Biochem. 2009 Jan 15;384(2):356-8. doi: 10.1016/j.ab.2008.09.046. Epub 2008 Oct 5.

PMID:
18938127
25.

FANCD2 depletion sensitizes cancer cells repopulation ability in vitro.

Lyakhovich A, Surralles J.

Cancer Lett. 2007 Oct 28;256(2):186-95. Epub 2007 Jul 23.

PMID:
17643815
26.

New roads to FA/BRCA pathway: H2AX.

Lyakhovich A, Surrallés J.

Cell Cycle. 2007 May 2;6(9):1019-23. Epub 2007 May 1.

PMID:
17471025
27.

A DIGE-based approach to study interacting proteins.

Lyakhovich A, Canals F, Nosov M, Surralles J.

J Biochem Biophys Methods. 2007 Jun 10;70(4):693-5. Epub 2007 Mar 14.

PMID:
17433449
28.

Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability.

Bogliolo M, Lyakhovich A, Callén E, Castellà M, Cappelli E, Ramírez MJ, Creus A, Marcos R, Kalb R, Neveling K, Schindler D, Surrallés J.

EMBO J. 2007 Mar 7;26(5):1340-51. Epub 2007 Feb 15.

29.

Disruption of the Fanconi anemia/BRCA pathway in sporadic cancer.

Lyakhovich A, Surralles J.

Cancer Lett. 2006 Jan 28;232(1):99-106. Epub 2005 Oct 21. Review.

PMID:
16246487
31.
32.

Rad6 overexpression induces multinucleation, centrosome amplification, abnormal mitosis, aneuploidy, and transformation.

Shekhar MP, Lyakhovich A, Visscher DW, Heng H, Kondrat N.

Cancer Res. 2002 Apr 1;62(7):2115-24.

33.

Vitamin D and prostate cancer.

Tuohimaa P, Lyakhovich A, Aksenov N, Pennanen P, Syvälä H, Lou YR, Ahonen M, Hasan T, Pasanen P, Bläuer M, Manninen T, Miettinen S, Vilja P, Ylikomi T.

J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):125-34.

PMID:
11384870
34.

Vitamin D induced up-regulation of keratinocyte growth factor (FGF-7/KGF) in MCF-7 human breast cancer cells.

Lyakhovich A, Aksenov N, Pennanen P, Miettinen S, Ahonen MH, Syvälä H, Ylikomi T, Tuohimaa P.

Biochem Biophys Res Commun. 2000 Jul 5;273(2):675-80.

PMID:
10873663
35.

The socialist countries collaboration for the environment hygiene.

Sidorenko GI, Litvinov NN, Rakhmanina NA, Lyakhovich AV.

Sante Publique (Bucur). 1980;23(2):63-72. No abstract available.

PMID:
7209742

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