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Items: 20


T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis.

Cataisson C, Salcedo R, Michalowski AM, Klosterman M, Naik S, Li L, Pan MJ, Sweet A, Chen JQ, Kostecka LG, Karwan M, Smith L, Dai RM, Stewart CA, Lyakh L, Hsieh WT, Khan A, Yang H, Lee M, Trinchieri G, Yuspa SH.

Mol Cancer Res. 2019 Aug;17(8):1759-1773. doi: 10.1158/1541-7786.MCR-19-0227. Epub 2019 Jun 4.


Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation.

Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, Goldszmid R, McVicar DW, Lyakh L, Trinchieri G.

PLoS One. 2014 Dec 4;9(12):e114516. doi: 10.1371/journal.pone.0114516. eCollection 2014.


High expression of SNIP1 correlates with poor prognosis in non-small cell lung cancer and SNIP1 interferes with the recruitment of HDAC1 to RB in vitro.

Jeon HS, Choi YY, Fukuoka J, Fujii M, Lyakh LA, Song SH, Travis WD, Park JY, Jen J.

Lung Cancer. 2013 Oct;82(1):24-30. doi: 10.1016/j.lungcan.2013.07.015. Epub 2013 Aug 9.


LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells.

Orr SJ, Burg AR, Chan T, Quigley L, Jones GW, Ford JW, Hodge D, Razzook C, Sarhan J, Jones YL, Whittaker GC, Boelte KC, Lyakh L, Cardone M, O'Connor GM, Tan C, Li H, Anderson SK, Jones SA, Zhang W, Taylor PR, Trinchieri G, McVicar DW.

PLoS Pathog. 2013 May;9(5):e1003357. doi: 10.1371/journal.ppat.1003357. Epub 2013 May 9.


IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis.

Cataisson C, Salcedo R, Hakim S, Moffitt BA, Wright L, Yi M, Stephens R, Dai RM, Lyakh L, Schenten D, Yuspa HS, Trinchieri G.

J Exp Med. 2012 Aug 27;209(9):1689-702. doi: 10.1084/jem.20101355. Epub 2012 Aug 20.


Interferon-γ links ultraviolet radiation to melanomagenesis in mice.

Zaidi MR, Davis S, Noonan FP, Graff-Cherry C, Hawley TS, Walker RL, Feigenbaum L, Fuchs E, Lyakh L, Young HA, Hornyak TJ, Arnheiter H, Trinchieri G, Meltzer PS, De Fabo EC, Merlino G.

Nature. 2011 Jan 27;469(7331):548-53. doi: 10.1038/nature09666. Epub 2011 Jan 19.


Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans.

Lyakh L, Trinchieri G, Provezza L, Carra G, Gerosa F.

Immunol Rev. 2008 Dec;226:112-31. doi: 10.1111/j.1600-065X.2008.00700.x. Review.


Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells.

Gerosa F, Baldani-Guerra B, Lyakh LA, Batoni G, Esin S, Winkler-Pickett RT, Consolaro MR, De Marchi M, Giachino D, Robbiano A, Astegiano M, Sambataro A, Kastelein RA, Carra G, Trinchieri G.

J Exp Med. 2008 Jun 9;205(6):1447-61. doi: 10.1084/jem.20071450. Epub 2008 May 19.


SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.

Fujii M, Lyakh LA, Bracken CP, Fukuoka J, Hayakawa M, Tsukiyama T, Soll SJ, Harris M, Rocha S, Roche KC, Tominaga SI, Jen J, Perkins ND, Lechleider RJ, Roberts AB.

Mol Cell. 2006 Dec 8;24(5):771-783. doi: 10.1016/j.molcel.2006.11.006.


Role of Smad3 in the hormonal modulation of in vivo wound healing responses.

Ashcroft GS, Mills SJ, Flanders KC, Lyakh LA, Anzano MA, Gilliver SC, Roberts AB.

Wound Repair Regen. 2003 Nov-Dec;11(6):468-73.


Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cells.

Gasparian AV, Yao YJ, Lü J, Yemelyanov AY, Lyakh LA, Slaga TJ, Budunova IV.

Mol Cancer Ther. 2002 Oct;1(12):1079-87.


Levels of phospho-Smad2/3 are sensors of the interplay between effects of TGF-beta and retinoic acid on monocytic and granulocytic differentiation of HL-60 cells.

Cao Z, Flanders KC, Bertolette D, Lyakh LA, Wurthner JU, Parks WT, Letterio JJ, Ruscetti FW, Roberts AB.

Blood. 2003 Jan 15;101(2):498-507. Epub 2002 Sep 12.


The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells.

Gasparian AV, Yao YJ, Kowalczyk D, Lyakh LA, Karseladze A, Slaga TJ, Budunova IV.

J Cell Sci. 2002 Jan 1;115(Pt 1):141-51.


Adenovirus type 5 vectors induce dendritic cell differentiation in human CD14(+) monocytes cultured under serum-free conditions.

Lyakh LA, Koski GK, Young HA, Spence SE, Cohen PA, Rice NR.

Blood. 2002 Jan 15;99(2):600-8.


CD14+ monocytes as dendritic cell precursors: diverse maturation-inducing pathways lead to common activation of NF-kappab/RelB.

Koski GK, Lyakh LA, Cohen PA, Rice NR.

Crit Rev Immunol. 2001;21(1-3):179-89. Review.


Expression of NFAT-family proteins in normal human T cells.

Lyakh L, Ghosh P, Rice NR.

Mol Cell Biol. 1997 May;17(5):2475-84.


Type D retrovirus markers in healthy Africans from Guinea.

Morozov VA, Lagaye S, Lyakh L, ter Meulen J.

Res Virol. 1996 Nov-Dec;147(6):341-51.


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