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Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children.

Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF Jr, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD; National Heart, Lung, and Blood Institute's AsthmaNet.

J Allergy Clin Immunol. 2019 Jan 17. pii: S0091-6749(19)30032-6. doi: 10.1016/j.jaci.2018.10.071. [Epub ahead of print] No abstract available.


Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program.

Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG.

J Allergy Clin Immunol. 2019 Jan 8. pii: S0091-6749(18)31732-9. doi: 10.1016/j.jaci.2018.11.022. [Epub ahead of print]


Nanostars on Nanopipette Tips: A Raman Probe for Quantifying Oxygen Levels in Hypoxic Single Cells and Tumours.

Nguyen TD, Song MS, Ly NH, Lee SY, Joo SW.

Angew Chem Int Ed Engl. 2019 Feb 25;58(9):2710-2714. doi: 10.1002/anie.201812677. Epub 2019 Feb 1.


Humanised effector-null FcγRIIA antibody inhibits immune complex-mediated proinflammatory responses.

Chen B, Vousden KA, Naiman B, Turman S, Sun H, Wang S, Vinall LMK, Kemp BP, Kasturiangan S, Rees DG, Grant E, Hinrichs MJ, Eck S, DiGiandomenico A, Jack Borrok M, Ly N, Xiong X, Gonzalez C, Morehouse C, Wang Y, Zhou Y, Cann J, Zhao W, Koelkebeck H, Okubo K, Mayadas TN, Howe D, Griffiths J, Kolbeck R, Herbst R, Sims GP.

Ann Rheum Dis. 2019 Feb;78(2):228-237. doi: 10.1136/annrheumdis-2018-213523. Epub 2018 Nov 20.


Telomere shortening by transgenerational transmission of TNF-α-induced TERRA via ATF7.

Liu B, Maekawa T, Yoshida K, Ly NH, Inoue K, Hasegawa A, Chatton B, Ogura A, Ishii S.

Nucleic Acids Res. 2019 Jan 10;47(1):283-298. doi: 10.1093/nar/gky1149.


Palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus: possible involvement of CD163+ M2 macrophages in two cases, and a review of published works.

Terai S, Ueda-Hayakawa I, Nguyen CTH, Ly NTM, Yamazaki F, Kambe N, Son Y, Okamoto H.

Lupus. 2018 Dec;27(14):2220-2227. doi: 10.1177/0961203318809892. Epub 2018 Oct 30. Review.


Biopharmaceutical Industry Approaches to Facility Segregation for Viral Safety: An Effort from the Consortium on Adventitious Agent Contamination in Biomanufacturing.

Barone PW, Avgerinos S, Ballard R, Brussel A, Clark P, Dowd C, Gerentes L, Hart I, Keumurian FJ, Kindermann J, Leung JC, Ly N, Mink S, Minning S, Mülberg J, Murphy M, Nöske K, Parriott S, Shum B, Wiebe ME, Springs SL.

PDA J Pharm Sci Technol. 2018 Oct 25. pii: pdajpst.2018.008862. doi: 10.5731/pdajpst.2018.008862. [Epub ahead of print]


Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children.

Zinter MS, Dvorak CC, Mayday MY, Iwanaga K, Ly NP, McGarry ME, Church GD, Faricy LE, Rowan CM, Hume JR, Steiner ME, Crawford ED, Langelier C, Kalantar K, Chow ED, Miller S, Shimano K, Melton A, Yanik GA, Sapru A, DeRisi JL.

Clin Infect Dis. 2018 Sep 15. doi: 10.1093/cid/ciy802. [Epub ahead of print]


Frustrated endocytosis controls contractility-independent mechanotransduction at clathrin-coated structures.

Baschieri F, Dayot S, Elkhatib N, Ly N, Capmany A, Schauer K, Betz T, Vignjevic DM, Poincloux R, Montagnac G.

Nat Commun. 2018 Sep 20;9(1):3825. doi: 10.1038/s41467-018-06367-y.


Unique Energy Transfer in Fluorescein-Conjugated Au22 Nanoclusters Leading to 160-Fold pH-Contrasting Photoluminescence.

Pyo K, Ly NH, Han SM, Hatshan MB, Abuhagr A, Wiederrecht G, Joo SW, Ramakrishna G, Lee D.

J Phys Chem Lett. 2018 Sep 20;9(18):5303-5310. doi: 10.1021/acs.jpclett.8b02130. Epub 2018 Sep 5.


Raman spectroscopy of pH-induced release of zidovudine from lactobionic acid-conjugated PEGylated gold colloids.

Ly NH, Nguyen TD, Joo SW.

Colloids Surf B Biointerfaces. 2018 Nov 1;171:49-57. doi: 10.1016/j.colsurfb.2018.05.042. Epub 2018 May 19.


Immune Checkpoint Blockade Restores HIV-Specific CD4 T Cell Help for NK Cells.

Porichis F, Hart MG, Massa A, Everett HL, Morou A, Richard J, Brassard N, Veillette M, Hassan M, Ly NL, Routy JP, Freeman GJ, Dubé M, Finzi A, Kaufmann DE.

J Immunol. 2018 Aug 1;201(3):971-981. doi: 10.4049/jimmunol.1701551. Epub 2018 Jun 22.


On-site detection of sub-mg/kg melamine mixed in powdered infant formula and chocolate using sharp-edged gold nanostar substrates.

Nguyen TH, Nguyen TD, Ly NH, Kwak CH, Huh YS, Joo SW.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Jun;35(6):1017-1026. doi: 10.1080/19440049.2018.1466399. Epub 2018 Jun 1.


Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma.

DeBoer MD, Phillips BR, Mauger DT, Zein J, Erzurum SC, Fitzpatrick AM, Gaston BM, Myers R, Ross KR, Chmiel J, Lee MJ, Fahy JV, Peters M, Ly NP, Wenzel SE, Fajt ML, Holguin F, Moore WC, Peters SP, Meyers D, Bleecker ER, Castro M, Coverstone AM, Bacharier LB, Jarjour NN, Sorkness RL, Ramratnam S, Irani AM, Israel E, Levy B, Phipatanakul W, Gaffin JM, Gerald Teague W.

BMC Pulm Med. 2018 Apr 10;18(1):58. doi: 10.1186/s12890-018-0612-x.


TARC expression in the circulation and cutaneous granulomas correlates with disease severity and indicates Th2-mediated progression in patients with sarcoidosis.

Nguyen CTH, Kambe N, Ueda-Hayakawa I, Kishimoto I, Ly NTM, Mizuno K, Okamoto H.

Allergol Int. 2018 Oct;67(4):487-495. doi: 10.1016/j.alit.2018.02.011. Epub 2018 Mar 26.


Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations.

Jackson DJ, Bacharier LB, Mauger DT, Boehmer S, Beigelman A, Chmiel JF, Fitzpatrick AM, Gaffin JM, Morgan WJ, Peters SP, Phipatanakul W, Sheehan WJ, Cabana MD, Holguin F, Martinez FD, Pongracic JA, Baxi SN, Benson M, Blake K, Covar R, Gentile DA, Israel E, Krishnan JA, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Long D, Ly N, Marbin J, Moy JN, Myers RE, Olin JT, Raissy HH, Robison RG, Ross K, Sorkness CA, Lemanske RF Jr; National Heart, Lung, and Blood Institute AsthmaNet.

N Engl J Med. 2018 Mar 8;378(10):891-901. doi: 10.1056/NEJMoa1710988. Epub 2018 Mar 3.


Proximal tubular epithelial cells preferentially endocytose covalently-modified albumin compared to native albumin.

Ly ND, Tesch GH, Nikolic-Paterson DJ, Poronnik P.

Nephrology (Carlton). 2019 Jan;24(1):121-126. doi: 10.1111/nep.13211.


Early cutaneous eruptions after oral hydroxychloroquine in a lupus erythematosus patient: A case report and review of the published work.

Matsuda T, Ly NTM, Kambe N, Nguyen CTH, Ueda-Hayakawa I, Son Y, Okamoto H.

J Dermatol. 2018 Mar;45(3):344-348. doi: 10.1111/1346-8138.14156. Epub 2017 Dec 14. Review.


Interaction between Diethyldithiocarbamate and Cu(II) on Gold in Non-Cyanide Wastewater.

Ly NH, Nguyen TD, Zoh KD, Joo SW.

Sensors (Basel). 2017 Nov 15;17(11). pii: E2628. doi: 10.3390/s17112628.


Reduced tubular degradation of glomerular filtered plasma albumin is a common feature in acute and chronic kidney disease.

Han Y, Ly NDK, Tesch GH, Poronnik P, Nikolic-Paterson DJ.

Clin Exp Pharmacol Physiol. 2018 Mar;45(3):241-249. doi: 10.1111/1440-1681.12878. Epub 2017 Nov 28.


Pulmonary function disparities exist and persist in Hispanic patients with cystic fibrosis: A longitudinal analysis.

McGarry ME, Neuhaus JM, Nielson DW, Burchard E, Ly NP.

Pediatr Pulmonol. 2017 Dec;52(12):1550-1557. doi: 10.1002/ppul.23884. Epub 2017 Oct 30.


Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age.

Teague WG, Phillips BR, Fahy JV, Wenzel SE, Fitzpatrick AM, Moore WC, Hastie AT, Bleecker ER, Meyers DA, Peters SP, Castro M, Coverstone AM, Bacharier LB, Ly NP, Peters MC, Denlinger LC, Ramratnam S, Sorkness RL, Gaston BM, Erzurum SC, Comhair SAA, Myers RE, Zein J, DeBoer MD, Irani AM, Israel E, Levy B, Cardet JC, Phipatanakul W, Gaffin JM, Holguin F, Fajt ML, Aujla SJ, Mauger DT, Jarjour NN.

J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):545-554.e4. doi: 10.1016/j.jaip.2017.05.032. Epub 2017 Aug 31.


The unique C terminus of the calcineurin isoform CNAβ1 confers non-canonical regulation of enzyme activity by Ca2+ and calmodulin.

Bond R, Ly N, Cyert MS.

J Biol Chem. 2017 Oct 6;292(40):16709-16721. doi: 10.1074/jbc.M117.795146. Epub 2017 Aug 25.


Short-term outcomes following cytoreductive surgery and heated intra-peritoneal chemotherapy at Waikato.

Ly NJ, Wu L, Dalen RV, Lolohea S.

N Z Med J. 2017 Jul 21;130(1459):33-42.


Highly Luminescent Folate-Functionalized Au22 Nanoclusters for Bioimaging.

Pyo K, Ly NH, Yoon SY, Shen Y, Choi SY, Lee SY, Joo SW, Lee D.

Adv Healthc Mater. 2017 Aug;6(16). doi: 10.1002/adhm.201700203. Epub 2017 May 15.


Silica-encapsulated gold nanoparticle dimers for organelle-targeted cellular delivery.

Cong VT, Ly NH, Son SJ, Min J, Joo SW.

Chem Commun (Camb). 2017 May 2;53(36):5009-5012. doi: 10.1039/c7cc01229b.


Epigenetic modification of glucocorticoid receptor promoter I7 in maternally separated and restraint-stressed rats.

Park SW, Lee JG, Seo MK, Ly NN, Lee CH, Cho HY, Hein LT, Choi AJ, Kim GM, Kim YH.

Neurosci Lett. 2017 May 22;650:38-44. doi: 10.1016/j.neulet.2017.04.024. Epub 2017 Apr 13.


One-Step Ligand Immobilization and Single Sample Injection for Regeneration-Free Surface Plasmon Resonance Measurements of Biomolecular Interactions.

Wang X, Li Z, Ly N, Zhou F.

Anal Chem. 2017 Mar 21;89(6):3261-3265. doi: 10.1021/acs.analchem.7b00121. Epub 2017 Mar 3.


Radiotherapy after Sentinel Lymph Node Biopsy (SLNB) using SIENNA+®, super paramagnetic iron oxide particles (SPIO): Prospective study of tolerance and toxicity.

Kirova YM, Chilles A, Ly N, Tardivon A, Alran S.

Radiother Oncol. 2017 Mar;122(3):485. doi: 10.1016/j.radonc.2017.01.011. Epub 2017 Feb 10. No abstract available.


A 6-Month-Old Infant With Different Capnography Values in Polysomnography.

DelRosso LM, Palacay P, Ly NP.

Chest. 2017 Feb;151(2):e45-e48. doi: 10.1016/j.chest.2016.08.1463.


Influence of rhlR and lasR on Polymyxin Pharmacodynamics in Pseudomonas aeruginosa and Implications for Quorum Sensing Inhibition with Azithromycin.

Bulman ZP, Ly NS, Lenhard JR, Holden PN, Bulitta JB, Tsuji BT.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e00096-16. doi: 10.1128/AAC.00096-16. Print 2017 Apr.


Calcineurin, the Ca2+-dependent phosphatase, regulates Rga2, a Cdc42 GTPase-activating protein, to modulate pheromone signaling.

Ly N, Cyert MS.

Mol Biol Cell. 2017 Mar 1;28(5):576-586. doi: 10.1091/mbc.E16-06-0432. Epub 2017 Jan 11.


In vivo and in vitro ivacaftor response in cystic fibrosis patients with residual CFTR function: N-of-1 studies.

McGarry ME, Illek B, Ly NP, Zlock L, Olshansky S, Moreno C, Finkbeiner WE, Nielson DW.

Pediatr Pulmonol. 2017 Apr;52(4):472-479. doi: 10.1002/ppul.23659. Epub 2017 Jan 9.


Polymyxin B in combination with meropenem against carbapenemase-producing Klebsiella pneumoniae: pharmacodynamics and morphological changes.

Sharma R, Patel S, Abboud C, Diep J, Ly NS, Pogue JM, Kaye KS, Li J, Rao GG.

Int J Antimicrob Agents. 2017 Feb;49(2):224-232. doi: 10.1016/j.ijantimicag.2016.10.025. Epub 2016 Dec 23.


Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma.

Phipatanakul W, Mauger DT, Sorkness RL, Gaffin JM, Holguin F, Woodruff PG, Ly NP, Bacharier LB, Bhakta NR, Moore WC, Bleecker ER, Hastie AT, Meyers DA, Castro M, Fahy JV, Fitzpatrick AM, Gaston BM, Jarjour NN, Levy BD, Peters SP, Teague WG, Fajt M, Wenzel SE, Erzurum SC, Israel E; Severe Asthma Research Program.

Am J Respir Crit Care Med. 2017 Jun 1;195(11):1439-1448. doi: 10.1164/rccm.201607-1453OC.


Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery.

Wittau M, Paschke S, Kurlbaum M, Scheele J, Ly NS, Hemper E, Kornmann M, Henne-Bruns D, Bulitta JB.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e00952-16. doi: 10.1128/AAC.00952-16. Print 2017 Jan.


Biophysical characterization of soluble Pseudomonas syringae ice nucleation protein InaZ fragments.

Han YJ, Song H, Lee CW, Ly NH, Joo SW, Lee JH, Kim SJ, Park S.

Int J Biol Macromol. 2017 Jan;94(Pt A):634-641. doi: 10.1016/j.ijbiomac.2016.10.062. Epub 2016 Oct 20.


Individualized therapy for persistent asthma in young children.

Fitzpatrick AM, Jackson DJ, Mauger DT, Boehmer SJ, Phipatanakul W, Sheehan WJ, Moy JN, Paul IM, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan W, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Szefler SJ; NIH/NHLBI AsthmaNet.

J Allergy Clin Immunol. 2016 Dec;138(6):1608-1618.e12. doi: 10.1016/j.jaci.2016.09.028. Epub 2016 Oct 21.


αTAT1 controls longitudinal spreading of acetylation marks from open microtubules extremities.

Ly N, Elkhatib N, Bresteau E, Piétrement O, Khaled M, Magiera MM, Janke C, Le Cam E, Rutenberg AD, Montagnac G.

Sci Rep. 2016 Oct 18;6:35624. doi: 10.1038/srep35624.


Luminescent properties of 4-aminobenzo-15-crown-5 after preferential binding of ferric ions in aqueous solutions.

Ly NH, Yoon J, Nguyen DB, Cho KH, Joo SW.

Luminescence. 2017 Jun;32(4):549-554. doi: 10.1002/bio.3220. Epub 2016 Oct 12.


Severe Postictal Hypoxemia-Associated Seizure in a 12-Year-Old Child.

DelRosso LM, Hoque R, Mitchell C, Ly NP.

J Clin Sleep Med. 2016 Dec 15;12(12):1691-1693. doi: 10.5664/jcsm.6360.


RNA sequence analyses of r-Moj-DM treated cells: TXNIP is required to induce apoptosis of SK-Mel-28.

McBride TD, Andrew U, Ly N, Soto JG.

Toxicon. 2016 Oct;121:1-9. doi: 10.1016/j.toxicon.2016.08.014. Epub 2016 Aug 24.


Account for all medications, even if they're banned.

Ly N.

J Fam Pract. 2016 Jul;65(7):437. No abstract available.


Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations.

Denlinger LC, Phillips BR, Ramratnam S, Ross K, Bhakta NR, Cardet JC, Castro M, Peters SP, Phipatanakul W, Aujla S, Bacharier LB, Bleecker ER, Comhair SA, Coverstone A, DeBoer M, Erzurum SC, Fain SB, Fajt M, Fitzpatrick AM, Gaffin J, Gaston B, Hastie AT, Hawkins GA, Holguin F, Irani AM, Israel E, Levy BD, Ly N, Meyers DA, Moore WC, Myers R, Opina MT, Peters MC, Schiebler ML, Sorkness RL, Teague WG, Wenzel SE, Woodruff PG, Mauger DT, Fahy JV, Jarjour NN; National Heart, Lung, and Blood Institute’s Severe Asthma Research Program-3 Investigators.

Am J Respir Crit Care Med. 2017 Feb 1;195(3):302-313. doi: 10.1164/rccm.201602-0419OC.


Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma.

Sheehan WJ, Mauger DT, Paul IM, Moy JN, Boehmer SJ, Szefler SJ, Fitzpatrick AM, Jackson DJ, Bacharier LB, Cabana MD, Covar R, Holguin F, Lemanske RF Jr, Martinez FD, Pongracic JA, Beigelman A, Baxi SN, Benson M, Blake K, Chmiel JF, Daines CL, Daines MO, Gaffin JM, Gentile DA, Gower WA, Israel E, Kumar HV, Lang JE, Lazarus SC, Lima JJ, Ly N, Marbin J, Morgan WJ, Myers RE, Olin JT, Peters SP, Raissy HH, Robison RG, Ross K, Sorkness CA, Thyne SM, Wechsler ME, Phipatanakul W; NIH/NHLBI AsthmaNet.

N Engl J Med. 2016 Aug 18;375(7):619-30. doi: 10.1056/NEJMoa1515990.


Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies.

Rao GG, Ly NS, Bulitta JB, Soon RL, San Roman MD, Holden PN, Landersdorfer CB, Nation RL, Li J, Forrest A, Tsuji BT.

J Antimicrob Chemother. 2016 Nov;71(11):3148-3156. Epub 2016 Aug 3.


Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii.

Rao GG, Ly NS, Diep J, Forrest A, Bulitta JB, Holden PN, Nation RL, Li J, Tsuji BT.

Int J Antimicrob Agents. 2016 Sep;48(3):331-6. doi: 10.1016/j.ijantimicag.2016.06.006. Epub 2016 Jul 12.


A 16-Year-Old Boy with Refractory Epilepsy and Sleep-Disordered Breathing.

DelRosso LM, Hoque R, Contreras MB, Ly NP.

J Clin Sleep Med. 2016 Jul 15;12(7):1062-4. doi: 10.5664/jcsm.5952. No abstract available.


Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome.

Hencken L, To L, Ly N, Morgan JA.

J Card Surg. 2016 Apr;31(4):208-10. doi: 10.1111/jocs.12705. Epub 2016 Mar 2.


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