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Items: 42


"Nine Dimensions": A multidisciplinary approach for community engagement in a complex postwar border region as part of the targeted malaria elimination in Karen/Kayin State, Myanmar.

Tangseefa D, Monthathip K, Tuenpakdee N, König A, Kajeechiwa L, Thwin MM, Nosten S, Tun SW, Ma K, Hashmi A, Lwin KM, Cheah PY, von Seidlein L, Nosten F.

Version 2. Wellcome Open Res. 2019 Feb 21 [revised 2019 Jan 1];3:116. doi: 10.12688/wellcomeopenres.14698.2. eCollection 2018.


The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial.

von Seidlein L, Peto TJ, Landier J, Nguyen TN, Tripura R, Phommasone K, Pongvongsa T, Lwin KM, Keereecharoen L, Kajeechiwa L, Thwin MM, Parker DM, Wiladphaingern J, Nosten S, Proux S, Corbel V, Tuong-Vy N, Phuc-Nhi TL, Son DH, Huong-Thu PN, Tuyen NTK, Tien NT, Dong LT, Hue DV, Quang HH, Nguon C, Davoeung C, Rekol H, Adhikari B, Henriques G, Phongmany P, Suangkanarat P, Jeeyapant A, Vihokhern B, van der Pluijm RW, Lubell Y, White LJ, Aguas R, Promnarate C, Sirithiranont P, Malleret B, Rénia L, Onsjö C, Chan XH, Chalk J, Miotto O, Patumrat K, Chotivanich K, Hanboonkunupakarn B, Jittmala P, Kaehler N, Cheah PY, Pell C, Dhorda M, Imwong M, Snounou G, Mukaka M, Peerawaranun P, Lee SJ, Simpson JA, Pukrittayakamee S, Singhasivanon P, Grobusch MP, Cobelens F, Smithuis F, Newton PN, Thwaites GE, Day NPJ, Mayxay M, Hien TT, Nosten FH, Dondorp AM, White NJ.

PLoS Med. 2019 Feb 15;16(2):e1002745. doi: 10.1371/journal.pmed.1002745. eCollection 2019 Feb.


Operational Performance of a Plasmodium falciparum Ultrasensitive Rapid Diagnostic Test for Detection of Asymptomatic Infections in Eastern Myanmar.

Landier J, Haohankhunnatham W, Das S, Konghahong K, Christensen P, Raksuansak J, Phattharakokoedbun P, Kajeechiwa L, Thwin MM, Jang IK, Imwong M, Wiladphaingern J, Lwin KM, Ling C, Proux S, Domingo GJ, Delmas G, Nosten FH.

J Clin Microbiol. 2018 Jul 26;56(8). pii: e00565-18. doi: 10.1128/JCM.00565-18. Print 2018 Aug.


Comparison of the Cumulative Efficacy and Safety of Chloroquine, Artesunate, and Chloroquine-Primaquine in Plasmodium vivax Malaria.

Chu CS, Phyo AP, Lwin KM, Win HH, San T, Aung AA, Raksapraidee R, Carrara VI, Bancone G, Watson J, Moore KA, Wiladphaingern J, Proux S, Sriprawat K, Winterberg M, Cheah PY, Chue AL, Tarning J, Imwong M, Nosten F, White NJ.

Clin Infect Dis. 2018 Oct 30;67(10):1543-1549. doi: 10.1093/cid/ciy319.


Chromosomal breaks at FRA18C: association with reduced DOK6 expression, altered oncogenic signaling and increased gastric cancer survival.

Leong SH, Lwin KM, Lee SS, Ng WH, Ng KM, Tan SY, Ng BL, Carter NP, Tang C, Lian Kon O.

NPJ Precis Oncol. 2017 May 1;1(1):9. doi: 10.1038/s41698-017-0012-3. eCollection 2017.


Effect of generalised access to early diagnosis and treatment and targeted mass drug administration on Plasmodium falciparum malaria in Eastern Myanmar: an observational study of a regional elimination programme.

Landier J, Parker DM, Thu AM, Lwin KM, Delmas G, Nosten FH; Malaria Elimination Task Force Group.

Lancet. 2018 May 12;391(10133):1916-1926. doi: 10.1016/S0140-6736(18)30792-X. Epub 2018 Apr 24.


Scale up of a Plasmodium falciparum elimination program and surveillance system in Kayin State, Myanmar.

Parker DM, Landier J, Thu AM, Lwin KM, Delmas G, Nosten FH; Malaria Elimination Task Force Group.

Wellcome Open Res. 2017 Dec 22;2:98. doi: 10.12688/wellcomeopenres.12741.2. eCollection 2017.


Population Pharmacokinetic Properties of Piperaquine in Falciparum Malaria: An Individual Participant Data Meta-Analysis.

Hoglund RM, Workman L, Edstein MD, Thanh NX, Quang NN, Zongo I, Ouedraogo JB, Borrmann S, Mwai L, Nsanzabana C, Price RN, Dahal P, Sambol NC, Parikh S, Nosten F, Ashley EA, Phyo AP, Lwin KM, McGready R, Day NP, Guerin PJ, White NJ, Barnes KI, Tarning J.

PLoS Med. 2017 Jan 10;14(1):e1002212. doi: 10.1371/journal.pmed.1002212. eCollection 2017 Jan.


GhABF2, a bZIP transcription factor, confers drought and salinity tolerance in cotton (Gossypium hirsutum L.).

Liang C, Meng Z, Meng Z, Malik W, Yan R, Lwin KM, Lin F, Wang Y, Sun G, Zhou T, Zhu T, Li J, Jin S, Guo S, Zhang R.

Sci Rep. 2016 Oct 7;6:35040. doi: 10.1038/srep35040.


The role of early detection and treatment in malaria elimination.

Landier J, Parker DM, Thu AM, Carrara VI, Lwin KM, Bonnington CA, Pukrittayakamee S, Delmas G, Nosten FH.

Malar J. 2016 Jul 15;15:363. doi: 10.1186/s12936-016-1399-y. Review.


Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai-Myanmar Border (2003-2013): The Role of Parasite Genetic Factors.

Phyo AP, Ashley EA, Anderson TJC, Bozdech Z, Carrara VI, Sriprawat K, Nair S, White MM, Dziekan J, Ling C, Proux S, Konghahong K, Jeeyapant A, Woodrow CJ, Imwong M, McGready R, Lwin KM, Day NPJ, White NJ, Nosten F.

Clin Infect Dis. 2016 Sep 15;63(6):784-791. doi: 10.1093/cid/ciw388. Epub 2016 Jun 16.


Kinesin-related Smy1 enhances the Rab-dependent association of myosin-V with secretory cargo.

Lwin KM, Li D, Bretscher A.

Mol Biol Cell. 2016 Aug 1;27(15):2450-62. doi: 10.1091/mbc.E16-03-0185. Epub 2016 Jun 15.


Numerical Distributions of Parasite Densities During Asymptomatic Malaria.

Imwong M, Stepniewska K, Tripura R, Peto TJ, Lwin KM, Vihokhern B, Wongsaen K, von Seidlein L, Dhorda M, Snounou G, Keereecharoen L, Singhasivanon P, Sirithiranont P, Chalk J, Nguon C, Day NP, Nosten F, Dondorp A, White NJ.

J Infect Dis. 2016 Apr 15;213(8):1322-9. doi: 10.1093/infdis/jiv596. Epub 2015 Dec 17.


The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam.

Imwong M, Nguyen TN, Tripura R, Peto TJ, Lee SJ, Lwin KM, Suangkanarat P, Jeeyapant A, Vihokhern B, Wongsaen K, Van Hue D, Dong le T, Nguyen TU, Lubell Y, von Seidlein L, Dhorda M, Promnarate C, Snounou G, Malleret B, Rénia L, Keereecharoen L, Singhasivanon P, Sirithiranont P, Chalk J, Nguon C, Hien TT, Day N, White NJ, Dondorp A, Nosten F.

Malar J. 2015 Sep 30;14:381. doi: 10.1186/s12936-015-0906-x.


Elimination of Plasmodium falciparum in an area of multi-drug resistance.

Lwin KM, Imwong M, Suangkanarat P, Jeeyapant A, Vihokhern B, Wongsaen K, Snounou G, Keereecharoen L, White NJ, Nosten F.

Malar J. 2015 Aug 16;14:319. doi: 10.1186/s12936-015-0838-5.


Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker.

Tun KM, Imwong M, Lwin KM, Win AA, Hlaing TM, Hlaing T, Lin K, Kyaw MP, Plewes K, Faiz MA, Dhorda M, Cheah PY, Pukrittayakamee S, Ashley EA, Anderson TJ, Nair S, McDew-White M, Flegg JA, Grist EP, Guerin P, Maude RJ, Smithuis F, Dondorp AM, Day NP, Nosten F, White NJ, Woodrow CJ.

Lancet Infect Dis. 2015 Apr;15(4):415-21. doi: 10.1016/S1473-3099(15)70032-0. Epub 2015 Feb 20.


Characterization of an in vivo concentration-effect relationship for piperaquine in malaria chemoprevention.

Bergstrand M, Nosten F, Lwin KM, Karlsson MO, White NJ, Tarning J.

Sci Transl Med. 2014 Oct 29;6(260):260ra147. doi: 10.1126/scitranslmed.3005311. Epub 2014 Oct 29.


Population Pharmacokinetics and Antimalarial Pharmacodynamics of Piperaquine in Patients With Plasmodium vivax Malaria in Thailand.

Tarning J, Thana P, Phyo AP, Lwin KM, Hanpithakpong W, Ashley EA, Day NP, Nosten F, White NJ.

CPT Pharmacometrics Syst Pharmacol. 2014 Aug 27;3:e132. doi: 10.1038/psp.2014.29.


Linking international clinical research with stateless populations to justice in global health.

Pratt B, Zion D, Lwin KM, Cheah PY, Nosten F, Loff B.

BMC Med Ethics. 2014 Jun 26;15:49. doi: 10.1186/1472-6939-15-49.


Population pharmacokinetic assessment of the effect of food on piperaquine bioavailability in patients with uncomplicated malaria.

Tarning J, Lindegardh N, Lwin KM, Annerberg A, Kiricharoen L, Ashley E, White NJ, Nosten F, Day NP.

Antimicrob Agents Chemother. 2014;58(4):2052-8. doi: 10.1128/AAC.02318-13. Epub 2014 Jan 21.


Ancillary Care: From Theory to Practice in International Clinical Research.

Pratt B, Zion D, Lwin KM, Cheah PY, Nosten F, Loff B.

Public Health Ethics. 2013 Jul;6(2):154-169. Epub 2013 Jun 13.


Exploitation and community engagement: can community advisory boards successfully assume a role minimising exploitation in international research?

Pratt B, Lwin KM, Zion D, Nosten F, Loff B, Cheah PY.

Dev World Bioeth. 2015 Apr;15(1):18-26. doi: 10.1111/dewb.12031. Epub 2013 May 31.


Triangular test design to evaluate tinidazole in the prevention of Plasmodium vivax relapse.

Macareo L, Lwin KM, Cheah PY, Yuentrakul P, Miller RS, Nosten F.

Malar J. 2013 May 29;12:173. doi: 10.1186/1475-2875-12-173.


Malaria burden and artemisinin resistance in the mobile and migrant population on the Thai-Myanmar border, 1999-2011: an observational study.

Carrara VI, Lwin KM, Phyo AP, Ashley E, Wiladphaingern J, Sriprawat K, Rijken M, Boel M, McGready R, Proux S, Chu C, Singhasivanon P, White N, Nosten F.

PLoS Med. 2013;10(3):e1001398. doi: 10.1371/journal.pmed.1001398. Epub 2013 Mar 5.


Effect of high-dose or split-dose artesunate on parasite clearance in artemisinin-resistant falciparum malaria.

Das D, Tripura R, Phyo AP, Lwin KM, Tarning J, Lee SJ, Hanpithakpong W, Stepniewska K, Menard D, Ringwald P, Silamut K, Imwong M, Chotivanich K, Yi P, Day NP, Lindegardh N, Socheat D, Nguon C, White NJ, Nosten F, Dondorp AM.

Clin Infect Dis. 2013 Mar;56(5):e48-58. doi: 10.1093/cid/cis958. Epub 2012 Nov 21.


Effect of early detection and treatment on malaria related maternal mortality on the north-western border of Thailand 1986-2010.

McGready R, Boel M, Rijken MJ, Ashley EA, Cho T, Moo O, Paw MK, Pimanpanarak M, Hkirijareon L, Carrara VI, Lwin KM, Phyo AP, Turner C, Chu CS, van Vugt M, Price RN, Luxemburger C, ter Kuile FO, Tan SO, Proux S, Singhasivanon P, White NJ, Nosten FH.

PLoS One. 2012;7(7):e40244. doi: 10.1371/journal.pone.0040244. Epub 2012 Jul 18.


Refugee and migrant women's views of antenatal ultrasound on the Thai Burmese border: a mixed methods study.

Rijken MJ, Gilder ME, Thwin MM, Ladda Kajeechewa HM, Wiladphaingern J, Lwin KM, Jones C, Nosten F, McGready R.

PLoS One. 2012;7(4):e34018. doi: 10.1371/journal.pone.0034018. Epub 2012 Apr 13.


A major genome region underlying artemisinin resistance in malaria.

Cheeseman IH, Miller BA, Nair S, Nkhoma S, Tan A, Tan JC, Al Saai S, Phyo AP, Moo CL, Lwin KM, McGready R, Ashley E, Imwong M, Stepniewska K, Yi P, Dondorp AM, Mayxay M, Newton PN, White NJ, Nosten F, Ferdig MT, Anderson TJ.

Science. 2012 Apr 6;336(6077):79-82. doi: 10.1126/science.1215966.


Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study.

Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, ler Moo C, Al-Saai S, Dondorp AM, Lwin KM, Singhasivanon P, Day NP, White NJ, Anderson TJ, Nosten F.

Lancet. 2012 May 26;379(9830):1960-6. doi: 10.1016/S0140-6736(12)60484-X. Epub 2012 Apr 5.


Closing the translation gap for justice requirements in international research.

Pratt B, Zion D, Lwin KM, Cheah PY, Nosten F, Loff B.

J Med Ethics. 2012 Sep;38(9):552-8. doi: 10.1136/medethics-2011-100301. Epub 2012 Mar 16.


Randomized, double-blind, placebo-controlled trial of monthly versus bimonthly dihydroartemisinin-piperaquine chemoprevention in adults at high risk of malaria.

Lwin KM, Phyo AP, Tarning J, Hanpithakpong W, Ashley EA, Lee SJ, Cheah P, Singhasivanon P, White NJ, Lindegårdh N, Nosten F.

Antimicrob Agents Chemother. 2012 Mar;56(3):1571-7. doi: 10.1128/AAC.05877-11. Epub 2012 Jan 17.


Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial.

Phyo AP, Lwin KM, Price RN, Ashley EA, Russell B, Sriprawat K, Lindegardh N, Singhasivanon P, White NJ, Nosten F.

Clin Infect Dis. 2011 Nov;53(10):977-84. doi: 10.1093/cid/cir631.


A small amount of fat does not affect piperaquine exposure in patients with malaria.

Annerberg A, Lwin KM, Lindegardh N, Khrutsawadchai S, Ashley E, Day NP, Singhasivanon P, Tarning J, White NJ, Nosten F.

Antimicrob Agents Chemother. 2011 Sep;55(9):3971-6. doi: 10.1128/AAC.00279-11. Epub 2011 Jun 27.


The presence of leukocytes in ex vivo assays significantly increases the 50-percent inhibitory concentrations of artesunate and chloroquine against Plasmodium vivax and Plasmodium falciparum.

Kaewpongsri S, Sriprawat K, Suwanarusk R, Kyle DE, Lek-Uthai U, Leimanis M, Lwin KM, Phyo AP, Zwang J, Russell B, Nosten F, Renia L.

Antimicrob Agents Chemother. 2011 Mar;55(3):1300-4. doi: 10.1128/AAC.01103-10. Epub 2010 Dec 28.


Surveillance of antibiotic resistance in Neisseria gonorrhoeae in the WHO Western Pacific and South East Asian regions, 2007-2008.

WHO Western Pacific Programme; South East Asian Gonococcal Antimicrobial Surveillance Programme, Tapsall JW, Limnios EA, Abu Bakar HM, Darussalam B, Ping YY, Buadromo EM, Kumar P, Singh S, Lo J, Bala M, Risbud A, Deguchi T, Tanaka M, Watanabe Y, Lee K, Chong Y, Noikaseumsy S, Phouthavane T, Sam IC, Tundev O, Lwin KM, Eh PH, Goarant C, Goursaud R, Bathgate T, Brokenshire M, Latorre L, Velemu E, Carlos C, Leano S, Telan EO, Goh SS, Koh ST, Ngan C, Tan AL, Mananwatte S, Piyanoot N, Lokpichat S, Sirivongranson P, Fakahau M, Sitanilei H, Hung le V.

Commun Dis Intell Q Rep. 2010 Mar;34(1):1-7.


Community engagement on the Thai-Burmese border: rationale, experience and lessons learnt.

Cheah PY, Lwin KM, Phaiphun L, Maelankiri L, Parker M, Day NP, White NJ, Nosten F.

Int Health. 2010 Jun;2(2):123-9. doi: 10.1016/j.inhe.2010.02.001.


Exploring the contribution of candidate genes to artemisinin resistance in Plasmodium falciparum.

Imwong M, Dondorp AM, Nosten F, Yi P, Mungthin M, Hanchana S, Das D, Phyo AP, Lwin KM, Pukrittayakamee S, Lee SJ, Saisung S, Koecharoen K, Nguon C, Day NP, Socheat D, White NJ.

Antimicrob Agents Chemother. 2010 Jul;54(7):2886-92. doi: 10.1128/AAC.00032-10. Epub 2010 Apr 26.


Artemisinin resistance in Plasmodium falciparum malaria.

Dondorp AM, Nosten F, Yi P, Das D, Phyo AP, Tarning J, Lwin KM, Ariey F, Hanpithakpong W, Lee SJ, Ringwald P, Silamut K, Imwong M, Chotivanich K, Lim P, Herdman T, An SS, Yeung S, Singhasivanon P, Day NP, Lindegardh N, Socheat D, White NJ.

N Engl J Med. 2009 Jul 30;361(5):455-67. doi: 10.1056/NEJMoa0808859. Erratum in: N Engl J Med. 2009 Oct 22;361(17):1714.


Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment.

Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, Brockman A, Anderson T, McGready R, Phaiphun L, Proux S, van Vugt M, Hutagalung R, Lwin KM, Phyo AP, Preechapornkul P, Imwong M, Pukrittayakamee S, Singhasivanon P, White NJ, Nosten F.

PLoS One. 2009;4(2):e4551. doi: 10.1371/journal.pone.0004551. Epub 2009 Feb 23.


Clinically uncomplicated Plasmodium falciparum malaria with high schizontaemia: a case report.

Lwin KM, Ashley EA, Proux S, Silamut K, Nosten F, McGready R.

Malar J. 2008 Apr 11;7:57. doi: 10.1186/1475-2875-7-57.


An open label randomized comparison of mefloquine-artesunate as separate tablets vs. a new co-formulated combination for the treatment of uncomplicated multidrug-resistant falciparum malaria in Thailand.

Ashley EA, Lwin KM, McGready R, Simon WH, Phaiphun L, Proux S, Wangseang N, Taylor W, Stepniewska K, Nawamaneerat W, Thwai KL, Barends M, Leowattana W, Olliaro P, Singhasivanon P, White NJ, Nosten F.

Trop Med Int Health. 2006 Nov;11(11):1653-60.


Fertility in Rangoon, 1964.

Aye B, Lwin KM.

Union Burma J Life Sci. 1970;3(1):81-6.


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