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Items: 45

1.

Identification and relative quantification of neuropeptides from the endocrine tissues.

Boonen K, Husson SJ, Landuyt B, Baggerman G, Hayakawa E, Luyten WH, Schoofs L.

Methods Mol Biol. 2010;615:191-206. doi: 10.1007/978-1-60761-535-4_15.

PMID:
20013210
2.

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

Peeters PJ, Baker A, Goris I, Daneels G, Verhasselt P, Luyten WH, Geysen JJ, Kass SU, Moechars DW.

Brain Res Dev Brain Res. 2004 Jun 21;150(2):89-101.

PMID:
15158073
3.

Functional study of rat 5-HT2A receptors using antisense oligonucleotides.

Van Oekelen D, Megens A, Meert T, Luyten WH, Leysen JE.

J Neurochem. 2003 Jun;85(5):1087-100.

4.

Ten years of antisense inhibition of brain G-protein-coupled receptor function.

Van Oekelen D, Luyten WH, Leysen JE.

Brain Res Brain Res Rev. 2003 May;42(2):123-42. Review.

PMID:
12738054
5.

Gene-Expression - Based Responses to Drug Treatment.

De Backer MD, Thurmond RL, Carmen AA, Luyten WH.

Drug News Perspect. 2002 Apr;15(3):155-165.

PMID:
12677258
6.

5-HT2A and 5-HT2C receptors and their atypical regulation properties.

Van Oekelen D, Luyten WH, Leysen JE.

Life Sci. 2003 Apr 18;72(22):2429-49. Review.

PMID:
12650852
7.

Role of 5-HT(2) receptors in the tryptamine-induced 5-HT syndrome in rats.

Van Oekelen D, Megens A, Meert T, Luyten WH, Leysen JE.

Behav Pharmacol. 2002 Jul;13(4):313-8.

PMID:
12218512
8.

Functional genomics approaches for the identification and validation of antifungal drug targets.

De Backer MD, Van Dijck P, Luyten WH.

Am J Pharmacogenomics. 2002;2(2):113-27. Review.

PMID:
12083946
9.
10.

Different regulation of rat 5-HT(2A) and rat 5-HT(2C) receptors in NIH 3T3 cells upon exposure to 5-HT and pipamperone.

Oekelen DV, Jurzak M, Van de Wiel D, Van Hecke G, Luyten WH, Leysen JE.

Eur J Pharmacol. 2001 Aug 3;425(1):21-32.

PMID:
11672571
11.

Genomic profiling of the response of Candida albicans to itraconazole treatment using a DNA microarray.

De Backer MD, Ilyina T, Ma XJ, Vandoninck S, Luyten WH, Vanden Bossche H.

Antimicrob Agents Chemother. 2001 Jun;45(6):1660-70.

12.

Galantamine is an allosterically potentiating ligand of the human alpha4/beta2 nAChR.

Samochocki M, Zerlin M, Jostock R, Groot Kormelink PJ, Luyten WH, Albuquerque EX, Maelicke A.

Acta Neurol Scand Suppl. 2000;176:68-73.

PMID:
11261808
13.

An antisense-based functional genomics approach for identification of genes critical for growth of Candida albicans.

De Backer MD, Nelissen B, Logghe M, Viaene J, Loonen I, Vandoninck S, de Hoogt R, Dewaele S, Simons FA, Verhasselt P, Vanhoof G, Contreras R, Luyten WH.

Nat Biotechnol. 2001 Mar;19(3):235-41. Erratum in: Nat Biotechnol 2001 Jul;19(7):681.

PMID:
11231556
14.

G-protein sensitivity of ligand binding to human dopamine D(2) and D(3) receptors expressed in Escherichia coli: clues for a constrained D(3) receptor structure.

Vanhauwe JF, Josson K, Luyten WH, Driessen AJ, Leysen JE.

J Pharmacol Exp Ther. 2000 Oct;295(1):274-83.

PMID:
10991990
15.

Cloning and characterization of human histone deacetylase 8.

Van den Wyngaert I, de Vries W, Kremer A, Neefs J, Verhasselt P, Luyten WH, Kass SU.

FEBS Lett. 2000 Jul 28;478(1-2):77-83.

16.

Quantitative autoradiographic distribution of gamma-hydroxybutyric acid binding sites in human and monkey brain.

Castelli MP, Mocci I, Langlois X, Gommerendagger W, Luyten WH, Leysen JE, Gessa GL.

Brain Res Mol Brain Res. 2000 May 31;78(1-2):91-9.

PMID:
10891588
17.
18.

Human 5-hydroxytryptamine(5A) receptors activate coexpressed G(i) and G(o) proteins in Spodoptera frugiperda 9 cells.

Francken BJ, Josson K, Lijnen P, Jurzak M, Luyten WH, Leysen JE.

Mol Pharmacol. 2000 May;57(5):1034-44.

PMID:
10779389
19.

Single allele knock-out of Candida albicans CGT1 leads to unexpected resistance to hygromycin B and elevated temperature.

De Backer MD, de Hoogt RA, Froyen G, Odds FC, Simons F, Contreras R, Luyten WH.

Microbiology. 2000 Feb;146 ( Pt 2):353-65.

PMID:
10708374
20.

Presence of substance P and neurokinin 1 receptors in human sputum macrophages and U-937 cells.

Germonpre PR, Bullock GR, Lambrecht BN, Van De Velde V, Luyten WH, Joos GF, Pauwels RA.

Eur Respir J. 1999 Oct;14(4):776-82.

21.

Transformation of Candida albicans by electroporation.

De Backer MD, Maes D, Vandoninck S, Logghe M, Contreras R, Luyten WH.

Yeast. 1999 Nov;15(15):1609-18.

22.

Comparison of the ligand binding and signaling properties of human dopamine D(2) and D(3) receptors in Chinese hamster ovary cells.

Vanhauwe JF, Fraeyman N, Francken BJ, Luyten WH, Leysen JE.

J Pharmacol Exp Ther. 1999 Aug;290(2):908-16.

PMID:
10411608
23.

Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.

Bonaventure P, Umans L, Bakker MH, Cras P, Langlois X, Luyten WH, Megens AA, Serneels L, Van Leuven F, Leysen JE.

Mol Pharmacol. 1999 Jul;56(1):54-67.

PMID:
10385684
24.

Efficient expression of neurotransmitter receptors in mammalian cells: use of inducible expression systems.

Vanhoenacker P, Van den Bogerd I, Gommeren W, Luyten WH, Leysen JE, Haegeman G.

Ann N Y Acad Sci. 1998 Dec 15;861:236-7. No abstract available.

PMID:
9928263
25.

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase.

Blasina A, de Weyer IV, Laus MC, Luyten WH, Parker AE, McGowan CH.

Curr Biol. 1999 Jan 14;9(1):1-10.

26.

The human 5-ht5A receptor couples to Gi/Go proteins and inhibits adenylate cyclase in HEK 293 cells.

Francken BJ, Jurzak M, Vanhauwe JF, Luyten WH, Leysen JE.

Eur J Pharmacol. 1998 Nov 20;361(2-3):299-309.

PMID:
9865521
27.

Structure of the human histamine H1 receptor gene.

De Backer MD, Loonen I, Verhasselt P, Neefs JM, Luyten WH.

Biochem J. 1998 Nov 1;335 ( Pt 3):663-70.

28.

Identification of a human homologue of the Schizosaccharomyces pombe rad17+ checkpoint gene.

Parker AE, Van de Weyer I, Laus MC, Verhasselt P, Luyten WH.

J Biol Chem. 1998 Jul 17;273(29):18340-6. Erratum in: J Biol Chem 1999 Aug 20;274(34):24438.

29.

A human homologue of the Schizosaccharomyces pombe rad1+ checkpoint gene encodes an exonuclease.

Parker AE, Van de Weyer I, Laus MC, Oostveen I, Yon J, Verhasselt P, Luyten WH.

J Biol Chem. 1998 Jul 17;273(29):18332-9.

30.

A reporter mutation approach shows incorporation of the "orphan" subunit beta3 into a functional nicotinic receptor.

Groot-Kormelink PJ, Luyten WH, Colquhoun D, Sivilotti LG.

J Biol Chem. 1998 Jun 19;273(25):15317-20.

31.

Agonistic properties of alniditan, sumatriptan and dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian cell lines.

Lesage AS, Wouters R, Van Gompel P, Heylen L, Vanhoenacker P, Haegeman G, Luyten WH, Leysen JE.

Br J Pharmacol. 1998 Apr;123(8):1655-65.

32.

Cloning and analysis of a novel human putative DNA methyltransferase.

Van den Wyngaert I, Sprengel J, Kass SU, Luyten WH.

FEBS Lett. 1998 Apr 17;426(2):283-9.

33.

5HT1B and 5HT1D receptor mRNA differential co-localization with peptide mRNA in the guinea pig trigeminal ganglion.

Bonaventure P, Voorn P, Luyten WH, Leysen JE.

Neuroreport. 1998 Mar 9;9(4):641-5.

PMID:
9559931
34.
36.

Stable, high-level expression of human serotonin receptors in L929 cells using an inducible expression system.

Vanhoenacker P, Gommeren W, Luyten WH, Leysen JE, Haegeman G.

Receptors Channels. 1997;5(3-4):125-37.

PMID:
9606717
37.
38.

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding.

Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, De Loore K, Leysen JE.

Psychopharmacology (Berl). 1996 Mar;124(1-2):57-73.

PMID:
8935801
39.

Genomic cloning, heterologous expression and pharmacological characterization of a human histamine H1 receptor.

De Backer MD, Gommeren W, Moereels H, Nobels G, Van Gompel P, Leysen JE, Luyten WH.

Biochem Biophys Res Commun. 1993 Dec 30;197(3):1601-8.

PMID:
8280179
40.

Receptor cloning and heterologous expression--towards a new tool for drug discovery.

Luyten WH, Leysen JE.

Trends Biotechnol. 1993 Jun;11(6):247-54. Review.

PMID:
7764062
42.
43.

Autoradiographic evidence for the occlusion of rat brain dopamine D3 receptors in vivo.

Schotte A, Janssen PF, Gommeren W, Luyten WH, Leysen JE.

Eur J Pharmacol. 1992 Aug 6;218(2-3):373-5.

PMID:
1425949
44.
45.

A model for the acetylcholine binding site of the nicotinic acetylcholine receptor.

Luyten WH.

J Neurosci Res. 1986;16(1):51-73. Review.

PMID:
3528512

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