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Items: 42

1.

A Compact and Synthetically Accessible Fluorine-18 Labelled Cyclooctyne Prosthetic Group for Labelling of Biomolecules by Copper-free Click Chemistry.

Murrell E, Kovacs MS, Luyt LG.

ChemMedChem. 2018 Jun 19. doi: 10.1002/cmdc.201800334. [Epub ahead of print]

PMID:
29923326
2.

Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice.

Sullivan R, McGirr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L, Dhanvantari S.

J Endocr Soc. 2017 Dec 28;2(2):178-189. doi: 10.1210/js.2017-00433. eCollection 2018 Feb 1.

3.

Design of peptide mimetics to block pro-inflammatory functions of HA fragments.

Hauser-Kawaguchi A, Luyt LG, Turley E.

Matrix Biol. 2018 Jan 31. pii: S0945-053X(17)30444-4. doi: 10.1016/j.matbio.2018.01.021. [Epub ahead of print] Review.

PMID:
29408009
4.

Development of Candidates for Positron Emission Tomography (PET) Imaging of Ghrelin Receptor in Disease: Design, Synthesis, and Evaluation of Fluorine-Bearing Quinazolinone Derivatives.

Hou J, Kovacs MS, Dhanvantari S, Luyt LG.

J Med Chem. 2018 Feb 8;61(3):1261-1275. doi: 10.1021/acs.jmedchem.7b01754. Epub 2018 Jan 30.

PMID:
29327929
5.

Viral nanoparticles decorated with novel EGFL7 ligands enable intravital imaging of tumor neovasculature.

Cho CF, Yu L, Nsiama TK, Kadam AN, Raturi A, Shukla S, Amadei GA, Steinmetz NF, Luyt LG, Lewis JD.

Nanoscale. 2017 Aug 24;9(33):12096-12109. doi: 10.1039/c7nr02558k.

6.

Structure-Activity Study of Ghrelin(1-8) Resulting in High Affinity Fluorine-Bearing Ligands for the Ghrelin Receptor.

Charron CL, Hou J, McFarland MS, Dhanvantari S, Kovacs MS, Luyt LG.

J Med Chem. 2017 Sep 14;60(17):7256-7266. doi: 10.1021/acs.jmedchem.7b00164. Epub 2017 Aug 24.

PMID:
28719746
7.

Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis.

Bahrami SB, Tolg C, Peart T, Symonette C, Veiseh M, Umoh JU, Holdsworth DW, McCarthy JB, Luyt LG, Bissell MJ, Yazdani A, Turley EA.

Integr Biol (Camb). 2017 Mar 1;9(3):223-237. doi: 10.1039/c7ib00002b. Epub 2017 Feb 20.

8.

Bridging computational modeling with amino acid replacements to investigate GHS-R1a-peptidomimetic recognition.

Hou J, Charron CL, Fowkes MM, Luyt LG.

Eur J Med Chem. 2016 Nov 10;123:822-833. doi: 10.1016/j.ejmech.2016.07.078. Epub 2016 Aug 4.

PMID:
27541265
9.

Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries.

Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE.

ACS Comb Sci. 2016 Jun 13;18(6):271-8. doi: 10.1021/acscombsci.5b00180. Epub 2016 May 23.

10.

Molecular imaging probes derived from natural peptides.

Charron CL, Hickey JL, Nsiama TK, Cruickshank DR, Turnbull WL, Luyt LG.

Nat Prod Rep. 2016 Jun 2;33(6):761-800. doi: 10.1039/c5np00083a. Review.

PMID:
26911790
11.

Novel Methods of Determining Urinary Calculi Composition: Petrographic Thin Sectioning of Calculi and Nanoscale Flow Cytometry Urinalysis.

Gavin CT, Ali SN, Tailly T, Olvera-Posada D, Alenezi H, Power NE, Hou J, St Amant AH, Luyt LG, Wood S, Wu C, Razvi H, Leong HS.

Sci Rep. 2016 Jan 14;6:19328. doi: 10.1038/srep19328.

12.

Molecular Engineering of Thiazole Orange Dye: Change of Fluorescent Signaling from Universal to Specific upon Binding with Nucleic Acids in Bioassay.

Lu YJ, Deng Q, Hou JQ, Hu DP, Wang ZY, Zhang K, Luyt LG, Wong WL, Chow CF.

ACS Chem Biol. 2016 Apr 15;11(4):1019-29. doi: 10.1021/acschembio.5b00987. Epub 2016 Jan 26.

PMID:
26752011
13.

Identification, design and synthesis of tubulin-derived peptides as novel hyaluronan mimetic ligands for the receptor for hyaluronan-mediated motility (RHAMM/HMMR).

Esguerra KV, Tolg C, Akentieva N, Price M, Cho CF, Lewis JD, McCarthy JB, Turley EA, Luyt LG.

Integr Biol (Camb). 2015 Dec;7(12):1547-60. doi: 10.1039/c5ib00222b. Epub 2015 Oct 12.

14.

Evaluation of Anisole-Substituted Boron Difluoride Formazanate Complexes for Fluorescence Cell Imaging.

Maar RR, Barbon SM, Sharma N, Groom H, Luyt LG, Gilroy JB.

Chemistry. 2015 Oct 26;21(44):15589-99. doi: 10.1002/chem.201502821. Epub 2015 Sep 23.

PMID:
26397738
15.

Synthesis and evaluation of optical and PET GLP-1 peptide analogues for GLP-1R imaging.

Behnam Azad B, Rota V, Yu L, McGirr R, St Amant AH, Lee TY, Dhanvantari S, Luyt LG.

Mol Imaging. 2015;14. doi: 0.2310/7290.2014.00057.

PMID:
25762192
16.

Synthesis and cell-based screening of one-bead-one-compound peptide libraries.

Bononi FC, Luyt LG.

Methods Mol Biol. 2015;1248:223-37. doi: 10.1007/978-1-4939-2020-4_15. Review.

PMID:
25616336
17.

Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach.

Hou JQ, Chen SB, Zan LP, Ou TM, Tan JH, Luyt LG, Huang ZS.

Chem Commun (Camb). 2015 Jan 4;51(1):198-201. doi: 10.1039/c4cc06951j.

PMID:
25388435
18.

An integrated imaging probe design: the synthesis of (99m)Tc/Re-containing macrocyclic peptide scaffolds.

Hickey JL, Simpson EJ, Hou J, Luyt LG.

Chemistry. 2015 Jan 7;21(2):568-78. doi: 10.1002/chem.201404774. Epub 2014 Nov 11.

PMID:
25388204
19.

Dual-modal magnetic resonance and fluorescence imaging of atherosclerotic plaques in vivo using VCAM-1 targeted tobacco mosaic virus.

Bruckman MA, Jiang K, Simpson EJ, Randolph LN, Luyt LG, Yu X, Steinmetz NF.

Nano Lett. 2014 Mar 12;14(3):1551-8. doi: 10.1021/nl404816m. Epub 2014 Feb 17.

20.

Characterization of a far-red analog of ghrelin for imaging GHS-R in P19-derived cardiomyocytes.

Douglas GA, McGirr R, Charlton CL, Kagan DB, Hoffman LM, Luyt LG, Dhanvantari S.

Peptides. 2014 Apr;54:81-8. doi: 10.1016/j.peptides.2014.01.011. Epub 2014 Jan 25.

PMID:
24468548
21.

Molecular targeted viral nanoparticles as tools for imaging cancer.

Cho CF, Shukla S, Simpson EJ, Steinmetz NF, Luyt LG, Lewis JD.

Methods Mol Biol. 2014;1108:211-30. doi: 10.1007/978-1-62703-751-8_16.

22.

High-throughput screening of one-bead-one-compound peptide libraries using intact cells.

Cho CF, Behnam Azad B, Luyt LG, Lewis JD.

ACS Comb Sci. 2013 Aug 12;15(8):393-400. doi: 10.1021/co4000584. Epub 2013 Jul 19.

PMID:
23819541
23.

Discovery of novel integrin ligands from combinatorial libraries using a multiplex "beads on a bead" approach.

Cho CF, Amadei GA, Breadner D, Luyt LG, Lewis JD.

Nano Lett. 2012 Nov 14;12(11):5957-65. doi: 10.1021/nl3034043. Epub 2012 Oct 29.

PMID:
23094984
24.

Synthesis of rhenium-centric reverse turn mimics.

Hickey JL, Luyt LG.

Chemistry. 2012 Oct 8;18(41):12999-3007. doi: 10.1002/chem.201201766. Epub 2012 Sep 3.

PMID:
22945687
25.

A RHAMM mimetic peptide blocks hyaluronan signaling and reduces inflammation and fibrogenesis in excisional skin wounds.

Tolg C, Hamilton SR, Zalinska E, McCulloch L, Amin R, Akentieva N, Winnik F, Savani R, Bagli DJ, Luyt LG, Cowman MK, McCarthy JB, Turley EA.

Am J Pathol. 2012 Oct;181(4):1250-70. doi: 10.1016/j.ajpath.2012.06.036. Epub 2012 Aug 11.

26.

Investigation of isomer formation upon coordination of bifunctional histidine analogues with 99mTc/Re(CO)3.

Simpson EJ, Hickey JL, Breadner D, Luyt LG.

Dalton Trans. 2012 Mar 14;41(10):2950-8. doi: 10.1039/c2dt11962e. Epub 2012 Jan 23.

PMID:
22266949
27.

Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative.

Azad BB, Cho CF, Lewis JD, Luyt LG.

Appl Radiat Isot. 2012 Mar;70(3):505-11. doi: 10.1016/j.apradiso.2011.11.054. Epub 2011 Dec 6.

PMID:
22178308
28.

Imaging of homeostatic, neoplastic, and injured tissues by HA-based probes.

Veiseh M, Breadner D, Ma J, Akentieva N, Savani RC, Harrison R, Mikilus D, Collis L, Gustafson S, Lee TY, Koropatnick J, Luyt LG, Bissell MJ, Turley EA.

Biomacromolecules. 2012 Jan 9;13(1):12-22. doi: 10.1021/bm201143c. Epub 2011 Dec 12.

29.

Ghrelin receptor as a novel imaging target for prostatic neoplasms.

Lu C, McFarland MS, Nesbitt RL, Williams AK, Chan S, Gomez-Lemus J, Autran-Gomez AM, Al-Zahrani A, Chin JL, Izawa JI, Luyt LG, Lewis JD.

Prostate. 2012 Jun 1;72(8):825-33. doi: 10.1002/pros.21484. Epub 2011 Sep 14. Erratum in: Prostate. 2016 Feb;76(3):335.

PMID:
21919027
30.

Design and characterization of a fluorescent ghrelin analog for imaging the growth hormone secretagogue receptor 1a.

McGirr R, McFarland MS, McTavish J, Luyt LG, Dhanvantari S.

Regul Pept. 2011 Dec 10;172(1-3):69-76. doi: 10.1016/j.regpep.2011.08.011. Epub 2011 Sep 3.

PMID:
21893106
31.

Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors.

Steinmetz NF, Ablack AL, Hickey JL, Ablack J, Manocha B, Mymryk JS, Luyt LG, Lewis JD.

Small. 2011 Jun 20;7(12):1664-72. doi: 10.1002/smll.201000435. Epub 2011 Apr 26.

32.

RHAMM promotes interphase microtubule instability and mitotic spindle integrity through MEK1/ERK1/2 activity.

Tolg C, Hamilton SR, Morningstar L, Zhang J, Zhang S, Esguerra KV, Telmer PG, Luyt LG, Harrison R, McCarthy JB, Turley EA.

J Biol Chem. 2010 Aug 20;285(34):26461-74. doi: 10.1074/jbc.M110.121491. Epub 2010 Jun 17.

33.

Design, synthesis and in vitro characterization of Glucagon-Like Peptide-1 derivatives for pancreatic beta cell imaging by SPECT.

Behnam Azad B, Rota VA, Breadner D, Dhanvantari S, Luyt LG.

Bioorg Med Chem. 2010 Feb;18(3):1265-72. doi: 10.1016/j.bmc.2009.12.032. Epub 2009 Dec 16.

PMID:
20056547
34.

A fast, reproducible and low-cost method for sequence deconvolution of 'on-bead' peptides via 'on-target' maldi-TOF/TOF mass spectrometry.

Amadei GA, Cho CF, Lewis JD, Luyt LG.

J Mass Spectrom. 2010 Mar;45(3):241-51. doi: 10.1002/jms.1708.

PMID:
20041400
35.

Synthesis of bombesin-functionalized iron oxide nanoparticles and their specific uptake in prostate cancer cells.

Martin AL, Hickey JL, Ablack AL, Lewis JD, Luyt LG, Gillies ER.

J Nanopart Res. 2009 Jun 23;12(5):1599-1608.

36.

Fluorine and rhenium substituted ghrelin analogues as potential imaging probes for the growth hormone secretagogue receptor.

Rosita D, Dewit MA, Luyt LG.

J Med Chem. 2009 Apr 23;52(8):2196-203. doi: 10.1021/jm8014519.

PMID:
19323558
37.

Design and synthesis of functionalized cyclopentadienyl tricarbonylmetal complexes for technetium-94m PET imaging of estrogen receptors.

Bigott HM, Parent E, Luyt LG, Katzenellenbogen JA, Welch MJ.

Bioconjug Chem. 2005 Mar-Apr;16(2):255-64.

PMID:
15769078
39.

A trithiolate tripodal bifunctional ligand for the radiolabeling of peptides with gallium(III).

Luyt LG, Katzenellenbogen JA.

Bioconjug Chem. 2002 Sep-Oct;13(5):1140-5.

PMID:
12236797
40.

Single isomer technetium-99m tamoxifen conjugates.

Hunter DH, Luyt LG.

Bioconjug Chem. 2000 Mar-Apr;11(2):175-81.

PMID:
10725094
41.
42.

Survey of total aflatoxin content in peanuts, peanut butter, and other foodstuffs.

Gelda CS, Luyt LJ.

Ann Nutr Aliment. 1977;31(4-6):477-83. No abstract available.

PMID:
613912

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