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Development of Quality Measures in Cirrhosis by the Practice Metrics Committee of the American Association for the Study of Liver Diseases.

Kanwal F, Tapper EB, Ho C, Asrani SK, Ovchinsky N, Poterucha J, Flores A, Ankoma-Sey V, Luxon B, Volk M.

Hepatology. 2019 Apr;69(4):1787-1797. doi: 10.1002/hep.30489. Epub 2019 Mar 12. Erratum in: Hepatology. 2019 Nov;70(5):1880.


Patient-reported outcomes in cirrhosis: A scoping review of the literature.

Tapper EB, Kanwal F, Asrani SK, Ho C, Ovchinsky N, Poterucha J, Flores A, Smith JE, Ankoma-Sey V, Luxon B, Volk ML.

Hepatology. 2018 Jun;67(6):2375-2383. doi: 10.1002/hep.29756. Epub 2018 Apr 19. Review.


Transcriptional Profiling in Experimental Visceral Leishmaniasis Reveals a Broad Splenic Inflammatory Environment that Conditions Macrophages toward a Disease-Promoting Phenotype.

Kong F, Saldarriaga OA, Spratt H, Osorio EY, Travi BL, Luxon BA, Melby PC.

PLoS Pathog. 2017 Jan 31;13(1):e1006165. doi: 10.1371/journal.ppat.1006165. eCollection 2017 Jan.


Transcriptomics of Environmental Enrichment Reveals a Role for Retinoic Acid Signaling in Addiction.

Zhang Y, Kong F, Crofton EJ, Dragosljvich SN, Sinha M, Li D, Fan X, Koshy S, Hommel JD, Spratt HM, Luxon BA, Green TA.

Front Mol Neurosci. 2016 Nov 16;9:119. eCollection 2016.


Convergent transcriptomics and proteomics of environmental enrichment and cocaine identifies novel therapeutic strategies for addiction.

Zhang Y, Crofton EJ, Fan X, Li D, Kong F, Sinha M, Luxon BA, Spratt HM, Lichti CF, Green TA.

Neuroscience. 2016 Dec 17;339:254-266. doi: 10.1016/j.neuroscience.2016.09.051. Epub 2016 Oct 4.


Vascular endothelial growth factor promotes the activation of hepatic stellate cells in chronic schistosomiasis.

Luo J, Liang Y, Kong F, Qiu J, Liu X, Chen A, Luxon BA, Wu HW, Wang Y.

Immunol Cell Biol. 2017 Apr;95(4):399-407. doi: 10.1038/icb.2016.109. Epub 2016 Nov 3.


Differential inflammasome activation signatures following intracellular infection of human macrophages with Mycobacterium bovis BCG or Trypanosoma cruzi.

Huante MB, Gupta S, Calderon VC, Koo SJ, Sinha M, Luxon BA, Garg NJ, Endsley JJ.

Tuberculosis (Edinb). 2016 Dec;101S:S35-S44. doi: 10.1016/ Epub 2016 Sep 28.


Medical co-morbidities of patients with haemophilia: pain, obesity and hepatitis C.

Witkop ML, Peerlinck K, Luxon BA.

Haemophilia. 2016 Jul;22 Suppl 5:47-53. doi: 10.1111/hae.12996. Review.


Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.

Bhakat KK, Sengupta S, Adeniyi VF, Roychoudhury S, Nath S, Bellot LJ, Feng D, Mantha AK, Sinha M, Qiu S, Luxon BA.

Oncotarget. 2016 Apr 19;7(16):22590-604. doi: 10.18632/oncotarget.8026.


Direct and Indirect Serum Markers of Liver Fibrosis Compared with Transient Elastography among Women in the Women's Interagency HIV Study.

Kassaye S, Li Y, Huhn G, Peters MG, French AL, Tien PC, Luxon B, Plankey MW.

J AIDS Clin Res. 2015 Apr;6(4). pii: 446.


Analysis of the TGFβ-induced program in primary airway epithelial cells shows essential role of NF-κB/RelA signaling network in type II epithelial mesenchymal transition.

Tian B, Li X, Kalita M, Widen SG, Yang J, Bhavnani SK, Dang B, Kudlicki A, Sinha M, Kong F, Wood TG, Luxon BA, Brasier AR.

BMC Genomics. 2015 Jul 18;16:529. doi: 10.1186/s12864-015-1707-x.


Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.

Dey N, Sinha M, Gupta S, Gonzalez MN, Fang R, Endsley JJ, Luxon BA, Garg NJ.

PLoS One. 2014 Nov 5;9(11):e111539. doi: 10.1371/journal.pone.0111539. eCollection 2014.


Potential catalysts in therapeutics.

Luxon BA.

Liver Transpl. 2014 Nov;20 Suppl 2:S22-31. doi: 10.1002/lt.23971. Review.


Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens.

Lichti CF, Fan X, English RD, Zhang Y, Li D, Kong F, Sinha M, Andersen CR, Spratt H, Luxon BA, Green TA.

Front Behav Neurosci. 2014 Jul 21;8:246. doi: 10.3389/fnbeh.2014.00246. eCollection 2014.


Cognitive enhancing treatment with a PPARγ agonist normalizes dentate granule cell presynaptic function in Tg2576 APP mice.

Nenov MN, Laezza F, Haidacher SJ, Zhao Y, Sadygov RG, Starkey JM, Spratt H, Luxon BA, Dineley KT, Denner L.

J Neurosci. 2014 Jan 15;34(3):1028-36. doi: 10.1523/JNEUROSCI.3413-13.2014.


Metabolomics in asthma.

Luxon BA.

Adv Exp Med Biol. 2014;795:207-20. doi: 10.1007/978-1-4614-8603-9_13. Review.


So you want to be a hepatologist?

Luxon BA.

Gastroenterology. 2013 Dec;145(6):1182-5. doi: 10.1053/j.gastro.2013.10.023. Epub 2013 Oct 19. No abstract available.


Vaccines based on structure-based design provide protection against infectious diseases.

Thomas S, Luxon BA.

Expert Rev Vaccines. 2013 Nov;12(11):1301-11. doi: 10.1586/14760584.2013.840092. Epub 2013 Oct 4. Review.


Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways.

Denner LA, Rodriguez-Rivera J, Haidacher SJ, Jahrling JB, Carmical JR, Hernandez CM, Zhao Y, Sadygov RG, Starkey JM, Spratt H, Luxon BA, Wood TG, Dineley KT.

J Neurosci. 2012 Nov 21;32(47):16725-35a. doi: 10.1523/JNEUROSCI.2153-12.2012.


Innate immune tolerance and the role of kupffer cells in differential responses to interferon therapy among patients with HCV genotype 1 infection.

Lau DT, Negash A, Chen J, Crochet N, Sinha M, Zhang Y, Guedj J, Holder S, Saito T, Lemon SM, Luxon BA, Perelson AS, Gale M Jr.

Gastroenterology. 2013 Feb;144(2):402-413.e12. doi: 10.1053/j.gastro.2012.10.044. Epub 2012 Nov 2.


The National NeuroAIDS Tissue Consortium brain gene array: two types of HIV-associated neurocognitive impairment.

Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, Luxon BA, Morgello S; National NeuroAIDS Tissue Consortium.

PLoS One. 2012;7(9):e46178. doi: 10.1371/journal.pone.0046178. Epub 2012 Sep 26.


Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics.

Wu P, Zhao Y, Haidacher SJ, Wang E, Parsley MO, Gao J, Sadygov RG, Starkey JM, Luxon BA, Spratt H, Dewitt DS, Prough DS, Denner L.

J Neurotrauma. 2013 May 1;30(9):775-88. doi: 10.1089/neu.2012.2391. Epub 2012 Sep 20.


Proteomics improves the prediction of burns mortality: results from regression spline modeling.

Finnerty CC, Ju H, Spratt H, Victor S, Jeschke MG, Hegde S, Bhavnani SK, Luxon BA, Brasier AR, Herndon DN.

Clin Transl Sci. 2012 Jun;5(3):243-9. doi: 10.1111/j.1752-8062.2012.00412.x. Epub 2012 May 15.


1H Nuclear Magnetic Resonance (NMR) Metabolomic Study of Chronic Organophosphate Exposure in Rats.

Alam TM, Neerathilingam M, Alam MK, Volk DE, Ansari GA, Sarkar S, Luxon BA.

Metabolites. 2012 Jul 24;2(3):479-95. doi: 10.3390/metabo2030479.


Structure-based vaccines provide protection in a mouse model of ehrlichiosis.

Thomas S, Thirumalapura NR, Crocquet-Valdes PA, Luxon BA, Walker DH.

PLoS One. 2011;6(11):e27981. doi: 10.1371/journal.pone.0027981. Epub 2011 Nov 17.


Effects of progesterone treatment on expression of genes involved in uterine quiescence.

Soloff MS, Jeng YJ, Izban MG, Sinha M, Luxon BA, Stamnes SJ, England SK.

Reprod Sci. 2011 Aug;18(8):781-97. doi: 10.1177/1933719111398150.


Biliverdin inhibits hepatitis C virus nonstructural 3/4A protease activity: mechanism for the antiviral effects of heme oxygenase?

Zhu Z, Wilson AT, Luxon BA, Brown KE, Mathahs MM, Bandyopadhyay S, McCaffrey AP, Schmidt WN.

Hepatology. 2010 Dec;52(6):1897-905. doi: 10.1002/hep.23921.


Bone disorders in chronic liver diseases.

Luxon BA.

Curr Gastroenterol Rep. 2011 Feb;13(1):40-8. doi: 10.1007/s11894-010-0166-4. Review.


Requirement of TGFbeta signaling for SMO-mediated carcinogenesis.

Fan Q, He M, Sheng T, Zhang X, Sinha M, Luxon B, Zhao X, Xie J.

J Biol Chem. 2010 Nov 19;285(47):36570-6. doi: 10.1074/jbc.C110.164442. Epub 2010 Sep 21.


Proteomic analysis of Pichindé virus infection identifies differential expression of prothymosin-alpha.

Bowick GC, Soman KV, Wang H, Aronson JF, Luxon BA, Lomas LO, Gorenstein DG, Herzog NK.

J Biomed Biotechnol. 2010;2010. pii: 956823. doi: 10.1155/2010/956823. Epub 2010 Apr 18.


1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats.

Neerathilingam M, Volk DE, Sarkar S, Alam TM, Alam MK, Ansari GA, Luxon BA.

Toxicol Lett. 2010 Nov 10;199(1):10-6. doi: 10.1016/j.toxlet.2010.07.013. Epub 2010 Aug 3.


¹H and ³¹P NMR lipidome of ethanol-induced fatty liver.

Fernando H, Kondraganti S, Bhopale KK, Volk DE, Neerathilingam M, Kaphalia BS, Luxon BA, Boor PJ, Shakeel Ansari GA.

Alcohol Clin Exp Res. 2010 Nov;34(11):1937-47. doi: 10.1111/j.1530-0277.2010.01283.x.


Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry.

Starkey JM, Zhao Y, Sadygov RG, Haidacher SJ, Lejeune WS, Dey N, Luxon BA, Kane MA, Napoli JL, Denner L, Tilton RG.

PLoS One. 2010 Jun 14;5(6):e11095. doi: 10.1371/journal.pone.0011095.


Pathway signature and cellular differentiation in clear cell renal cell carcinoma.

Tun HW, Marlow LA, von Roemeling CA, Cooper SJ, Kreinest P, Wu K, Luxon BA, Sinha M, Anastasiadis PZ, Copland JA.

PLoS One. 2010 May 18;5(5):e10696. doi: 10.1371/journal.pone.0010696.


Training for a career in hepatology: which path to take?

Luxon BA.

Curr Gastroenterol Rep. 2010 Feb;12(1):76-81. doi: 10.1007/s11894-009-0086-3. Review.


The "Iowa get screened" colon cancer screening program.

Levy BT, Daly JM, Luxon B, Merchant ML, Xu Y, Levitz CE, Wilbur JK.

J Prim Care Community Health. 2010 Apr 1;1(1):43-9. doi: 10.1177/2150131909352191.


Hepatitis C virus core protein enhances Telomerase activity in Huh7 cells.

Zhu Z, Wilson AT, Gopalakrishna K, Brown KE, Luxon BA, Schmidt WN.

J Med Virol. 2010 Feb;82(2):239-48. doi: 10.1002/jmv.21644.


Allergen challenge induces Ifng dependent GTPases in the lungs as part of a Th1 transcriptome response in a murine model of allergic asthma.

Dharajiya N, Vaidya S, Sinha M, Luxon B, Boldogh I, Sur S.

PLoS One. 2009 Dec 21;4(12):e8172. doi: 10.1371/journal.pone.0008172.


Attenuated and lethal variants of Pichindé virus induce differential patterns of NF-kappaB activation suggesting a potential target for novel therapeutics.

Bowick GC, Fennewald SM, Zhang L, Yang X, Aronson JF, Shope RE, Luxon BA, Gorenstein DG, Herzog NK.

Viral Immunol. 2009 Dec;22(6):457-62. doi: 10.1089/vim.2009.0034.


Investigation of chemometric instrumental transfer methods for high-resolution NMR.

Alam TM, Alam MK, McIntyre SK, Volk DE, Neerathilingam M, Luxon BA.

Anal Chem. 2009 Jun 1;81(11):4433-43. doi: 10.1021/ac900262g.


Global transcription profiling and virulence potential of Streptococcus pneumoniae after serial passage.

Pandya U, Sinha M, Luxon BA, Watson DA, Niesel DW.

Gene. 2009 Aug 15;443(1-2):22-31. doi: 10.1016/j.gene.2009.04.014. Epub 2009 May 3.


Integrin alpha6beta4 controls the expression of genes associated with cell motility, invasion, and metastasis, including S100A4/metastasin.

Chen M, Sinha M, Luxon BA, Bresnick AR, O'Connor KL.

J Biol Chem. 2009 Jan 16;284(3):1484-94. doi: 10.1074/jbc.M803997200. Epub 2008 Nov 14.


Analysis of the differential host cell nuclear proteome induced by attenuated and virulent hemorrhagic arenavirus infection.

Bowick GC, Spratt HM, Hogg AE, Endsley JJ, Wiktorowicz JE, Kurosky A, Luxon BA, Gorenstein DG, Herzog NK.

J Virol. 2009 Jan;83(2):687-700. doi: 10.1128/JVI.01281-08. Epub 2008 Nov 12.


Heme oxygenase-1 suppresses hepatitis C virus replication and increases resistance of hepatocytes to oxidant injury.

Zhu Z, Wilson AT, Mathahs MM, Wen F, Brown KE, Luxon BA, Schmidt WN.

Hepatology. 2008 Nov;48(5):1430-9. doi: 10.1002/hep.22491.


Transcriptional profiling of mRNA expression in the mouse distal colon.

Hoogerwerf WA, Sinha M, Conesa A, Luxon BA, Shahinian VB, Cornélissen G, Halberg F, Bostwick J, Timm J, Cassone VM.

Gastroenterology. 2008 Dec;135(6):2019-29. doi: 10.1053/j.gastro.2008.08.048. Epub 2008 Sep 3.


CadA negatively regulates Escherichia coli O157:H7 adherence and intestinal colonization.

Vazquez-Juarez RC, Kuriakose JA, Rasko DA, Ritchie JM, Kendall MM, Slater TM, Sinha M, Luxon BA, Popov VL, Waldor MK, Sperandio V, Torres AG.

Infect Immun. 2008 Nov;76(11):5072-81. doi: 10.1128/IAI.00677-08. Epub 2008 Sep 15.


Diagnosis and treatment of autoimmune hepatitis.

Luxon BA.

Gastroenterol Clin North Am. 2008 Jun;37(2):461-78, vii-viii. doi: 10.1016/j.gtc.2008.02.002.


Combinatorial selection of a single stranded DNA thioaptamer targeting TGF-beta1 protein.

Kang J, Lee MS, Copland JA 3rd, Luxon BA, Gorenstein DG.

Bioorg Med Chem Lett. 2008 Mar 15;18(6):1835-9. doi: 10.1016/j.bmcl.2008.02.023. Epub 2008 Feb 13.


Identification of human metapneumovirus-induced gene networks in airway epithelial cells by microarray analysis.

Bao X, Sinha M, Liu T, Hong C, Luxon BA, Garofalo RP, Casola A.

Virology. 2008 Apr 25;374(1):114-27. doi: 10.1016/j.virol.2007.12.024. Epub 2008 Jan 29.


Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma.

Gumz ML, Zou H, Kreinest PA, Childs AC, Belmonte LS, LeGrand SN, Wu KJ, Luxon BA, Sinha M, Parker AS, Sun LZ, Ahlquist DA, Wood CG, Copland JA.

Clin Cancer Res. 2007 Aug 15;13(16):4740-9.

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