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Items: 25


Anti-ICOSL New Antigen Receptor Domains Inhibit T Cell Proliferation and Reduce the Development of Inflammation in the Collagen-Induced Mouse Model of Rheumatoid Arthritis.

O'Dwyer R, Kovaleva M, Zhang J, Steven J, Cummins E, Luxenberg D, Darmanin-Sheehan A, Carvalho MF, Whitters M, Saunders K, Barelle CJ.

J Immunol Res. 2018 Oct 17;2018:4089459. doi: 10.1155/2018/4089459. eCollection 2018.


CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery.

Fennell BJ, McDonnell B, Tam AS, Chang L, Steven J, Broadbent ID, Gao H, Kieras E, Alley J, Luxenberg D, Edmonds J, Fitz LJ, Miao W, Whitters MJ, Medley QG, Guo YJ, Darmanin-Sheehan A, Autin B, Shúilleabháin DN, Cummins E, King A, Krebs MR, Grace C, Hickling TP, Boisvert A, Zhong X, McKenna M, Francis C, Olland S, Bloom L, Paulsen J, Somers W, Jensen A, Lin L, Finlay WJ, Cunningham O.

MAbs. 2013 Nov-Dec;5(6):882-95. doi: 10.4161/mabs.26201. Epub 2013 Aug 21.


Pyroglutamate and O-linked glycan determine functional production of anti-IL17A and anti-IL22 peptide-antibody bispecific genetic fusions.

Zhong X, Kieras E, Sousa E, D'Antona A, Baber JC, He T, Desharnais J, Wood L, Luxenberg D, Stahl M, Kriz R, Lin L, Somers W, Fitz LJ, Wright JF.

J Biol Chem. 2013 Jan 11;288(2):1409-19. doi: 10.1074/jbc.M112.417717. Epub 2012 Nov 26.


Unexpected mucin-type O-glycosylation and host-specific N-glycosylation of human recombinant interleukin-17A expressed in a human kidney cell line.

Geoghegan KF, Song X, Hoth LR, Feng X, Shanker S, Quazi A, Luxenberg DP, Wright JF, Griffor MC.

Protein Expr Purif. 2013 Jan;87(1):27-34. doi: 10.1016/j.pep.2012.09.013. Epub 2012 Oct 13.


Short-term memory and working memory in children with blindness: support for a domain general or domain specific system?

Swanson HL, Luxenberg D.

Child Neuropsychol. 2009 May;15(3):280-94. doi: 10.1080/09297040802524206. Epub 2008 Dec 2.


A simple high-throughput purification method for hit identification in protein screening.

Cummins E, Luxenberg DP, McAleese F, Widom A, Fennell BJ, Darmanin-Sheehan A, Whitters MJ, Bloom L, Gill D, Cunningham O.

J Immunol Methods. 2008 Nov 30;339(1):38-46. doi: 10.1016/j.jim.2008.07.016. Epub 2008 Aug 27.


The human IL-17F/IL-17A heterodimeric cytokine signals through the IL-17RA/IL-17RC receptor complex.

Wright JF, Bennett F, Li B, Brooks J, Luxenberg DP, Whitters MJ, Tomkinson KN, Fitz LJ, Wolfman NM, Collins M, Dunussi-Joannopoulos K, Chatterjee-Kishore M, Carreno BM.

J Immunol. 2008 Aug 15;181(4):2799-805.


IL-22R, IL-10R2, and IL-22BP binding sites are topologically juxtaposed on adjacent and overlapping surfaces of IL-22.

Wu PW, Li J, Kodangattil SR, Luxenberg DP, Bennett F, Martino M, Collins M, Dunussi-Joannopoulos K, Gill DS, Wolfman NM, Fouser LA.

J Mol Biol. 2008 Oct 24;382(5):1168-83. doi: 10.1016/j.jmb.2008.07.046. Epub 2008 Jul 25.


Atrial septal defect: spectrum of care.

Kharouf R, Luxenberg DM, Khalid O, Abdulla R.

Pediatr Cardiol. 2008 Mar;29(2):271-80. Epub 2007 Oct 23. Review.


Identification of an interleukin 17F/17A heterodimer in activated human CD4+ T cells.

Wright JF, Guo Y, Quazi A, Luxenberg DP, Bennett F, Ross JF, Qiu Y, Whitters MJ, Tomkinson KN, Dunussi-Joannopoulos K, Carreno BM, Collins M, Wolfman NM.

J Biol Chem. 2007 May 4;282(18):13447-55. Epub 2007 Mar 13.


PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis.

Carter LL, Leach MW, Azoitei ML, Cui J, Pelker JW, Jussif J, Benoit S, Ireland G, Luxenberg D, Askew GR, Milarski KL, Groves C, Brown T, Carito BA, Percival K, Carreno BM, Collins M, Marusic S.

J Neuroimmunol. 2007 Jan;182(1-2):124-34. Epub 2006 Dec 19.


Aortic stenosis: the spectrum of practice.

Khalid O, Luxenberg DM, Sable C, Benavidez O, Geva T, Hanna B, Abdulla R.

Pediatr Cardiol. 2006 Nov-Dec;27(6):661-9. Epub 2006 Nov 16.


Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides.

Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M, Fouser LA.

J Exp Med. 2006 Oct 2;203(10):2271-9. Epub 2006 Sep 18.


Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.

Stephens GL, McHugh RS, Whitters MJ, Young DA, Luxenberg D, Carreno BM, Collins M, Shevach EM.

J Immunol. 2004 Oct 15;173(8):5008-20.


Duplication of primate and rodent B7-H3 immunoglobulin V- and C-like domains: divergent history of functional redundancy and exon loss.

Ling V, Wu PW, Spaulding V, Kieleczawa J, Luxenberg D, Carreno BM, Collins M.

Genomics. 2003 Sep;82(3):365-77.


Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses.

Bennett F, Luxenberg D, Ling V, Wang IM, Marquette K, Lowe D, Khan N, Veldman G, Jacobs KA, Valge-Archer VE, Collins M, Carreno BM.

J Immunol. 2003 Jan 15;170(2):711-8.


CTLA-4 (CD152) can inhibit T cell activation by two different mechanisms depending on its level of cell surface expression.

Carreno BM, Bennett F, Chau TA, Ling V, Luxenberg D, Jussif J, Baroja ML, Madrenas J.

J Immunol. 2000 Aug 1;165(3):1352-6.


The inhibitory function of CTLA-4 does not require its tyrosine phosphorylation.

Baroja ML, Luxenberg D, Chau T, Ling V, Strathdee CA, Carreno BM, Madrenas J.

J Immunol. 2000 Jan 1;164(1):49-55.


Structural identification of the hematopoietic progenitor antigen ER-MP12 as the vascular endothelial adhesion molecule PECAM-1 (CD31).

Ling V, Luxenberg D, Wang J, Nickbarg E, Leenen PJ, Neben S, Kobayashi M.

Eur J Immunol. 1997 Feb;27(2):509-14.


Bone morphogenetic protein-2 causes commitment and differentiation in C3H10T1/2 and 3T3 cells.

Wang EA, Israel DI, Kelly S, Luxenberg DP.

Growth Factors. 1993;9(1):57-71.


Mandibular reconstruction with a recombinant bone-inducing factor. Functional, histologic, and biomechanical evaluation.

Toriumi DM, Kotler HS, Luxenberg DP, Holtrop ME, Wang EA.

Arch Otolaryngol Head Neck Surg. 1991 Oct;117(10):1101-12.


Purification and characterization of other distinct bone-inducing factors.

Wang EA, Rosen V, Cordes P, Hewick RM, Kriz MJ, Luxenberg DP, Sibley BS, Wozney JM.

Proc Natl Acad Sci U S A. 1988 Dec;85(24):9484-8.


Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins.

Wong GG, Witek JS, Temple PA, Wilkens KM, Leary AC, Luxenberg DP, Jones SS, Brown EL, Kay RM, Orr EC, et al.

Science. 1985 May 17;228(4701):810-5.


Isolation of cDNAs encoding human and gibbon GM-CSF.

Wong GG, Witek-Giannotti JS, Temple PA, Wilkens KM, Leary AC, Luxenberg DP, Jones SS, Brown EL, Kay RM, Orr EC, et al.

Prog Clin Biol Res. 1985;191:351-66.


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