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Items: 38

1.

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes.

Chen J, Loukola A, Gillespie NA, Peterson R, Jia P, Riley B, Maes H, Dick DM, Kendler KS, Damaj MI, Miles MF, Zhao Z, Li MD, Vink JM, Minica CC, Willemsen G, Boomsma DI, Qaiser B, Madden PAF, Korhonen T, Jousilahti P, Hällfors J, Gelernter J, Kranzler HR, Sherva R, Farrer L, Maher B, Vanyukov M, Taylor M, Ware JJ, Munafò MR, Lutz SM, Hokanson JE, Gu F, Landi MT, Caporaso NE, Hancock DB, Gaddis NC, Baker TB, Bierut LJ, Johnson EO, Chenoweth M, Lerman C, Tyndale R, Kaprio J, Chen X.

Nicotine Tob Res. 2019 Jul 11. pii: ntz099. doi: 10.1093/ntr/ntz099. [Epub ahead of print]

PMID:
31294817
2.

Genetic Advances in COPD: Insights from COPDGene.

Ragland MF, Benway CJ, Lutz SM, Bowler RP, Hecker J, Hokanson JE, Crapo JD, Castaldi PJ, DeMeo DL, Hersh CP, Hobbs BD, Lange C, Beaty TH, Cho MH, Silverman EK.

Am J Respir Crit Care Med. 2019 Mar 25. doi: 10.1164/rccm.201808-1455SO. [Epub ahead of print]

PMID:
30908940
3.

Assessing pleiotropy and mediation in genetic loci associated with chronic obstructive pulmonary disease.

Parker MM, Lutz SM, Hobbs BD, Busch R, McDonald MN, Castaldi PJ, Beaty TH, Hokanson JE, Silverman EK, Cho MH.

Genet Epidemiol. 2019 Apr;43(3):318-329. doi: 10.1002/gepi.22192. Epub 2019 Feb 11.

PMID:
30740764
4.

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use.

Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X; 23andMe Research Team; HUNT All-In Psychiatry, Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunter DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Loukola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková A, Stefansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Munafò MR, Saccone NL, Willer CJ, Cornelis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S.

Nat Genet. 2019 Feb;51(2):237-244. doi: 10.1038/s41588-018-0307-5. Epub 2019 Jan 14.

5.

Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype.

Sordillo JE, McGeachie M, Lutz SM, Lasky-Su J, Tantisira K, Tsai CH, Dahlin A, Kelly R, Wu AC.

Pediatr Pulmonol. 2019 Feb;54(2):158-164. doi: 10.1002/ppul.24219. Epub 2018 Dec 25.

PMID:
30585438
6.

Coronary Artery Calcium on Noncontrast Thoracic Computerized Tomography Scans and All-Cause Mortality.

Budoff MJ, Lutz SM, Kinney GL, Young KA, Hokanson JE, Barr RG, Steiner R, Nath H, Lopez-Garcia C, Duca LM, Rahmani S, Osawa K, Regan EA, Li D, Casaburi R.

Circulation. 2018 Nov 20;138(21):2437-2438. doi: 10.1161/CIRCULATIONAHA.118.036835. No abstract available.

7.

Proper conditional analysis in the presence of missing data: Application to large scale meta-analysis of tobacco use phenotypes.

Jiang Y, Chen S, McGuire D, Chen F, Liu M, Iacono WG, Hewitt JK, Hokanson JE, Krauter K, Laakso M, Li KW, Lutz SM, McGue M, Pandit A, Zajac GJM, Boehnke M, Abecasis GR, Vrieze SI, Zhan X, Jiang B, Liu DJ.

PLoS Genet. 2018 Jul 17;14(7):e1007452. doi: 10.1371/journal.pgen.1007452. eCollection 2018 Jul.

8.

Identification of Chronic Obstructive Pulmonary Disease Axes That Predict All-Cause Mortality: The COPDGene Study.

Kinney GL, Santorico SA, Young KA, Cho MH, Castaldi PJ, San José Estépar R, Ross JC, Dy JG, Make BJ, Regan EA, Lynch DA, Everett DC, Lutz SM, Silverman EK, Washko GR, Crapo JD, Hokanson JE; COPDGene Investigators.

Am J Epidemiol. 2018 Oct 1;187(10):2109-2116. doi: 10.1093/aje/kwy087.

PMID:
29771274
9.

Common and Rare Variants Genetic Association Analysis of Cigarettes per Day Among Ever-Smokers in Chronic Obstructive Pulmonary Disease Cases and Controls.

Lutz SM, Frederiksen B, Begum F, McDonald MN, Cho MH, Hobbs BD, Parker MM, DeMeo DL, Hersh CP, Ehringer MA, Young K, Jiang L, Foreman MG, Kinney GL, Make BJ, Lomas DA, Bakke P, Gulsvik A, Crapo JD, Silverman EK, Beaty TH, Hokanson JE; ECLIPSE and COPDGene Investigators.

Nicotine Tob Res. 2019 May 21;21(6):714-722. doi: 10.1093/ntr/nty095.

10.

Is the Fagerström test for nicotine dependence invariant across secular trends in smoking? A question for cross-birth cohort analysis of nicotine dependence.

Glasheen C, Johnson EO, Saccone NL, Lutz SM, Baker TB, McNeil DW, Marazita ML, Hokanson JE, Bierut LJ, Hancock DB.

Drug Alcohol Depend. 2018 Apr 1;185:127-132. doi: 10.1016/j.drugalcdep.2017.12.013. Epub 2018 Feb 6.

11.

Smoking duration alone provides stronger risk estimates of chronic obstructive pulmonary disease than pack-years.

Bhatt SP, Kim YI, Harrington KF, Hokanson JE, Lutz SM, Cho MH, DeMeo DL, Wells JM, Make BJ, Rennard SI, Washko GR, Foreman MG, Tashkin DP, Wise RA, Dransfield MT, Bailey WC; COPDGene Investigators.

Thorax. 2018 May;73(5):414-421. doi: 10.1136/thoraxjnl-2017-210722. Epub 2018 Jan 11.

12.

Chest computed tomography-derived low fat-free mass index and mortality in COPD.

McDonald MN, Diaz AA, Rutten E, Lutz SM, Harmouche R, San Jose Estepar R, Kinney G, Hokanson JE, Gower BA, Wouters EFM, Rennard SI, Hersh CP, Casaburi R, Dransfield MT, Silverman EK, Washko GR.

Eur Respir J. 2017 Dec 14;50(6). pii: 1701134. doi: 10.1183/13993003.01134-2017. Print 2017 Dec.

13.

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.

Hancock DB, Guo Y, Reginsson GW, Gaddis NC, Lutz SM, Sherva R, Loukola A, Minica CC, Markunas CA, Han Y, Young KA, Gudbjartsson DF, Gu F, McNeil DW, Qaiser B, Glasheen C, Olson S, Landi MT, Madden PAF, Farrer LA, Vink J, Saccone NL, Neale MC, Kranzler HR, McKay J, Hung RJ, Amos CI, Marazita ML, Boomsma DI, Baker TB, Gelernter J, Kaprio J, Caporaso NE, Thorgeirsson TE, Hokanson JE, Bierut LJ, Stefansson K, Johnson EO.

Mol Psychiatry. 2018 Sep;23(9):1911-1919. doi: 10.1038/mp.2017.193. Epub 2017 Oct 3.

14.

Examining the role of unmeasured confounding in mediation analysis with genetic and genomic applications.

Lutz SM, Thwing A, Schmiege S, Kroehl M, Baker CD, Starling AP, Hokanson JE, Ghosh D.

BMC Bioinformatics. 2017 Jul 19;18(1):344. doi: 10.1186/s12859-017-1749-y.

15.

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

McKay JD, Hung RJ, Han Y, Zong X, Carreras-Torres R, Christiani DC, Caporaso NE, Johansson M, Xiao X, Li Y, Byun J, Dunning A, Pooley KA, Qian DC, Ji X, Liu G, Timofeeva MN, Bojesen SE, Wu X, Le Marchand L, Albanes D, Bickeböller H, Aldrich MC, Bush WS, Tardon A, Rennert G, Teare MD, Field JK, Kiemeney LA, Lazarus P, Haugen A, Lam S, Schabath MB, Andrew AS, Shen H, Hong YC, Yuan JM, Bertazzi PA, Pesatori AC, Ye Y, Diao N, Su L, Zhang R, Brhane Y, Leighl N, Johansen JS, Mellemgaard A, Saliba W, Haiman CA, Wilkens LR, Fernandez-Somoano A, Fernandez-Tardon G, van der Heijden HFM, Kim JH, Dai J, Hu Z, Davies MPA, Marcus MW, Brunnström H, Manjer J, Melander O, Muller DC, Overvad K, Trichopoulou A, Tumino R, Doherty JA, Barnett MP, Chen C, Goodman GE, Cox A, Taylor F, Woll P, Brüske I, Wichmann HE, Manz J, Muley TR, Risch A, Rosenberger A, Grankvist K, Johansson M, Shepherd FA, Tsao MS, Arnold SM, Haura EB, Bolca C, Holcatova I, Janout V, Kontic M, Lissowska J, Mukeria A, Ognjanovic S, Orlowski TM, Scelo G, Swiatkowska B, Zaridze D, Bakke P, Skaug V, Zienolddiny S, Duell EJ, Butler LM, Koh WP, Gao YT, Houlston RS, McLaughlin J, Stevens VL, Joubert P, Lamontagne M, Nickle DC, Obeidat M, Timens W, Zhu B, Song L, Kachuri L, Artigas MS, Tobin MD, Wain LV; SpiroMeta Consortium, Rafnar T, Thorgeirsson TE, Reginsson GW, Stefansson K, Hancock DB, Bierut LJ, Spitz MR, Gaddis NC, Lutz SM, Gu F, Johnson EO, Kamal A, Pikielny C, Zhu D, Lindströem S, Jiang X, Tyndale RF, Chenevix-Trench G, Beesley J, Bossé Y, Chanock S, Brennan P, Landi MT, Amos CI.

Nat Genet. 2017 Jul;49(7):1126-1132. doi: 10.1038/ng.3892. Epub 2017 Jun 12.

16.

Genetic correlation between smoking behaviors and schizophrenia.

Hartz SM, Horton AC, Hancock DB, Baker TB, Caporaso NE, Chen LS, Hokanson JE, Lutz SM, Marazita ML, McNeil DW, Pato CN, Pato MT, Johnson EO, Bierut LJ.

Schizophr Res. 2018 Apr;194:86-90. doi: 10.1016/j.schres.2017.02.022. Epub 2017 Mar 8.

17.

Gene-based segregation method for identifying rare variants in family-based sequencing studies.

Qiao D, Lange C, Laird NM, Won S, Hersh CP, Morrow J, Hobbs BD, Lutz SM, Ruczinski I, Beaty TH, Silverman EK, Cho MH.

Genet Epidemiol. 2017 May;41(4):309-319. doi: 10.1002/gepi.22037. Epub 2017 Feb 13.

18.

A general approach to testing for pleiotropy with rare and common variants.

Lutz SM, Fingerlin TE, Hokanson JE, Lange C.

Genet Epidemiol. 2017 Feb;41(2):163-170. doi: 10.1002/gepi.22011. Epub 2016 Nov 30.

19.

Pulmonary Predictors of Incident Diabetes in Smokers.

Kinney GL, Baker EH, Klein OL, Black-Shinn JL, Wan ES, Make B, Regan E, Bowler RP, Lutz SM, Young KA, Duca LM, Washko GR, Silverman EK, Crapo JD, Hokanson JE.

Chronic Obstr Pulm Dis. 2016;3(4):739-747.

20.

Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study.

Begum F, Ruczinski I, Hokanson JE, Lutz SM, Parker MM, Cho MH, Hetmanski JB, Scharpf RB, Crapo JD, Silverman EK, Beaty TH.

PLoS One. 2016 Oct 6;11(10):e0164134. doi: 10.1371/journal.pone.0164134. eCollection 2016.

21.

Genome-Wide Association Study of the Genetic Determinants of Emphysema Distribution.

Boueiz A, Lutz SM, Cho MH, Hersh CP, Bowler RP, Washko GR, Halper-Stromberg E, Bakke P, Gulsvik A, Laird NM, Beaty TH, Coxson HO, Crapo JD, Silverman EK, Castaldi PJ, DeMeo DL; COPDGene and ECLIPSE Investigators.

Am J Respir Crit Care Med. 2017 Mar 15;195(6):757-771. doi: 10.1164/rccm.201605-0997OC.

22.

Examination of the Involvement of Cholinergic-Associated Genes in Nicotine Behaviors in European and African Americans.

Melroy-Greif WE, Simonson MA, Corley RP, Lutz SM, Hokanson JE, Ehringer MA.

Nicotine Tob Res. 2017 Apr 1;19(4):417-425. doi: 10.1093/ntr/ntw200.

23.

A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.

Lutz SM, Cho MH, Young K, Hersh CP, Castaldi PJ, McDonald ML, Regan E, Mattheisen M, DeMeo DL, Parker M, Foreman M, Make BJ, Jensen RL, Casaburi R, Lomas DA, Bhatt SP, Bakke P, Gulsvik A, Crapo JD, Beaty TH, Laird NM, Lange C, Hokanson JE, Silverman EK; ECLIPSE Investigators; COPDGene Investigators.

BMC Genet. 2015 Dec 3;16:138. doi: 10.1186/s12863-015-0299-4.

24.

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.

Hancock DB, Reginsson GW, Gaddis NC, Chen X, Saccone NL, Lutz SM, Qaiser B, Sherva R, Steinberg S, Zink F, Stacey SN, Glasheen C, Chen J, Gu F, Frederiksen BN, Loukola A, Gudbjartsson DF, Brüske I, Landi MT, Bickeböller H, Madden P, Farrer L, Kaprio J, Kranzler HR, Gelernter J, Baker TB, Kraft P, Amos CI, Caporaso NE, Hokanson JE, Bierut LJ, Thorgeirsson TE, Johnson EO, Stefansson K.

Transl Psychiatry. 2015 Oct 6;5:e651. doi: 10.1038/tp.2015.149.

25.

Measuring and mitigating agricultural greenhouse gas production in the US Great Plains, 1870-2000.

Parton WJ, Gutmann MP, Merchant ER, Hartman MD, Adler PR, McNeal FM, Lutz SM.

Proc Natl Acad Sci U S A. 2015 Aug 25;112(34):E4681-8. doi: 10.1073/pnas.1416499112. Epub 2015 Aug 3.

26.

Comorbidities of COPD have a major impact on clinical outcomes, particularly in African Americans.

Putcha N, Han MK, Martinez CH, Foreman MG, Anzueto AR, Casaburi R, Cho MH, Hanania NA, Hersh CP, Kinney GL, Make BJ, Steiner RM, Lutz SM, Thomashow BM, Williams AA, Bhatt SP, Beaty TH, Bowler RP, Ramsdell JW, Curtis JL, Everett D, Hokanson JE, Lynch DA, Sutherland ER, Silverman EK, Crapo JD, Wise RA, Regan EA, Hansel NN; the COPDGene® Investigators.

Chronic Obstr Pulm Dis. 2014;1(1):105-114.

27.

Genetic influences on smoking and clinical disease. Understanding behavioral and biological pathways with mediation analysis.

Lutz SM, Hokanson JE.

Ann Am Thorac Soc. 2014 Sep;11(7):1082-3. doi: 10.1513/AnnalsATS.201407-315ED. No abstract available.

28.

Association between occupational exposure and lung function, respiratory symptoms, and high-resolution computed tomography imaging in COPDGene.

Marchetti N, Garshick E, Kinney GL, McKenzie A, Stinson D, Lutz SM, Lynch DA, Criner GJ, Silverman EK, Crapo JD; COPDGene Investigators.

Am J Respir Crit Care Med. 2014 Oct 1;190(7):756-62. doi: 10.1164/rccm.201403-0493OC.

29.

An alternative hypothesis testing strategy for secondary phenotype data in case-control genetic association studies.

Lutz SM, Hokanson JE, Lange C.

Front Genet. 2014 Jul 1;5:188. doi: 10.3389/fgene.2014.00188. eCollection 2014.

30.

Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease.

McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard SI, Wouters EF, Bakke P, Tal-Singer R, Miller BE, Gulsvik A, Casaburi R, Wells JM, Regan EA, Make BJ, Hokanson JE, Lange C, Crapo JD, Beaty TH, Silverman EK, Hersh CP; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints and COPDGene Investigators.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):678-87. doi: 10.1165/rcmb.2014-0135OC.

31.

Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema.

Castaldi PJ, Dy J, Ross J, Chang Y, Washko GR, Curran-Everett D, Williams A, Lynch DA, Make BJ, Crapo JD, Bowler RP, Regan EA, Hokanson JE, Kinney GL, Han MK, Soler X, Ramsdell JW, Barr RG, Foreman M, van Beek E, Casaburi R, Criner GJ, Lutz SM, Rennard SI, Santorico S, Sciurba FC, DeMeo DL, Hersh CP, Silverman EK, Cho MH.

Thorax. 2014 May;69(5):415-22. doi: 10.1136/thoraxjnl-2013-203601. Epub 2014 Feb 21.

32.

Quantitative computed tomography measures of pectoralis muscle area and disease severity in chronic obstructive pulmonary disease. A cross-sectional study.

McDonald ML, Diaz AA, Ross JC, San Jose Estepar R, Zhou L, Regan EA, Eckbo E, Muralidhar N, Come CE, Cho MH, Hersh CP, Lange C, Wouters E, Casaburi RH, Coxson HO, Macnee W, Rennard SI, Lomas DA, Agusti A, Celli BR, Black-Shinn JL, Kinney GL, Lutz SM, Hokanson JE, Silverman EK, Washko GR.

Ann Am Thorac Soc. 2014 Mar;11(3):326-34. doi: 10.1513/AnnalsATS.201307-229OC.

33.

Testing for direct genetic effects using a screening step in family-based association studies.

Lutz SM, Vansteelandt S, Lange C.

Front Genet. 2013 Nov 21;4:243. doi: 10.3389/fgene.2013.00243. eCollection 2013.

34.

Statistical Approaches to Combine Genetic Association Data.

Lutz SM, Fingerlin T, Fardo DW.

J Biom Biostat. 2013 Jun 1;4(3):1000166.

35.

Impact of historical land-use changes on greenhouse gas exchange in the U.S. Great Plains, 1883-2003.

Hartman MD, Merchant ER, Parton WJ, Gutmann MP, Lutz SM, Williams SA.

Ecol Appl. 2011 Jun;21(4):1105-19.

PMID:
21774417
36.

Allelic heterogeneity in LINE-1 retrotransposition activity.

Lutz SM, Vincent BJ, Kazazian HH Jr, Batzer MA, Moran JV.

Am J Hum Genet. 2003 Dec;73(6):1431-7. Epub 2003 Nov 7.

37.

A maize acetyl-coenzyme A carboxylase cDNA sequence.

Egli MA, Lutz SM, Somers DA, Gengenbach BG.

Plant Physiol. 1995 Jul;108(3):1299-300. No abstract available.

38.

Method for identifying differences between existing food intake patterns and patterns that meet nutrition recommendations.

Cleveland LE, Escobar AJ, Lutz SM, Welsh SO.

J Am Diet Assoc. 1993 May;93(5):556-60, 563.

PMID:
8315166

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