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Items: 27


The E3 Ubiquitin Ligase Asb2α in T Helper 2 Cells Negatively Regulates Antitumor Immunity in Colorectal Cancer.

Spinner CA, Lamsoul I, Métais A, Febrissy C, Moog-Lutz C, Lutz PG.

Cancer Immunol Res. 2019 Aug;7(8):1332-1344. doi: 10.1158/2326-6066.CIR-18-0562. Epub 2019 Jun 7.


Asb2α-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development.

Métais A, Lamsoul I, Melet A, Uttenweiler-Joseph S, Poincloux R, Stefanovic S, Valière A, Gonzalez de Peredo A, Stella A, Burlet-Schiltz O, Zaffran S, Lutz PG, Moog-Lutz C.

Circ Res. 2018 Mar 16;122(6):e34-e48. doi: 10.1161/CIRCRESAHA.117.312015. Epub 2018 Jan 26.


Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells.

Spinner CA, Uttenweiler-Joseph S, Metais A, Stella A, Burlet-Schiltz O, Moog-Lutz C, Lamsoul I, Lutz PG.

Sci Rep. 2015 Nov 5;5:16269. doi: 10.1038/srep16269.


Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

Lamsoul I, Uttenweiler-Joseph S, Moog-Lutz C, Lutz PG.

Biochimie. 2016 Mar;122:339-47. doi: 10.1016/j.biochi.2015.08.003. Epub 2015 Aug 4. Review.


Phosphorylation of serine 323 of ASB2α is pivotal for the targeting of filamin A to degradation.

Zakaria R, Lamsoul I, Uttenweiler-Joseph S, Erard M, Monsarrat B, Burlet-Schiltz O, Moog-Lutz C, Lutz PG.

Cell Signal. 2013 Dec;25(12):2823-30. doi: 10.1016/j.cellsig.2013.09.011. Epub 2013 Sep 15.


ASB2α regulates migration of immature dendritic cells.

Lamsoul I, Métais A, Gouot E, Heuzé ML, Lennon-Duménil AM, Moog-Lutz C, Lutz PG.

Blood. 2013 Jul 25;122(4):533-41. doi: 10.1182/blood-2012-11-466649. Epub 2013 Apr 30.


Quantitative proteomic analysis to decipher the differential apoptotic response of bortezomib-treated APL cells before and after retinoic acid differentiation reveals involvement of protein toxicity mechanisms.

Uttenweiler-Joseph S, Bouyssié D, Calligaris D, Lutz PG, Monsarrat B, Burlet-Schiltz O.

Proteomics. 2013 Jan;13(1):37-47. doi: 10.1002/pmic.201200233. Epub 2012 Dec 4.


Filamins but not Janus kinases are substrates of the ASB2α cullin-ring E3 ubiquitin ligase in hematopoietic cells.

Lamsoul I, Erard M, van der Ven PF, Lutz PG.

PLoS One. 2012;7(8):e43798. doi: 10.1371/journal.pone.0043798. Epub 2012 Aug 20.


Macrophage mesenchymal migration requires podosome stabilization by filamin A.

Guiet R, Vérollet C, Lamsoul I, Cougoule C, Poincloux R, Labrousse A, Calderwood DA, Glogauer M, Lutz PG, Maridonneau-Parini I.

J Biol Chem. 2012 Apr 13;287(16):13051-62. doi: 10.1074/jbc.M111.307124. Epub 2012 Feb 9.


The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain.

Razinia Z, Baldassarre M, Bouaouina M, Lamsoul I, Lutz PG, Calderwood DA.

J Cell Sci. 2011 Aug 1;124(Pt 15):2631-41. doi: 10.1242/jcs.084343. Epub 2011 Jul 12.


Functional and structural insights into ASB2alpha, a novel regulator of integrin-dependent adhesion of hematopoietic cells.

Lamsoul I, Burande CF, Razinia Z, Houles TC, Menoret D, Baldassarre M, Erard M, Moog-Lutz C, Calderwood DA, Lutz PG.

J Biol Chem. 2011 Sep 2;286(35):30571-81. doi: 10.1074/jbc.M111.220921. Epub 2011 Jul 7.


Filamins regulate cell spreading and initiation of cell migration.

Baldassarre M, Razinia Z, Burande CF, Lamsoul I, Lutz PG, Calderwood DA.

PLoS One. 2009 Nov 13;4(11):e7830. doi: 10.1371/journal.pone.0007830.


A label-free quantitative proteomics strategy to identify E3 ubiquitin ligase substrates targeted to proteasome degradation.

Burande CF, Heuzé ML, Lamsoul I, Monsarrat B, Uttenweiler-Joseph S, Lutz PG.

Mol Cell Proteomics. 2009 Jul;8(7):1719-27. doi: 10.1074/mcp.M800410-MCP200. Epub 2009 Apr 17.


The E3 ubiquitin ligase specificity subunit ASB2beta is a novel regulator of muscle differentiation that targets filamin B to proteasomal degradation.

Bello NF, Lamsoul I, Heuzé ML, Métais A, Moreaux G, Calderwood DA, Duprez D, Moog-Lutz C, Lutz PG.

Cell Death Differ. 2009 Jun;16(6):921-32. doi: 10.1038/cdd.2009.27. Epub 2009 Mar 20.


JAM-L-mediated leukocyte adhesion to endothelial cells is regulated in cis by alpha4beta1 integrin activation.

Luissint AC, Lutz PG, Calderwood DA, Couraud PO, Bourdoulous S.

J Cell Biol. 2008 Dec 15;183(6):1159-73. doi: 10.1083/jcb.200805061. Epub 2008 Dec 8.


ASB2 targets filamins A and B to proteasomal degradation.

Heuzé ML, Lamsoul I, Baldassarre M, Lad Y, Lévêque S, Razinia Z, Moog-Lutz C, Calderwood DA, Lutz PG.

Blood. 2008 Dec 15;112(13):5130-40. doi: 10.1182/blood-2007-12-128744. Epub 2008 Sep 17.


Ubiquitin-mediated proteasomal degradation in normal and malignant hematopoiesis.

Heuzé ML, Lamsoul I, Moog-Lutz C, Lutz PG.

Blood Cells Mol Dis. 2008 Mar-Apr;40(2):200-10. Epub 2007 Oct 4. Review.


PRAM-1 potentiates arsenic trioxide-induced JNK activation.

Denis FM, Benecke A, Di Gioia Y, Touw IP, Cayre YE, Lutz PG.

J Biol Chem. 2005 Mar 11;280(10):9043-8. Epub 2005 Jan 6.


ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.

Heuzé ML, Guibal FC, Banks CA, Conaway JW, Conaway RC, Cayre YE, Benecke A, Lutz PG.

J Biol Chem. 2005 Feb 18;280(7):5468-74. Epub 2004 Dec 8.


JAML, a novel protein with characteristics of a junctional adhesion molecule, is induced during differentiation of myeloid leukemia cells.

Moog-Lutz C, Cavé-Riant F, Guibal FC, Breau MA, Di Gioia Y, Couraud PO, Cayre YE, Bourdoulous S, Lutz PG.

Blood. 2003 Nov 1;102(9):3371-8. Epub 2003 Jul 17.


Signaling revisited in acute promyelocytic leukemia.

Lutz PG, Moog-Lutz C, Cayre YE.

Leukemia. 2002 Oct;16(10):1933-9. Review.


ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells.

Guibal FC, Moog-Lutz C, Smolewski P, Di Gioia Y, Darzynkiewicz Z, Lutz PG, Cayre YE.

J Biol Chem. 2002 Jan 4;277(1):218-24. Epub 2001 Oct 26.


PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.

Moog-Lutz C, Peterson EJ, Lutz PG, Eliason S, Cavé-Riant F, Singer A, Di Gioia Y, Dmowski S, Kamens J, Cayre YE, Koretzky G.

J Biol Chem. 2001 Jun 22;276(25):22375-81. Epub 2001 Apr 11.


Myeloblastin is an Myb target gene: mechanisms of regulation in myeloid leukemia cells growth-arrested by retinoic acid.

Lutz PG, Houzel-Charavel A, Moog-Lutz C, Cayre YE.

Blood. 2001 Apr 15;97(8):2449-56.


Myeloblastin is a granulocyte colony-stimulating factor-responsive gene conferring factor-independent growth to hematopoietic cells.

Lutz PG, Moog-Lutz C, Coumau-Gatbois E, Kobari L, Di Gioia Y, Cayre YE.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1601-6.


Human milk lipids. 3. Short-term effects of dietary carbohydrate and fat.

Read WW, Lutz PG, Tashjian A.

Am J Clin Nutr. 1965 Sep;17(3):184-7. No abstract available.


Human milk lipids. II. The influence of dietary carbohydrates and fat on the fatty acids of mature milk. A study in four ethnic groups.

Read WW, Lutz PG, Tashjian A.

Am J Clin Nutr. 1965 Sep;17(3):180-3. No abstract available.


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