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Items: 1 to 50 of 104

1.

Extracellular vesicles from mature dendritic cells (DC) differentiate monocytes into immature DC.

Schierer S, Ostalecki C, Zinser E, Lamprecht R, Plosnita B, Stich L, Dörrie J, Lutz MB, Schuler G, Baur AS.

Life Sci Alliance. 2018 Dec 3;1(6):e201800093. doi: 10.26508/lsa.201800093. eCollection 2018 Dec.

2.

High-grade glioma associated immunosuppression does not prevent immune responses induced by therapeutic vaccines in combination with Treg depletion.

Löhr M, Freitag B, Technau A, Krauss J, Monoranu CM, Rachor J, Lutz MB, Hagemann C, Kessler AF, Linsenmann T, Wölfl M, Ernestus RI, Engelhardt S, Gelbrich G, Schlegel PG, Eyrich M.

Cancer Immunol Immunother. 2018 Oct;67(10):1545-1558. doi: 10.1007/s00262-018-2214-0. Epub 2018 Jul 27.

3.

TIGIT+ iTregs elicited by human regulatory macrophages control T cell immunity.

Riquelme P, Haarer J, Kammler A, Walter L, Tomiuk S, Ahrens N, Wege AK, Goecze I, Zecher D, Banas B, Spang R, Fändrich F, Lutz MB, Sawitzki B, Schlitt HJ, Ochando J, Geissler EK, Hutchinson JA.

Nat Commun. 2018 Jul 20;9(1):2858. doi: 10.1038/s41467-018-05167-8.

4.

Tolerogenic Transcriptional Signatures of Steady-State and Pathogen-Induced Dendritic Cells.

Vendelova E, Ashour D, Blank P, Erhard F, Saliba AE, Kalinke U, Lutz MB.

Front Immunol. 2018 Feb 28;9:333. doi: 10.3389/fimmu.2018.00333. eCollection 2018. Review.

5.

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function.

Ribechini E, Hutchinson JA, Hergovits S, Heuer M, Lucas J, Schleicher U, Jordán Garrote AL, Potter SJ, Riquelme P, Brackmann H, Müller N, Raifer H, Berberich I, Huber M, Beilhack A, Lohoff M, Bogdan C, Eyrich M, Hermanns HM, Geissler EK, Lutz MB.

Blood Adv. 2017 Jun 7;1(14):947-960. doi: 10.1182/bloodadvances.2017006858. eCollection 2017 Jun 13.

6.

Human and Murine Innate Immune Cell Populations Display Common and Distinct Response Patterns during Their In Vitro Interaction with the Pathogenic Mold Aspergillus fumigatus.

Hellmann AM, Lother J, Wurster S, Lutz MB, Schmitt AL, Morton CO, Eyrich M, Czakai K, Einsele H, Loeffler J.

Front Immunol. 2017 Dec 6;8:1716. doi: 10.3389/fimmu.2017.01716. eCollection 2017.

7.

GM-CSF Monocyte-Derived Cells and Langerhans Cells As Part of the Dendritic Cell Family.

Lutz MB, Strobl H, Schuler G, Romani N.

Front Immunol. 2017 Oct 23;8:1388. doi: 10.3389/fimmu.2017.01388. eCollection 2017. Review.

8.

Low doses of cholera toxin and its mediator cAMP induce CTLA-2 secretion by dendritic cells to enhance regulatory T cell conversion.

Silva-Vilches C, Pletinckx K, Lohnert M, Pavlovic V, Ashour D, John V, Vendelova E, Kneitz S, Zhou J, Chen R, Reinheckel T, Mueller TD, Bodem J, Lutz MB.

PLoS One. 2017 Jul 31;12(7):e0178114. doi: 10.1371/journal.pone.0178114. eCollection 2017.

9.

RelB+ Steady-State Migratory Dendritic Cells Control the Peripheral Pool of the Natural Foxp3+ Regulatory T Cells.

Döhler A, Schneider T, Eckert I, Ribechini E, Andreas N, Riemann M, Reizis B, Weih F, Lutz MB.

Front Immunol. 2017 Jun 22;8:726. doi: 10.3389/fimmu.2017.00726. eCollection 2017.

10.

Phenotypically resembling myeloid derived suppressor cells are increased in children with HIV and exposed/infected with Mycobacterium tuberculosis.

Du Plessis N, Jacobs R, Gutschmidt A, Fang Z, van Helden PD, Lutz MB, Hesseling AC, Walzl G.

Eur J Immunol. 2017 Jan;47(1):107-118. doi: 10.1002/eji.201646658. Epub 2016 Dec 16.

11.

Proteomic Analysis of Excretory-Secretory Products of Mesocestoides corti Metacestodes Reveals Potential Suppressors of Dendritic Cell Functions.

Vendelova E, Camargo de Lima J, Lorenzatto KR, Monteiro KM, Mueller T, Veepaschit J, Grimm C, Brehm K, Hrčková G, Lutz MB, Ferreira HB, Nono JK.

PLoS Negl Trop Dis. 2016 Oct 13;10(10):e0005061. doi: 10.1371/journal.pntd.0005061. eCollection 2016 Oct.

12.

Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages - a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape.

Montalbán Del Barrio I, Penski C, Schlahsa L, Stein RG, Diessner J, Wöckel A, Dietl J, Lutz MB, Mittelbronn M, Wischhusen J, Häusler SFM.

J Immunother Cancer. 2016 Aug 16;4:49. doi: 10.1186/s40425-016-0154-9. eCollection 2016.

13.

Exogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.

Chopra M, Biehl M, Steinfatt T, Brandl A, Kums J, Amich J, Vaeth M, Kuen J, Holtappels R, Podlech J, Mottok A, Kraus S, Jordán-Garrote AL, Bäuerlein CA, Brede C, Ribechini E, Fick A, Seher A, Polz J, Ottmüller KJ, Baker J, Nishikii H, Ritz M, Mattenheimer K, Schwinn S, Winter T, Schäfer V, Krappmann S, Einsele H, Müller TD, Reddehase MJ, Lutz MB, Männel DN, Berberich-Siebelt F, Wajant H, Beilhack A.

J Exp Med. 2016 Aug 22;213(9):1881-900. doi: 10.1084/jem.20151563. Epub 2016 Aug 15.

14.
15.

Induction of CD4(+) Regulatory and Polarized Effector/helper T Cells by Dendritic Cells.

Lutz MB.

Immune Netw. 2016 Feb;16(1):13-25. doi: 10.4110/in.2016.16.1.13. Epub 2016 Feb 25. Review.

16.

Still Alive and Kicking: In-Vitro-Generated GM-CSF Dendritic Cells!

Lutz MB, Inaba K, Schuler G, Romani N.

Immunity. 2016 Jan 19;44(1):1-2. doi: 10.1016/j.immuni.2015.12.013. No abstract available.

17.

Sialoadhesin promotes neuroinflammation-related disease progression in two mouse models of CLN disease.

Groh J, Ribechini E, Stadler D, Schilling T, Lutz MB, Martini R.

Glia. 2016 May;64(5):792-809. doi: 10.1002/glia.22962. Epub 2016 Jan 17.

PMID:
26775238
18.

CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice.

Milanez-Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Lutz MB, Schultze JL, Huehn J.

Eur J Microbiol Immunol (Bp). 2015 Nov 4;5(4):246-55. doi: 10.1556/1886.2015.00038. eCollection 2015 Dec.

19.

Deficiency of HIF1α in Antigen-Presenting Cells Aggravates Atherosclerosis and Type 1 T-Helper Cell Responses in Mice.

Chaudhari SM, Sluimer JC, Koch M, Theelen TL, Manthey HD, Busch M, Caballero-Franco C, Vogel F, Cochain C, Pelisek J, Daemen MJ, Lutz MB, Görlach A, Kissler S, Hermanns HM, Zernecke A.

Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2316-25. doi: 10.1161/ATVBAHA.115.306171. Epub 2015 Sep 24.

20.

Immunity and immune modulation elicited by the larval cestode Mesocestoides vogae and its products.

Vendelova E, Lutz MB, Hrčková G.

Parasite Immunol. 2015 Oct;37(10):493-504. doi: 10.1111/pim.12216.

21.

In vitro-generated MDSCs prevent murine GVHD by inducing type 2 T cells without disabling antitumor cytotoxicity.

Messmann JJ, Reisser T, Leithäuser F, Lutz MB, Debatin KM, Strauss G.

Blood. 2015 Aug 27;126(9):1138-48. doi: 10.1182/blood-2015-01-624163. Epub 2015 Jul 16.

22.

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

Vogel SZ, Schlickeiser S, Jürchott K, Akyuez L, Schumann J, Appelt C, Vogt K, Schröder M, Vaeth M, Berberich-Siebelt F, Lutz MB, Grütz G, Sawitzki B.

J Immunol. 2015 Apr 1;194(7):3136-46. doi: 10.4049/jimmunol.1400713. Epub 2015 Mar 6.

23.

Immature dendritic cells convert anergic nonregulatory T cells into Foxp3- IL-10+ regulatory T cells by engaging CD28 and CTLA-4.

Pletinckx K, Vaeth M, Schneider T, Beyersdorf N, Hünig T, Berberich-Siebelt F, Lutz MB.

Eur J Immunol. 2015 Feb;45(2):480-91. doi: 10.1002/eji.201444991. Epub 2014 Dec 2.

24.

Cathepsin B in antigen-presenting cells controls mediators of the Th1 immune response during Leishmania major infection.

Gonzalez-Leal IJ, Röger B, Schwarz A, Schirmeister T, Reinheckel T, Lutz MB, Moll H.

PLoS Negl Trop Dis. 2014 Sep 25;8(9):e3194. doi: 10.1371/journal.pntd.0003194. eCollection 2014 Sep.

25.

Immunogenic and tolerogenic effects of the chimeric IL-2-diphtheria toxin cytocidal agent Ontak® on CD25+ cells.

Lutz MB, Baur AS, Schuler-Thurner B, Schuler G.

Oncoimmunology. 2014 Mar 17;3:e28223. eCollection 2014.

26.

Development and validation of a fully GMP-compliant production process of autologous, tumor-lysate-pulsed dendritic cells.

Eyrich M, Schreiber SC, Rachor J, Krauss J, Pauwels F, Hain J, Wölfl M, Lutz MB, de Vleeschouwer S, Schlegel PG, Van Gool SW.

Cytotherapy. 2014 Jul;16(7):946-64. doi: 10.1016/j.jcyt.2014.02.017. Epub 2014 May 13.

PMID:
24831836
27.

The nature of activatory and tolerogenic dendritic cell-derived signal 2.

Granucci F, Lutz MB, Zanoni I.

Front Immunol. 2014 Feb 6;5:42. doi: 10.3389/fimmu.2014.00042. eCollection 2014. No abstract available.

28.

Dendritic cell subset distributions in the aorta in healthy and atherosclerotic mice.

Busch M, Westhofen TC, Koch M, Lutz MB, Zernecke A.

PLoS One. 2014 Feb 14;9(2):e88452. doi: 10.1371/journal.pone.0088452. eCollection 2014.

29.

EmTIP, a T-Cell immunomodulatory protein secreted by the tapeworm Echinococcus multilocularis is important for early metacestode development.

Nono JK, Lutz MB, Brehm K.

PLoS Negl Trop Dis. 2014 Jan 2;8(1):e2632. doi: 10.1371/journal.pntd.0002632. eCollection 2014.

30.

Dendritic cells generated with Flt3L and exposed to apoptotic cells lack induction of T cell anergy and Foxp3⁺ regulatory T cell conversion in vitro.

Pletinckx K, Lutz MB.

Immunobiology. 2014 Mar;219(3):230-40. doi: 10.1016/j.imbio.2013.10.006. Epub 2013 Oct 24.

PMID:
24252473
31.
32.

Denileukin diftitox (ONTAK) induces a tolerogenic phenotype in dendritic cells and stimulates survival of resting Treg.

Baur AS, Lutz MB, Schierer S, Beltrame L, Theiner G, Zinser E, Ostalecki C, Heidkamp G, Haendle I, Erdmann M, Wiesinger M, Leisgang W, Gross S, Pommer AJ, Kämpgen E, Dudziak D, Steinkasserer A, Cavalieri D, Schuler-Thurner B, Schuler G.

Blood. 2013 Sep 26;122(13):2185-94. doi: 10.1182/blood-2012-09-456988. Epub 2013 Aug 19.

33.

Increased frequency of myeloid-derived suppressor cells during active tuberculosis and after recent mycobacterium tuberculosis infection suppresses T-cell function.

du Plessis N, Loebenberg L, Kriel M, von Groote-Bidlingmaier F, Ribechini E, Loxton AG, van Helden PD, Lutz MB, Walzl G.

Am J Respir Crit Care Med. 2013 Sep 15;188(6):724-32. doi: 10.1164/rccm.201302-0249OC.

PMID:
23885784
34.

The nature of activatory and tolerogenic dendritic cell-derived signal 2.

Granucci F, Lutz MB, Zanoni I.

Front Immunol. 2013 Jul 16;4:198. doi: 10.3389/fimmu.2013.00198. eCollection 2013. No abstract available.

35.
36.

Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells.

Langenhorst D, Gogishvili T, Ribechini E, Kneitz S, McPherson K, Lutz MB, Hünig T.

PLoS One. 2012;7(11):e50080. doi: 10.1371/journal.pone.0050080. Epub 2012 Nov 30.

37.

Autoimmunity, dendritic cells and relevance for Parkinson's disease.

Koutsilieri E, Lutz MB, Scheller C.

J Neural Transm (Vienna). 2013 Jan;120(1):75-81. doi: 10.1007/s00702-012-0842-7. Epub 2012 Jun 15. Review.

38.

Therapeutic potential of semi-mature dendritic cells for tolerance induction.

Lutz MB.

Front Immunol. 2012 May 18;3:123. doi: 10.3389/fimmu.2012.00123. eCollection 2012.

39.

Excretory/secretory-products of Echinococcus multilocularis larvae induce apoptosis and tolerogenic properties in dendritic cells in vitro.

Nono JK, Pletinckx K, Lutz MB, Brehm K.

PLoS Negl Trop Dis. 2012;6(2):e1516. doi: 10.1371/journal.pntd.0001516. Epub 2012 Feb 21.

40.

Buy one, get one free: additional functions of GM-CSF in DC maturation.

Lutz MB.

Eur J Immunol. 2012 Jan;42(1):35-8. doi: 10.1002/eji.201142271.

41.

Neuromelanin is an immune stimulator for dendritic cells in vitro.

Oberländer U, Pletinckx K, Döhler A, Müller N, Lutz MB, Arzberger T, Riederer P, Gerlach M, Koutsilieri E, Scheller C.

BMC Neurosci. 2011 Nov 15;12:116. doi: 10.1186/1471-2202-12-116.

42.

Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses.

Pletinckx K, Stijlemans B, Pavlovic V, Laube R, Brandl C, Kneitz S, Beschin A, De Baetselier P, Lutz MB.

Eur J Immunol. 2011 Dec;41(12):3479-94. doi: 10.1002/eji.201141631. Epub 2011 Nov 3. Erratum in: Eur J Immunol. 2012 Jun;42(6):1649.

43.

CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.

Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A.

J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925.

44.

Steady state migratory RelB+ langerin+ dermal dendritic cells mediate peripheral induction of antigen-specific CD4+ CD25+ Foxp3+ regulatory T cells.

Azukizawa H, Döhler A, Kanazawa N, Nayak A, Lipp M, Malissen B, Autenrieth I, Katayama I, Riemann M, Weih F, Berberich-Siebelt F, Lutz MB.

Eur J Immunol. 2011 May;41(5):1420-34. doi: 10.1002/eji.201040930. Epub 2011 Apr 14.

45.

Role of dendritic cell maturity/costimulation for generation, homeostasis, and suppressive activity of regulatory T cells.

Pletinckx K, Döhler A, Pavlovic V, Lutz MB.

Front Immunol. 2011 Sep 27;2:39. doi: 10.3389/fimmu.2011.00039. eCollection 2011.

46.

Nomenclature of monocytes and dendritic cells in blood.

Ziegler-Heitbrock L, Ancuta P, Crowe S, Dalod M, Grau V, Hart DN, Leenen PJ, Liu YJ, MacPherson G, Randolph GJ, Scherberich J, Schmitz J, Shortman K, Sozzani S, Strobl H, Zembala M, Austyn JM, Lutz MB.

Blood. 2010 Oct 21;116(16):e74-80. doi: 10.1182/blood-2010-02-258558. Epub 2010 Jul 13.

47.

B7-H1-deficiency enhances the potential of tolerogenic dendritic cells by activating CD1d-restricted type II NKT cells.

Brandl C, Ortler S, Herrmann T, Cardell S, Lutz MB, Wiendl H.

PLoS One. 2010 May 24;5(5):e10800. doi: 10.1371/journal.pone.0010800.

48.

Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells.

Schumann K, Lämmermann T, Bruckner M, Legler DF, Polleux J, Spatz JP, Schuler G, Förster R, Lutz MB, Sorokin L, Sixt M.

Immunity. 2010 May 28;32(5):703-13. doi: 10.1016/j.immuni.2010.04.017. Epub 2010 May 13.

49.

Subsets, expansion and activation of myeloid-derived suppressor cells.

Ribechini E, Greifenberg V, Sandwick S, Lutz MB.

Med Microbiol Immunol. 2010 Aug;199(3):273-81. doi: 10.1007/s00430-010-0151-4. Epub 2010 Apr 8. Review.

PMID:
20376485
50.

Revisiting the tolerogenicity of epidermal Langerhans cells.

Lutz MB, Döhler A, Azukizawa H.

Immunol Cell Biol. 2010 May-Jun;88(4):381-6. doi: 10.1038/icb.2010.17. Epub 2010 Mar 9. Review.

PMID:
20212507

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