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Items: 1 to 50 of 95

1.

Multi-axial self-organization properties of mouse embryonic stem cells into gastruloids.

Beccari L, Moris N, Girgin M, Turner DA, Baillie-Johnson P, Cossy AC, Lutolf MP, Duboule D, Arias AM.

Nature. 2018 Oct;562(7726):272-276. doi: 10.1038/s41586-018-0578-0. Epub 2018 Oct 3.

PMID:
30283134
2.

Label-Free Quantification Proteomics for the Identification of Mesenchymal Stromal Cell Matrisome Inside 3D Poly(Ethylene Glycol) Hydrogels.

Devaud YR, Avilla-Royo E, Trachsel C, Grossmann J, Martin I, Lutolf MP, Ehrbar M.

Adv Healthc Mater. 2018 Sep 27:e1800534. doi: 10.1002/adhm.201800534. [Epub ahead of print]

PMID:
30260582
3.

Progress and potential in organoid research.

Rossi G, Manfrin A, Lutolf MP.

Nat Rev Genet. 2018 Nov;19(11):671-687. doi: 10.1038/s41576-018-0051-9. Review.

PMID:
30228295
4.

Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment.

Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P.

Acta Biomater. 2018 Feb;67:156-166. doi: 10.1016/j.actbio.2017.11.034. Epub 2017 Nov 29.

PMID:
29197579
5.

Erratum to: Generation of Induced Pluripotent Stem Cells in Defined Three-Dimensional Hydrogels.

Caiazzo M, Tabata Y, Lutolf MP.

Methods Mol Biol. 2017;1612:E1. doi: 10.1007/978-1-4939-7021-6_32. No abstract available.

PMID:
29164526
6.

Synthesis and characterization of well-defined hydrogel matrices and their application to intestinal stem cell and organoid culture.

Gjorevski N, Lutolf MP.

Nat Protoc. 2017 Nov;12(11):2263-2274. doi: 10.1038/nprot.2017.095. Epub 2017 Oct 5.

PMID:
28981121
7.

Editorial overview: Tissue, cell and pathway engineering: The advent of complexity.

Benenson Y, Lutolf MP.

Curr Opin Biotechnol. 2017 Oct;47:iv-vi. doi: 10.1016/j.copbio.2017.08.015. Epub 2017 Sep 7. No abstract available.

PMID:
28890003
8.

Single-cell analyses identify bioengineered niches for enhanced maintenance of hematopoietic stem cells.

Roch A, Giger S, Girotra M, Campos V, Vannini N, Naveiras O, Gobaa S, Lutolf MP.

Nat Commun. 2017 Aug 9;8(1):221. doi: 10.1038/s41467-017-00291-3.

9.

Decoding of position in the developing neural tube from antiparallel morphogen gradients.

Zagorski M, Tabata Y, Brandenberg N, Lutolf MP, Tkačik G, Bollenbach T, Briscoe J, Kicheva A.

Science. 2017 Jun 30;356(6345):1379-1383. doi: 10.1126/science.aam5887.

10.

Generation of Induced Pluripotent Stem Cells in Defined Three-Dimensional Hydrogels.

Caiazzo M, Tabata Y, Lutolf MP.

Methods Mol Biol. 2017;1612:65-78. doi: 10.1007/978-1-4939-7021-6_5. Erratum in: Methods Mol Biol. 2017;1612:E1.

PMID:
28634935
11.

Microfluidic Programming of Compositional Hydrogel Landscapes.

Allazetta S, Negro A, Lutolf MP.

Macromol Rapid Commun. 2017 Aug;38(15). doi: 10.1002/marc.201700255. Epub 2017 Jun 12.

PMID:
28605081
12.

Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells.

Ishihara K, Ranga A, Lutolf MP, Tanaka EM, Meinhardt A.

Methods Mol Biol. 2017;1597:43-55. doi: 10.1007/978-1-4939-6949-4_4.

PMID:
28361309
13.

Multiscale microenvironmental perturbation of pluripotent stem cell fate and self-organization.

Tabata Y, Lutolf MP.

Sci Rep. 2017 Mar 17;7:44711. doi: 10.1038/srep44711.

14.

The hope and the hype of organoid research.

Huch M, Knoblich JA, Lutolf MP, Martinez-Arias A.

Development. 2017 Mar 15;144(6):938-941. doi: 10.1242/dev.150201. Review.

15.

Designer matrices for intestinal stem cell and organoid culture.

Gjorevski N, Sachs N, Manfrin A, Giger S, Bragina ME, Ordóñez-Morán P, Clevers H, Lutolf MP.

Nature. 2016 Nov 24;539(7630):560-564. doi: 10.1038/nature20168. Epub 2016 Nov 16.

PMID:
27851739
16.

Neural tube morphogenesis in synthetic 3D microenvironments.

Ranga A, Girgin M, Meinhardt A, Eberle D, Caiazzo M, Tanaka EM, Lutolf MP.

Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6831-E6839. Epub 2016 Oct 14. Erratum in: Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):E3163.

17.

Specification of haematopoietic stem cell fate via modulation of mitochondrial activity.

Vannini N, Girotra M, Naveiras O, Nikitin G, Campos V, Giger S, Roch A, Auwerx J, Lutolf MP.

Nat Commun. 2016 Oct 12;7:13125. doi: 10.1038/ncomms13125.

18.

In Situ Patterning of Microfluidic Networks in 3D Cell-Laden Hydrogels.

Brandenberg N, Lutolf MP.

Adv Mater. 2016 Sep;28(34):7450-6. doi: 10.1002/adma.201601099. Epub 2016 Jun 23.

PMID:
27334545
19.

NAD⁺ repletion improves mitochondrial and stem cell function and enhances life span in mice.

Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, D'Amico D, Ropelle ER, Lutolf MP, Aebersold R, Schoonjans K, Menzies KJ, Auwerx J.

Science. 2016 Jun 17;352(6292):1436-43. doi: 10.1126/science.aaf2693. Epub 2016 Apr 28.

20.

Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction.

Ranga A, Lutolf MP, Hilborn J, Ossipov DA.

Biomacromolecules. 2016 May 9;17(5):1553-60. doi: 10.1021/acs.biomac.5b01587. Epub 2016 Apr 8.

PMID:
27014785
21.

Defined three-dimensional microenvironments boost induction of pluripotency.

Caiazzo M, Okawa Y, Ranga A, Piersigilli A, Tabata Y, Lutolf MP.

Nat Mater. 2016 Mar;15(3):344-52. doi: 10.1038/nmat4536. Epub 2016 Jan 11.

PMID:
26752655
22.

Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction.

Nowell CS, Odermatt PD, Azzolin L, Hohnel S, Wagner EF, Fantner GE, Lutolf MP, Barrandon Y, Piccolo S, Radtke F.

Nat Cell Biol. 2016 Feb;18(2):168-80. doi: 10.1038/ncb3290. Epub 2015 Dec 21.

PMID:
26689676
23.

Cell-Instructive Microgels with Tailor-Made Physicochemical Properties.

Allazetta S, Kolb L, Zerbib S, Bardy J, Lutolf MP.

Small. 2015 Nov 11;11(42):5647-56. doi: 10.1002/smll.201501001. Epub 2015 Sep 9.

PMID:
26349486
24.

Brief Report: Single-Cell Analysis Reveals Cell Division-Independent Emergence of Megakaryocytes From Phenotypic Hematopoietic Stem Cells.

Roch A, Trachsel V, Lutolf MP.

Stem Cells. 2015 Oct;33(10):3152-7. doi: 10.1002/stem.2106. Epub 2015 Aug 6.

25.

Capturing Cell-Cell Interactions via SNAP-tag and CLIP-tag Technology.

Hoehnel S, Lutolf MP.

Bioconjug Chem. 2015 Aug 19;26(8):1678-86. doi: 10.1021/acs.bioconjchem.5b00268. Epub 2015 Jun 26.

PMID:
26079967
26.

Stem cell niche engineering through droplet microfluidics.

Allazetta S, Lutolf MP.

Curr Opin Biotechnol. 2015 Dec;35:86-93. doi: 10.1016/j.copbio.2015.05.003. Epub 2015 Jun 4. Review.

PMID:
26051090
27.

Substrate elasticity modulates the responsiveness of mesenchymal stem cells to commitment cues.

Gobaa S, Hoehnel S, Lutolf MP.

Integr Biol (Camb). 2015 Oct;7(10):1135-42. doi: 10.1039/c4ib00176a. Epub 2015 Mar 9.

PMID:
25749492
28.

Locally controlling mesenchymal stem cell morphogenesis by 3D PDGF-BB gradients towards the establishment of an in vitro perivascular niche.

Lienemann PS, Devaud YR, Reuten R, Simona BR, Karlsson M, Weber W, Koch M, Lutolf MP, Milleret V, Ehrbar M.

Integr Biol (Camb). 2015 Jan;7(1):101-11. doi: 10.1039/c4ib00152d.

PMID:
25385042
29.

Ultra-rapid prototyping of flexible, multi-layered microfluidic devices via razor writing.

Cosson S, Aeberli LG, Brandenberg N, Lutolf MP.

Lab Chip. 2015 Jan 7;15(1):72-6. doi: 10.1039/c4lc00848k.

PMID:
25373917
30.

3D niche microarrays for systems-level analyses of cell fate.

Ranga A, Gobaa S, Okawa Y, Mosiewicz K, Negro A, Lutolf MP.

Nat Commun. 2014 Jul 14;5:4324. doi: 10.1038/ncomms5324.

31.

Bioengineering approaches to guide stem cell-based organogenesis.

Gjorevski N, Ranga A, Lutolf MP.

Development. 2014 May;141(9):1794-804. doi: 10.1242/dev.101048. Review.

32.

Hydrogel microfluidics for the patterning of pluripotent stem cells.

Cosson S, Lutolf MP.

Sci Rep. 2014 Mar 25;4:4462. doi: 10.1038/srep04462.

33.

Drug discovery through stem cell-based organoid models.

Ranga A, Gjorevski N, Lutolf MP.

Adv Drug Deliv Rev. 2014 Apr;69-70:19-28. doi: 10.1016/j.addr.2014.02.006. Epub 2014 Feb 26. Review.

PMID:
24582599
34.

Microfluidic patterning of protein gradients on biomimetic hydrogel substrates.

Cosson S, Lutolf MP.

Methods Cell Biol. 2014;121:91-102. doi: 10.1016/B978-0-12-800281-0.00007-5.

PMID:
24560505
35.

In situ cell manipulation through enzymatic hydrogel photopatterning.

Mosiewicz KA, Kolb L, van der Vlies AJ, Martino MM, Lienemann PS, Hubbell JA, Ehrbar M, Lutolf MP.

Nat Mater. 2013 Nov;12(11):1072-8. doi: 10.1038/nmat3766. Epub 2013 Oct 13.

PMID:
24121990
36.

A high-capacity cell macroencapsulation system supporting the long-term survival of genetically engineered allogeneic cells.

Lathuilière A, Cosson S, Lutolf MP, Schneider BL, Aebischer P.

Biomaterials. 2014 Jan;35(2):779-91. doi: 10.1016/j.biomaterials.2013.09.071. Epub 2013 Oct 5.

PMID:
24103654
37.

Cell specific ingrowth hydrogels.

Bracher M, Bezuidenhout D, Lutolf MP, Franz T, Sun M, Zilla P, Davies NH.

Biomaterials. 2013 Sep;34(28):6797-803. doi: 10.1016/j.biomaterials.2013.05.057. Epub 2013 Jun 15.

PMID:
23777918
38.

A generic strategy for pharmacological caging of growth factors for tissue engineering.

Karlsson M, Lienemann PS, Sprossmann N, Heilmann K, Brummer T, Lutolf MP, Ehrbar M, Weber W.

Chem Commun (Camb). 2013 Jul 7;49(53):5927-9. doi: 10.1039/c3cc41616j.

39.

Live mammalian cell arrays.

Woodruff K, Fidalgo LM, Gobaa S, Lutolf MP, Maerkl SJ.

Nat Methods. 2013 Jun;10(6):550-2. doi: 10.1038/nmeth.2473. Epub 2013 May 5.

PMID:
23644546
40.

Patterning of cell-instructive hydrogels by hydrodynamic flow focusing.

Cosson S, Allazetta S, Lutolf MP.

Lab Chip. 2013 Jun 7;13(11):2099-105. doi: 10.1039/c3lc50219h.

PMID:
23598796
41.

Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix.

Martino MM, Briquez PS, Ranga A, Lutolf MP, Hubbell JA.

Proc Natl Acad Sci U S A. 2013 Mar 19;110(12):4563-8. doi: 10.1073/pnas.1221602110. Epub 2013 Mar 4.

42.

Microfluidic synthesis of cell-type-specific artificial extracellular matrix hydrogels.

Allazetta S, Hausherr TC, Lutolf MP.

Biomacromolecules. 2013 Apr 8;14(4):1122-31. doi: 10.1021/bm4000162. Epub 2013 Mar 8.

PMID:
23439131
43.

Hydrogel Microwell Arrays Allow the Assessment of Protease-Associated Enhancement of Cancer Cell Aggregation and Survival.

Loessner D, Kobel S, Clements JA, Lutolf MP, Hutmacher DW.

Microarrays (Basel). 2013 Aug 22;2(3):208-27. doi: 10.3390/microarrays2030208.

44.

Sorting live stem cells based on Sox2 mRNA expression.

Larsson HM, Lee ST, Roccio M, Velluto D, Lutolf MP, Frey P, Hubbell JA.

PLoS One. 2012;7(11):e49874. doi: 10.1371/journal.pone.0049874. Epub 2012 Nov 27.

45.

Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.

Knobloch M, Braun SM, Zurkirchen L, von Schoultz C, Zamboni N, Araúzo-Bravo MJ, Kovacs WJ, Karalay O, Suter U, Machado RA, Roccio M, Lutolf MP, Semenkovich CF, Jessberger S.

Nature. 2013 Jan 10;493(7431):226-30. doi: 10.1038/nature11689. Epub 2012 Dec 2.

46.

Predicting stem cell fate changes by differential cell cycle progression patterns.

Roccio M, Schmitter D, Knobloch M, Okawa Y, Sage D, Lutolf MP.

Development. 2013 Jan 15;140(2):459-70. doi: 10.1242/dev.086215. Epub 2012 Nov 28.

47.

A versatile approach to engineering biomolecule-presenting cellular microenvironments.

Lienemann PS, Karlsson M, Sala A, Wischhusen HM, Weber FE, Zimmermann R, Weber W, Lutolf MP, Ehrbar M.

Adv Healthc Mater. 2013 Feb;2(2):292-6. doi: 10.1002/adhm.201200280. Epub 2012 Nov 7. No abstract available.

PMID:
23184806
48.

Controlled breast cancer microarrays for the deconvolution of cellular multilayering and density effects upon drug responses.

Håkanson M, Kobel S, Lutolf MP, Textor M, Cukierman E, Charnley M.

PLoS One. 2012;7(6):e40141. doi: 10.1371/journal.pone.0040141. Epub 2012 Jun 29.

49.

Extracellular matrix bioengineering and systems biology approaches in liver disease.

Nieto N, Lutolf MP.

Syst Synth Biol. 2011 Jun;5(1-2):11-20. doi: 10.1007/s11693-011-9085-4. Epub 2011 Jun 17.

50.

Automated analysis of single stem cells in microfluidic traps.

Kobel SA, Burri O, Griffa A, Girotra M, Seitz A, Lutolf MP.

Lab Chip. 2012 Aug 21;12(16):2843-9. doi: 10.1039/c2lc40317j. Epub 2012 May 31.

PMID:
22647973

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