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Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model.

Contreras A, Beems MV, Tatar AJ, Sen S, Srinand P, Suresh M, Luther TK, Cho CS.

J Immunother Cancer. 2018 May 29;6(1):41. doi: 10.1186/s40425-018-0358-2.


Inverse association of rab31 and mucin-1 (CA15-3) antigen levels in estrogen receptor-positive (ER+) breast cancer tissues with clinicopathological parameters and patients' prognosis.

Kotzsch M, Kirchner T, Soelch S, Schäfer S, Friedrich K, Baretton G, Magdolen V, Luther T.

Am J Cancer Res. 2017 Sep 1;7(9):1959-1970. eCollection 2017.


Traditional uses of medicinal plants to prevent and treat diabetes; an updated review of ethnobotanical studies in Iran.

Asadi-Samani M, Moradi MT, Mahmoodnia L, Alaei S, Asadi-Samani F, Luther T.

J Nephropathol. 2017 Jul;6(3):118-125. doi: 10.15171/jnp.2017.20. Epub 2017 Jan 15. Review.


A Review of Medicinal Plants for the Treatment of Earache and Tinnitus in Iran.

Mahmoudian-Sani MR, Hashemzadeh-Chaleshtori M, Asadi-Samani M, Luther T.

Int Tinnitus J. 2017 Jun 1;21(1):44-49. doi: 10.5935/0946-5448.20170009. Review.


RAD51 Mediates Resistance of Cancer Stem Cells to PARP Inhibition in Triple-Negative Breast Cancer.

Liu Y, Burness ML, Martin-Trevino R, Guy J, Bai S, Harouaka R, Brooks MD, Shang L, Fox A, Luther TK, Davis A, Baker TL, Colacino J, Clouthier SG, Shao ZM, Wicha MS, Liu S.

Clin Cancer Res. 2017 Jan 15;23(2):514-522. doi: 10.1158/1078-0432.CCR-15-1348. Epub 2016 Dec 29.


Physiological aspects of Toll-like receptor 4 activation in sepsis-induced acute kidney injury.

Anderberg SB, Luther T, Frithiof R.

Acta Physiol (Oxf). 2017 Mar;219(3):573-588. doi: 10.1111/apha.12798. Epub 2016 Oct 8. Review.


Elimination of epithelial-like and mesenchymal-like breast cancer stem cells to inhibit metastasis following nanoparticle-mediated photothermal therapy.

Paholak HJ, Stevers NO, Chen H, Burnett JP, He M, Korkaya H, McDermott SP, Deol Y, Clouthier SG, Luther T, Li Q, Wicha MS, Sun D.

Biomaterials. 2016 Oct;104:145-57. doi: 10.1016/j.biomaterials.2016.06.045. Epub 2016 Jun 23.


Role of microRNA221 in regulating normal mammary epithelial hierarchy and breast cancer stem-like cells.

Ke J, Zhao Z, Hong SH, Bai S, He Z, Malik F, Xu J, Zhou L, Chen W, Martin-Trevino R, Wu X, Lan P, Yi Y, Ginestier C, Ibarra I, Shang L, McDermott S, Luther T, Clouthier SG, Wicha MS, Liu S.

Oncotarget. 2015 Feb 28;6(6):3709-21.


Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity.

D'Angelo RC, Ouzounova M, Davis A, Choi D, Tchuenkam SM, Kim G, Luther T, Quraishi AA, Senbabaoglu Y, Conley SJ, Clouthier SG, Hassan KA, Wicha MS, Korkaya H.

Mol Cancer Ther. 2015 Mar;14(3):779-787. doi: 10.1158/1535-7163.MCT-14-0228. Epub 2015 Feb 11.


MicroRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development.

Deng L, Shang L, Bai S, Chen J, He X, Martin-Trevino R, Chen S, Li XY, Meng X, Yu B, Wang X, Liu Y, McDermott SP, Ariazi AE, Ginestier C, Ibarra I, Ke J, Luther T, Clouthier SG, Xu L, Shan G, Song E, Yao H, Hannon GJ, Weiss SJ, Wicha MS, Liu S.

Cancer Res. 2014 Nov 15;74(22):6648-60. doi: 10.1158/0008-5472.CAN-13-3710. Epub 2014 Sep 12.


Platelet tissue factor: to be or not to be.

Mackman N, Luther T.

Thromb Res. 2013 Jul;132(1):3-5. doi: 10.1016/j.thromres.2013.05.009. Epub 2013 May 31. No abstract available.


Overexpression of the urokinase receptor splice variant uPAR-del4/5 in breast cancer cells affects cell adhesion and invasion in a dose-dependent manner and modulates transcription of tumor-associated genes.

Grismayer B, Sato S, Kopitz C, Ries C, Soelch S, Schmitt M, Baretton G, Krüger A, Luther T, Kotzsch M, Magdolen V.

Biol Chem. 2012 Dec;393(12):1449-55.


HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab.

Ithimakin S, Day KC, Malik F, Zen Q, Dawsey SJ, Bersano-Begey TF, Quraishi AA, Ignatoski KW, Daignault S, Davis A, Hall CL, Palanisamy N, Heath AN, Tawakkol N, Luther TK, Clouthier SG, Chadwick WA, Day ML, Kleer CG, Thomas DG, Hayes DF, Korkaya H, Wicha MS.

Cancer Res. 2013 Mar 1;73(5):1635-46. doi: 10.1158/0008-5472.CAN-12-3349. Epub 2013 Feb 26.


Rab31 expression levels modulate tumor-relevant characteristics of breast cancer cells.

Grismayer B, Sölch S, Seubert B, Kirchner T, Schäfer S, Baretton G, Schmitt M, Luther T, Krüger A, Kotzsch M, Magdolen V.

Mol Cancer. 2012 Aug 24;11:62. doi: 10.1186/1476-4598-11-62.


Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population.

Korkaya H, Kim GI, Davis A, Malik F, Henry NL, Ithimakin S, Quraishi AA, Tawakkol N, D'Angelo R, Paulson AK, Chung S, Luther T, Paholak HJ, Liu S, Hassan KA, Zen Q, Clouthier SG, Wicha MS.

Mol Cell. 2012 Aug 24;47(4):570-84. doi: 10.1016/j.molcel.2012.06.014. Epub 2012 Jul 19.


Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients.

Kotzsch M, Magdolen V, Greither T, Kappler M, Bache M, Lautenschläger C, Füssel S, Eckert AW, Luther T, Baretton G, Würl P, Taubert H.

BMC Cancer. 2011 Jun 25;11:273. doi: 10.1186/1471-2407-11-273.


Gene expression analysis of HUVEC in response to TF-binding.

Grosser M, Magdolen V, Baretton G, Luther T, Albrecht S.

Thromb Res. 2011 Mar;127(3):259-63. doi: 10.1016/j.thromres.2010.11.024. Epub 2010 Dec 24.


Prognostic relevance of tumour cell-associated uPAR expression in invasive ductal breast carcinoma.

Kotzsch M, Bernt K, Friedrich K, Luther E, Albrecht S, Gatzweiler A, Magdolen V, Baretton G, Zietz C, Luther T.

Histopathology. 2010 Sep;57(3):461-71. doi: 10.1111/j.1365-2559.2010.03644.x.


Overexpression of the urokinase receptor mRNA splice variant uPAR-del4/5 affects tumor-associated processes of breast cancer cells in vitro and in vivo.

Sato S, Kopitz C, Grismayer B, Beaufort N, Reuning U, Schmitt M, Luther T, Kotzsch M, Krüger A, Magdolen V.

Breast Cancer Res Treat. 2011 Jun;127(3):649-57. doi: 10.1007/s10549-010-1042-5. Epub 2010 Jul 16.


Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice.

Pawlinski R, Wang JG, Owens AP 3rd, Williams J, Antoniak S, Tencati M, Luther T, Rowley JW, Low EN, Weyrich AS, Mackman N.

Blood. 2010 Aug 5;116(5):806-14. doi: 10.1182/blood-2009-12-259267. Epub 2010 Apr 21.


Methods for analyzing saliva proteins for systemic disease detection.

Luther T, Carrion CF, Cobb N, Le G, Edwards C, Schwartz S, Streckfus C.

Gen Dent. 2010 Mar-Apr;58(2):110-3.


Statins potently reduce the cytokine-mediated IL-6 release in SMC/MNC cocultures.

Loppnow H, Zhang L, Buerke M, Lautenschläger M, Chen L, Frister A, Schlitt A, Luther T, Song N, Hofmann B, Rose-John S, Silber RE, Müller-Werdan U, Werdan K.

J Cell Mol Med. 2011 Apr;15(4):994-1004. doi: 10.1111/j.1582-4934.2010.01036.x.


Serum antibodies against human albumin in critically ill and healthy dogs.

Martin LG, Luther TY, Alperin DC, Gay JM, Hines SA.

J Am Vet Med Assoc. 2008 Apr 1;232(7):1004-9. doi: 10.2460/javma.232.7.1004.


Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy.

Pawlinski R, Tencati M, Hampton CR, Shishido T, Bullard TA, Casey LM, Andrade-Gordon P, Kotzsch M, Spring D, Luther T, Abe J, Pohlman TH, Verrier ED, Blaxall BC, Mackman N.

Circulation. 2007 Nov 13;116(20):2298-306. Epub 2007 Oct 29.


Urokinase receptor splice variant uPAR-del4/5-associated gene expression in breast cancer: identification of rab31 as an independent prognostic factor.

Kotzsch M, Sieuwerts AM, Grosser M, Meye A, Fuessel S, Meijer-van Gelder ME, Smid M, Schmitt M, Baretton G, Luther T, Magdolen V, Foekens JA.

Breast Cancer Res Treat. 2008 Sep;111(2):229-40. Epub 2007 Oct 20.


Adverse reactions suggestive of type III hypersensitivity in six healthy dogs given human albumin.

Francis AH, Martin LG, Haldorson GJ, Lahmers KK, Luther TY, Alperin DC, Hines SA.

J Am Vet Med Assoc. 2007 Mar 15;230(6):873-9.


Quantitative reverse transcription-PCR assay for detection of mRNA encoding full-length human tissue kallikrein 7: prognostic relevance of KLK7 mRNA expression in breast cancer.

Holzscheiter L, Biermann JC, Kotzsch M, Prezas P, Farthmann J, Baretton G, Luther T, Tjan-Heijnen VC, Talieri M, Schmitt M, Sweep FC, Span PN, Magdolen V.

Clin Chem. 2006 Jun;52(6):1070-9. Epub 2006 Apr 20.


Prognostic relevance of uPAR-del4/5 and TIMP-3 mRNA expression levels in breast cancer.

Kotzsch M, Farthmann J, Meye A, Fuessel S, Baretton G, Tjan-Heijnen VC, Schmitt M, Luther T, Sweep FC, Magdolen V, Span PN.

Eur J Cancer. 2005 Nov;41(17):2760-8. Epub 2005 Oct 26.


Tissue factor as a link between wounding and tissue repair.

Chen J, Kasper M, Heck T, Nakagawa K, Humpert PM, Bai L, Wu G, Zhang Y, Luther T, Andrassy M, Schiekofer S, Hamann A, Morcos M, Chen B, Stern DM, Nawroth PP, Bierhaus A.

Diabetes. 2005 Jul;54(7):2143-54.


Clinical course of sarcoidosis in dependence on HLA-DRB1 allele frequencies, inflammatory markers, and the presence of M. tuberculosis DNA fragments.

Grosser M, Luther T, Fuessel M, Bickhardt J, Magdolen V, Baretton G.

Sarcoidosis Vasc Diffuse Lung Dis. 2005 Mar;22(1):66-74.


Cathepsin B, plasminogenactivator-inhibitor (PAI-1) and plasminogenactivator-receptor (uPAR) are prognostic factors for patients with non-small cell lung cancer.

Werle B, Kotzsch M, Lah TT, Kos J, Gabrijelcic-Geiger D, Spiess E, Schirren J, Ebert W, Fiehn W, Luther T, Magdolen V, Schmitt M, Harbeck N.

Anticancer Res. 2004 Nov-Dec;24(6):4147-61.


Perfluorocarbon attenuates response of concanavalin A-stimulated mononuclear blood cells without altering ligand-receptor interaction.

Haufe D, Luther T, Kotzsch M, Knels L, Koch T.

Am J Physiol Lung Cell Mol Physiol. 2004 Jul;287(1):L210-6. Epub 2004 Mar 5.


Validation of a novel tissue factor assay in experimental human endotoxemia.

Marsik C, Quehenberger P, Mackman N, Osterud B, Luther T, Jilma B.

Thromb Res. 2003;111(4-5):311-5.


Proteolytic regulation of the urokinase receptor/CD87 on monocytic cells by neutrophil elastase and cathepsin G.

Beaufort N, Leduc D, Rousselle JC, Magdolen V, Luther T, Namane A, Chignard M, Pidard D.

J Immunol. 2004 Jan 1;172(1):540-9.


Effects of enalapril on disseminated intravascular thrombin formation during systemic inflammation.

Marsik C, Graninger M, Mackman N, Osterud B, Luther T, Jilma B.

Cardiovasc Res. 2003 Oct 15;60(1):131-5.


[Papillary swelling and macular edema].

Luther TT, Roters S, Diestelhorst M.

Ophthalmologe. 2003 Jul;100(7):558-60. Epub 2003 Jun 26. German. No abstract available.


Identification of a novel urokinase receptor splice variant and its prognostic relevance in breast cancer.

Luther T, Kotzsch M, Meye A, Langerholc T, Füssel S, Olbricht N, Albrecht S, Ockert D, Muehlenweg B, Friedrich K, Grosser M, Schmitt M, Baretton G, Magdolen V.

Thromb Haemost. 2003 Apr;89(4):705-17.


Intravascular tissue factor pathway--a model for rapid initiation of coagulation within the blood vessel.

Engelmann B, Luther T, Müller I.

Thromb Haemost. 2003 Jan;89(1):3-8. Review.


Soluble tissue actor interferes with angiostatin-mediated inhibition of endothelial cell proliferation by lysine-specific interaction with plasminogen kringle domains.

Albrecht S, Magdolen V, Herzog U, Miles L, Kirschenhofer A, Baretton G, Luther T.

Thromb Haemost. 2002 Dec;88(6):1054-9.


Intravascular tissue factor initiates coagulation via circulating microvesicles and platelets.

Müller I, Klocke A, Alex M, Kotzsch M, Luther T, Morgenstern E, Zieseniss S, Zahler S, Preissner K, Engelmann B.

FASEB J. 2003 Mar;17(3):476-8. Epub 2003 Jan 2.


Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.

Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15333-8. Epub 2002 Nov 8.


Autologous transplantation of genetically modified iris pigment epithelial cells: a promising concept for the treatment of age-related macular degeneration and other disorders of the eye.

Semkova I, Kreppel F, Welsandt G, Luther T, Kozlowski J, Janicki H, Kochanek S, Schraermeyer U.

Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13090-5. Epub 2002 Sep 18.


Vitreous treatment of cultured human RPE cells results in differential expression of 10 new genes.

Kociok N, Hueber A, Esser P, Schraermeyer U, Thumann G, Luther TT, Jordan J, Welsandt G, Kirchhof B.

Invest Ophthalmol Vis Sci. 2002 Jul;43(7):2474-80.


Long-term transgene expression in the RPE after gene transfer with a high-capacity adenoviral vector.

Kreppel F, Luther TT, Semkova I, Schraermeyer U, Kochanek S.

Invest Ophthalmol Vis Sci. 2002 Jun;43(6):1965-70.


Cortical neurons of Creutzfeldt-Jakob disease patients express the urokinase-type plasminogen activator receptor.

Deininger MH, Trautmann K, Magdolen V, Luther T, Schluesener HJ, Meyermann R.

Neurosci Lett. 2002 May 10;324(1):80-2.


Subretinally transplanted embryonic stem cells rescue photoreceptor cells from degeneration in the RCS rats.

Schraermeyer U, Thumann G, Luther T, Kociok N, Armhold S, Kruttwig K, Andressen C, Addicks K, Bartz-Schmidt KU.

Cell Transplant. 2001;10(8):673-80.


Tissue factor-dependent pathway is not involved in exercise-induced formation of thrombin and fibrin.

Weiss C, Bierhaus A, Kinscherf R, Hack V, Luther T, Nawroth PP, Bärtsch P.

J Appl Physiol (1985). 2002 Jan;92(1):211-8.


Tissue factor in the heart. Multiple roles in hemostasis, thrombosis, and inflammation.

Luther T, Mackman N.

Trends Cardiovasc Med. 2001 Nov;11(8):307-12. Review.


Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB.

Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Klöting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, Häring HU, Schleicher E, Nawroth PP.

Diabetes. 2001 Dec;50(12):2792-808.

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