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Items: 1 to 50 of 169

1.

A novel iterative mixed model to remap three complex orthopedic traits in dogs.

Huang M, Hayward JJ, Corey E, Garrison SJ, Wagner GR, Krotscheck U, Hayashi K, Schweitzer PA, Lust G, Boyko AR, Todhunter RJ.

PLoS One. 2017 Jun 14;12(6):e0176932. doi: 10.1371/journal.pone.0176932. eCollection 2017.

2.

The S-measurement in the diagnosis of canine hip dysplasia.

Ogden DM, Scrivani PV, Dykes N, Lust G, Friedenberg SG, Todhunter RJ.

Vet Surg. 2012 Jan;41(1):78-85. doi: 10.1111/j.1532-950X.2011.00874.x. Epub 2011 Sep 14.

PMID:
22091931
3.

Evaluation of a fibrillin 2 gene haplotype associated with hip dysplasia and incipient osteoarthritis in dogs.

Friedenberg SG, Zhu L, Zhang Z, Foels Wv, Schweitzer PA, Wang W, Fisher PJ, Dykes NL, Corey E, Vernier-Singer M, Jung SW, Sheng X, Hunter LS, McDonough SP, Lust G, Bliss SP, Krotscheck U, Gunn TM, Todhunter RJ.

Am J Vet Res. 2011 Apr;72(4):530-40. doi: 10.2460/ajvr.72.4.530.

PMID:
21453155
4.

Canine hip dysplasia is predictable by genotyping.

Guo G, Zhou Z, Wang Y, Zhao K, Zhu L, Lust G, Hunter L, Friedenberg S, Li J, Zhang Y, Harris S, Jones P, Sandler J, Krotscheck U, Todhunter R, Zhang Z.

Osteoarthritis Cartilage. 2011 Apr;19(4):420-9. doi: 10.1016/j.joca.2010.12.011. Epub 2011 Jan 5.

5.

Differential genetic regulation of canine hip dysplasia and osteoarthritis.

Zhou Z, Sheng X, Zhang Z, Zhao K, Zhu L, Guo G, Friedenberg SG, Hunter LS, Vandenberg-Foels WS, Hornbuckle WE, Krotscheck U, Corey E, Moise NS, Dykes NL, Li J, Xu S, Du L, Wang Y, Sandler J, Acland GM, Lust G, Todhunter RJ.

PLoS One. 2010 Oct 11;5(10):e13219. doi: 10.1371/journal.pone.0013219.

6.

Retrospective analysis for genetic improvement of hip joints of cohort labrador retrievers in the United States: 1970-2007.

Hou Y, Wang Y, Lust G, Zhu L, Zhang Z, Todhunter RJ.

PLoS One. 2010 Feb 24;5(2):e9410. doi: 10.1371/journal.pone.0009410.

7.

Canine hip dysplasia: another perspective.

Lust G.

Vet J. 2010 Mar;183(3):247-8. doi: 10.1016/j.tvjl.2009.12.017. Epub 2010 Jan 22. No abstract available.

PMID:
20097111
8.

Evaluation of quantitative trait loci for hip dysplasia in Labrador Retrievers.

Phavaphutanon J, Mateescu RG, Tsai KL, Schweitzer PA, Corey EE, Vernier-Singer MA, Williams AJ, Dykes NL, Murphy KE, Lust G, Todhunter RJ.

Am J Vet Res. 2009 Sep;70(9):1094-101. doi: 10.2460/ajvr.70.9.1094.

PMID:
19719424
9.

Estimation of heritabilities, genetic correlations, and breeding values of four traits that collectively define hip dysplasia in dogs.

Zhang Z, Zhu L, Sandler J, Friedenberg SS, Egelhoff J, Williams AJ, Dykes NL, Hornbuckle W, Krotscheck U, Moise NS, Lust G, Todhunter RJ.

Am J Vet Res. 2009 Apr;70(4):483-92. doi: 10.2460/ajvr.70.4.483.

PMID:
19335104
10.

The long (and winding) road to gene discovery for canine hip dysplasia.

Zhu L, Zhang Z, Friedenberg S, Jung SW, Phavaphutanon J, Vernier-Singer M, Corey E, Mateescu R, Dykes N, Sandler J, Acland G, Lust G, Todhunter R.

Vet J. 2009 Aug;181(2):97-110. doi: 10.1016/j.tvjl.2009.02.008. Epub 2009 Mar 17. Review.

11.

Identification of quantitative trait loci for osteoarthritis of hip joints in dogs.

Mateescu RG, Burton-Wurster NI, Tsai K, Phavaphutanon J, Zhang Z, Murphy KE, Lust G, Todhunter RJ.

Am J Vet Res. 2008 Oct;69(10):1294-300. doi: 10.2460/ajvr.69.10.1294.

PMID:
18828685
12.

Single nucleotide polymorphisms refine QTL intervals for hip joint laxity in dogs.

Zhu L, Zhang Z, Feng F, Schweitzer P, Phavaphutanon J, Vernier-Singer M, Corey E, Friedenberg S, Mateescu R, Williams A, Lust G, Acland G, Todhunter R.

Anim Genet. 2008 Apr;39(2):141-6. doi: 10.1111/j.1365-2052.2007.01691.x. Epub 2008 Feb 6.

PMID:
18261189
13.

Transmission of relaxin and estrogens to suckling canine pups via milk and possible association with hip joint laxity.

Steinetz BG, Williams AJ, Lust G, Schwabe C, B├╝llesbach EE, Goldsmith LT.

Am J Vet Res. 2008 Jan;69(1):59-67. doi: 10.2460/ajvr.69.1.59.

PMID:
18167088
14.

A random model for mapping imprinted quantitative trait loci in a structured pedigree: an implication for mapping canine hip dysplasia.

Liu T, Todhunter RJ, Wu S, Hou W, Mateescu R, Zhang Z, Burton-Wurster NI, Acland GM, Lust G, Wu R.

Genomics. 2007 Aug;90(2):276-84. Epub 2007 May 24.

15.

Linkage and segregation analysis of black and brindle coat color in domestic dogs.

Kerns JA, Cargill EJ, Clark LA, Candille SI, Berryere TG, Olivier M, Lust G, Todhunter RJ, Schmutz SM, Murphy KE, Barsh GS.

Genetics. 2007 Jul;176(3):1679-89. Epub 2007 May 4.

16.

Morphological changes in articular cartilage due to static compression: polarized light microscopy study.

Alhadlaq HA, Xia Y, Hansen FM, Les CM, Lust G.

Connect Tissue Res. 2007;48(2):76-84.

PMID:
17453909
17.

Quantitative genetics of secondary hip joint osteoarthritis in a Labrador Retriever-Greyhound pedigree.

Hays L, Zhang Z, Mateescu RG, Lust G, Burton-Wurster NI, Todhunter RJ.

Am J Vet Res. 2007 Jan;68(1):35-41.

PMID:
17199416
18.

Modeling extent and distribution of zygotic disequilibrium: implications for a multigenerational canine pedigree.

Liu T, Todhunter RJ, Lu Q, Schoettinger L, Li H, Littell RC, Burton-Wurster N, Acland GM, Lust G, Wu R.

Genetics. 2006 Sep;174(1):439-53. Epub 2006 Jul 18.

19.

Assessment of bone mineral density of the femoral head in dogs with early osteoarthritis.

Chalmers HJ, Dykes NL, Lust G, Farese JP, Burton-Wurster NI, Williams AJ, Todhunter RJ.

Am J Vet Res. 2006 May;67(5):796-800.

PMID:
16649912
20.

Analysis of allele fidelity, polymorphic information content, and density of microsatellites in a genome-wide screening for hip dysplasia in a crossbreed pedigree.

Mateescu RG, Zhang Z, Tsai K, Phavaphutanon J, Burton-Wurster NI, Lust G, Quaas R, Murphy K, Acland GM, Todhunter RJ.

J Hered. 2005;96(7):847-53. Epub 2005 Oct 26.

PMID:
16251522
21.

Quantitative trait loci for hip dysplasia in a cross-breed canine pedigree.

Todhunter RJ, Mateescu R, Lust G, Burton-Wurster NI, Dykes NL, Bliss SP, Williams AJ, Vernier-Singer M, Corey E, Harjes C, Quaas RL, Zhang Z, Gilbert RO, Volkman D, Casella G, Wu R, Acland GM.

Mamm Genome. 2005 Sep;16(9):720-30. Epub 2005 Oct 20.

PMID:
16245029
22.

Genes in canine articular cartilage that respond to mechanical injury: gene expression studies with Affymetrix canine GeneChip.

Burton-Wurster N, Mateescu RG, Todhunter RJ, Clements KM, Sun Q, Scarpino V, Lust G.

J Hered. 2005;96(7):821-8. Epub 2005 Sep 8.

PMID:
16150951
23.

Increased MIG-6 mRNA transcripts in osteoarthritic cartilage.

Mateescu RG, Todhunter RJ, Lust G, Burton-Wurster N.

Biochem Biophys Res Commun. 2005 Jul 1;332(2):482-6.

PMID:
15910752
24.

Caspase-3/7 inhibition alters cell morphology in mitomycin-C treated chondrocytes.

Clements KM, Burton-Wurster N, Nuttall ME, Lust G.

J Cell Physiol. 2005 Oct;205(1):133-40.

PMID:
15828017
25.

The potential and limitations of cartilage-specific (V+C)(-) fibronectin and cartilage oligomeric matrix protein as osteoarthritis biomarkers in canine synovial fluid.

Steffey MA, Miura N, Todhunter RJ, Nykamp SG, Freeman KP, Scarpino V, Vernier-Singer MA, Erb HN, MacLeod JN, Lust G, Burton-Wurster N.

Osteoarthritis Cartilage. 2004 Oct;12(10):818-25.

26.

The spread of cell death from impact damaged cartilage: lack of evidence for the role of nitric oxide and caspases.

Clements KM, Burton-Wurster N, Lust G.

Osteoarthritis Cartilage. 2004 Jul;12(7):577-85.

27.

Evaluation of multiple radiographic predictors of cartilage lesions in the hip joints of eight-month-old dogs.

Todhunter RJ, Grohn YT, Bliss SP, Wilfand A, Williams AJ, Vernier-Singer M, Burton-Wurster NI, Dykes NL, Wu R, Casella G, Acland GM, Lust G.

Am J Vet Res. 2003 Dec;64(12):1472-8.

PMID:
14672422
28.

The extent and distribution of linkage disequilibrium in a multi-hierarchic outbred canine pedigree.

Lou XY, Todhunter RJ, Lin M, Lu Q, Liu T, Wang Z, Bliss SP, Casella G, Acland GM, Lust G, Wu R.

Mamm Genome. 2003 Aug;14(8):555-64.

PMID:
12925888
29.

Spontaneous and experimental osteoarthritis in dog: similarities and differences in proteoglycan levels.

Liu W, Burton-Wurster N, Glant TT, Tashman S, Sumner DR, Kamath RV, Lust G, Kimura JH, Cs-Szabo G.

J Orthop Res. 2003 Jul;21(4):730-7.

30.

Effect of dorsal hip loading, sedation, and general anesthesia on the dorsolateral subluxation score in dogs.

Todhunter RJ, Bertram JE, Smith S, Farese JP, Williams AJ, Manocchia A, Erb HN, Dykes NL, Burton-Wurster NI, Lust G.

Vet Surg. 2003 May-Jun;32(3):196-205.

PMID:
12784195
31.

Power of a Labrador Retriever-Greyhound pedigree for linkage analysis of hip dysplasia and osteoarthritis.

Todhunter RJ, Casella G, Bliss SP, Lust G, Williams AJ, Hamilton S, Dykes NL, Yeager AE, Gilbert RO, Burton-Wurster NI, Mellersh CC, Acland GM.

Am J Vet Res. 2003 Apr;64(4):418-24.

PMID:
12693530
32.

Exclusion of melanocortin-1 receptor (mc1r) and agouti as candidates for dominant black in dogs.

Kerns JA, Olivier M, Lust G, Barsh GS.

J Hered. 2003 Jan-Feb;94(1):75-9.

PMID:
12692166
33.

Genetic structure of susceptibility traits for hip dysplasia and microsatellite informativeness of an outcrossed canine pedigree.

Todhunter RJ, Bliss SP, Casella G, Wu R, Lust G, Burton-Wurster NI, Williams AJ, Gilbert RO, Acland GM.

J Hered. 2003 Jan-Feb;94(1):39-48.

PMID:
12692161
34.

TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage.

Burton-Wurster N, Liu W, Matthews GL, Lust G, Roughley PJ, Glant TT, Cs-Szab├│ G.

Osteoarthritis Cartilage. 2003 Mar;11(3):167-76.

35.

The cartilage-specific fibronectin isoform has a high affinity binding site for the small proteoglycan decorin.

Gendelman R, Burton-Wurster NI, MacLeod JN, Lust G.

J Biol Chem. 2003 Mar 28;278(13):11175-81. Epub 2002 Dec 12.

36.

Specific immunological detection of the (V+C)(-) fibronectin isoform.

Burton-Wurster N, Chen H, Gendelman R, Jackson ML, Gagliardo LF, Gu DN, Zelko RR, Lust G, MacLeod JN.

Matrix Biol. 2002 Aug;21(5):393-8.

PMID:
12225804
37.

Quantitative genetics of traits associated with hip dysplasia in a canine pedigree constructed by mating dysplastic Labrador Retrievers with unaffected Greyhounds.

Bliss S, Todhunter RJ, Quaas R, Casella G, Wu R, Lust G, Williams AJ, Hamilton S, Dykes NL, Yeager A, Gilbert RO, Burton-Wurster NI, Acland GM.

Am J Vet Res. 2002 Jul;63(7):1029-35.

PMID:
12118665
38.

Characteristics of topographical heterogeneity of articular cartilage over the joint surface of a humeral head.

Xia Y, Moody JB, Alhadlaq H, Burton-Wurster N, Lust G.

Osteoarthritis Cartilage. 2002 May;10(5):370-80.

39.

Effects of diet restriction on life span and age-related changes in dogs.

Kealy RD, Lawler DF, Ballam JM, Mantz SL, Biery DN, Greeley EH, Lust G, Segre M, Smith GK, Stowe HD.

J Am Vet Med Assoc. 2002 May 1;220(9):1315-20.

PMID:
11991408
40.

Insulin-like growth factor-I enhances cell-based repair of articular cartilage.

Fortier LA, Mohammed HO, Lust G, Nixon AJ.

J Bone Joint Surg Br. 2002 Mar;84(2):276-88.

PMID:
11922373
42.

Intercellular signaling as a cause of cell death in cyclically impacted cartilage explants.

Levin A, Burton-Wurster N, Chen CT, Lust G.

Osteoarthritis Cartilage. 2001 Nov;9(8):702-11.

43.

Repeatability of dorsolateral subluxation scores in dogs and correlation with macroscopic appearance of hip osteoarthritis.

Lust G, Todhunter RJ, Erb HN, Dykes NL, Williams AJ, Burton-Wurster NI, Farese JP.

Am J Vet Res. 2001 Nov;62(11):1711-5.

PMID:
11703012
44.

Comparison of three radiographic methods for diagnosis of hip dysplasia in eight-month-old dogs.

Lust G, Todhunter RJ, Erb HN, Dykes NL, Williams AJ, Burton-Wurster NI, Farese JP.

J Am Vet Med Assoc. 2001 Nov 1;219(9):1242-6.

PMID:
11697367
45.

Chondrocyte necrosis and apoptosis in impact damaged articular cartilage.

Chen CT, Burton-Wurster N, Borden C, Hueffer K, Bloom SE, Lust G.

J Orthop Res. 2001 Jul;19(4):703-11.

46.

Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage.

Xia Y, Moody JB, Burton-Wurster N, Lust G.

Osteoarthritis Cartilage. 2001 Jul;9(5):393-406.

47.

Evaluation of the effect of limited food consumption on radiographic evidence of osteoarthritis in dogs.

Kealy RD, Lawler DF, Ballam JM, Lust G, Biery DN, Smith GK, Mantz SL.

J Am Vet Med Assoc. 2000 Dec 1;217(11):1678-80.

PMID:
11110459
48.

The effects of methylprednisolone on normal and monocyte-conditioned medium-treated articular cartilage from dogs and horses.

Murphy DJ, Todhunter RJ, Fubini SL, Vernier-Singer M, Straubinger RK, Lust G.

Vet Surg. 2000 Nov-Dec;29(6):546-57.

PMID:
11098788
49.

Compositional and metabolic changes in damaged cartilage are peak-stress, stress-rate, and loading-duration dependent.

Chen CT, Burton-Wurster N, Lust G, Bank RA, Tekoppele JM.

J Orthop Res. 1999 Nov;17(6):870-9.

PMID:
10632454
50.

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