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Items: 1 to 50 of 126

1.

Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke.

Werner Y, Mass E, Ashok Kumar P, Ulas T, Händler K, Horne A, Klee K, Lupp A, Schütz D, Saaber F, Redecker C, Schultze JL, Geissmann F, Stumm R.

Nat Neurosci. 2020 Mar;23(3):351-362. doi: 10.1038/s41593-020-0585-y. Epub 2020 Feb 10.

PMID:
32042176
2.

Comprehensive assessment of tissue and serum parameters of bone metabolism in a series of orthopaedic patients.

Gunsser J, Hermann R, Roth A, Lupp A.

PLoS One. 2019 Dec 27;14(12):e0227133. doi: 10.1371/journal.pone.0227133. eCollection 2019.

3.

Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody.

Herzig M, Dasgupta P, Kaemmerer D, Sänger J, Evert K, Schulz S, Lupp A.

Int J Mol Sci. 2019 Oct 23;20(21). pii: E5261. doi: 10.3390/ijms20215261.

4.

Somatostatin and chemokine CXCR4 receptor expression in pancreatic adenocarcinoma relative to pancreatic neuroendocrine tumours.

Kajtazi Y, Kaemmerer D, Sänger J, Schulz S, Lupp A.

J Cancer Res Clin Oncol. 2019 Oct;145(10):2481-2493. doi: 10.1007/s00432-019-03011-0. Epub 2019 Aug 26.

PMID:
31451931
5.

Different somatostatin and CXCR4 chemokine receptor expression in gastroenteropancreatic neuroendocrine neoplasms depending on their origin.

Mai R, Kaemmerer D, Träger T, Neubauer E, Sänger J, Baum RP, Schulz S, Lupp A.

Sci Rep. 2019 Mar 13;9(1):4339. doi: 10.1038/s41598-019-39607-2.

6.

Acid Sphingomyelinase Inhibition Stabilizes Hepatic Ceramide Content and Improves Hepatic Biotransformation Capacity in a Murine Model of Polymicrobial Sepsis.

Chung HY, Witt CJ, Hurtado-Oliveros J, Wickel J, Gräler MH, Lupp A, Claus RA.

Int J Mol Sci. 2018 Oct 15;19(10). pii: E3163. doi: 10.3390/ijms19103163.

7.

International Union of Basic and Clinical Pharmacology. CV. Somatostatin Receptors: Structure, Function, Ligands, and New Nomenclature.

Günther T, Tulipano G, Dournaud P, Bousquet C, Csaba Z, Kreienkamp HJ, Lupp A, Korbonits M, Castaño JP, Wester HJ, Culler M, Melmed S, Schulz S.

Pharmacol Rev. 2018 Oct;70(4):763-835. doi: 10.1124/pr.117.015388. Review.

8.

Somatostatin and CXCR4 expression patterns in adenocarcinoma and squamous cell carcinoma of the lung relative to small cell lung cancer.

Stumpf C, Kaemmerer D, Neubauer E, Sänger J, Schulz S, Lupp A.

J Cancer Res Clin Oncol. 2018 Oct;144(10):1921-1932. doi: 10.1007/s00432-018-2722-5. Epub 2018 Aug 3.

PMID:
30076481
9.

Corrigendum: Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.

Gröger M, Rennert K, Giszas B, Weiß E, Dinger J, Funke H, Kiehntopf M, Peters FT, Lupp A, Bauer M, Claus RA, Huber O, Mosig AS.

Sci Rep. 2018 May 14;8:46988. doi: 10.1038/srep46988.

10.

Protective Effect of Casperome®, an Orally Bioavailable Frankincense Extract, on Lipopolysaccharide- Induced Systemic Inflammation in Mice.

Loeser K, Seemann S, König S, Lenhardt I, Abdel-Tawab M, Koeberle A, Werz O, Lupp A.

Front Pharmacol. 2018 Apr 20;9:387. doi: 10.3389/fphar.2018.00387. eCollection 2018.

11.

Differential somatostatin, CXCR4 chemokine and endothelin A receptor expression in WHO grade I-IV astrocytic brain tumors.

Lange F, Kaemmerer D, Behnke-Mursch J, Brück W, Schulz S, Lupp A.

J Cancer Res Clin Oncol. 2018 Jul;144(7):1227-1237. doi: 10.1007/s00432-018-2645-1. Epub 2018 Apr 25.

PMID:
29696364
12.

Morphologically 'invisible' proinsulin - secreting adenoma detected by Ga-68 Exendin-4 (GLP-1 Receptor) positron emission tomography/CT.

Werner C, Lupp A, Drescher R, Freesmeyer M, Mireskandari M, Stoykow C, Bauschke A, Müller UA.

J Med Imaging Radiat Oncol. 2018 Jun;62(3):370-374. doi: 10.1111/1754-9485.12704. Epub 2018 Feb 5.

PMID:
29399966
13.

Somatostatin and CXCR4 chemokine receptor expression in hepatocellular and cholangiocellular carcinomas: tumor capillaries as promising targets.

Kaemmerer D, Schindler R, Mußbach F, Dahmen U, Altendorf-Hofmann A, Dirsch O, Sänger J, Schulz S, Lupp A.

BMC Cancer. 2017 Dec 28;17(1):896. doi: 10.1186/s12885-017-3911-3.

14.

Proteasome inhibitor bortezomib enhances the effect of standard chemotherapy in small cell lung cancer.

Taromi S, Lewens F, Arsenic R, Sedding D, Sänger J, Kunze A, Möbs M, Benecke J, Freitag H, Christen F, Kaemmerer D, Lupp A, Heilmann M, Lammert H, Schneider CP, Richter K, Hummel M, Siegmund B, Burger M, Briest F, Grabowski P.

Oncotarget. 2017 Sep 23;8(57):97061-97078. doi: 10.18632/oncotarget.21221. eCollection 2017 Nov 14.

15.

Evaluation of somatostatin, CXCR4 chemokine and endothelin A receptor expression in a large set of paragangliomas.

Kaemmerer D, Sänger J, Arsenic R, D'Haese JG, Neumann J, Schmitt-Graeff A, Wirtz RM, Schulz S, Lupp A.

Oncotarget. 2017 Sep 23;8(52):89958-89969. doi: 10.18632/oncotarget.21194. eCollection 2017 Oct 27.

16.

Ischemia-Reperfusion Injury in Aged Livers-The Energy Metabolism, Inflammatory Response, and Autophagy.

Kan C, Ungelenk L, Lupp A, Dirsch O, Dahmen U.

Transplantation. 2018 Mar;102(3):368-377. doi: 10.1097/TP.0000000000001999. Review.

PMID:
29135887
17.

Acid Sphingomyelinase Inhibition Prevents Development of Sepsis Sequelae in the Murine Liver.

Chung HY, Witt CJ, Jbeily N, Hurtado-Oliveros J, Giszas B, Lupp A, Gräler MH, Bruns T, Stallmach A, Gonnert FA, Claus RA.

Sci Rep. 2017 Sep 27;7(1):12348. doi: 10.1038/s41598-017-11837-2.

18.

Comprehensive comparison of three different animal models for systemic inflammation.

Seemann S, Zohles F, Lupp A.

J Biomed Sci. 2017 Aug 24;24(1):60. doi: 10.1186/s12929-017-0370-8.

19.

Evaluation of HepaRG cells for the assessment of indirect drug-induced hepatotoxicity using INH as a model substance.

Mann A, Pelz T, Rennert K, Mosig A, Decker M, Lupp A.

Hum Cell. 2017 Oct;30(4):267-278. doi: 10.1007/s13577-017-0175-9. Epub 2017 May 19.

PMID:
28527127
20.

Adjustment of Dysregulated Ceramide Metabolism in a Murine Model of Sepsis-Induced Cardiac Dysfunction.

Chung HY, Kollmey AS, Schrepper A, Kohl M, Bläss MF, Stehr SN, Lupp A, Gräler MH, Claus RA.

Int J Mol Sci. 2017 Apr 15;18(4). pii: E839. doi: 10.3390/ijms18040839.

21.

Oral Chemical Burns Reported to the Poisons Information Centre in Erfurt, Germany, from 1997 to 2014.

Nehrlich J, Klöcking HP, Hentschel H, Lupp A.

J Burn Care Res. 2017 Nov/Dec;38(6):e913-e922. doi: 10.1097/BCR.0000000000000518.

PMID:
28319530
22.

Erratum to: Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin.

Stollberg S, Kaemmerer D, Neubauer E, Schulz S, Simonitsch-Klupp I, Kiesewetter B, Raderer M, Lupp A.

J Cancer Res Clin Oncol. 2017 Jan;143(1):187. doi: 10.1007/s00432-016-2312-3. No abstract available.

PMID:
27909810
24.

Differential somatostatin and CXCR4 chemokine receptor expression in MALT-type lymphoma of gastric and extragastric origin.

Stollberg S, Kämmerer D, Neubauer E, Schulz S, Simonitsch-Klupp I, Kiesewetter B, Raderer M, Lupp A.

J Cancer Res Clin Oncol. 2016 Nov;142(11):2239-47. doi: 10.1007/s00432-016-2220-6. Epub 2016 Aug 20. Erratum in: J Cancer Res Clin Oncol. 2016 Dec 1;:.

PMID:
27544389
25.

Generation of Multicellular Breast Cancer Tumor Spheroids: Comparison of Different Protocols.

Froehlich K, Haeger JD, Heger J, Pastuschek J, Photini SM, Yan Y, Lupp A, Pfarrer C, Mrowka R, Schleußner E, Markert UR, Schmidt A.

J Mammary Gland Biol Neoplasia. 2016 Dec;21(3-4):89-98. Epub 2016 Aug 12. Review.

PMID:
27518775
26.

Comparative evaluation of three proliferation markers, Ki-67, TOP2A, and RacGAP1, in bronchopulmonary neuroendocrine neoplasms: Issues and prospects.

Neubauer E, Wirtz RM, Kaemmerer D, Athelogou M, Schmidt L, Sänger J, Lupp A.

Oncotarget. 2016 Jul 5;7(27):41959-41973. doi: 10.18632/oncotarget.9747.

27.

Monocyte-induced recovery of inflammation-associated hepatocellular dysfunction in a biochip-based human liver model.

Gröger M, Rennert K, Giszas B, Weiß E, Dinger J, Funke H, Kiehntopf M, Peters FT, Lupp A, Bauer M, Claus RA, Huber O, Mosig AS.

Sci Rep. 2016 Feb 23;6:21868. doi: 10.1038/srep21868. Erratum in: Sci Rep. 2018 May 14;8:46988.

28.

Effects of Narrow-band IR-A and of Water-Filtered Infrared A on Fibroblasts.

Knels L, Valtink M, Piazena H, de la Vega Marin J, Gommel K, Lupp A, Roehlecke C, Mehner M, Funk RH.

Photochem Photobiol. 2016 May;92(3):475-87. doi: 10.1111/php.12579. Epub 2016 Mar 17.

PMID:
26876482
29.

Primary-like human hepatocytes genetically engineered to obtain proliferation competence display hepatic differentiation characteristics in monolayer and organotypical spheroid cultures.

Herzog N, Hansen M, Miethbauer S, Schmidtke KU, Anderer U, Lupp A, Sperling S, Seehofer D, Damm G, Scheibner K, Küpper JH.

Cell Biol Int. 2016 Mar;40(3):341-53. doi: 10.1002/cbin.10574. Epub 2016 Jan 18.

PMID:
26715207
30.

Localization of Radiolabeled Somatostatin Analogs in the Spleen.

Melis M, Kaemmerer D, de Swart J, Kulkarni HR, Lupp A, Sänger J, Groen HC, Konijnenberg MW, de Jong M, Baum RP.

Clin Nucl Med. 2016 Feb;41(2):e111-4. doi: 10.1097/RLU.0000000000001026.

PMID:
26462044
31.

Administration of a CXCL12 Analog in Endotoxemia Is Associated with Anti-Inflammatory, Anti-Oxidative and Cytoprotective Effects In Vivo.

Seemann S, Lupp A.

PLoS One. 2015 Sep 16;10(9):e0138389. doi: 10.1371/journal.pone.0138389. eCollection 2015.

32.

A microfluidically perfused three dimensional human liver model.

Rennert K, Steinborn S, Gröger M, Ungerböck B, Jank AM, Ehgartner J, Nietzsche S, Dinger J, Kiehntopf M, Funke H, Peters FT, Lupp A, Gärtner C, Mayr T, Bauer M, Huber O, Mosig AS.

Biomaterials. 2015 Dec;71:119-131. doi: 10.1016/j.biomaterials.2015.08.043. Epub 2015 Aug 25.

PMID:
26322723
33.

Inverse expression of somatostatin and CXCR4 chemokine receptors in gastroenteropancreatic neuroendocrine neoplasms of different malignancy.

Kaemmerer D, Träger T, Hoffmeister M, Sipos B, Hommann M, Sänger J, Schulz S, Lupp A.

Oncotarget. 2015 Sep 29;6(29):27566-79. doi: 10.18632/oncotarget.4491.

34.

Analysis of somatostatin receptor 2A immunohistochemistry, RT-qPCR, and in vivo PET/CT data in patients with pancreatic neuroendocrine neoplasm.

Kaemmerer D, Wirtz RM, Fischer EK, Hommann M, Sänger J, Prasad V, Specht E, Baum RP, Schulz S, Lupp A.

Pancreas. 2015 May;44(4):648-54. doi: 10.1097/MPA.0000000000000316.

PMID:
25872131
35.

Reassessment of endothelin receptor A expression in normal and neoplastic human tissues using the novel rabbit monoclonal antibody UMB-8.

Lupp A, Mann A, Heeb A, Kaemmerer D, Sänger J, Evert M, Evert K, Mawrin C, Schulz S.

Peptides. 2015 Apr;66:19-25. doi: 10.1016/j.peptides.2015.02.005. Epub 2015 Feb 20.

PMID:
25708416
36.

Differential expression and prognostic value of the chemokine receptor CXCR4 in bronchopulmonary neuroendocrine neoplasms.

Kaemmerer D, Reimann C, Specht E, Wirtz RM, Sayeg M, Baum RP, Schulz S, Lupp A.

Oncotarget. 2015 Feb 20;6(5):3346-58.

37.

Comparison of immunoreactive score, HER2/neu score and H score for the immunohistochemical evaluation of somatostatin receptors in bronchopulmonary neuroendocrine neoplasms.

Specht E, Kaemmerer D, Sänger J, Wirtz RM, Schulz S, Lupp A.

Histopathology. 2015 Sep;67(3):368-77. doi: 10.1111/his.12662. Epub 2015 Mar 23.

PMID:
25641082
38.

SSTR3 is a putative target for the medical treatment of gonadotroph adenomas of the pituitary.

Lee M, Lupp A, Mendoza N, Martin N, Beschorner R, Honegger J, Schlegel J, Shively T, Pulz E, Schulz S, Roncaroli F, Pellegata NS.

Endocr Relat Cancer. 2015 Feb;22(1):111-9. doi: 10.1530/ERC-14-0472. Epub 2014 Dec 16.

PMID:
25515731
39.

VPAC2 receptor expression in human normal and neoplastic tissues: evaluation of the novel MAB SP235.

Schulz S, Mann A, Novakhov B, Piggins HD, Lupp A.

Endocr Connect. 2015 Mar;4(1):18-26. doi: 10.1530/EC-14-0051. Epub 2014 Dec 11.

40.

Somatostatin receptors in bronchopulmonary neuroendocrine neoplasms: new diagnostic, prognostic, and therapeutic markers.

Kaemmerer D, Specht E, Sänger J, Wirtz RM, Sayeg M, Schulz S, Lupp A.

J Clin Endocrinol Metab. 2015 Mar;100(3):831-40. doi: 10.1210/jc.2014-2699. Epub 2014 Dec 12.

PMID:
25494861
41.

Somatostatin receptor immunohistochemistry in neuroendocrine tumors: comparison between manual and automated evaluation.

Kaemmerer D, Athelogou M, Lupp A, Lenhardt I, Schulz S, Luisa P, Hommann M, Prasad V, Binnig G, Baum RP.

Int J Clin Exp Pathol. 2014 Jul 15;7(8):4971-80. eCollection 2014.

42.

Design, synthesis and biological evaluation of D-ring opened galantamine analogs as multifunctional anti-Alzheimer agents.

Fang L, Fang X, Gou S, Lupp A, Lenhardt I, Sun Y, Huang Z, Chen Y, Zhang Y, Fleck C.

Eur J Med Chem. 2014 Apr 9;76:376-86. doi: 10.1016/j.ejmech.2014.02.035. Epub 2014 Feb 14.

PMID:
24594525
43.

Physical exercise induces specific adaptations resulting in reduced organ injury and mortality during severe polymicrobial sepsis.

Sossdorf M, Fischer J, Meyer S, Dahlke K, Wissuwa B, Seidel C, Schrepper A, Bockmeyer CL, Lupp A, Neugebauer S, Schmerler D, Rödel J, Claus RA, Otto GP.

Crit Care Med. 2013 Oct;41(10):e246-55. doi: 10.1097/CCM.0b013e31828a2ae3.

PMID:
23887230
44.

Reevaluation of sst₁ somatostatin receptor expression in human normal and neoplastic tissues using the novel rabbit monoclonal antibody UMB-7.

Lupp A, Nagel F, Schulz S.

Regul Pept. 2013 May 10;183:1-6. doi: 10.1016/j.regpep.2013.02.001. Epub 2013 Mar 4.

PMID:
23466804
45.

Correlation of monoclonal and polyclonal somatostatin receptor 5 antibodies in pancreatic neuroendocrine tumors.

Kaemmerer D, Lupp A, Peter L, Fischer E, Schulz S, Klöppel G, Hommann M.

Int J Clin Exp Pathol. 2013;6(1):49-54. Epub 2012 Nov 20.

46.

Liver dysfunction and phosphatidylinositol-3-kinase signalling in early sepsis: experimental studies in rodent models of peritonitis.

Recknagel P, Gonnert FA, Westermann M, Lambeck S, Lupp A, Rudiger A, Dyson A, Carré JE, Kortgen A, Krafft C, Popp J, Sponholz C, Fuhrmann V, Hilger I, Claus RA, Riedemann NC, Wetzker R, Singer M, Trauner M, Bauer M.

PLoS Med. 2012;9(11):e1001338. doi: 10.1371/journal.pmed.1001338. Epub 2012 Nov 13.

47.

Mechanisms and functional consequences of liver failure substantially differ between endotoxaemia and faecal peritonitis in rats.

Recknagel P, Gonnert FA, Halilbasic E, Gajda M, Jbeily N, Lupp A, Rubio I, Claus RA, Kortgen A, Trauner M, Singer M, Bauer M.

Liver Int. 2013 Feb;33(2):283-93. doi: 10.1111/liv.12012. Epub 2012 Nov 12.

PMID:
23146068
48.

CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney.

Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R.

PLoS One. 2012;7(8):e42814. doi: 10.1371/journal.pone.0042814. Epub 2012 Aug 6.

49.

Somatostatin analogs modulate AIP in somatotroph adenomas: the role of the ZAC1 pathway.

Chahal HS, Trivellin G, Leontiou CA, Alband N, Fowkes RC, Tahir A, Igreja SC, Chapple JP, Jordan S, Lupp A, Schulz S, Ansorge O, Karavitaki N, Carlsen E, Wass JA, Grossman AB, Korbonits M.

J Clin Endocrinol Metab. 2012 Aug;97(8):E1411-20. doi: 10.1210/jc.2012-1111. Epub 2012 Jun 1.

PMID:
22659247
50.

Tacrine-silibinin codrug shows neuro- and hepatoprotective effects in vitro and pro-cognitive and hepatoprotective effects in vivo.

Chen X, Zenger K, Lupp A, Kling B, Heilmann J, Fleck C, Kraus B, Decker M.

J Med Chem. 2012 Jun 14;55(11):5231-42. doi: 10.1021/jm300246n. Epub 2012 May 24.

PMID:
22624880

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