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Items: 20


Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis.

Foo CS, Lupien A, Kienle M, Vocat A, Benjak A, Sommer R, Lamprecht DA, Steyn AJC, Pethe K, Piton J, Altmann KH, Cole ST.

mBio. 2018 Oct 9;9(5). pii: e01276-18. doi: 10.1128/mBio.01276-18.


Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169).

Lupien A, Vocat A, Foo CS, Blattes E, Gillon JY, Makarov V, Cole ST.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e00840-18. doi: 10.1128/AAC.00840-18. Print 2018 Nov.


Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis.

Piton J, Vocat A, Lupien A, Foo CS, Riabova O, Makarov V, Cole ST.

Antimicrob Agents Chemother. 2018 Sep 24;62(10). pii: e00681-18. doi: 10.1128/AAC.00681-18. Print 2018 Oct.


Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae.

Benjak A, Avanzi C, Singh P, Loiseau C, Girma S, Busso P, Fontes ANB, Miyamoto Y, Namisato M, Bobosha K, Salgado CG, da Silva MB, Bouth RC, Frade MAC, Filho FB, Barreto JG, Nery JAC, Bührer-Sékula S, Lupien A, Al-Samie AR, Al-Qubati Y, Alkubati AS, Bretzel G, Vera-Cabrera L, Sakho F, Johnson CR, Kodio M, Fomba A, Sow SO, Gado M, Konaté O, Stefani MMA, Penna GO, Suffys PN, Sarno EN, Moraes MO, Rosa PS, Baptista IMFD, Spencer JS, Aseffa A, Matsuoka M, Kai M, Cole ST.

Nat Commun. 2018 Jan 24;9(1):352. doi: 10.1038/s41467-017-02576-z.


Rv3852 (H-NS) of Mycobacterium tuberculosis Is Not Involved in Nucleoid Compaction and Virulence Regulation.

Odermatt NT, Sala C, Benjak A, Kolly GS, Vocat A, Lupien A, Cole ST.

J Bacteriol. 2017 Jul 25;199(16). pii: e00129-17. doi: 10.1128/JB.00129-17. Print 2017 Aug 15.


The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis.

Singh V, Donini S, Pacitto A, Sala C, Hartkoorn RC, Dhar N, Keri G, Ascher DB, Mondésert G, Vocat A, Lupien A, Sommer R, Vermet H, Lagrange S, Buechler J, Warner DF, McKinney JD, Pato J, Cole ST, Blundell TL, Rizzi M, Mizrahi V.

ACS Infect Dis. 2017 Jan 13;3(1):5-17. doi: 10.1021/acsinfecdis.6b00102. Epub 2016 Sep 8.


Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis.

Foo CS, Lechartier B, Kolly GS, Boy-Röttger S, Neres J, Rybniker J, Lupien A, Sala C, Piton J, Cole ST.

Antimicrob Agents Chemother. 2016 Oct 21;60(11):6451-6459. doi: 10.1128/AAC.01523-16. Print 2016 Nov.


Induced tigecycline resistance in Streptococcus pneumoniae mutants reveals mutations in ribosomal proteins and rRNA.

Lupien A, Gingras H, Leprohon P, Ouellette M.

J Antimicrob Chemother. 2015 Nov;70(11):2973-80. doi: 10.1093/jac/dkv211. Epub 2015 Jul 16.


Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae.

Dridi B, Lupien A, Bergeron MG, Leprohon P, Ouellette M.

Antimicrob Agents Chemother. 2015 Sep;59(9):5420-6. doi: 10.1128/AAC.00316-15. Epub 2015 Jun 22.


Multiple mutations and increased RNA expression in tetracycline-resistant Streptococcus pneumoniae as determined by genome-wide DNA and mRNA sequencing.

Lupien A, Gingras H, Bergeron MG, Leprohon P, Ouellette M.

J Antimicrob Chemother. 2015 Jul;70(7):1946-59. doi: 10.1093/jac/dkv060. Epub 2015 Apr 9.


Genomic characterization of ciprofloxacin resistance in a laboratory-derived mutant and a clinical isolate of Streptococcus pneumoniae.

Lupien A, Billal DS, Fani F, Soualhine H, Zhanel GG, Leprohon P, Ouellette M.

Antimicrob Agents Chemother. 2013 Oct;57(10):4911-9. doi: 10.1128/AAC.00418-13. Epub 2013 Jul 22.


Proteomic and transcriptomic analysis of linezolid resistance in Streptococcus pneumoniae.

Feng J, Billal DS, Lupien A, Racine G, Winstall E, Légaré D, Leprohon P, Ouellette M.

J Proteome Res. 2011 Oct 7;10(10):4439-52. doi: 10.1021/pr200221s. Epub 2011 Sep 13.


Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance.

Feng J, Lupien A, Gingras H, Wasserscheid J, Dewar K, Légaré D, Ouellette M.

Genome Res. 2009 Jul;19(7):1214-23. doi: 10.1101/gr.089342.108. Epub 2009 Apr 6.


Nurse anesthetists as university faculty.

Lupien AE, Rosenkoetter MM.

AANA J. 2006 Oct;74(5):366-72.


Rural nurse anesthesia practice: a pilot study.

Seibert EM, Alexander J, Lupien AE.

AANA J. 2004 Jun;72(3):181-90.


Limitations to self-care in the ambulatory surgical patient.

Lupien AE, Schoneboom BA, Wren KR.

J Perianesth Nurs. 2000 Apr;15(2):102-7.


The use of an anesthesia simulator in graduate and undergraduate education.

Monti EJ, Wren K, Haas R, Lupien AE.

CRNA. 1998 May;9(2):59-66.


Head off compartment syndrome before it's too late.

Lupien AE.

RN. 1980 Dec;43(12):38-41, 114. No abstract available.


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