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Items: 1 to 50 of 139

1.

Comprehensive kinome NGS targeted expression profiling by KING-REX.

Carapezza G, Cusi C, Rizzo E, Raddrizzani L, Di Bella S, Somaschini A, Leone A, Lupi R, Mutarelli M, Nigro V, di Bernardo D, Magni P, Isacchi A, Bosotti R.

BMC Genomics. 2019 Apr 23;20(1):307. doi: 10.1186/s12864-019-5676-3.

2.

Thermal treatment reduces gliadin recognition by IgE, but a subsequent digestion and epithelial crossing permits recovery.

Lupi R, Denery-Papini S, Claude M, Tranquet O, Drouet M, Masci S, Larré C.

Food Res Int. 2019 Apr;118:22-31. doi: 10.1016/j.foodres.2018.02.011. Epub 2018 Feb 9.

PMID:
30898348
3.

Digestion differently affects the ability of native and thermally aggregated ovalbumin to trigger basophil activation.

Claude M, Lupi R, Picariello G, Drouet M, Larré C, Denery-Papini S, Brossard C.

Food Res Int. 2019 Apr;118:108-114. doi: 10.1016/j.foodres.2017.11.040. Epub 2017 Nov 21.

PMID:
30898346
4.

Combined microwave processing and enzymatic proteolysis of bovine whey proteins: the impact on bovine β-lactoglobulin allergenicity.

El Mecherfi KE, Curet S, Lupi R, Larré C, Rouaud O, Choiset Y, Rabesona H, Haertlé T.

J Food Sci Technol. 2019 Jan;56(1):177-186. doi: 10.1007/s13197-018-3471-9. Epub 2018 Nov 8.

PMID:
30728559
5.

Wheat ATI CM3, CM16 and 0.28 Allergens Produced in Pichia Pastoris Display a Different Eliciting Potential in Food Allergy to Wheat .

Tundo S, Lupi R, Lafond M, Giardina T, Larré C, Denery-Papini S, Morisset M, Kalunke R, Sestili F, Masci S.

Plants (Basel). 2018 Nov 16;7(4). pii: E101. doi: 10.3390/plants7040101.

6.

Effects of Listening to Live Singing in Patients Undergoing Hemodialysis: A Randomized Controlled Crossover Study.

Burrai F, Lupi R, Luppi M, Micheluzzi V, Donati G, Lamanna G, Raghavan R.

Biol Res Nurs. 2019 Jan;21(1):30-38. doi: 10.1177/1099800418802638. Epub 2018 Sep 24.

PMID:
30249121
7.

Production and molecular characterization of bread wheat lines with reduced amount of α-type gliadins.

Camerlengo F, Sestili F, Silvestri M, Colaprico G, Margiotta B, Ruggeri R, Lupi R, Masci S, Lafiandra D.

BMC Plant Biol. 2017 Dec 19;17(1):248. doi: 10.1186/s12870-017-1211-3.

8.

Metabolic regulation of GLP-1 and PC1/3 in pancreatic α-cell line.

Sancho V, Daniele G, Lucchesi D, Lupi R, Ciccarone A, Penno G, Bianchi C, Dardano A, Miccoli R, Del Prato S.

PLoS One. 2017 Nov 9;12(11):e0187836. doi: 10.1371/journal.pone.0187836. eCollection 2017.

9.

Establishment and genomic characterization of the new chordoma cell line Chor-IN-1.

Bosotti R, Magnaghi P, Di Bella S, Cozzi L, Cusi C, Bozzi F, Beltrami N, Carapezza G, Ballinari D, Amboldi N, Lupi R, Somaschini A, Raddrizzani L, Salom B, Galvani A, Stacchiotti S, Tamborini E, Isacchi A.

Sci Rep. 2017 Aug 23;7(1):9226. doi: 10.1038/s41598-017-10044-3.

10.

How Proteins Aggregate Can Reduce Allergenicity: Comparison of Ovalbumins Heated under Opposite Electrostatic Conditions.

Claude M, Bouchaud G, Lupi R, Castan L, Tranquet O, Denery-Papini S, Bodinier M, Brossard C.

J Agric Food Chem. 2017 May 10;65(18):3693-3701. doi: 10.1021/acs.jafc.7b00676. Epub 2017 May 2.

PMID:
28434227
11.

Polyphenol Interactions Mitigate the Immunogenicity and Allergenicity of Gliadins.

Pérot M, Lupi R, Guyot S, Delayre-Orthez C, Gadonna-Widehem P, Thébaudin JY, Bodinier M, Larré C.

J Agric Food Chem. 2017 Aug 9;65(31):6442-6451. doi: 10.1021/acs.jafc.6b05371. Epub 2017 Mar 1.

PMID:
28190352
12.

The thermal aggregation of ovalbumin as large particles decreases its allergenicity for egg allergic patients and in a murine model.

Claude M, Lupi R, Bouchaud G, Bodinier M, Brossard C, Denery-Papini S.

Food Chem. 2016 Jul 15;203:136-144. doi: 10.1016/j.foodchem.2016.02.054. Epub 2016 Feb 10.

PMID:
26948598
13.

Neuroprotective coordination of cell mitophagy by the ATPase Inhibitory Factor 1.

Matic I, Cocco S, Ferraina C, Martin-Jimenez R, Florenzano F, Crosby J, Lupi R, Amadoro G, Russell C, Pignataro G, Annunziato L, Abramov AY, Campanella M.

Pharmacol Res. 2016 Jan;103:56-68. doi: 10.1016/j.phrs.2015.10.010. Epub 2015 Oct 17.

PMID:
26484591
14.

Assessment of the Allergenic Potential of Transgenic Wheat (Triticum aestivum) with Reduced Levels of ω5-Gliadins, the Major Sensitizing Allergen in Wheat-Dependent Exercise-Induced Anaphylaxis.

Altenbach SB, Tanaka CK, Pineau F, Lupi R, Drouet M, Beaudouin E, Morisset M, Denery-Papini S.

J Agric Food Chem. 2015 Oct 28;63(42):9323-32. doi: 10.1021/acs.jafc.5b03557. Epub 2015 Oct 16.

PMID:
26447559
15.

Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): A Potent, Orally Available, and Highly Selective PARP-1 Inhibitor for Cancer Therapy.

Papeo G, Posteri H, Borghi D, Busel AA, Caprera F, Casale E, Ciomei M, Cirla A, Corti E, D'Anello M, Fasolini M, Forte B, Galvani A, Isacchi A, Khvat A, Krasavin MY, Lupi R, Orsini P, Perego R, Pesenti E, Pezzetta D, Rainoldi S, Riccardi-Sirtori F, Scolaro A, Sola F, Zuccotto F, Felder ER, Donati D, Montagnoli A.

J Med Chem. 2015 Sep 10;58(17):6875-98. doi: 10.1021/acs.jmedchem.5b00680. Epub 2015 Aug 26.

PMID:
26222319
16.

Structural Basis of IgE Binding to α- and γ-Gliadins: Contribution of Disulfide Bonds and Repetitive and Nonrepetitive Domains.

Mameri H, Brossard C, Gaudin JC, Gohon Y, Paty E, Beaudouin E, Moneret-Vautrin DA, Drouet M, Solé V, Wien F, Lupi R, Larré C, Snégaroff J, Denery-Papini S.

J Agric Food Chem. 2015 Jul 29;63(29):6546-54. doi: 10.1021/acs.jafc.5b01922. Epub 2015 Jul 17.

PMID:
26186140
17.

Characterization of Antibodies and Development of an Indirect Competitive Immunoassay for Detection of Deamidated Gluten.

Tranquet O, Lupi R, Echasserieau-Laporte V, Pietri M, Larré C, Denery-Papini S.

J Agric Food Chem. 2015 Jun 10;63(22):5403-9. doi: 10.1021/acs.jafc.5b00923. Epub 2015 Jun 2.

PMID:
25980542
18.

Allergen relative abundance in several wheat varieties as revealed via a targeted quantitative approach using MS.

Rogniaux H, Pavlovic M, Lupi R, Lollier V, Joint M, Mameri H, Denery S, Larré C.

Proteomics. 2015 May;15(10):1736-45. doi: 10.1002/pmic.201400416.

PMID:
25764008
19.

Optimization of diarylthiazole B-raf inhibitors: identification of a compound endowed with high oral antitumor activity, mitigated hERG inhibition, and low paradoxical effect.

Pulici M, Traquandi G, Marchionni C, Modugno M, Lupi R, Amboldi N, Casale E, Colombo N, Corti L, Fasolini M, Gasparri F, Pastori W, Scolaro A, Donati D, Felder E, Galvani A, Isacchi A, Pesenti E, Ciomei M.

ChemMedChem. 2015 Feb;10(2):276-95. doi: 10.1002/cmdc.201402424. Epub 2014 Nov 27.

PMID:
25430902
20.

Insights into PARP Inhibitors' Selectivity Using Fluorescence Polarization and Surface Plasmon Resonance Binding Assays.

Papeo G, Avanzi N, Bettoni S, Leone A, Paolucci M, Perego R, Quartieri F, Riccardi-Sirtori F, Thieffine S, Montagnoli A, Lupi R.

J Biomol Screen. 2014 Sep;19(8):1212-9. doi: 10.1177/1087057114538319. Epub 2014 Jun 10.

PMID:
24916412
21.

Cell metabolism sets the differences between subpopulations of satellite cells (SCs).

Repele A, Lupi R, Eaton S, Urbani L, De Coppi P, Campanella M.

BMC Cell Biol. 2013 May 3;14:24. doi: 10.1186/1471-2121-14-24.

22.

How much does transgenesis affect wheat allergenicity?: Assessment in two GM lines over-expressing endogenous genes.

Lupi R, Denery-Papini S, Rogniaux H, Lafiandra D, Rizzi C, De Carli M, Moneret-Vautrin DA, Masci S, Larré C.

J Proteomics. 2013 Mar 27;80:281-91. doi: 10.1016/j.jprot.2013.01.028. Epub 2013 Feb 9.

PMID:
23403254
23.

A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

Marchetti P, Lupi R, Bugliani M, Kirkpatrick CL, Sebastiani G, Grieco FA, Del Guerra S, D'Aleo V, Piro S, Marselli L, Boggi U, Filipponi F, Tinti L, Salvini L, Wollheim CB, Purrello F, Dotta F.

Diabetologia. 2012 Dec;55(12):3262-72. doi: 10.1007/s00125-012-2716-9. Epub 2012 Sep 11.

PMID:
22965295
24.

Evidence for a role of frataxin in pancreatic islets isolated from multi-organ donors with and without type 2 diabetes mellitus.

Del Guerra S, D'Aleo V, Gualtierotti G, Pandolfi R, Boggi U, Vistoli F, Barnini S, Filipponi F, Del Prato S, Lupi R.

Horm Metab Res. 2012 Jun;44(6):471-5. doi: 10.1055/s-0032-1301920. Epub 2012 Mar 7.

PMID:
22399236
25.

Altered insulin receptor signalling and β-cell cycle dynamics in type 2 diabetes mellitus.

Folli F, Okada T, Perego C, Gunton J, Liew CW, Akiyama M, D'Amico A, La Rosa S, Placidi C, Lupi R, Marchetti P, Sesti G, Hellerstein M, Perego L, Kulkarni RN.

PLoS One. 2011;6(11):e28050. doi: 10.1371/journal.pone.0028050. Epub 2011 Nov 30.

26.

MitoZoa 2.0: a database resource and search tools for comparative and evolutionary analyses of mitochondrial genomes in Metazoa.

D'Onorio de Meo P, D'Antonio M, Griggio F, Lupi R, Borsani M, Pavesi G, Castrignanò T, Pesole G, Gissi C.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1168-72. doi: 10.1093/nar/gkr1144. Epub 2011 Nov 28.

27.

Identification of candidate substrates for poly(ADP-ribose) polymerase-2 (PARP2) in the absence of DNA damage using high-density protein microarrays.

Troiani S, Lupi R, Perego R, Depaolini SR, Thieffine S, Bosotti R, Rusconi L.

FEBS J. 2011 Oct;278(19):3676-87. doi: 10.1111/j.1742-4658.2011.08286.x. Epub 2011 Sep 6.

28.

Glucagon-like peptide-1 secretion in women with gestational diabetes mellitus during and after pregnancy.

Lencioni C, Resi V, Romero F, Lupi R, Volpe L, Bertolotto A, Ghio A, Del Prato S, Marchetti P, Di Cianni G.

J Endocrinol Invest. 2011 Oct;34(9):e287-90. doi: 10.3275/7799. Epub 2011 Jun 7.

PMID:
21666414
29.

Assessment of allergenicity of diploid and hexaploid wheat genotypes: identification of allergens in the albumin/globulin fraction.

Larré C, Lupi R, Gombaud G, Brossard C, Branlard G, Moneret-Vautrin DA, Rogniaux H, Denery-Papini S.

J Proteomics. 2011 Aug 12;74(8):1279-89. doi: 10.1016/j.jprot.2011.03.014. Epub 2011 Apr 5.

PMID:
21473946
30.

Neutralizing interleukin-1beta (IL-1beta) induces beta-cell survival by maintaining PDX1 protein nuclear localization.

Ardestani A, Sauter NS, Paroni F, Dharmadhikari G, Cho JH, Lupi R, Marchetti P, Oberholzer J, Conte JK, Maedler K.

J Biol Chem. 2011 May 13;286(19):17144-55. doi: 10.1074/jbc.M110.210526. Epub 2011 Mar 10. Retraction in: Ardestani A, Sauter NS, Paroni F, Dharmadhikari G, Cho JH, Lupi R, Marchetti P, Oberholzer J, Kerr Conte J, Maedler K. J Biol Chem. 2015 Nov 13;290(46):27532.

31.

Direct effects of rapid-acting insulin analogues on insulin signaling in human pancreatic islets in vitro.

D'Aleo V, Mancarella R, Del Guerra S, Boggi U, Filipponi F, Marchetti P, Lupi R.

Diabetes Metab. 2011 Sep;37(4):324-9. doi: 10.1016/j.diabet.2010.12.002. Epub 2011 Feb 26.

PMID:
21354844
32.

INS VNTR class genotype and the function of isolated human islets.

D'Aleo V, Del Guerra S, Groves C, Lupi R, Tancredi M, McCarthy M, Marchetti P.

Nutr Metab Cardiovasc Dis. 2011 Mar;21(3):e9-11. doi: 10.1016/j.numecd.2010.10.005. Epub 2010 Dec 30. No abstract available.

PMID:
21193298
33.

Functional and survival analysis of isolated human islets.

D'Aleo V, Del Guerra S, Gualtierotti G, Filipponi F, Boggi U, De Simone P, Vistoli F, Del Prato S, Marchetti P, Lupi R.

Transplant Proc. 2010 Jul-Aug;42(6):2250-1. doi: 10.1016/j.transproceed.2010.05.132.

PMID:
20692456
34.

A common polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene regulatory region influences MCP-1 expression and function of isolated human pancreatic islets.

Del Guerra S, D'Aleo V, Gualtierotti G, Filipponi F, Boggi U, De Simone P, Vistoli F, Del Prato S, Marchetti P, Lupi R.

Transplant Proc. 2010 Jul-Aug;42(6):2247-9. doi: 10.1016/j.transproceed.2010.05.039.

PMID:
20692455
35.

The direct effects of GLP-1 and GIP, alone or in combination, on human pancreatic islets.

Lupi R, Del Guerra S, D'Aleo V, Boggi U, Filipponi F, Marchetti P.

Regul Pept. 2010 Dec 10;165(2-3):129-32. doi: 10.1016/j.regpep.2010.04.009. Epub 2010 May 20.

PMID:
20472004
36.

The beta-cell in human type 2 diabetes.

Marchetti P, Lupi R, Del Guerra S, Bugliani M, Marselli L, Boggi U.

Adv Exp Med Biol. 2010;654:501-14. doi: 10.1007/978-90-481-3271-3_22. Review.

PMID:
20217512
37.

Meta-analysis and functional effects of the SLC30A8 rs13266634 polymorphism on isolated human pancreatic islets.

Cauchi S, Del Guerra S, Choquet H, D'Aleo V, Groves CJ, Lupi R, McCarthy MI, Froguel P, Marchetti P.

Mol Genet Metab. 2010 May;100(1):77-82. doi: 10.1016/j.ymgme.2010.01.001. Epub 2010 Jan 15.

PMID:
20138556
38.

MitoZoa: a curated mitochondrial genome database of metazoans for comparative genomics studies.

Lupi R, de Meo PD, Picardi E, D'Antonio M, Paoletti D, Castrignanò T, Pesole G, Gissi C.

Mitochondrion. 2010 Mar;10(2):192-9. doi: 10.1016/j.mito.2010.01.004. Epub 2010 Jan 18.

PMID:
20080208
39.

Goals of treatment for type 2 diabetes: beta-cell preservation for glycemic control.

Marchetti P, Lupi R, Del Guerra S, Bugliani M, D'Aleo V, Occhipinti M, Boggi U, Marselli L, Masini M.

Diabetes Care. 2009 Nov;32 Suppl 2:S178-83. doi: 10.2337/dc09-S306. Review. No abstract available.

40.

G-protein-coupled receptor 40 (GPR40) expression and its regulation in human pancreatic islets: the role of type 2 diabetes and fatty acids.

Del Guerra S, Bugliani M, D'Aleo V, Del Prato S, Boggi U, Mosca F, Filipponi F, Lupi R.

Nutr Metab Cardiovasc Dis. 2010 Jan;20(1):22-5. doi: 10.1016/j.numecd.2009.02.008. Epub 2009 Sep 15.

PMID:
19758793
41.

Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

Cunha DA, Ladrière L, Ortis F, Igoillo-Esteve M, Gurzov EN, Lupi R, Marchetti P, Eizirik DL, Cnop M.

Diabetes. 2009 Dec;58(12):2851-62. doi: 10.2337/db09-0685. Epub 2009 Aug 31.

42.

A role for autophagy in β-cell life and death.

Masini M, Lupi R, Bugliani M, Boggi U, Filipponi F, Masiello P, Marchetti P.

Islets. 2009 Sep-Oct;1(2):157-9. doi: 10.4161/isl.1.2.9372.

PMID:
21099265
43.

Calpain-10 expression is elevated in pancreatic islets from patients with type 2 diabetes.

Ling C, Groop L, Guerra SD, Lupi R.

PLoS One. 2009 Aug 18;4(8):e6558. doi: 10.1371/journal.pone.0006558.

44.

Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide.

Del Guerra S, D'Aleo V, Lupi R, Masini M, Bugliani M, Boggi U, Filipponi F, Marchetti P.

Diabetes Metab. 2009 Sep;35(4):293-8. doi: 10.1016/j.diabet.2009.01.004. Epub 2009 Jun 6.

PMID:
19502091
45.

The non-peptidyl low molecular weight radical scavenger IAC protects human pancreatic islets from lipotoxicity.

D'Aleo V, Del Guerra S, Martano M, Bonamassa B, Canistro D, Soleti A, Valgimigli L, Paolini M, Filipponi F, Boggi U, Del Prato S, Lupi R.

Mol Cell Endocrinol. 2009 Oct 15;309(1-2):63-6. doi: 10.1016/j.mce.2009.05.010. Epub 2009 May 27.

PMID:
19481137
46.

Autophagy in human type 2 diabetes pancreatic beta cells.

Masini M, Bugliani M, Lupi R, del Guerra S, Boggi U, Filipponi F, Marselli L, Masiello P, Marchetti P.

Diabetologia. 2009 Jun;52(6):1083-6. doi: 10.1007/s00125-009-1347-2. Epub 2009 Apr 15.

PMID:
19367387
47.

Perilipin is present in islets of Langerhans and protects against lipotoxicity when overexpressed in the beta-cell line INS-1.

Borg J, Klint C, Wierup N, Ström K, Larsson S, Sundler F, Lupi R, Marchetti P, Xu G, Kimmel A, Londos C, Holm C.

Endocrinology. 2009 Jul;150(7):3049-57. doi: 10.1210/en.2008-0913. Epub 2009 Mar 19.

48.

Glucose transporter 2 gene polymorphisms and beta-cell function in isolated human pancreatic islets.

Del Guerra S, Lupi R, D'Aleo V, Filipponi F, Boggi U, Marchetti P.

Diabetes Metab. 2009 Apr;35(2):155-6. doi: 10.1016/j.diabet.2009.01.002. Epub 2009 Mar 9. No abstract available.

PMID:
19269875
49.

Beneficial effect of the nonpeptidyl low molecular weight radical scavenger IAC on cultured human islet function.

Mancarella R, Del Guerra S, Masini M, Bugliani M, Valgimigli L, Pedulli GF, Paolini M, Canistro D, Armando A, Soleti A, Filipponi F, Mosca F, Boggi U, Del Prato S, Marchetti P, Lupi R.

Cell Transplant. 2008;17(10-11):1271-6.

PMID:
19181220
50.

Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression.

Serre-Beinier V, Bosco D, Zulianello L, Charollais A, Caille D, Charpantier E, Gauthier BR, Diaferia GR, Giepmans BN, Lupi R, Marchetti P, Deng S, Buhler L, Berney T, Cirulli V, Meda P.

Hum Mol Genet. 2009 Feb 1;18(3):428-39. doi: 10.1093/hmg/ddn370. Epub 2008 Nov 10.

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