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Items: 6


Phenotypic rescue of a Drosophila model of mitochondrial ANT1 disease.

Vartiainen S, Chen S, George J, Tuomela T, Luoto KR, O'Dell KM, Jacobs HT.

Dis Model Mech. 2014 Jun;7(6):635-48. doi: 10.1242/dmm.016527. Epub 2014 May 8.


Tumor hypoxia as a driving force in genetic instability.

Luoto KR, Kumareswaran R, Bristow RG.

Genome Integr. 2013 Oct 24;4(1):5. doi: 10.1186/2041-9414-4-5.


PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy.

Fraser M, Zhao H, Luoto KR, Lundin C, Coackley C, Chan N, Joshua AM, Bismar TA, Evans A, Helleday T, Bristow RG.

Clin Cancer Res. 2012 Feb 15;18(4):1015-27. doi: 10.1158/1078-0432.CCR-11-2189. Epub 2011 Nov 23. Erratum in: Clin Cancer Res. 2012 May 1;18(9):2720.


The receptor tyrosine kinase inhibitor amuvatinib (MP470) sensitizes tumor cells to radio- and chemo-therapies in part by inhibiting homologous recombination.

Zhao H, Luoto KR, Meng AX, Bristow RG.

Radiother Oncol. 2011 Oct;101(1):59-65. doi: 10.1016/j.radonc.2011.08.013. Epub 2011 Sep 6.


Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair.

Luoto KR, Meng AX, Wasylishen AR, Zhao H, Coackley CL, Penn LZ, Bristow RG.

Cancer Res. 2010 Nov 1;70(21):8748-59. doi: 10.1158/0008-5472.CAN-10-0944. Epub 2010 Oct 12.


Contextual synthetic lethality of cancer cell kill based on the tumor microenvironment.

Chan N, Pires IM, Bencokova Z, Coackley C, Luoto KR, Bhogal N, Lakshman M, Gottipati P, Oliver FJ, Helleday T, Hammond EM, Bristow RG.

Cancer Res. 2010 Oct 15;70(20):8045-54. doi: 10.1158/0008-5472.CAN-10-2352. Epub 2010 Oct 5.

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