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Items: 18


Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers.

Hatzivassiliou G, Haling JR, Chen H, Song K, Price S, Heald R, Hewitt JF, Zak M, Peck A, Orr C, Merchant M, Hoeflich KP, Chan J, Luoh SM, Anderson DJ, Ludlam MJ, Wiesmann C, Ultsch M, Friedman LS, Malek S, Belvin M.

Nature. 2013 Sep 12;501(7466):232-6. doi: 10.1038/nature12441. Epub 2013 Aug 11. Erratum in: Nature. 2013 Oct 10;502(7470):258.


GeneHub-GEPIS: digital expression profiling for normal and cancer tissues based on an integrated gene database.

Zhang Y, Luoh SM, Hon LS, Baertsch R, Wood WI, Zhang Z.

Nucleic Acids Res. 2007 Jul;35(Web Server issue):W152-8. Epub 2007 Jun 1.


Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus.

Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RA, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ.

Mol Cell Biol. 2005 Aug;25(16):7054-68.


GEPIS--quantitative gene expression profiling in normal and cancer tissues.

Zhang Y, Eberhard DA, Frantz GD, Dowd P, Wu TD, Zhou Y, Watanabe C, Luoh SM, Polakis P, Hillan KJ, Wood WI, Zhang Z.

Bioinformatics. 2004 Oct 12;20(15):2390-8. Epub 2004 Apr 8.


Genome-wide identification of chromosomal regions of increased tumor expression by transcriptome analysis.

Zhou Y, Luoh SM, Zhang Y, Watanabe C, Wu TD, Ostland M, Wood WI, Zhang Z.

Cancer Res. 2003 Sep 15;63(18):5781-4.


Gli regulation by the opposing activities of fused and suppressor of fused.

Murone M, Luoh SM, Stone D, Li W, Gurney A, Armanini M, Grey C, Rosenthal A, de Sauvage FJ.

Nat Cell Biol. 2000 May;2(5):310-2. No abstract available.


Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo.

Luoh SM, Stefanich E, Solar G, Steinmetz H, Lipari T, Pestina TI, Jackson CW, de Sauvage FJ.

Mol Cell Biol. 2000 Jan;20(2):507-15.


Activating Smoothened mutations in sporadic basal-cell carcinoma.

Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, de Sauvage FJ.

Nature. 1998 Jan 1;391(6662):90-2.


Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin.

Luoh SM, Di Marco F, Levin N, Armanini M, Xie MH, Nelson C, Bennett GL, Williams M, Spencer SA, Gurney A, de Sauvage FJ.

J Mol Endocrinol. 1997 Feb;18(1):77-85.


Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.

Carver-Moore K, Broxmeyer HE, Luoh SM, Cooper S, Peng J, Burstein SA, Moore MW, de Sauvage FJ.

Blood. 1996 Aug 1;88(3):803-8.


The bglX gene located at 47.8 min on the Escherichia coli chromosome encodes a periplasmic beta-glucosidase.

Yang M, Luoh SM, Goddard A, Reilly D, Henzel W, Bass S.

Microbiology. 1996 Jul;142 ( Pt 7):1659-65.


Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1988-92.


Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin.

de Sauvage FJ, Carver-Moore K, Luoh SM, Ryan A, Dowd M, Eaton DL, Moore MW.

J Exp Med. 1996 Feb 1;183(2):651-6.


Mutations of the growth hormone receptor in children with idiopathic short stature. The Growth Hormone Insensitivity Study Group.

Goddard AD, Covello R, Luoh SM, Clackson T, Attie KM, Gesundheit N, Rundle AC, Wells JA, Carlsson LM.

N Engl J Med. 1995 Oct 26;333(17):1093-8.


Isolation of cDNA clones encoding the mouse protein V-1.

Pennica D, Shaw KJ, Luoh SM, Wood WI.

Gene. 1995 Jun 9;158(2):305-6.


Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy.

Pennica D, King KL, Shaw KJ, Luis E, Rullamas J, Luoh SM, Darbonne WC, Knutzon DS, Yen R, Chien KR, et al.

Proc Natl Acad Sci U S A. 1995 Feb 14;92(4):1142-6.


Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene.

Lee J, Wang Z, Luoh SM, Wood WI, Scadden DT.

Gene. 1994 Jan 28;138(1-2):247-51.


Hemagglutinin mutations related to antigenic variation in H1 swine influenza viruses.

Luoh SM, McGregor MW, Hinshaw VS.

J Virol. 1992 Feb;66(2):1066-73.

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