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Items: 6


Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.

Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM.

Cancer Discov. 2012 Nov;2(11):1048-63. doi: 10.1158/2159-8290.CD-11-0336. Epub 2012 Aug 22.


EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumors.

Evans CH, Liu F, Porter RM, O'Sullivan RP, Merghoub T, Lunsford EP, Robichaud K, Van Valen F, Lessnick SL, Gebhardt MC, Wells JW.

Clin Cancer Res. 2012 Oct 1;18(19):5341-51. doi: 10.1158/1078-0432.CCR-12-1985. Epub 2012 Aug 9.


Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex.

Liu F, Lunsford EP, Tong J, Ashitate Y, Gibbs SL, Yu J, Choi HS, Henske EP, Frangioni JV.

PLoS One. 2012;7(6):e38589. doi: 10.1371/journal.pone.0038589. Epub 2012 Jun 15.


Mice with a targeted deletion of the type 2 deiodinase are insulin resistant and susceptible to diet induced obesity.

Marsili A, Aguayo-Mazzucato C, Chen T, Kumar A, Chung M, Lunsford EP, Harney JW, Van-Tran T, Gianetti E, Ramadan W, Chou C, Bonner-Weir S, Larsen PR, Silva JE, Zavacki AM.

PLoS One. 2011;6(6):e20832. doi: 10.1371/journal.pone.0020832. Epub 2011 Jun 16.


High-resolution computed tomography of single breast cancer microcalcifications in vivo.

Inoue K, Liu F, Hoppin J, Lunsford EP, Lackas C, Hesterman J, Lenkinski RE, Fujii H, Frangioni JV.

Mol Imaging. 2011 Aug;10(4):295-304. doi: 10.2310/7290.2010.00050. Epub 2011 Apr 1.


A dose- and time-controllable syngeneic animal model of breast cancer microcalcification.

Liu F, Misra P, Lunsford EP, Vannah JT, Liu Y, Lenkinski RE, Frangioni JV.

Breast Cancer Res Treat. 2010 Jul;122(1):87-94. doi: 10.1007/s10549-009-0535-6. Epub 2009 Sep 17.

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