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Neuropathies and paraproteins.

Lunn MP.

Curr Opin Neurol. 2019 Jul 15. doi: 10.1097/WCO.0000000000000726. [Epub ahead of print]


High-dose therapy and autologous transplantation for POEMS Syndrome: effective, but how to optimise?

Tomkins O, Keddie S, Lunn MP, D'Sa S.

Br J Haematol. 2019 Jun 18. doi: 10.1111/bjh.16057. [Epub ahead of print] No abstract available.


A digital health research platform for community engagement, recruitment, and retention of sexual and gender minority adults in a national longitudinal cohort study--The PRIDE Study.

Lunn MR, Lubensky M, Hunt C, Flentje A, Capriotti MR, Sooksaman C, Harnett T, Currie D, Neal C, Obedin-Maliver J.

J Am Med Inform Assoc. 2019 Jun 4. pii: ocz082. doi: 10.1093/jamia/ocz082. [Epub ahead of print]


Implementing Evidence-Based Guidelines for Falls Prevention: Observations of Nursing Activities During the Care of Older People With Cognitive Impairment.

Grealish L, Real B, Todd JA, Darch J, Soltau D, Phelan M, Lunn M, Brandis S, Cooke M, Chaboyer W.

Worldviews Evid Based Nurs. 2019 Jun 3. doi: 10.1111/wvn.12376. [Epub ahead of print]


Advancing Equity in Nephrology: Enhancing Care for LGBTQ+ Patients and Our Workforce.

Mohottige D, Lunn MR.

Clin J Am Soc Nephrol. 2019 Jul 5;14(7):1094-1096. doi: 10.2215/CJN.01950219. Epub 2019 May 22. No abstract available.


CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study.

Cunningham EL, McGuinness B, McAuley DF, Toombs J, Mawhinney T, O'Brien S, Beverland D, Schott JM, Lunn MP, Zetterberg H, Passmore AP.

Ann Surg. 2019 Jun;269(6):1200-1205. doi: 10.1097/SLA.0000000000002684.


Using mobile technology to engage sexual and gender minorities in clinical research.

Lunn MR, Capriotti MR, Flentje A, Bibbins-Domingo K, Pletcher MJ, Triano AJ, Sooksaman C, Frazier J, Obedin-Maliver J.

PLoS One. 2019 May 2;14(5):e0216282. doi: 10.1371/journal.pone.0216282. eCollection 2019.


Correction: The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J, Heslegrave A, Zetterberg H, Lunn MP, Rommer PS, Grossmann A, Sharshar T, Richter G, Nöldge-Schomburg G, Sauer M.

PLoS One. 2019 Feb 20;14(2):e0212830. doi: 10.1371/journal.pone.0212830. eCollection 2019.


Frequent central nervous system, pachymeningeal and plexus MRI changes in POEMS syndrome.

Ziff OJ, Hoskote C, Keddie S, D'Sa S, Davangnanam I, Lunn MPT.

J Neurol. 2019 May;266(5):1067-1072. doi: 10.1007/s00415-019-09233-z. Epub 2019 Feb 12.


Coupled virus - bacteria interactions and ecosystem function in an engineered microbial system.

Brown MR, Baptista JC, Lunn M, Swan DL, Smith SJ, Davenport RJ, Allen BD, Sloan WT, Curtis TP.

Water Res. 2019 Apr 1;152:264-273. doi: 10.1016/j.watres.2019.01.003. Epub 2019 Jan 11.


The prognostic value of neurofilament levels in patients with sepsis-associated encephalopathy - A prospective, pilot observational study.

Ehler J, Petzold A, Wittstock M, Kolbaske S, Gloger M, Henschel J, Heslegrave A, Zetterberg H, Lunn MP, Rommer PS, Grossmann A, Sharshar T, Richter G, Nöldge-Schomburg G, Sauer M.

PLoS One. 2019 Jan 24;14(1):e0211184. doi: 10.1371/journal.pone.0211184. eCollection 2019. Erratum in: PLoS One. 2019 Feb 20;14(2):e0212830.


Diagnosis of amyloid neuropathy.

Kapoor M, Rossor AM, Jaunmuktane Z, Lunn MPT, Reilly MM.

Pract Neurol. 2019 Jun;19(3):250-258. doi: 10.1136/practneurol-2018-002098. Epub 2018 Dec 30.


Complexity of the Genetics and Clinical Presentation of Spinocerebellar Ataxia 17.

Nethisinghe S, Lim WN, Ging H, Zeitlberger A, Abeti R, Pemble S, Sweeney MG, Labrum R, Cervera C, Houlden H, Rosser E, Limousin P, Kennedy A, Lunn MP, Bhatia KP, Wood NW, Hardy J, Polke JM, Veneziano L, Brusco A, Davis MB, Giunti P.

Front Cell Neurosci. 2018 Nov 23;12:429. doi: 10.3389/fncel.2018.00429. eCollection 2018.


Caring for the older person with cognitive impairment in hospital: Qualitative analysis of nursing personnel reflections on fall events.

Grealish L, Chaboyer W, Darch J, Real B, Phelan M, Soltau D, Lunn M, Brandis S, Todd JA, Cooke M.

J Clin Nurs. 2019 Apr;28(7-8):1346-1353. doi: 10.1111/jocn.14724. Epub 2019 Jan 8.


Advances in POEMS treatment and the need to define standardised outcome measures.

Keddie S, D'Sa S, Lunn MP.

Br J Haematol. 2019 Apr;185(2):386-388. doi: 10.1111/bjh.15529. Epub 2018 Oct 29. No abstract available.


Prevalence and Course of Endocrinopathy in POEMS Syndrome.

Caimari F, Keddie S, Lunn MP, D'Sa S, Baldeweg SE.

J Clin Endocrinol Metab. 2019 Jun 1;104(6):2140-2146. doi: 10.1210/jc.2018-01516.


Use of intravenous immunoglobulin for the treatment of autoimmune encephalitis: audit of the NHS experience.

Kinsella JA, Irani SR, Hollingsworth R, O'Shaughnessy D, Kane P, Foster M, Schott JM, Lunn MP.

JRSM Open. 2018 Sep 3;9(9):2054270418793021. doi: 10.1177/2054270418793021. eCollection 2018 Sep.


Raised VEGF: High sensitivity and specificity in the diagnosis of POEMS syndrome.

Pihan M, Keddie S, D'Sa S, Church AJ, Yong KL, Reilly MM, Lunn MP.

Neurol Neuroimmunol Neuroinflamm. 2018 Aug 15;5(5):e486. doi: 10.1212/NXI.0000000000000486. eCollection 2018 Sep.


Genetic Counselors' and Genetic Counseling Students' Implicit and Explicit Attitudes toward Homosexuality.

Nathan ML, Ormond KE, Dial CM, Gamma A, Lunn MR.

J Genet Couns. 2019 Feb;28(1):91-101. doi: 10.1007/s10897-018-0295-8. Epub 2019 Jan 16.


POEMS syndrome.

Keddie S, Lunn MP.

Curr Opin Neurol. 2018 Oct;31(5):551-558. doi: 10.1097/WCO.0000000000000610. Review.


The new era of precision population health: insights for the All of Us Research Program and beyond.

Lyles CR, Lunn MR, Obedin-Maliver J, Bibbins-Domingo K.

J Transl Med. 2018 Jul 27;16(1):211. doi: 10.1186/s12967-018-1585-5.


Plasma cell depletion with bortezomib in the treatment of refractory N-methyl-d-aspartate (NMDA) receptor antibody encephalitis. Rational developments in neuroimmunological treatment.

Keddie S, Crisp SJ, Blackaby J, Cox A, Coles A, Hart M, Church AJ, Vincent A, Zandi M, Lunn MP.

Eur J Neurol. 2018 Nov;25(11):1384-1388. doi: 10.1111/ene.13759. Epub 2018 Aug 31.


Amyloid β peptides are differentially vulnerable to preanalytical surface exposure, an effect incompletely mitigated by the use of ratios.

Toombs J, Foiani MS, Wellington H, Paterson RW, Arber C, Heslegrave A, Lunn MP, Schott JM, Wray S, Zetterberg H.

Alzheimers Dement (Amst). 2018 Mar 22;10:311-321. doi: 10.1016/j.dadm.2018.02.005. eCollection 2018.


[18F]Florbetaben PET-CT confirms AL amyloidosis in a patient with Waldenström's Macroglobulinemia.

Fox TA, Lunn M, Wechalekar A, Bomanji J, Wan S, D'Sa S.

Haematologica. 2018 Jul;103(7):e322-e324. doi: 10.3324/haematol.2017.184515. Epub 2018 Apr 12. No abstract available.


Cerebrospinal fluid in the differential diagnosis of Alzheimer's disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic.

Paterson RW, Slattery CF, Poole T, Nicholas JM, Magdalinou NK, Toombs J, Chapman MD, Lunn MP, Heslegrave AJ, Foiani MS, Weston PSJ, Keshavan A, Rohrer JD, Rossor MN, Warren JD, Mummery CJ, Blennow K, Fox NC, Zetterberg H, Schott JM.

Alzheimers Res Ther. 2018 Mar 20;10(1):32. doi: 10.1186/s13195-018-0361-3.


POEMS neuropathy: optimising diagnosis and management.

Keddie S, D'Sa S, Foldes D, Carr AS, Reilly MM, Lunn MPT.

Pract Neurol. 2018 Aug;18(4):278-290. doi: 10.1136/practneurol-2017-001792. Epub 2018 Mar 6. Review.


CSF Beta-amyloid 1-42 Concentration Predicts Delirium Following Elective Arthroplasty Surgery in an Observational Cohort Study.

Cunningham EL, McGuinness B, McAuley DF, Toombs J, Mawhinney T, O'Brien S, Beverland D, Schott JM, Lunn MP, Zetterberg H, Passmore AP.

Ann Surg. 2018 Feb 2. doi: 10.1097/SLA.0000000000002684. [Epub ahead of print]


A diagnostic conundrum.

Keddie S, Jaunmuktane Z, Brandner S, Shah S, Maddison P, Rees JH, Hanna MG, Lunn MPT, Reilly MM, Rossor AM, Carr AS.

Pract Neurol. 2018 Apr;18(2):137-142. doi: 10.1136/practneurol-2017-001801. Epub 2018 Jan 23. No abstract available.


High prevalence of the MYD88 L265P mutation in IgM anti-MAG paraprotein-associated peripheral neuropathy.

Vos JM, Notermans NC, D'Sa S, Lunn MP, van der Pol WL, Kraan W, Reilly MM, Chalker J, Gupta R, Kersten MJ, Pals ST, Minnema MC.

J Neurol Neurosurg Psychiatry. 2018 Sep;89(9):1007-1009. doi: 10.1136/jnnp-2017-316689. Epub 2017 Oct 10. No abstract available.


230th ENMC International Workshop:: Improving future assessment and research in IgM anti-MAG peripheral neuropathy: A consensus collaborative effort, Naarden, The Netherlands, 24-26 February 2017.

Pruppers MHJ, Merkies ISJ, Lunn MPT, Notermans NC; IMAGiNe Study Group.

Neuromuscul Disord. 2017 Nov;27(11):1065-1072. doi: 10.1016/j.nmd.2017.08.001. Epub 2017 Aug 2. No abstract available.


The predictive value of T-tau and AB1-42 levels in idiopathic normal pressure hydrocephalus.

Craven CL, Baudracco I, Zetterberg H, Lunn MPT, Chapman MD, Lakdawala N, Watkins LD, Toma AK.

Acta Neurochir (Wien). 2017 Dec;159(12):2293-2300. doi: 10.1007/s00701-017-3314-x. Epub 2017 Sep 9.


Sociodemographic Characteristics and Health Outcomes Among Lesbian, Gay, and Bisexual U.S. Adults Using Healthy People 2020 Leading Health Indicators.

Lunn MR, Cui W, Zack MM, Thompson WW, Blank MB, Yehia BR.

LGBT Health. 2017 Aug;4(4):283-294. doi: 10.1089/lgbt.2016.0087. Epub 2017 Jul 20.


Genetic and clinical characteristics of NEFL-related Charcot-Marie-Tooth disease.

Horga A, Laurà M, Jaunmuktane Z, Jerath NU, Gonzalez MA, Polke JM, Poh R, Blake JC, Liu YT, Wiethoff S, Bettencourt C, Lunn MP, Manji H, Hanna MG, Houlden H, Brandner S, Züchner S, Shy M, Reilly MM.

J Neurol Neurosurg Psychiatry. 2017 Jul;88(7):575-585. doi: 10.1136/jnnp-2016-315077. Epub 2017 May 13.


Estimating the Prevalence of Sexual Minority Adolescents.

Lunn MR, Obedin-Maliver J, Bibbins-Domingo K.

JAMA. 2017 Apr 25;317(16):1691-1692. doi: 10.1001/jama.2017.2918. No abstract available.


Applying Organizational Change to Promote Lesbian, Gay, Bisexual, and Transgender Inclusion and Reduce Health Disparities.

Eckstrand KL, Lunn MR, Yehia BR.

LGBT Health. 2017 Jun;4(3):174-180. doi: 10.1089/lgbt.2015.0148. Epub 2017 Mar 15. Review.


Investigation and management of IgM and Waldenström-associated peripheral neuropathies: recommendations from the IWWM-8 consensus panel.

D'Sa S, Kersten MJ, Castillo JJ, Dimopoulos M, Kastritis E, Laane E, Leblond V, Merlini G, Treon SP, Vos JM, Lunn MP.

Br J Haematol. 2017 Mar;176(5):728-742. doi: 10.1111/bjh.14492. Epub 2017 Feb 15.


Treatments for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): an overview of systematic reviews.

Oaklander AL, Lunn MP, Hughes RA, van Schaik IN, Frost C, Chalk CH.

Cochrane Database Syst Rev. 2017 Jan 13;1:CD010369. doi: 10.1002/14651858.CD010369.pub2. Review.


Effect of Spinal Manometers on Cerebrospinal Fluid Amyloid-β Concentration.

Toombs J, Foiani MS, Paterson RW, Heslegrave A, Wray S, Schott JM, Fox NC, Lunn MP, Blennow K, Zetterberg H.

J Alzheimers Dis. 2017;56(3):885-891. doi: 10.3233/JAD-161126.


Inhibition of complement in Guillain-Barré syndrome: the ICA-GBS study.

Davidson AI, Halstead SK, Goodfellow JA, Chavada G, Mallik A, Overell J, Lunn MP, McConnachie A, van Doorn P, Willison HJ.

J Peripher Nerv Syst. 2017 Mar;22(1):4-12. doi: 10.1111/jns.12194.


Immunotherapy for IgM anti-myelin-associated glycoprotein paraprotein-associated peripheral neuropathies.

Lunn MP, Nobile-Orazio E.

Cochrane Database Syst Rev. 2016 Oct 4;10:CD002827. Review.


Diagnosing Dementia in the Clinical Setting: Can Amyloid PET Provide Additional Value Over Cerebrospinal Fluid?

Weston PS, Paterson RW, Dickson J, Barnes A, Bomanji JB, Kayani I, Lunn MP, Mummery CJ, Warren JD, Rossor MN, Fox NC, Zetterberg H, Schott JM.

J Alzheimers Dis. 2016 Oct 18;54(4):1297-1302.


Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome.

Minnema MC, Kimby E, D'Sa S, Fornecker LM, Poulain S, Snijders TJ, Kastritis E, Kremer S, Fitsiori A, Simon L, Davi F, Lunn M, Castillo JJ, Patterson CJ, Le Garff-Tavernier M, Costopoulos M, Leblond V, Kersten MJ, Dimopoulos MA, Treon SP.

Haematologica. 2017 Jan;102(1):43-51. doi: 10.3324/haematol.2016.147728. Epub 2016 Oct 6.


Regarding the past, what is the trial you have always been dreaming of in CIDP?

Hughes RA, Lunn MP.

Rev Neurol (Paris). 2016 Oct;172(10):620-626. doi: 10.1016/j.neurol.2016.07.020. Epub 2016 Sep 13. Review.


Higher frequencies of HLA DQB1*05:01 and anti-glycosphingolipid antibodies in a cluster of severe Guillain-Barré syndrome.

Schirmer L, Worthington V, Solloch U, Loleit V, Grummel V, Lakdawala N, Grant D, Wassmuth R, Schmidt AH, Gebhardt F, Andlauer TF, Sauter J, Berthele A, Lunn MP, Hemmer B.

J Neurol. 2016 Oct;263(10):2105-13. doi: 10.1007/s00415-016-8237-6. Epub 2016 Aug 2.


Do cerebrospinal fluid transfer methods affect measured amyloid β42, total tau, and phosphorylated tau in clinical practice?

Paterson RW, Toombs J, Chapman MD, Nicholas JM, Heslegrave AJ, Slattery CF, Foulkes AJ, Clark CN, Lane CA, Weston PS, Lunn MP, Fox NC, Zetterberg H, Schott JM.

Alzheimers Dement (Amst). 2015 Jul 2;1(3):380-4. doi: 10.1016/j.dadm.2015.06.003. eCollection 2015 Sep.


A unique lineage gives rise to the meibomian gland.

Call M, Fischesser K, Lunn MO, Kao WW.

Mol Vis. 2016 Feb 21;22:168-76. eCollection 2016.


Using florbetapir positron emission tomography to explore cerebrospinal fluid cut points and gray zones in small sample sizes.

Weston PS, Paterson RW, Modat M, Burgos N, Cardoso MJ, Magdalinou N, Lehmann M, Dickson JC, Barnes A, Bomanji JB, Kayani I, Cash DM, Ourselin S, Toombs J, Lunn MP, Mummery CJ, Warren JD, Rossor MN, Fox NC, Zetterberg H, Schott JM.

Alzheimers Dement (Amst). 2015 Nov 2;1(4):440-446. eCollection 2015 Dec.


A proposed dosing algorithm for the individualized dosing of human immunoglobulin in chronic inflammatory neuropathies.

Lunn MP, Ellis L, Hadden RD, Rajabally YA, Winer JB, Reilly MM.

J Peripher Nerv Syst. 2016 Mar;21(1):33-7. doi: 10.1111/jns.12158.


Improving the likelihood of neurology patients being examined using patient feedback.

Appleton JP, Ilinca A, Lindgren A, Puschmann A, Hbahbih M, A Siddiqui K, de Silva R, Jones M, Butterworth R, Willmot M, Hayton T, Lunn M, Nicholl D.

BMJ Qual Improv Rep. 2015 Nov 5;4(1). pii: u209610.w4063. doi: 10.1136/bmjquality.u209610.w4063. eCollection 2015.


Central nervous system involvement by Waldenström macroglobulinaemia (Bing-Neel syndrome): a multi-institutional retrospective study.

Castillo JJ, D'Sa S, Lunn MP, Minnema MC, Tedeschi A, Lansigan F, Palomba ML, Varettoni M, Garcia-Sanz R, Nayak L, Lee EQ, Rinne ML, Norden AD, Ghobrial IM, Treon SP.

Br J Haematol. 2016 Mar;172(5):709-15. doi: 10.1111/bjh.13883. Epub 2015 Dec 21.

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