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Severe bleeding and absent ADP-induced platelet aggregation associated with inherited combined CalDAG-GEFI and P2Y12 deficiencies.

Lunghi B, Lecchi A, Santacroce R, Scavone M, Paniccia R, Artoni A, Gachet C, Castaman G, Margaglione M, Bernardi F, Cattaneo M.

Haematologica. 2019 Oct 24. pii: haematol.2019.232850. doi: 10.3324/haematol.2019.232850. [Epub ahead of print]


C6orf10 Low-Frequency and Rare Variants in Italian Multiple Sclerosis Patients.

Ziliotto N, Marchetti G, Scapoli C, Bovolenta M, Meneghetti S, Benazzo A, Lunghi B, Balestra D, Laino LA, Bozzini N, Guidi I, Salvi F, Straudi S, Gemmati D, Menegatti E, Zamboni P, Bernardi F.

Front Genet. 2019 Jun 26;10:573. doi: 10.3389/fgene.2019.00573. eCollection 2019.


Functional polymorphisms in the LDLR and pharmacokinetics of Factor VIII concentrates.

Lunghi B, Bernardi F, Martinelli N, Frusconi S, Branchini A, Linari S, Marchetti G, Castaman G, Morfini M.

J Thromb Haemost. 2019 Aug;17(8):1288-1296. doi: 10.1111/jth.14473. Epub 2019 May 29.


Performance prediction models based on anthropometric, genetic and psychological traits of Croatian sprinters.

Zaccagni L, Lunghi B, Barbieri D, Rinaldo N, Missoni S, Šaric T, Šarac J, Babic V, Rakovac M, Bernardi F, Gualdi-Russo E.

Biol Sport. 2019 Mar;36(1):17-23. doi: 10.5114/biolsport.2018.78901. Epub 2018 Oct 15.


Apolipoprotein C-III Strongly Correlates with Activated Factor VII-Anti-Thrombin Complex: An Additional Link between Plasma Lipids and Coagulation.

Martinelli N, Baroni M, Castagna A, Lunghi B, Stefanoni F, Tosi F, Croce J, Udali S, Woodhams B, Girelli D, Bernardi F, Olivieri O.

Thromb Haemost. 2019 Feb;119(2):192-202. doi: 10.1055/s-0038-1676817. Epub 2019 Jan 2.


Changes in expression profiles of internal jugular vein wall and plasma protein levels in multiple sclerosis.

Marchetti G, Ziliotto N, Meneghetti S, Baroni M, Lunghi B, Menegatti E, Pedriali M, Salvi F, Bartolomei I, Straudi S, Manfredini F, Voltan R, Basaglia N, Mascoli F, Zamboni P, Bernardi F.

Mol Med. 2018 Aug 9;24(1):42. doi: 10.1186/s10020-018-0043-4.


Severe Reduction in Number and Function of Peripheral T Cells Does Not Afford Protection toward Emphysema and Bronchial Remodeling Induced in Mice by Cigarette Smoke.

De Cunto G, Lunghi B, Bartalesi B, Cavarra E, Fineschi S, Ulivieri C, Lungarella G, Lucattelli M.

Am J Pathol. 2016 Jul;186(7):1814-1824. doi: 10.1016/j.ajpath.2016.03.002. Epub 2016 May 6.


Activated factor VII-antithrombin complex predicts mortality in patients with stable coronary artery disease: a cohort study.

Martinelli N, Girelli D, Baroni M, Guarini P, Sandri M, Lunghi B, Tosi F, Branchini A, Sartori F, Woodhams B, Bernardi F, Olivieri O.

J Thromb Haemost. 2016 Apr;14(4):655-66. doi: 10.1111/jth.13274. Epub 2016 Mar 14.


Smoking p66Shc knocked out mice develop respiratory bronchiolitis with fibrosis but not emphysema.

Lunghi B, De Cunto G, Cavarra E, Fineschi S, Bartalesi B, Lungarella G, Lucattelli M.

PLoS One. 2015 Mar 19;10(3):e0119797. doi: 10.1371/journal.pone.0119797. eCollection 2015.


Factor XI rs2036914 gene polymorphism and occurrence of adverse events after percutaneous coronary intervention. A prospective evaluation.

Campo G, Lunghi B, Pavasini R, Ferraresi P, Punzetti S, Malagù M, Biscaglia S, Ferrari R, Bernardi F.

Int J Cardiol. 2014 Dec 15;177(2):711-3. No abstract available.


An integrated genomic-transcriptomic approach supports a role for the proto-oncogene BCL3 in atherosclerosis.

Marchetti G, Girelli D, Zerbinati C, Lunghi B, Friso S, Meneghetti S, Coen M, Gagliano T, Guastella G, Bochaton-Piallat ML, Pizzolo F, Mascoli F, Malerba G, Bovolenta M, Ferracin M, Olivieri O, Bernardi F, Martinelli N.

Thromb Haemost. 2015 Mar;113(3):655-63. doi: 10.1160/TH14-05-0466. Epub 2014 Nov 6.


The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2.

Renga B, Francisci D, Schiaroli E, Carino A, Cipriani S, D'Amore C, Sidoni A, Sordo RD, Ferri I, Lucattelli M, Lunghi B, Baldelli F, Fiorucci S.

PLoS One. 2014 Apr 15;9(4):e94798. doi: 10.1371/journal.pone.0094798. eCollection 2014.


Molecular basis of coagulation factor V deficiency caused by the R1698W inter-domain mutation.

Calzavarini S, Villoutreix BO, Lunghi B, Livaja R, Bernardi F, Dahlbäck B.

Thromb Haemost. 2013 Jul;110(1):31-8. doi: 10.1160/TH12-10-0780. Epub 2013 Apr 25.


Receptor for advanced glycation end products contributes to postnatal pulmonary development and adult lung maintenance program in mice.

Fineschi S, De Cunto G, Facchinetti F, Civelli M, Imbimbo BP, Carnini C, Villetti G, Lunghi B, Stochino S, Gibbons DL, Hayday A, Lungarella G, Cavarra E.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):164-71. doi: 10.1165/rcmb.2012-0111OC. Epub 2012 Nov 9.


The F11 rs2289252 polymorphism is associated with FXI activity levels and APTT ratio in women with thrombosis.

Lunghi B, Cini M, Legnani C, Bernardi F, Marchetti G.

Thromb Res. 2012 Sep;130(3):563-4. doi: 10.1016/j.thromres.2012.05.004. Epub 2012 May 25. No abstract available.


Functional genetics.

Marchetti G, Pinotti M, Lunghi B, Casari C, Bernardi F.

Thromb Res. 2012 Mar;129(3):336-40. doi: 10.1016/j.thromres.2011.10.028. Epub 2011 Nov 17. Review.


Prospective evaluation of on-clopidogrel platelet reactivity over time in patients treated with percutaneous coronary intervention relationship with gene polymorphisms and clinical outcome.

Campo G, Parrinello G, Ferraresi P, Lunghi B, Tebaldi M, Miccoli M, Marchesini J, Bernardi F, Ferrari R, Valgimigli M.

J Am Coll Cardiol. 2011 Jun 21;57(25):2474-83. doi: 10.1016/j.jacc.2010.12.047.


Novel phenotype and γ-glutamyl carboxylase mutations in combined deficiency of vitamin K-dependent coagulation factors.

Lunghi B, Redaelli R, Caimi TM, Corno AR, Bernardi F, Marchetti G.

Haemophilia. 2011 Sep;17(5):822-4. doi: 10.1111/j.1365-2516.2011.02524.x. Epub 2011 Mar 24. No abstract available.


Polymorphisms at LDLR locus may be associated with coronary artery disease through modulation of coagulation factor VIII activity and independently from lipid profile.

Martinelli N, Girelli D, Lunghi B, Pinotti M, Marchetti G, Malerba G, Pignatti PF, Corrocher R, Olivieri O, Bernardi F.

Blood. 2010 Dec 16;116(25):5688-97. doi: 10.1182/blood-2010-03-277079. Epub 2010 Sep 1.


Absence of proteinase-activated receptor-1 signaling in mice confers protection from fMLP-induced goblet cell metaplasia.

Atzori L, Lucattelli M, Scotton CJ, Laurent GJ, Bartalesi B, De Cunto G, Lunghi B, Chambers RC, Lungarella G.

Am J Respir Cell Mol Biol. 2009 Dec;41(6):680-7. doi: 10.1165/rcmb.2007-0386OC. Epub 2009 Mar 23.


Effect of roflumilast on inflammatory cells in the lungs of cigarette smoke-exposed mice.

Martorana PA, Lunghi B, Lucattelli M, De Cunto G, Beume R, Lungarella G.

BMC Pulm Med. 2008 Aug 28;8:17. doi: 10.1186/1471-2466-8-17.


A new mouse model of Peyronie's disease: an increased expression of hypoxia-inducible factor-1 target genes during the development of penile changes.

Lucattelli M, Lunghi B, Fineschi S, Mirone V, d'Emmanuele di Villa Bianca R, Longo N, Imbimbo C, De Palma R, Sorrentino R, Lungarella G, Cirino G.

Int J Biochem Cell Biol. 2008;40(11):2638-48. doi: 10.1016/j.biocel.2008.05.012. Epub 2008 May 28.


Influence of low-density lipoprotein (LDL) receptor-related protein and ABO blood group genotypes on factor XI levels.

Marchetti G, Lunghi B, Mazzoni G, Cini M, Legnani C, Bernardi F.

Thromb Haemost. 2008 Apr;99(4):789-90. doi: 10.1160/TH07-12-0749. No abstract available.


Vitamin K-induced modification of coagulation phenotype in VKORC1 homozygous deficiency.

Marchetti G, Caruso P, Lunghi B, Pinotti M, Lapecorella M, Napolitano M, Canella A, Mariani G, Bernardi F.

J Thromb Haemost. 2008 May;6(5):797-803. doi: 10.1111/j.1538-7836.2008.02934.x. Epub 2008 Feb 25.


Evaluation of factor V mRNA to define the residual factor V expression levels in severe factor V deficiency.

Lunghi B, Pinotti M, Maestri I, Batorova A, Bernardi F.

Haematologica. 2008 Mar;93(3):477-8. doi: 10.3324/haematol.11952.


Factor V Kuwait alias factor V R3: a rare polymorphism of uncertain functional significance.

Castoldi E, Lunghi B, Rosing J, Bernardi F.

Med Princ Pract. 2007;16(3):244-5; author reply 246. No abstract available.


Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.

Martinelli N, Girelli D, Ferraresi P, Olivieri O, Lunghi B, Manzato F, Corrocher R, Bernardi F.

Blood Coagul Fibrinolysis. 2007 Mar;18(2):125-9.


Contribution of low density lipoprotein receptor-related protein genotypes to coagulation factor VIII levels in thrombotic women.

Marchetti G, Lunghi B, Legnani C, Cini M, Pinotti M, Mascoli F, Bernard F.

Haematologica. 2006 Sep;91(9):1261-3.


Expression of the normal factor V allele modulates the APC resistance phenotype in heterozygous carriers of the factor V Leiden mutation.

Brugge JM, Simioni P, Bernardi F, Tormene D, Lunghi B, Tans G, Pagnan A, Rosing J, Castoldi E.

J Thromb Haemost. 2005 Dec;3(12):2695-702.


Is neutrophil elastase the missing link between emphysema and fibrosis? Evidence from two mouse models.

Lucattelli M, Bartalesi B, Cavarra E, Fineschi S, Lunghi B, Martorana PA, Lungarella G.

Respir Res. 2005 Jul 26;6:83.


The factor V Glu1608Lys mutation is recurrent in familial thrombophilia.

Lunghi B, Scanavini D, Castoldi E, Gemmati D, Tognazzo S, Redaelli R, Ghirarduzzi A, Ieran M, Pinotti M, Bernardi F.

J Thromb Haemost. 2005 Sep;3(9):2032-8. Epub 2005 Jun 24.


An underestimated combination of opposites resulting in enhanced thrombotic tendency.

Simioni P, Castoldi E, Lunghi B, Tormene D, Rosing J, Bernardi F.

Blood. 2005 Oct 1;106(7):2363-5. Epub 2005 Jun 16.


Risks factors for highly unstable response to oral anticoagulation: a case-control study.

Palareti G, Legnani C, Guazzaloca G, Lelia V, Cosmi B, Lunghi B, Marchetti G, Poli D, Pengo V; ad hoc Study Group of the Italian Federation of Anticoagulation Clinics*.

Br J Haematol. 2005 Apr;129(1):72-8.


The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels.

Scanavini D, Legnani C, Lunghi B, Mingozzi F, Palareti G, Bernardi F.

Thromb Haemost. 2005 Mar;93(3):453-6.


Does factor V Asp79His (409 G/C) polymorphism influence factor V and APC resistance levels?

Lunghi B, Scanavini D, Girelli D, Legnani C, Bernardi F.

J Thromb Haemost. 2005 Feb;3(2):415-6. No abstract available.


Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants.

Bartalesi B, Cavarra E, Fineschi S, Lucattelli M, Lunghi B, Martorana PA, Lungarella G.

Eur Respir J. 2005 Jan;25(1):15-22.


Modulation of factor V levels in plasma by polymorphisms in the C2 domain.

Scanavini D, Girelli D, Lunghi B, Martinelli N, Legnani C, Pinotti M, Palareti G, Bernardi F.

Arterioscler Thromb Vasc Biol. 2004 Jan;24(1):200-6. Epub 2003 Dec 1.


Predictive value of D-dimer test for recurrent venous thromboembolism after anticoagulation withdrawal in subjects with a previous idiopathic event and in carriers of congenital thrombophilia.

Palareti G, Legnani C, Cosmi B, Valdré L, Lunghi B, Bernardi F, Coccheri S.

Circulation. 2003 Jul 22;108(3):313-8. Epub 2003 Jul 7.


A FV multiallelic marker detects genetic components of APC resistance contributing to venous thromboembolism in FV Leiden carriers.

Mingozzi F, Legnani C, Lunghi B, Scanavini D, Castoldi E, Palareti G, Marchetti G, Bernardi F.

Thromb Haemost. 2003 Jun;89(6):983-9.


Asymptomatic carriership of factor V Leiden and genotypes of the fibrinogen gene cluster.

Marchetti G, Ferraresi P, Legnani C, Pinotti M, Lunghi B, Scapoli C, Gemmati D, Coccheri S, Palareti G, Bernardi F.

Br J Haematol. 2003 May;121(4):632-8.


Iron overload enhances the development of experimental liver cirrhosis in mice.

Arezzini B, Lunghi B, Lungarella G, Gardi C.

Int J Biochem Cell Biol. 2003 Apr;35(4):486-95.


Venous thromboembolism in young women; role of thrombophilic mutations and oral contraceptive use.

Legnani C, Palareti G, Guazzaloca G, Cosmi B, Lunghi B, Bernardi F, Coccheri S.

Eur Heart J. 2002 Jun;23(12):984-90.


Reduced inhibition of activated prothrombin by heparin and venous thromboembolism: heparin resistance revisited.

Legnani C, Preda L, Palareti G, Lunghi B, Rossi E, Coccheri S.

Haematologica. 2002 Feb;87(2):182-8.


A highly polymorphic microsatellite in the factor V gene is an informative tool for the study of factor V-related disorders.

Castoldi E, Lunghi B, Mingozzi F, Simioni P, Girolami A, Bernardi F.

Br J Haematol. 2001 Sep;114(4):868-70.


Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants.

Cavarra E, Bartalesi B, Lucattelli M, Fineschi S, Lunghi B, Gambelli F, Ortiz LA, Martorana PA, Lungarella G.

Am J Respir Crit Care Med. 2001 Sep 1;164(5):886-90.


A missense mutation (Y1702C) in the coagulation factor V gene is a frequent cause of factor V deficiency in the Italian population.

Castoldi E, Lunghi B, Mingozzi F, Muleo G, Redaelli R, Mariani G, Bernardi F.

Haematologica. 2001 Jun;86(6):629-33.


Combinations of 4 mutations (FV R506Q, FV H1299R, FV Y1702C, PT 20210G/A) affecting the prothrombinase complex in a thrombophilic family.

Castoldi E, Simioni P, Kalafatis M, Lunghi B, Tormene D, Girelli D, Girolami A, Bernardi F.

Blood. 2000 Aug 15;96(4):1443-8.


Mutations in the R2 FV gene affect the ratio between the two FV isoforms in plasma.

Castoldi E, Rosing J, Girelli D, Hoekema L, Lunghi B, Mingozzi F, Ferraresi P, Friso S, Corrocher R, Tans G, Bernardi F.

Thromb Haemost. 2000 Mar;83(3):362-5.


Phenotype and genotype expression in pseudohomozygous factor VLEIDEN : the need for phenotype analysis.

Kalafatis M, Bernardi F, Simioni P, Lunghi B, Girolami A, Mann KG.

Arterioscler Thromb Vasc Biol. 1999 Feb;19(2):336-42.


Molecular bases of pseudo-homozygous APC resistance: the compound heterozygosity for FV R506Q and a FV null mutation results in the exclusive presence of FV Leiden molecules in plasma.

Castoldi E, Kalafatis M, Lunghi B, Simioni P, Ioannou PA, Petio M, Girolami A, Mann KG, Bernardi F.

Thromb Haemost. 1998 Sep;80(3):403-6.


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