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Items: 33

1.

EXOSC4 functions as a potential oncogene in development and progression of colorectal cancer.

Pan Y, Tong JHM, Kang W, Lung RWM, Chak WP, Chung LY, Wu F, Li H, Yu J, Chan AWH, To KF.

Mol Carcinog. 2018 Aug 29. doi: 10.1002/mc.22896. [Epub ahead of print]

PMID:
30155936
2.

RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.

Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF.

Mol Cancer. 2018 Jul 23;17(1):102. doi: 10.1186/s12943-018-0853-6.

3.

Activation of sterol regulatory element-binding protein 1 (SREBP1)-mediated lipogenesis by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) promotes cell proliferation and progression of nasopharyngeal carcinoma.

Lo AK, Lung RW, Dawson CW, Young LS, Ko CW, Yeung WW, Kang W, To KF, Lo KW.

J Pathol. 2018 Oct;246(2):180-190. doi: 10.1002/path.5130. Epub 2018 Aug 22.

PMID:
29968360
4.

Granulin epithelin precursor promotes colorectal carcinogenesis by activating MARK/ERK pathway.

Pan Y, Cheung ST, Tong JHM, Tin KY, Kang W, Lung RWM, Wu F, Li H, Ng SSM, Mak TWC, To KF, Chan AWH.

J Transl Med. 2018 Jun 4;16(1):150. doi: 10.1186/s12967-018-1530-7.

5.

Assessment of programmed cell death ligand-1 expression by 4 diagnostic assays and its clinicopathological correlation in a large cohort of surgical resected non-small cell lung carcinoma.

Chan AWH, Tong JHM, Kwan JSH, Chow C, Chung LY, Chau SL, Lung RWM, Ng CSH, Wan IYP, Mok TSK, To KF.

Mod Pathol. 2018 Sep;31(9):1381-1390. doi: 10.1038/s41379-018-0053-3. Epub 2018 Apr 30.

PMID:
29713040
6.

miR-375 is involved in Hippo pathway by targeting YAP1/TEAD4-CTGF axis in gastric carcinogenesis.

Kang W, Huang T, Zhou Y, Zhang J, Lung RWM, Tong JHM, Chan AWH, Zhang B, Wong CC, Wu F, Dong Y, Wang S, Yang W, Pan Y, Chak WP, Cheung AHK, Pang JCS, Yu J, Cheng ASL, To KF.

Cell Death Dis. 2018 Jan 24;9(2):92. doi: 10.1038/s41419-017-0134-0.

7.

EBV-encoded miRNAs target ATM-mediated response in nasopharyngeal carcinoma.

Lung RW, Hau PM, Yu KH, Yip KY, Tong JH, Chak WP, Chan AW, Lam KH, Lo AK, Tin EK, Chau SL, Pang JC, Kwan JS, Busson P, Young LS, Yap LF, Tsao SW, To KF, Lo KW.

J Pathol. 2018 Apr;244(4):394-407. doi: 10.1002/path.5018. Epub 2018 Feb 16.

8.

Downregulation of long non-coding RNA MEG3 in nasopharyngeal carcinoma.

Chak WP, Lung RW, Tong JH, Chan SY, Lun SW, Tsao SW, Lo KW, To KF.

Mol Carcinog. 2017 Mar;56(3):1041-1054. doi: 10.1002/mc.22569. Epub 2016 Oct 20.

PMID:
27597634
9.

MET Amplification and Exon 14 Splice Site Mutation Define Unique Molecular Subgroups of Non-Small Cell Lung Carcinoma with Poor Prognosis.

Tong JH, Yeung SF, Chan AW, Chung LY, Chau SL, Lung RW, Tong CY, Chow C, Tin EK, Yu YH, Li H, Pan Y, Chak WP, Ng CS, Mok TS, To KF.

Clin Cancer Res. 2016 Jun 15;22(12):3048-56. doi: 10.1158/1078-0432.CCR-15-2061. Epub 2016 Feb 4.

10.

Profiling of Oncogenic Driver Events in Lung Adenocarcinoma Revealed MET Mutation as Independent Prognostic Factor.

Yeung SF, Tong JHM, Law PPW, Chung LY, Lung RWM, Tong CYK, Chow C, Chan AWH, Wan IYP, Mok TSK, To KF.

J Thorac Oncol. 2015 Sep;10(9):1292-1300. doi: 10.1097/JTO.0000000000000620.

11.

Targeting of YAP1 by microRNA-15a and microRNA-16-1 exerts tumor suppressor function in gastric adenocarcinoma.

Kang W, Tong JH, Lung RW, Dong Y, Zhao J, Liang Q, Zhang L, Pan Y, Yang W, Pang JC, Cheng AS, Yu J, To KF.

Mol Cancer. 2015 Feb 22;14:52. doi: 10.1186/s12943-015-0323-3.

12.

let-7b/g silencing activates AKT signaling to promote gastric carcinogenesis.

Kang W, Tong JH, Lung RW, Dong Y, Yang W, Pan Y, Lau KM, Yu J, Cheng AS, To KF.

J Transl Med. 2014 Oct 5;12:281. doi: 10.1186/s12967-014-0281-3.

13.

Integrative identification of Epstein-Barr virus-associated mutations and epigenetic alterations in gastric cancer.

Liang Q, Yao X, Tang S, Zhang J, Yau TO, Li X, Tang CM, Kang W, Lung RW, Li JW, Chan TF, Xing R, Lu Y, Lo KW, Wong N, To KF, Yu C, Chan FK, Sung JJ, Yu J.

Gastroenterology. 2014 Dec;147(6):1350-62.e4. doi: 10.1053/j.gastro.2014.08.036. Epub 2014 Aug 28.

14.

Characterization of rare transforming KRAS mutations in sporadic colorectal cancer.

Tong JH, Lung RW, Sin FM, Law PP, Kang W, Chan AW, Ma BB, Mak TW, Ng SS, To KF.

Cancer Biol Ther. 2014 Jun 1;15(6):768-76. doi: 10.4161/cbt.28550. Epub 2014 Mar 18.

15.

Viral-human chimeric transcript predisposes risk to liver cancer development and progression.

Lau CC, Sun T, Ching AK, He M, Li JW, Wong AM, Co NN, Chan AW, Li PS, Lung RW, Tong JH, Lai PB, Chan HL, To KF, Chan TF, Wong N.

Cancer Cell. 2014 Mar 17;25(3):335-49. doi: 10.1016/j.ccr.2014.01.030. Epub 2014 Feb 27.

16.

Emerging roles of small Epstein-Barr virus derived non-coding RNAs in epithelial malignancy.

Lung RW, Tong JH, To KF.

Int J Mol Sci. 2013 Aug 23;14(9):17378-409. doi: 10.3390/ijms140917378. Review.

17.

Identification of a recurrent transforming UBR5-ZNF423 fusion gene in EBV-associated nasopharyngeal carcinoma.

Chung GT, Lung RW, Hui AB, Yip KY, Woo JK, Chow C, Tong CY, Lee SD, Yuen JW, Lun SW, Tso KK, Wong N, Tsao SW, Yip TT, Busson P, Kim H, Seo JS, O'Sullivan B, Liu FF, To KF, Lo KW.

J Pathol. 2013 Oct;231(2):158-67. doi: 10.1002/path.4240.

18.

Somatostatin receptor 1, a novel EBV-associated CpG hypermethylated gene, contributes to the pathogenesis of EBV-associated gastric cancer.

Zhao J, Liang Q, Cheung KF, Kang W, Dong Y, Lung RW, Tong JH, To KF, Sung JJ, Yu J.

Br J Cancer. 2013 Jun 25;108(12):2557-64. doi: 10.1038/bjc.2013.263. Epub 2013 May 30.

19.

Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant.

To KF, Tong JH, Yeung KS, Lung RW, Law PP, Chau SL, Kang W, Tong CY, Chow C, Chan AW, Leung LK, Mok TS.

J Thorac Oncol. 2013 Jul;8(7):883-91. doi: 10.1097/JTO.0b013e3182904e22.

20.

Deep sequencing of small RNA transcriptome reveals novel non-coding RNAs in hepatocellular carcinoma.

Law PT, Qin H, Ching AK, Lai KP, Co NN, He M, Lung RW, Chan AW, Chan TF, Wong N.

J Hepatol. 2013 Jun;58(6):1165-73. doi: 10.1016/j.jhep.2013.01.032. Epub 2013 Jan 29.

PMID:
23376363
21.

Genome-wide identification of Epstein-Barr virus-driven promoter methylation profiles of human genes in gastric cancer cells.

Zhao J, Liang Q, Cheung KF, Kang W, Lung RW, Tong JH, To KF, Sung JJ, Yu J.

Cancer. 2013 Jan 15;119(2):304-12. doi: 10.1002/cncr.27724. Epub 2012 Jul 25.

22.

A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma.

Lung RW, Wang X, Tong JH, Chau SL, Lau KM, Cheng SH, Woo JK, Woo J, Leung PC, Ng MH, Tang NL, To KF.

Mol Carcinog. 2013 Nov;52 Suppl 1:E28-38. doi: 10.1002/mc.21937. Epub 2012 Jun 18.

PMID:
22711332
23.

Stathmin1 plays oncogenic role and is a target of microRNA-223 in gastric cancer.

Kang W, Tong JH, Chan AW, Lung RW, Chau SL, Wong QW, Wong N, Yu J, Cheng AS, To KF.

PLoS One. 2012;7(3):e33919. doi: 10.1371/journal.pone.0033919. Epub 2012 Mar 28.

24.

Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.

Yip WK, Cheng AS, Zhu R, Lung RW, Tsang DP, Lau SS, Chen Y, Sung JG, Lai PB, Ng EK, Yu J, Wong N, To KF, Wong VW, Sung JJ, Chan HL.

PLoS One. 2011;6(8):e22888. doi: 10.1371/journal.pone.0022888. Epub 2011 Aug 4.

25.

Yes-associated protein 1 exhibits oncogenic property in gastric cancer and its nuclear accumulation associates with poor prognosis.

Kang W, Tong JH, Chan AW, Lee TL, Lung RW, Leung PP, So KK, Wu K, Fan D, Yu J, Sung JJ, To KF.

Clin Cancer Res. 2011 Apr 15;17(8):2130-9. doi: 10.1158/1078-0432.CCR-10-2467. Epub 2011 Feb 23.

26.

Sequencing analysis of the 3' region of the cagA gene in Helicobacter pylori isolated from Hong Kong Chinese patients.

To KF, Leung WK, Ng KW, Tong JH, Lung RW.

Hong Kong Med J. 2010;16(5 Suppl 4):8-12. No abstract available.

27.

Putative tumour-suppressor gene DAB2 is frequently down regulated by promoter hypermethylation in nasopharyngeal carcinoma.

Tong JH, Ng DC, Chau SL, So KK, Leung PP, Lee TL, Lung RW, Chan MW, Chan AW, Lo KW, To KF.

BMC Cancer. 2010 Jun 3;10:253. doi: 10.1186/1471-2407-10-253.

28.

Modulation of LMP2A expression by a newly identified Epstein-Barr virus-encoded microRNA miR-BART22.

Lung RW, Tong JH, Sung YM, Leung PS, Ng DC, Chau SL, Chan AW, Ng EK, Lo KW, To KF.

Neoplasia. 2009 Nov;11(11):1174-84.

29.

An Epstein-Barr virus-encoded microRNA targets PUMA to promote host cell survival.

Choy EY, Siu KL, Kok KH, Lung RW, Tsang CM, To KF, Kwong DL, Tsao SW, Jin DY.

J Exp Med. 2008 Oct 27;205(11):2551-60. doi: 10.1084/jem.20072581. Epub 2008 Oct 6.

30.

MicroRNA-223 is commonly repressed in hepatocellular carcinoma and potentiates expression of Stathmin1.

Wong QW, Lung RW, Law PT, Lai PB, Chan KY, To KF, Wong N.

Gastroenterology. 2008 Jul;135(1):257-69. doi: 10.1053/j.gastro.2008.04.003. Epub 2008 Apr 11.

PMID:
18555017
31.

Modulation of LMP1 protein expression by EBV-encoded microRNAs.

Lo AK, To KF, Lo KW, Lung RW, Hui JW, Liao G, Hayward SD.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16164-9. Epub 2007 Oct 2.

32.

Expression of viral capsid protein antigen against Epstein-Barr virus in plastids of Nicotiana tabacum cv. SR1.

Lee MY, Zhou Y, Lung RW, Chye ML, Yip WK, Zee SY, Lam E.

Biotechnol Bioeng. 2006 Aug 20;94(6):1129-37.

PMID:
16586511

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