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Items: 1 to 50 of 275

1.

Biomarker-assisted identification of sepsis-related acute liver impairment: a frequent and deadly condition in critically ill patients.

Jensen JS, Peters L, Itenov TS, Bestle M, Thormar KM, Mohr TT, Lundgren B, Grarup J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group.

Clin Chem Lab Med. 2019 Aug 27;57(9):1422-1431. doi: 10.1515/cclm-2018-1350.

PMID:
30951497
2.

SfnR2 Regulates Dimethyl Sulfide-Related Utilization in Pseudomonas aeruginosa PAO1.

Lundgren BR, Sarwar Z, Feldman KS, Shoytush JM, Nomura CT.

J Bacteriol. 2019 Jan 28;201(4). pii: e00606-18. doi: 10.1128/JB.00606-18. Print 2019 Feb 15.

3.

Using a New Photo Scale to Compare Product Integration of Different Hyaluronan-Based Fillers After Injection in Human Ex Vivo Skin.

Lundgren B, Sandkvist U, Bordier N, Gauthier B.

J Drugs Dermatol. 2018 Sep 1;17(9):982-986.

PMID:
30235386
4.

Degradation of Hylauronic Acid Fillers Using Hyaluronidase in an In Vivo Model.

Ferraz RM, Sandkvist U, Lundgren B.

J Drugs Dermatol. 2018 May 1;17(5):548-553.

PMID:
29742187
5.

Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.

Pettersson-Klein AT, Izadi M, Ferreira DMS, Cervenka I, Correia JC, Martinez-Redondo V, Southern M, Cameron M, Kamenecka T, Agudelo LZ, Porsmyr-Palmertz M, Martens U, Lundgren B, Otrocka M, Jenmalm-Jensen A, Griffin PR, Ruas JL.

Mol Metab. 2018 Mar;9:28-42. doi: 10.1016/j.molmet.2018.01.017. Epub 2018 Feb 3.

6.

Defining Information Security.

Lundgren B, Möller N.

Sci Eng Ethics. 2019 Apr;25(2):419-441. doi: 10.1007/s11948-017-9992-1. Epub 2017 Nov 15.

7.

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.

Carreras-Puigvert J, Zitnik M, Jemth AS, Carter M, Unterlass JE, Hallström B, Loseva O, Karem Z, Calderón-Montaño JM, Lindskog C, Edqvist PH, Matuszewski DJ, Ait Blal H, Berntsson RPA, Häggblad M, Martens U, Studham M, Lundgren B, Wählby C, Sonnhammer ELL, Lundberg E, Stenmark P, Zupan B, Helleday T.

Nat Commun. 2017 Nov 16;8(1):1541. doi: 10.1038/s41467-017-01642-w.

8.

Targeting the alternative sigma factor RpoN to combat virulence in Pseudomonas aeruginosa.

Lloyd MG, Lundgren BR, Hall CW, Gagnon LB, Mah TF, Moffat JF, Nomura CT.

Sci Rep. 2017 Oct 3;7(1):12615. doi: 10.1038/s41598-017-12667-y.

9.

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.

Llona-Minguez S, Häggblad M, Martens U, Throup A, Loseva O, Jemth AS, Lundgren B, Scobie M, Helleday T.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3897-3904. doi: 10.1016/j.bmcl.2017.06.038. Epub 2017 Jun 16.

PMID:
28687206
10.

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.

Llona-Minguez S, Häggblad M, Martens U, Johansson L, Sigmundsson K, Lundbäck T, Loseva O, Jemth AS, Lundgren B, Jensen AJ, Scobie M, Helleday T.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3219-3225. doi: 10.1016/j.bmcl.2017.06.039. Epub 2017 Jun 15.

PMID:
28655422
11.

Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.

Gad H, Koolmeister T, Jemth AS, Eshtad S, Jacques SA, Ström CE, Svensson LM, Schultz N, Lundbäck T, Einarsdottir BO, Saleh A, Göktürk C, Baranczewski P, Svensson R, Berntsson RP, Gustafsson R, Strömberg K, Sanjiv K, Jacques-Cordonnier MC, Desroses M, Gustavsson AL, Olofsson R, Johansson F, Homan EJ, Loseva O, Bräutigam L, Johansson L, Höglund A, Hagenkort A, Pham T, Altun M, Gaugaz FZ, Vikingsson S, Evers B, Henriksson M, Vallin KSA, Wallner OA, Hammarström LGJ, Wiita E, Almlöf I, Kalderén C, Axelsson H, Djureinovic T, Carreras Puigvert J, Häggblad M, Jeppsson F, Martens U, Lundin C, Lundgren B, Granelli I, Jenmalm Jensen A, Artursson P, Nilsson JA, Stenmark P, Scobie M; Ulrika Warpman Berglund &Thomas Helleday.

Nature. 2017 Apr 26;544(7651):508. doi: 10.1038/nature22083. No abstract available.

PMID:
28447629
12.

DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.

Lundgren BR, Bailey FJ, Moley G, Nomura CT.

J Bacteriol. 2017 Mar 28;199(8). pii: e00001-17. doi: 10.1128/JB.00001-17. Print 2017 Apr 15.

13.

Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.

Llona-Minguez S, Höglund A, Wiita E, Almlöf I, Mateus A, Calderón-Montaño JM, Cazares-Körner C, Homan E, Loseva O, Baranczewski P, Jemth AS, Häggblad M, Martens U, Lundgren B, Artursson P, Lundbäck T, Jenmalm Jensen A, Warpman Berglund U, Scobie M, Helleday T.

J Med Chem. 2017 Mar 9;60(5):2148-2154. doi: 10.1021/acs.jmedchem.6b01786. Epub 2017 Feb 15.

PMID:
28145708
14.

Mistake is to Myth What Pretense is to Fiction: A Reply to Goodman.

Lundgren B.

Philosophia (Ramat Gan). 2017;45(3):1275-1282. doi: 10.1007/s11406-017-9812-5. Epub 2017 Mar 8.

15.

Enhancing poly(3-hydroxyalkanoate) production in Escherichia coli by the removal of the regulatory gene arcA.

Scheel RA, Ji L, Lundgren BR, Nomura CT.

AMB Express. 2016 Dec;6(1):120. doi: 10.1186/s13568-016-0291-z. Epub 2016 Nov 23.

16.

Prediction of non-recovery from ventilator-demanding acute respiratory failure, ARDS and death using lung damage biomarkers: data from a 1200-patient critical care randomized trial.

Jensen JS, Itenov TS, Thormar KM, Hein L, Mohr TT, Andersen MH, Løken J, Tousi H, Lundgren B, Boesen HC, Johansen ME, Ostrowski SR, Johansson PI, Grarup J, Vestbo J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group.

Ann Intensive Care. 2016 Dec;6(1):114. doi: 10.1186/s13613-016-0212-y. Epub 2016 Nov 21.

17.

Case-specific potentiation of glioblastoma drugs by pterostilbene.

Schmidt L, Baskaran S, Johansson P, Padhan N, Matuszewski D, Green LC, Elfineh L, Wee S, Häggblad M, Martens U, Westermark B, Forsberg-Nilsson K, Uhrbom L, Claesson-Welsh L, Andäng M, Sintorn IM, Lundgren B, Lönnstedt I, Krona C, Nelander S.

Oncotarget. 2016 Nov 8;7(45):73200-73215. doi: 10.18632/oncotarget.12298.

18.

Cloning and heterologous expression of a novel subgroup of class IV polyhydroxyalkanoate synthase genes from the genus Bacillus.

Mizuno K, Kihara T, Tsuge T, Lundgren BR, Sarwar Z, Pinto A, Nomura CT.

Biosci Biotechnol Biochem. 2017 Jan;81(1):194-196. Epub 2016 Sep 9.

PMID:
27609142
19.

A rapid and efficient electroporation method for transformation of Halomonas sp. O-1.

Harris JR, Lundgren BR, Grzeskowiak BR, Mizuno K, Nomura CT.

J Microbiol Methods. 2016 Oct;129:127-132. doi: 10.1016/j.mimet.2016.08.009. Epub 2016 Aug 16.

PMID:
27542998
20.

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue.

Hassan MI, Lundgren BR, Chaumun M, Whitfield DM, Clark B, Schoenhofen IC, Boddy CN.

Angew Chem Int Ed Engl. 2016 Sep 19;55(39):12018-21. doi: 10.1002/anie.201606006. Epub 2016 Aug 19.

PMID:
27538580
21.

Erratum for Sarwar et al., GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1.

Sarwar Z, Lundgren BR, Grassa MT, Wang MX, Gribble M, Moffat JF, Nomura CT.

mSphere. 2016 Jul 27;1(4). pii: e00200-16. doi: 10.1128/mSphere.00200-16. eCollection 2016 Jul-Aug.

22.

Ethanolamine Catabolism in Pseudomonas aeruginosa PAO1 Is Regulated by the Enhancer-Binding Protein EatR (PA4021) and the Alternative Sigma Factor RpoN.

Lundgren BR, Sarwar Z, Pinto A, Ganley JG, Nomura CT.

J Bacteriol. 2016 Aug 11;198(17):2318-29. doi: 10.1128/JB.00357-16. Print 2016 Sep 1.

23.

GcsR, a TyrR-Like Enhancer-Binding Protein, Regulates Expression of the Glycine Cleavage System in Pseudomonas aeruginosa PAO1.

Sarwar Z, Lundgren BR, Grassa MT, Wang MX, Gribble M, Moffat JF, Nomura CT.

mSphere. 2016 Apr 27;1(2). pii: e00020-16. doi: 10.1128/mSphere.00020-16. eCollection 2016 Mar-Apr. Erratum in: mSphere. 2016 Jul-Aug;1(4). pii: e00200-16. doi: 10.1128/mSphere.00200-16.

24.

Framing post-pandemic preparedness: Comparing eight European plans.

Holmberg M, Lundgren B.

Glob Public Health. 2018 Jan;13(1):99-114. doi: 10.1080/17441692.2016.1149202. Epub 2016 Mar 7.

PMID:
26948258
25.

Correction: Localisation of Nursery Areas Based on Comparative Analyses of the Horizontal and Vertical Distribution Patterns of Juvenile Baltic Cod (Gadus morhua).

Nielsen JR, Lundgren B, Kristensen K, Bastardie F.

PLoS One. 2016 Feb 3;11(2):e0148721. doi: 10.1371/journal.pone.0148721. eCollection 2016. No abstract available.

26.

Defining the Metabolic Functions and Roles in Virulence of the rpoN1 and rpoN2 Genes in Ralstonia solanacearum GMI1000.

Lundgren BR, Connolly MP, Choudhary P, Brookins-Little TS, Chatterjee S, Raina R, Nomura CT.

PLoS One. 2015 Dec 11;10(12):e0144852. doi: 10.1371/journal.pone.0144852. eCollection 2015.

27.

The metabolism of (R)-3-hydroxybutyrate is regulated by the enhancer-binding protein PA2005 and the alternative sigma factor RpoN in Pseudomonas aeruginosa PAO1.

Lundgren BR, Harris JR, Sarwar Z, Scheel RA, Nomura CT.

Microbiology. 2015 Nov;161(Pt 11):2232-42. doi: 10.1099/mic.0.000163. Epub 2015 Aug 25.

28.
29.

Profound endothelial damage predicts impending organ failure and death in sepsis.

Johansen ME, Johansson PI, Ostrowski SR, Bestle MH, Hein L, Jensen AL, Søe-Jensen P, Andersen MH, Steensen M, Mohr T, Thormar K, Lundgren B, Cozzi-Lepri A, Lundgren JD, Jensen JU.

Semin Thromb Hemost. 2015 Feb;41(1):16-25. doi: 10.1055/s-0034-1398377. Epub 2015 Jan 15.

PMID:
25590523
30.

Invasive Candida infections and the harm from antibacterial drugs in critically ill patients: data from a randomized, controlled trial to determine the role of ciprofloxacin, piperacillin-tazobactam, meropenem, and cefuroxime.

Jensen JU, Hein L, Lundgren B, Bestle MH, Mohr T, Andersen MH, Løken J, Tousi H, Søe-Jensen P, Lauritsen AØ, Strange D, Petersen JA, Thormar K, Larsen KM, Drenck NE, Helweg-Larsen J, Johansen ME, Reinholdt K, Møller JK, Olesen B, Arendrup MC, Østergaard C, Cozzi-Lepri A, Grarup J, Lundgren JD; Procalcitonin and Survival Study Group.

Crit Care Med. 2015 Mar;43(3):594-602. doi: 10.1097/CCM.0000000000000746.

PMID:
25493970
31.

Deletion of the pflA gene in Escherichia coli LS5218 and its effects on the production of polyhydroxyalkanoates using beechwood xylan as a feedstock.

Salamanca-Cardona L, Scheel RA, Lundgren BR, Stipanovic AJ, Matsumoto K, Taguchi S, Nomura CT.

Bioengineered. 2014 Sep-Oct;5(5):284-7. doi: 10.4161/bioe.29595.

32.

Narrating narcolepsy--centering a side effect.

Lundgren B.

Med Anthropol. 2015;34(2):150-65. doi: 10.1080/01459740.2014.962694.

PMID:
25457625
33.

Genetic analysis of the assimilation of C5-dicarboxylic acids in Pseudomonas aeruginosa PAO1.

Lundgren BR, Villegas-Peñaranda LR, Harris JR, Mottern AM, Dunn DM, Boddy CN, Nomura CT.

J Bacteriol. 2014 Jul;196(14):2543-51. doi: 10.1128/JB.01615-14. Epub 2014 May 2.

34.

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.

Gad H, Koolmeister T, Jemth AS, Eshtad S, Jacques SA, Ström CE, Svensson LM, Schultz N, Lundbäck T, Einarsdottir BO, Saleh A, Göktürk C, Baranczewski P, Svensson R, Berntsson RP, Gustafsson R, Strömberg K, Sanjiv K, Jacques-Cordonnier MC, Desroses M, Gustavsson AL, Olofsson R, Johansson F, Homan EJ, Loseva O, Bräutigam L, Johansson L, Höglund A, Hagenkort A, Pham T, Altun M, Gaugaz FZ, Vikingsson S, Evers B, Henriksson M, Vallin KS, Wallner OA, Hammarström LG, Wiita E, Almlöf I, Kalderén C, Axelsson H, Djureinovic T, Puigvert JC, Häggblad M, Jeppsson F, Martens U, Lundin C, Lundgren B, Granelli I, Jensen AJ, Artursson P, Nilsson JA, Stenmark P, Scobie M, Berglund UW, Helleday T.

Nature. 2014 Apr 10;508(7495):215-21. doi: 10.1038/nature13181. Epub 2014 Apr 2. Erratum in: Nature. 2017 Apr 26;544(7651):508.

PMID:
24695224
35.

Outbreak of wound botulism in people who inject drugs, Norway, October to November 2013.

MacDonald E, Arnesen TM, Brantsaeter AB, Gerlyng P, Grepp M, Hansen BÅ, Jonsrud K, Lundgren B, Mellegård H, Møller-Stray J, Rønning K, Vestrheim DF, Vold L.

Euro Surveill. 2013 Nov 7;18(45):20630.

36.

Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.

Schmidt L, Kling T, Monsefi N, Olsson M, Hansson C, Baskaran S, Lundgren B, Martens U, Häggblad M, Westermark B, Forsberg Nilsson K, Uhrbom L, Karlsson-Lindahl L, Gerlee P, Nelander S.

Neuro Oncol. 2013 Nov;15(11):1469-78. doi: 10.1093/neuonc/not111. Epub 2013 Oct 6.

37.

Localisation of nursery areas based on comparative analyses of the horizontal and vertical distribution patterns of juvenile Baltic cod (Gadus morhua).

Nielsen JR, Lundgren B, Kristensen K, Bastardie F.

PLoS One. 2013 Aug 14;8(8):e70668. doi: 10.1371/journal.pone.0070668. eCollection 2013. Erratum in: PLoS One. 2016;11(2):e0148721.

38.

Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.

Johansson HJ, Sanchez BC, Mundt F, Forshed J, Kovacs A, Panizza E, Hultin-Rosenberg L, Lundgren B, Martens U, Máthé G, Yakhini Z, Helou K, Krawiec K, Kanter L, Hjerpe A, Stål O, Linderholm BK, Lehtiö J.

Nat Commun. 2013;4:2175. doi: 10.1038/ncomms3175.

39.

Gene PA2449 is essential for glycine metabolism and pyocyanin biosynthesis in Pseudomonas aeruginosa PAO1.

Lundgren BR, Thornton W, Dornan MH, Villegas-Peñaranda LR, Boddy CN, Nomura CT.

J Bacteriol. 2013 May;195(9):2087-100. doi: 10.1128/JB.02205-12. Epub 2013 Mar 1.

40.

Thymic deletion and regulatory T cells prevent antimyeloperoxidase GN.

Tan DS, Gan PY, O'Sullivan KM, Hammett MV, Summers SA, Ooi JD, Lundgren BA, Boyd RL, Scott HS, Kitching AR, Chidgey AP, Holdsworth SR.

J Am Soc Nephrol. 2013 Mar;24(4):573-85. doi: 10.1681/ASN.2012090898. Epub 2013 Feb 7.

41.

An abbreviated MLVA identifies Escherichia coli ST131 as the major extended-spectrum β-lactamase-producing lineage in the Copenhagen area.

Nielsen JB, Albayati A, Jørgensen RL, Hansen KH, Lundgren B, Schønning K.

Eur J Clin Microbiol Infect Dis. 2013 Mar;32(3):431-6. doi: 10.1007/s10096-012-1764-x. Epub 2012 Nov 6.

PMID:
23129461
42.

Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE.

Isaksson M, Lundgren BA, Ahlgren KM, Kämpe O, Lobell A.

Eur J Immunol. 2012 Oct;42(10):2555-63. doi: 10.1002/eji.201142239. Epub 2012 Aug 8.

43.

Escherichia coli clonal group A causing bacteraemia of urinary tract origin.

Skjøt-Rasmussen L, Olsen SS, Jakobsen L, Ejrnaes K, Scheutz F, Lundgren B, Frimodt-Møller N, Hammerum AM.

Clin Microbiol Infect. 2013 Jul;19(7):656-61. doi: 10.1111/j.1469-0691.2012.03961.x. Epub 2012 Jul 12.

44.

Shadow effects in simulated ultrasound images derived from computed tomography images using a focused beam tracing model.

Pham AH, Lundgren B, Stage B, Møller Pedersen M, Bachmann Nielsen M, Hemmsen MC, Arendt Jensen J.

J Acoust Soc Am. 2012 Jul;132(1):487-97. doi: 10.1121/1.4726031.

PMID:
22779495
45.

Virulence factors and phylogenetic grouping of Escherichia coli isolates from patients with bacteraemia of urinary tract origin relate to sex and hospital- vs. community-acquired origin.

Skjøt-Rasmussen L, Ejrnæs K, Lundgren B, Hammerum AM, Frimodt-Møller N.

Int J Med Microbiol. 2012 Jul;302(3):129-34. doi: 10.1016/j.ijmm.2012.03.002. Epub 2012 May 8.

PMID:
22571989
46.

Kidney failure related to broad-spectrum antibiotics in critically ill patients: secondary end point results from a 1200 patient randomised trial.

Jensen JU, Hein L, Lundgren B, Bestle MH, Mohr T, Andersen MH, Thornberg KJ, Løken J, Steensen M, Fox Z, Tousi H, Søe-Jensen P, Lauritsen AØ, Strange DG, Reiter N, Thormar K, Fjeldborg PC, Larsen KM, Drenck NE, Johansen ME, Nielsen LR, Ostergaard C, Kjær J, Grarup J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group.

BMJ Open. 2012 Mar 11;2(2):e000635. doi: 10.1136/bmjopen-2011-000635. Print 2012.

47.

Characteristics of Escherichia coli causing persistence or relapse of urinary tract infections: phylogenetic groups, virulence factors and biofilm formation.

Ejrnæs K, Stegger M, Reisner A, Ferry S, Monsen T, Holm SE, Lundgren B, Frimodt-Møller N.

Virulence. 2011 Nov-Dec;2(6):528-37. doi: 10.4161/viru.2.6.18189. Epub 2011 Nov 1.

PMID:
22030858
48.

CBG Santiago: a novel CBG mutation.

Torpy DJ, Lundgren BA, Ho JT, Lewis JG, Scott HS, Mericq V.

J Clin Endocrinol Metab. 2012 Jan;97(1):E151-5. doi: 10.1210/jc.2011-2022. Epub 2011 Oct 19.

PMID:
22013108
49.

Autoimmune regulator (AIRE)-deficient CD8+CD28low regulatory T lymphocytes fail to control experimental colitis.

Pomié C, Vicente R, Vuddamalay Y, Lundgren BA, van der Hoek M, Enault G, Kagan J, Fazilleau N, Scott HS, Romagnoli P, van Meerwijk JP.

Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12437-42. doi: 10.1073/pnas.1107136108. Epub 2011 Jul 11.

50.

Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: a randomized trial.

Jensen JU, Hein L, Lundgren B, Bestle MH, Mohr TT, Andersen MH, Thornberg KJ, Løken J, Steensen M, Fox Z, Tousi H, Søe-Jensen P, Lauritsen AØ, Strange D, Petersen PL, Reiter N, Hestad S, Thormar K, Fjeldborg P, Larsen KM, Drenck NE, Ostergaard C, Kjær J, Grarup J, Lundgren JD; Procalcitonin And Survival Study (PASS) Group.

Crit Care Med. 2011 Sep;39(9):2048-58. doi: 10.1097/CCM.0b013e31821e8791.

PMID:
21572328

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