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Items: 1 to 50 of 68

1.

The impact of SGLT2 inhibitors, compared with insulin, on diabetic bone disease in a mouse model of type 1 diabetes.

Thrailkill KM, Nyman JS, Bunn RC, Uppuganti S, Thompson KL, Lumpkin CK Jr, Kalaitzoglou E, Fowlkes JL.

Bone. 2017 Jan;94:141-151. doi: 10.1016/j.bone.2016.10.026. Epub 2016 Oct 28.

2.

Corrigendum to "SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice" [Bone 82 (2016) 101-107].

Thrailkill KM, Bunn RC, Nyman JS, Rettiganti MR, Cockrell GE, Wahl EC, Uppuganti S, Lumpkin CK Jr, Fowlkes JL.

Bone. 2017 Dec;105:316. doi: 10.1016/j.bone.2016.11.021. Epub 2016 Nov 29. No abstract available.

PMID:
27913134
3.

Nutlin-3 treatment spares cisplatin-induced inhibition of bone healing while maintaining osteosarcoma toxicity.

Stine KC, Wahl EC, Liu L, Skinner RA, VanderSchilden J, Bunn RC, Montgomery CO, Aronson J, Becton DL, Nicholas RW, Swearingen CJ, Suva LJ, Lumpkin CK.

J Orthop Res. 2016 Oct;34(10):1716-1724. doi: 10.1002/jor.23192. Epub 2016 Feb 26.

4.

SGLT2 inhibitor therapy improves blood glucose but does not prevent diabetic bone disease in diabetic DBA/2J male mice.

Thrailkill KM, Clay Bunn R, Nyman JS, Rettiganti MR, Cockrell GE, Wahl EC, Uppuganti S, Lumpkin CK Jr, Fowlkes JL.

Bone. 2016 Jan;82:101-7. doi: 10.1016/j.bone.2015.07.025. Epub 2015 Jul 23. Erratum in: Bone. 2017 Dec;105:316.

5.

Effects of long-term doxycycline on bone quality and strength in diabetic male DBA/2J mice.

Fowlkes JL, Nyman JS, Bunn RC, Cockrell GE, Wahl EC, Rettiganti MR, Lumpkin CK Jr, Thrailkill KM.

Bone Rep. 2015 Jan;1:16-19.

6.

Cisplatin inhibits bone healing during distraction osteogenesis.

Stine KC, Wahl EC, Liu L, Skinner RA, Vanderschilden J, Bunn RC, Montgomery CO, Suva LJ, Aronson J, Becton DL, Nicholas RW, Swearingen CJ, Lumpkin CK Jr.

J Orthop Res. 2014 Mar;32(3):464-70. doi: 10.1002/jor.22527. Epub 2013 Nov 20.

7.

Loss of functional NADPH oxidase 2 protects against alcohol-induced bone resorption in female p47phox-/- mice.

Mercer KE, Sims CR, Yang CS, Wynne RA, Moutos C, Hogue WR, Lumpkin CK, Suva LJ, Chen JR, Badger TM, Ronis MJ.

Alcohol Clin Exp Res. 2014 Mar;38(3):672-82. doi: 10.1111/acer.12305. Epub 2013 Nov 20.

8.

Osteo-promoting effects of insulin-like growth factor I (IGF-I) in a mouse model of type 1 diabetes.

Fowlkes JL, Nyman JS, Bunn RC, Jo C, Wahl EC, Liu L, Cockrell GE, Morris LM, Lumpkin CK Jr, Thrailkill KM.

Bone. 2013 Nov;57(1):36-40. doi: 10.1016/j.bone.2013.07.017. Epub 2013 Jul 23.

9.

Vitamin D supplementation protects against bone loss associated with chronic alcohol administration in female mice.

Mercer KE, Wynne RA, Lazarenko OP, Lumpkin CK, Hogue WR, Suva LJ, Chen JR, Mason AZ, Badger TM, Ronis MJ.

J Pharmacol Exp Ther. 2012 Nov;343(2):401-12. doi: 10.1124/jpet.112.197038. Epub 2012 Aug 14.

10.

Determinants of undercarboxylated and carboxylated osteocalcin concentrations in type 1 diabetes.

Thrailkill KM, Jo CH, Cockrell GE, Moreau CS, Lumpkin CK Jr, Fowlkes JL.

Osteoporos Int. 2012 Jun;23(6):1799-806. doi: 10.1007/s00198-011-1807-7. Epub 2011 Nov 9.

11.

Distraction osteogenesis in TNF receptor 1 deficient mice is protected from chronic ethanol exposure.

Wahl EC, Aronson J, Liu L, Skinner RA, Ronis MJ, Lumpkin CK Jr.

Alcohol. 2012 Mar;46(2):133-8. doi: 10.1016/j.alcohol.2011.08.007. Epub 2011 Sep 10.

12.

Dysregulation of the intrarenal vitamin D endocytic pathway in a nephropathy-prone mouse model of type 1 diabetes.

Fowlkes JL, Bunn RC, Cockrell GE, Clark LM, Wahl EC, Lumpkin CK, Thrailkill KM.

Exp Diabetes Res. 2011;2011:269378. doi: 10.1155/2011/269378. Epub 2011 May 16.

13.

Increasing duration of type 1 diabetes perturbs the strength-structure relationship and increases brittleness of bone.

Nyman JS, Even JL, Jo CH, Herbert EG, Murry MR, Cockrell GE, Wahl EC, Bunn RC, Lumpkin CK Jr, Fowlkes JL, Thrailkill KM.

Bone. 2011 Apr 1;48(4):733-40. doi: 10.1016/j.bone.2010.12.016. Epub 2010 Dec 23.

14.

Inhibition of NADPH oxidases prevents chronic ethanol-induced bone loss in female rats.

Chen JR, Lazarenko OP, Shankar K, Blackburn ML, Lumpkin CK, Badger TM, Ronis MJ.

J Pharmacol Exp Ther. 2011 Mar;336(3):734-42. doi: 10.1124/jpet.110.175091. Epub 2010 Nov 22.

15.

Palmitate and insulin synergistically induce IL-6 expression in human monocytes.

Bunn RC, Cockrell GE, Ou Y, Thrailkill KM, Lumpkin CK Jr, Fowlkes JL.

Cardiovasc Diabetol. 2010 Nov 5;9:73. doi: 10.1186/1475-2840-9-73.

16.

Disease and gender-specific dysregulation of NGAL and MMP-9 in type 1 diabetes mellitus.

Thrailkill KM, Moreau CS, Cockrell GE, Jo CH, Bunn RC, Morales-Pozzo AE, Lumpkin CK, Fowlkes JL.

Endocrine. 2010 Apr;37(2):336-43. doi: 10.1007/s12020-010-9308-6. Epub 2010 Jan 12.

17.

Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice.

Wahl EC, Aronson J, Liu L, Skinner RA, Miller MJ, Cockrell GE, Fowlkes JL, Thrailkill KM, Bunn RC, Ronis MJ, Lumpkin CK Jr.

Bone. 2010 Feb;46(2):410-7. doi: 10.1016/j.bone.2009.09.011. Epub 2009 Sep 17.

18.

Restoration of regenerative osteoblastogenesis in aged mice: modulation of TNF.

Wahl EC, Aronson J, Liu L, Fowlkes JL, Thrailkill KM, Bunn RC, Skinner RA, Miller MJ, Cockrell GE, Clark LM, Ou Y, Isales CM, Badger TM, Ronis MJ, Sims J, Lumpkin CK Jr.

J Bone Miner Res. 2010 Jan;25(1):114-23. doi: 10.1359/jbmr.090708.

19.

Runt-related transcription factor 2 (RUNX2) and RUNX2-related osteogenic genes are down-regulated throughout osteogenesis in type 1 diabetes mellitus.

Fowlkes JL, Bunn RC, Liu L, Wahl EC, Coleman HN, Cockrell GE, Perrien DS, Lumpkin CK Jr, Thrailkill KM.

Endocrinology. 2008 Apr;149(4):1697-704. Epub 2007 Dec 27.

20.

Chronic ethanol consumption inhibits postlactational anabolic bone rebuilding in female rats.

Shankar K, Hidestrand M, Liu X, Chen JR, Haley R, Perrien DS, Skinner RA, Lumpkin CK Jr, Badger TM, Ronis MJ.

J Bone Miner Res. 2008 Mar;23(3):338-49.

21.

A novel rat model for the study of deficits in bone formation in type-2 diabetes.

Liu Z, Aronson J, Wahl EC, Liu L, Perrien DS, Kern PA, Fowlkes JL, Thrailkill KM, Bunn RC, Cockrell GE, Skinner RA, Lumpkin CK Jr.

Acta Orthop. 2007 Feb;78(1):46-55.

PMID:
17453392
22.

Chronic ethanol exposure inhibits distraction osteogenesis in a mouse model: role of the TNF signaling axis.

Wahl EC, Aronson J, Liu L, Liu Z, Perrien DS, Skinner RA, Badger TM, Ronis MJ, Lumpkin CK Jr.

Toxicol Appl Pharmacol. 2007 May 1;220(3):302-10. Epub 2007 Feb 24.

23.

A novel mouse model for the study of the inhibitory effects of chronic ethanol exposure on direct bone formation.

Wahl EC, Liu L, Perrien DS, Aronson J, Hogue WR, Skinner RA, Hidestrand M, Ronis MJ, Badger TM, Lumpkin CK Jr.

Alcohol. 2006 Jul;39(3):159-67. Epub 2006 Oct 2.

PMID:
17127135
24.

Estradiol protects against ethanol-induced bone loss by inhibiting up-regulation of receptor activator of nuclear factor-kappaB ligand in osteoblasts.

Chen JR, Haley RL, Hidestrand M, Shankar K, Liu X, Lumpkin CK, Simpson PM, Badger TM, Ronis MJ.

J Pharmacol Exp Ther. 2006 Dec;319(3):1182-90. Epub 2006 Sep 13. Erratum in: J Pharmacol Exp Ther. 2007 Feb;320(2):960.

PMID:
16971503
25.

Effects of systemic and local administration of recombinant human IGF-I (rhIGF-I) on de novo bone formation in an aged mouse model.

Fowlkes JL, Thrailkill KM, Liu L, Wahl EC, Bunn RC, Cockrell GE, Perrien DS, Aronson J, Lumpkin CK Jr.

J Bone Miner Res. 2006 Sep;21(9):1359-66.

26.

Different molecular mechanisms underlie ethanol-induced bone loss in cycling and pregnant rats.

Shankar K, Hidestrand M, Haley R, Skinner RA, Hogue W, Jo CH, Simpson P, Lumpkin CK Jr, Aronson J, Badger TM, Ronis MJ.

Endocrinology. 2006 Jan;147(1):166-78. Epub 2005 Oct 20.

PMID:
16239303
27.

Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues.

Thrailkill KM, Lumpkin CK Jr, Bunn RC, Kemp SF, Fowlkes JL.

Am J Physiol Endocrinol Metab. 2005 Nov;289(5):E735-45. Review.

28.

Bone formation is impaired in a model of type 1 diabetes.

Thrailkill KM, Liu L, Wahl EC, Bunn RC, Perrien DS, Cockrell GE, Skinner RA, Hogue WR, Carver AA, Fowlkes JL, Aronson J, Lumpkin CK Jr.

Diabetes. 2005 Oct;54(10):2875-81.

29.

Ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis: a role for the tumor necrosis factor signaling axis.

Wahl EC, Perrien DS, Aronson J, Liu Z, Fletcher TW, Skinner RA, Feige U, Suva LJ, Badger TM, Lumpkin CK Jr.

Alcohol Clin Exp Res. 2005 Aug;29(8):1466-72.

PMID:
16131855
30.

IL-1 and TNF antagonists prevent inhibition of fracture healing by ethanol in rats.

Perrien DS, Wahl EC, Hogue WR, Feige U, Aronson J, Ronis MJ, Badger TM, Lumpkin CK Jr.

Toxicol Sci. 2004 Dec;82(2):656-60. Epub 2004 Oct 6.

PMID:
15470231
31.

Chronic ethanol exposure is associated with a local increase in TNF-alpha and decreased proliferation in the rat distraction gap.

Perrien DS, Liu Z, Wahl EC, Bunn RC, Skinner RA, Aronson J, Fowlkes J, Badger TM, Lumpkin CK Jr.

Cytokine. 2003 Sep 21;23(6):179-89.

PMID:
12967643
32.

Interleukin-1 and tumor necrosis factor antagonists attenuate ethanol-induced inhibition of bone formation in a rat model of distraction osteogenesis.

Perrien DS, Brown EC, Fletcher TW, Irby DJ, Aronson J, Gao GG, Skinner RA, Hogue WR, Feige U, Suva LJ, Ronis MJ, Badger TM, Lumpkin CK Jr.

J Pharmacol Exp Ther. 2002 Dec;303(3):904-8.

PMID:
12438508
33.

Skeletal toxicity associated with chronic ethanol exposure in a rat model using total enteral nutrition.

Brown EC, Perrien DS, Fletcher TW, Irby DJ, Aronson J, Gao GG, Hogue WJ, Skinner RA, Suva LJ, Ronis MJ, Hakkak R, Badger TM, Lumpkin CK Jr.

J Pharmacol Exp Ther. 2002 Jun;301(3):1132-8.

PMID:
12023547
34.

Immunohistochemical study of osteopontin expression during distraction osteogenesis in the rat.

Perrien DS, Brown EC, Aronson J, Skinner RA, Montague DC, Badger TM, Lumpkin CK Jr.

J Histochem Cytochem. 2002 Apr;50(4):567-74.

PMID:
11897810
35.

Skeletal effects of developmental lead exposure in rats.

Ronis MJ, Aronson J, Gao GG, Hogue W, Skinner RA, Badger TM, Lumpkin CK Jr.

Toxicol Sci. 2001 Aug;62(2):321-9.

PMID:
11452145
36.

The effect of aging on distraction osteogenesis in the rat.

Aronson J, Gao GG, Shen XC, McLaren SG, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 2001 May;19(3):421-7.

37.

Development of tensile strength during distraction osteogenesis in a rat model.

Aronson J, Hogue WR, Flahiff CM, Gao GG, Shen XC, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 2001 Jan;19(1):64-9.

38.

Sustained proliferation accompanies distraction osteogenesis in the rat.

Aronson J, Shen XC, Gao GG, Miller F, Quattlebaum T, Skinner RA, Badger TM, Lumpkin CK Jr.

J Orthop Res. 1997 Jul;15(4):563-9.

PMID:
9379266
39.

Rat model of distraction osteogenesis.

Aronson J, Shen XC, Skinner RA, Hogue WR, Badger TM, Lumpkin CK Jr.

J Orthop Res. 1997 Mar;15(2):221-6.

PMID:
9167624
40.

The impact of total enteral nutrition on distraction osteogenesis in a rat model.

Lumpkin CK Jr, Aronson J, Shen XC, Gao GG, Skinner RA, Badger TM.

J Bone Miner Res. 1996 Jul;11(7):962-9.

PMID:
8797117
41.

Acute ethanol and selected growth suppressor transcripts in regenerating rat liver.

Lumpkin CK Jr, Moore TL, Tarpley MD, Taylor JM, Badger TM, McClung JK.

Alcohol. 1995 Jul-Aug;12(4):357-62.

PMID:
7546333
43.

Derangements in calcium-dependent membrane currents in senescent human fibroblasts are associated with overexpression of a novel gene sequence.

Goldstein S, Liu S, Lumpkin CK Jr, Huang M, Lipschitz D, Thweatt R.

Ann N Y Acad Sci. 1994 Dec 15;747:302-12. No abstract available.

PMID:
7847679
45.

Heat shock glycoprotein GP50: product of the retinoic acid-inducible J6 gene.

Henle KJ, Wang SY, Nagle WA, Lumpkin CK.

Exp Cell Res. 1994 Feb;210(2):185-91.

PMID:
8299716
46.
47.

Cytochrome P450 CYP 2E1 induction during chronic alcohol exposure occurs by a two-step mechanism associated with blood alcohol concentrations in rats.

Ronis MJ, Huang J, Crouch J, Mercado C, Irby D, Valentine CR, Lumpkin CK, Ingelman-Sundberg M, Badger TM.

J Pharmacol Exp Ther. 1993 Feb;264(2):944-50.

PMID:
8437134
48.

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat.

Badger TM, Ronis MJ, Lumpkin CK, Valentine CR, Shahare M, Irby D, Huang J, Mercado C, Thomas P, Ingelman-Sundberg M, et al.

J Pharmacol Exp Ther. 1993 Jan;264(1):438-47.

PMID:
8423543
49.

A novel gene encoding a smooth muscle protein is overexpressed in senescent human fibroblasts.

Thweatt R, Lumpkin CK Jr, Goldstein S.

Biochem Biophys Res Commun. 1992 Aug 31;187(1):1-7.

PMID:
1520290
50.

The effects of acute ethanol on growth in rat liver: steady state c-myc transcripts.

Lumpkin CK Jr, Taylor JM, Tarpley MD, Hayden JB, Badger TM, McClung JK.

Alcohol. 1992 May-Jun;9(3):279-82.

PMID:
1605896

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