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Items: 1 to 50 of 68

1.

A Genome-wide Haploid Genetic Screen Identifies Regulators of Glutathione Abundance and Ferroptosis Sensitivity.

Cao JY, Poddar A, Magtanong L, Lumb JH, Mileur TR, Reid MA, Dovey CM, Wang J, Locasale JW, Stone E, Cole SPC, Carette JE, Dixon SJ.

Cell Rep. 2019 Feb 5;26(6):1544-1556.e8. doi: 10.1016/j.celrep.2019.01.043.

2.

An evaluation of methods for the isolation of nontuberculous mycobacteria from patients with cystic fibrosis, bronchiectasis and patients assessed for lung transplantation.

Stephenson D, Perry A, Appleby MR, Lee D, Davison J, Johnston A, Jones AL, Nelson A, Bourke SJ, Thomas MF, De Soyza A, Lordan JL, Lumb J, Robb AE, Samuel JR, Walton KE, Perry JD.

BMC Pulm Med. 2019 Jan 21;19(1):19. doi: 10.1186/s12890-019-0781-2.

3.

Honey bee Royalactin unlocks conserved pluripotency pathway in mammals.

Wan DC, Morgan SL, Spencley AL, Mariano N, Chang EY, Shankar G, Luo Y, Li TH, Huh D, Huynh SK, Garcia JM, Dovey CM, Lumb J, Liu L, Brown KV, Bermudez A, Luong R, Zeng H, Mascetti VL, Pitteri SJ, Wang J, Tu H, Quarta M, Sebastiano V, Nusse R, Rando TA, Carette JE, Bazan JF, Wang KC.

Nat Commun. 2018 Dec 4;9(1):5078. doi: 10.1038/s41467-018-06256-4.

4.

Recent Applications of Diazirines in Chemical Proteomics.

Halloran MW, Lumb JP.

Chemistry. 2019 Apr 1;25(19):4885-4898. doi: 10.1002/chem.201805004. Epub 2019 Jan 23. Review.

PMID:
30444029
5.

A Bioinspired Synthesis of Polyfunctional Indoles.

Huang Z, Kwon O, Huang H, Fadli A, Marat X, Moreau M, Lumb JP.

Angew Chem Int Ed Engl. 2018 Sep 10;57(37):11963-11967. doi: 10.1002/anie.201806490. Epub 2018 Aug 19.

PMID:
29978600
6.

Mechanistic basis of an epistatic interaction reducing age at onset in hereditary spastic paraplegia.

Newton T, Allison R, Edgar JR, Lumb JH, Rodger CE, Manna PT, Rizo T, Kohl Z, Nygren AOH, Arning L, Schüle R, Depienne C, Goldberg L, Frahm C, Stevanin G, Durr A, Schöls L, Winner B, Beetz C, Reid E.

Brain. 2018 May 1;141(5):1286-1299. doi: 10.1093/brain/awy034.

7.

Selectivity in the Aerobic Dearomatization of Phenols: Total Synthesis of Dehydronornuciferine by Chemo- and Regioselective Oxidation.

Esguerra KVN, Lumb JP.

Angew Chem Int Ed Engl. 2018 Feb 5;57(6):1514-1518. doi: 10.1002/anie.201710271. Epub 2018 Jan 16.

PMID:
29271101
8.

DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes.

Lumb JH, Li Q, Popov LM, Ding S, Keith MT, Merrill BD, Greenberg HB, Li JB, Carette JE.

Cell Rep. 2017 Jul 25;20(4):819-831. doi: 10.1016/j.celrep.2017.06.085.

9.

Stopping Aerobic Oxidation in Its Tracks: Chemoselective Synthesis of Benzaldehydes from Methylarenes.

Lumb JP.

Angew Chem Int Ed Engl. 2017 Aug 1;56(32):9276-9277. doi: 10.1002/anie.201704160. Epub 2017 Jun 12.

PMID:
28605566
10.

A chlorine-free protocol for processing germanium.

Glavinović M, Krause M, Yang L, McLeod JA, Liu L, Baines KM, Friščić T, Lumb JP.

Sci Adv. 2017 May 5;3(5):e1700149. doi: 10.1126/sciadv.1700149. eCollection 2017 May.

11.

Second-Order Biomimicry: In Situ Oxidative Self-Processing Converts Copper(I)/Diamine Precursor into a Highly Active Aerobic Oxidation Catalyst.

McCann SD, Lumb JP, Arndtsen BA, Stahl SS.

ACS Cent Sci. 2017 Apr 26;3(4):314-321. doi: 10.1021/acscentsci.7b00022. Epub 2017 Feb 24.

12.

Synthesis of ortho-Azophenols by Formal Dehydrogenative Coupling of Phenols and Hydrazines or Hydrazides.

Esguerra KVN, Lumb JP.

Chemistry. 2017 Jun 27;23(36):8596-8600. doi: 10.1002/chem.201701226. Epub 2017 Apr 11.

PMID:
28332263
13.

Simple Copper Catalysts for the Aerobic Oxidation of Amines: Selectivity Control by the Counterion.

Xu B, Hartigan EM, Feula G, Huang Z, Lumb JP, Arndtsen BA.

Angew Chem Int Ed Engl. 2016 Dec 19;55(51):15802-15806. doi: 10.1002/anie.201609255. Epub 2016 Nov 22.

PMID:
27873434
14.

Asymmetric synthesis of chiral β-alkynyl carbonyl and sulfonyl derivatives via sequential palladium and copper catalysis.

Trost BM, Masters JT, Taft BR, Lumb JP.

Chem Sci. 2016 Sep 16;7(9):6217-6231. Epub 2016 Jun 10.

15.

Synthesis of a 1,3-Bridged Macrobicyclic Enyne via Chemoselective Cycloisomerization Using Palladium-Catalyzed Alkyne-Alkyne Coupling.

Trost BM, Masters JT, Le Vaillant F, Lumb JP.

J Org Chem. 2016 Oct 21;81(20):10023-10028. Epub 2016 Oct 13.

16.

A Catalyst-Controlled Aerobic Coupling of ortho-Quinones and Phenols Applied to the Synthesis of Aryl Ethers.

Huang Z, Lumb JP.

Angew Chem Int Ed Engl. 2016 Sep 12;55(38):11543-7. doi: 10.1002/anie.201606359. Epub 2016 Aug 11.

PMID:
27513295
17.

A bio-inspired synthesis of oxindoles by catalytic aerobic dual C-H functionalization of phenols.

Huang Z, Askari MS, Esguerra KVN, Dai TY, Kwon O, Ottenwaelder X, Lumb JP.

Chem Sci. 2016 Jan 1;7(1):358-369. doi: 10.1039/c5sc02395e. Epub 2015 Oct 6.

18.

Redox-promoted associative assembly of metal-organic materials.

Glavinović M, Qi F, Katsenis AD, Friščić T, Lumb JP.

Chem Sci. 2016 Jan 1;7(1):707-712. doi: 10.1039/c5sc02214b. Epub 2015 Oct 9.

19.

The adherens junctions control susceptibility to Staphylococcus aureus α-toxin.

Popov LM, Marceau CD, Starkl PM, Lumb JH, Shah J, Guerrera D, Cooper RL, Merakou C, Bouley DM, Meng W, Kiyonari H, Takeichi M, Galli SJ, Bagnoli F, Citi S, Carette JE, Amieva MR.

Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):14337-42. doi: 10.1073/pnas.1510265112. Epub 2015 Oct 21.

20.

A Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.

Choma MK, Lumb J, Kozik P, Robinson MS.

PLoS One. 2015 Oct 14;10(10):e0140404. doi: 10.1371/journal.pone.0140404. eCollection 2015.

21.

A Biomimetic Mechanism for the Copper-Catalyzed Aerobic Oxygenation of 4-tert-Butylphenol.

Askari MS, Esguerra KV, Lumb JP, Ottenwaelder X.

Inorg Chem. 2015 Sep 8;54(17):8665-72. doi: 10.1021/acs.inorgchem.5b01297. Epub 2015 Aug 24.

PMID:
26302341
22.

Catalytic aerobic oxidation of phenols to ortho-quinones with air-stable copper precatalysts.

Askari MS, Rodríguez-Solano LA, Proppe A, McAllister B, Lumb JP, Ottenwaelder X.

Dalton Trans. 2015 Jul 21;44(27):12094-7. doi: 10.1039/c5dt00822k.

PMID:
25802218
23.

A TEMPO-free copper-catalyzed aerobic oxidation of alcohols.

Xu B, Lumb JP, Arndtsen BA.

Angew Chem Int Ed Engl. 2015 Mar 27;54(14):4208-11. doi: 10.1002/anie.201411483. Epub 2015 Feb 10.

PMID:
25677693
24.

A bio-inspired total synthesis of tetrahydrofuran lignans.

Albertson AK, Lumb JP.

Angew Chem Int Ed Engl. 2015 Feb 9;54(7):2204-8. doi: 10.1002/anie.201408641. Epub 2015 Jan 12.

PMID:
25582827
25.

Recommendations for the medical evaluation of children prior to adoption in South Africa.

Haeri Mazanderani AF, du Plessis NM, Lumb J, Feucht UD, Myburgh M, Mayaphi SH, Lekalakala MR, Swanepoel de W, Georgakis H, Avenant T.

S Afr Med J. 2014 Jun 19;104(8):544-9. doi: 10.7196/samj.7958.

PMID:
25213841
26.

Controlling the catalytic aerobic oxidation of phenols.

Esguerra KV, Fall Y, Petitjean L, Lumb JP.

J Am Chem Soc. 2014 May 28;136(21):7662-8. doi: 10.1021/ja501789x. Epub 2014 May 16.

PMID:
24784319
27.

Asymmetric synthesis of chiral cycloalkenone derivatives via palladium catalysis.

Trost BM, Masters JT, Lumb JP, Fateen D.

Chem Sci. 2014 Apr 1;5(4):1354-1360.

28.

A biomimetic catalytic aerobic functionalization of phenols.

Esguerra KV, Fall Y, Lumb JP.

Angew Chem Int Ed Engl. 2014 Jun 2;53(23):5877-81. doi: 10.1002/anie.201311103. Epub 2014 Apr 17.

PMID:
24753261
29.

An ESCRT-spastin interaction promotes fission of recycling tubules from the endosome.

Allison R, Lumb JH, Fassier C, Connell JW, Ten Martin D, Seaman MN, Hazan J, Reid E.

J Cell Biol. 2013 Aug 5;202(3):527-43. doi: 10.1083/jcb.201211045. Epub 2013 Jul 29.

31.

Total synthesis of exiguamines A and B inspired by catecholamine chemistry.

Sofiyev V, Lumb JP, Volgraf M, Trauner D.

Chemistry. 2012 Apr 16;18(16):4999-5005. doi: 10.1002/chem.201103605. Epub 2012 Mar 13.

PMID:
22415756
32.

New developments in invasive fungal disease.

Groll AH, Lumb J.

Future Microbiol. 2012 Feb;7(2):179-84. doi: 10.2217/fmb.11.154.

33.

Rab28 function in trypanosomes: interactions with retromer and ESCRT pathways.

Lumb JH, Leung KF, Dubois KN, Field MC.

J Cell Sci. 2011 Nov 15;124(Pt 22):3771-83. doi: 10.1242/jcs.079178. Epub 2011 Nov 18.

34.

Update on invasive fungal disease.

Pagano L, Lumb J.

Future Microbiol. 2011 Sep;6(9):985-9. doi: 10.2217/fmb.11.85.

PMID:
21958139
35.

The AAA ATPase spastin links microtubule severing to membrane modelling.

Lumb JH, Connell JW, Allison R, Reid E.

Biochim Biophys Acta. 2012 Jan;1823(1):192-7. doi: 10.1016/j.bbamcr.2011.08.010. Epub 2011 Aug 25. Review.

36.

Rab23 is a flagellar protein in Trypanosoma brucei.

Lumb JH, Field MC.

BMC Res Notes. 2011 Jun 15;4:190. doi: 10.1186/1756-0500-4-190.

37.

A new strategy for the synthesis of chiral β-alkynyl esters via sequential palladium and copper catalysis.

Trost BM, Taft BR, Masters JT, Lumb JP.

J Am Chem Soc. 2011 Jun 8;133(22):8502-5. doi: 10.1021/ja203171x. Epub 2011 May 16.

38.

Practical issues across the lifetime of heart failure.

Lumb J.

Expert Rev Cardiovasc Ther. 2011 Feb;9(2):151-3. doi: 10.1586/erc.10.193. Erratum in: Expert Rev Cardiovasc Ther. 2011 Mar;9(3):398.

PMID:
21366391
39.

An atom-economic synthesis of nitrogen heterocycles from alkynes.

Trost BM, Lumb JP, Azzarelli JM.

J Am Chem Soc. 2011 Feb 2;133(4):740-3. doi: 10.1021/ja110117g.

40.

Emerging resistance in Gram-negative pathogens and implications for clinical practice.

Cantón R, Lumb J.

Future Microbiol. 2011 Jan;6(1):19-22. doi: 10.2217/fmb.10.150.

41.

Theoretical investigation of the rubicordifolin cascade.

Lumb JP, Krinsky JL, Trauner D.

Org Lett. 2010 Nov 19;12(22):5162-5. doi: 10.1021/ol102157d. Epub 2010 Oct 25.

PMID:
20973524
43.

Exercise intensity does not influence the efficacy of eccentric exercise as a behavioural adjuvant to vaccination.

Edwards KM, Campbell JP, Ring C, Drayson MT, Bosch JA, Downes C, Long JE, Lumb JA, Merry A, Paine NJ, Burns VE.

Brain Behav Immun. 2010 May;24(4):623-30. doi: 10.1016/j.bbi.2010.01.009. Epub 2010 Jan 25. Erratum in: Brain Behav Immun. 2010 Oct;24(7):1220.

PMID:
20102734
44.

Macromolecular trafficking and immune evasion in african trypanosomes.

Field MC, Lumb JH, Adung'a VO, Jones NG, Engstler M.

Int Rev Cell Mol Biol. 2009;278:1-67. doi: 10.1016/S1937-6448(09)78001-3. Review.

PMID:
19815176
45.

Responsiveness of the electronic Personal Assessment Questionnaire-Pelvic Floor (ePAQ-PF).

Jones GL, Radley SC, Lumb J, Farkas A.

Int Urogynecol J Pelvic Floor Dysfunct. 2009 May;20(5):557-64. doi: 10.1007/s00192-008-0790-9. Epub 2009 Feb 3.

PMID:
19189036
46.

Biomimetic synthesis of the IDO inhibitors exiguamine A and B.

Volgraf M, Lumb JP, Brastianos HC, Carr G, Chung MK, Münzel M, Mauk AG, Andersen RJ, Trauner D.

Nat Chem Biol. 2008 Sep;4(9):535-7. doi: 10.1038/nchembio.107.

PMID:
18677305
47.

ortho-Quinone methides from para-quinones: total synthesis of rubioncolin B.

Lumb JP, Choong KC, Trauner D.

J Am Chem Soc. 2008 Jul 23;130(29):9230-1. doi: 10.1021/ja803498r. Epub 2008 Jun 27.

PMID:
18582058
48.

Electronic pelvic floor symptoms assessment: tests of data quality of ePAQ-PF.

Jones GL, Radley SC, Lumb J, Jha S.

Int Urogynecol J Pelvic Floor Dysfunct. 2008 Oct;19(10):1337-47. doi: 10.1007/s00192-008-0655-2. Epub 2008 Jun 14.

PMID:
18553041
49.
50.

HIV and hepatitis co-infection: a consensus for treatment?

Lumb J.

Lancet Infect Dis. 2005 Apr;5(4):202. No abstract available.

PMID:
15834972

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