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Items: 1 to 50 of 69

1.

Exploring Asian Indian views about cancer and participation in cancer research: an evaluation of a culturally tailored educational intervention.

Giri VN, Selvan P, Mohanty S, Lum R, Serrao S, Leader AE.

J Community Genet. 2019 Sep 14. doi: 10.1007/s12687-019-00436-5. [Epub ahead of print]

PMID:
31522341
2.

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound.

Okoye AA, Hansen SG, Vaidya M, Fukazawa Y, Park H, Duell DM, Lum R, Hughes CM, Ventura AB, Ainslie E, Ford JC, Morrow D, Gilbride RM, Legasse AW, Hesselgesser J, Geleziunas R, Li Y, Oswald K, Shoemaker R, Fast R, Bosche WJ, Borate BR, Edlefsen PT, Axthelm MK, Picker LJ, Lifson JD.

Nat Med. 2018 Sep;24(9):1430-1440. doi: 10.1038/s41591-018-0130-7. Epub 2018 Aug 6.

3.

Urinary biomarkers of polycyclic aromatic hydrocarbons in pre- and peri-pubertal girls in Northern California: Predictors of exposure and temporal variability.

Dobraca D, Lum R, Sjödin A, Calafat AM, Laurent CA, Kushi LH, Windham GC.

Environ Res. 2018 Aug;165:46-54. doi: 10.1016/j.envres.2017.11.011. Epub 2018 Apr 14.

4.

Age at Pubertal Onset in Girls and Tobacco Smoke Exposure During Pre- and Postnatal Susceptibility Windows.

Windham GC, Lum R, Voss R, Wolff M, Pinney SM, Teteilbaum SL, Sosnoff CS, Dobraca D, Biro F, Hiatt RA, Greenspan LC, Galvez M, Kushi LH.

Epidemiology. 2017 Sep;28(5):719-727. doi: 10.1097/EDE.0000000000000704.

5.

Exploring Asian Indian and Pakistani views about cancer and participation in cancer genetics research: toward the development of a community genetics intervention.

Leader AE, Mohanty S, Selvan P, Lum R, Giri VN.

J Community Genet. 2018 Jan;9(1):27-35. doi: 10.1007/s12687-017-0312-x. Epub 2017 Jun 28.

6.

Explanations for Not Receiving the Seasonal Influenza Vaccine: An Ontario Canada Based Survey.

Meyer SB, Lum R.

J Health Commun. 2017 Jun;22(6):506-514. doi: 10.1080/10810730.2017.1312720. Epub 2017 Apr 27.

PMID:
28448208
7.

Contributions of the Lectin and Polypeptide Binding Sites of Calreticulin to Its Chaperone Functions in Vitro and in Cells.

Lum R, Ahmad S, Hong SJ, Chapman DC, Kozlov G, Williams DB.

J Biol Chem. 2016 Sep 9;291(37):19631-41. doi: 10.1074/jbc.M116.746321. Epub 2016 Jul 13.

8.

B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers.

Fukazawa Y, Lum R, Okoye AA, Park H, Matsuda K, Bae JY, Hagen SI, Shoemaker R, Deleage C, Lucero C, Morcock D, Swanson T, Legasse AW, Axthelm MK, Hesselgesser J, Geleziunas R, Hirsch VM, Edlefsen PT, Piatak M Jr, Estes JD, Lifson JD, Picker LJ.

Nat Med. 2015 Feb;21(2):132-9. doi: 10.1038/nm.3781. Epub 2015 Jan 19.

9.

Trans [O=Re(V)-OH] core stabilised by chelating N-heterocyclic dicarbene ligands.

Lum R, Zhang H, Zhang W, Bai SQ, Zhao J, Hor TS.

Dalton Trans. 2013 Jan 28;42(4):871-3. doi: 10.1039/c2dt31681a.

PMID:
23172573
10.

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.

Fukazawa Y, Park H, Cameron MJ, Lefebvre F, Lum R, Coombes N, Mahyari E, Hagen SI, Bae JY, Reyes MD 3rd, Swanson T, Legasse AW, Sylwester A, Hansen SG, Smith AT, Stafova P, Shoemaker R, Li Y, Oswald K, Axthelm MK, McDermott A, Ferrari G, Montefiori DC, Edlefsen PT, Piatak M Jr, Lifson JD, Sékaly RP, Picker LJ.

Nat Med. 2012 Nov;18(11):1673-81. doi: 10.1038/nm.2934. Epub 2012 Sep 9.

11.

Naive T cells are dispensable for memory CD4+ T cell homeostasis in progressive simian immunodeficiency virus infection.

Okoye AA, Rohankhedkar M, Abana C, Pattenn A, Reyes M, Pexton C, Lum R, Sylwester A, Planer SL, Legasse A, Park BS, Piatak M Jr, Lifson JD, Axthelm MK, Picker LJ.

J Exp Med. 2012 Apr 9;209(4):641-51. doi: 10.1084/jem.20112071. Epub 2012 Mar 26.

12.

Body burdens of brominated flame retardants and other persistent organo-halogenated compounds and their descriptors in US girls.

Windham GC, Pinney SM, Sjodin A, Lum R, Jones RS, Needham LL, Biro FM, Hiatt RA, Kushi LH.

Environ Res. 2010 Apr;110(3):251-7. doi: 10.1016/j.envres.2010.01.004. Epub 2010 Feb 2.

13.

Profound CD4+/CCR5+ T cell expansion is induced by CD8+ lymphocyte depletion but does not account for accelerated SIV pathogenesis.

Okoye A, Park H, Rohankhedkar M, Coyne-Johnson L, Lum R, Walker JM, Planer SL, Legasse AW, Sylwester AW, Piatak M Jr, Lifson JD, Sodora DL, Villinger F, Axthelm MK, Schmitz JE, Picker LJ.

J Exp Med. 2009 Jul 6;206(7):1575-88. doi: 10.1084/jem.20090356. Epub 2009 Jun 22.

14.

Remodeling of protein aggregates by Hsp104.

Glover JR, Lum R.

Protein Pept Lett. 2009;16(6):587-97. Review.

PMID:
19519516
15.

Design, synthesis, and structure-activity relationships of novel insulin receptor tyrosine kinase activators.

Lum RT, Cheng M, Cristobal CP, Goldfine ID, Evans JL, Keck JG, Macsata RW, Manchem VP, Matsumoto Y, Park SJ, Rao SS, Robinson L, Shi S, Spevak WR, Schow SR.

J Med Chem. 2008 Oct 9;51(19):6173-87. doi: 10.1021/jm800600v. Epub 2008 Sep 13.

PMID:
18788731
16.

Peptide and protein binding in the axial channel of Hsp104. Insights into the mechanism of protein unfolding.

Lum R, Niggemann M, Glover JR.

J Biol Chem. 2008 Oct 31;283(44):30139-50. doi: 10.1074/jbc.M804849200. Epub 2008 Aug 28.

17.

5-Substituted isophthalamides as insulin receptor sensitizers.

Robinson L, Bajjalieh S, Cairns N, Lum RT, Macsata RW, Manchem VP, Park SJ, Rao S, Schow SR, Shi S, Spevak WR.

Bioorg Med Chem Lett. 2008 Jun 15;18(12):3492-4. doi: 10.1016/j.bmcl.2008.05.031. Epub 2008 May 15.

PMID:
18513965
18.

Clinical teaching capacity in New Zealand general practice.

Pullon S, Lum R.

N Z Med J. 2008 Jan 25;121(1268):U2895.

PMID:
18256711
19.

Progressive CD4+ central memory T cell decline results in CD4+ effector memory insufficiency and overt disease in chronic SIV infection.

Okoye A, Meier-Schellersheim M, Brenchley JM, Hagen SI, Walker JM, Rohankhedkar M, Lum R, Edgar JB, Planer SL, Legasse A, Sylwester AW, Piatak M Jr, Lifson JD, Maino VC, Sodora DL, Douek DC, Axthelm MK, Grossman Z, Picker LJ.

J Exp Med. 2007 Sep 3;204(9):2171-85. Epub 2007 Aug 27. Erratum in: J Exp Med. 2007 Oct;204(10):2493.

20.

Clinical and genetic risk factors for pneumonia in systemic lupus erythematosus.

Kinder BW, Freemer MM, King TE Jr, Lum RF, Nititham J, Taylor K, Edberg JC, Bridges SL Jr, Criswell LA.

Arthritis Rheum. 2007 Aug;56(8):2679-86.

21.

Interaction between smoking, the shared epitope, and anti-cyclic citrullinated peptide: a mixed picture in three large North American rheumatoid arthritis cohorts.

Lee HS, Irigoyen P, Kern M, Lee A, Batliwalla F, Khalili H, Wolfe F, Lum RF, Massarotti E, Weisman M, Bombardier C, Karlson EW, Criswell LA, Vlietinck R, Gregersen PK.

Arthritis Rheum. 2007 Jun;56(6):1745-53.

22.

Association of PDCD1 genetic variation with risk and clinical manifestations of systemic lupus erythematosus in a multiethnic cohort.

Thorburn CM, Prokunina-Olsson L, Sterba KA, Lum RF, Seldin MF, Alarcon-Riquelme ME, Criswell LA.

Genes Immun. 2007 Jun;8(4):279-87. Epub 2007 Mar 8.

23.

Dissecting the heterogeneity of rheumatoid arthritis through linkage analysis of quantitative traits.

Criswell LA, Chen WV, Jawaheer D, Lum RF, Wener MH, Gu X, Gregersen PK, Amos CI.

Arthritis Rheum. 2007 Jan;56(1):58-68.

24.

Influence of male sex on disease phenotype in familial rheumatoid arthritis.

Jawaheer D, Lum RF, Gregersen PK, Criswell LA.

Arthritis Rheum. 2006 Oct;54(10):3087-94.

25.

Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian women.

Criswell LA, Saag KG, Mikuls TR, Cerhan JR, Merlino LA, Lum RF, Pfeiffer KA, Woehl B, Seldin MF.

Ann Rheum Dis. 2006 Sep;65(9):1163-7. Epub 2006 Aug 3.

26.

Ages of onset suggestive of genetic anticipation in rheumatoid arthritis multicase sibships can be explained by observational bias.

Deighton C, Criswell LA, Lum RF, Silman A.

Rheumatology (Oxford). 2007 Jan;46(1):120-3. Epub 2006 Jun 4.

PMID:
16754627
27.

Regulation of anti-cyclic citrullinated peptide antibodies in rheumatoid arthritis: contrasting effects of HLA-DR3 and the shared epitope alleles.

Irigoyen P, Lee AT, Wener MH, Li W, Kern M, Batliwalla F, Lum RF, Massarotti E, Weisman M, Bombardier C, Remmers EF, Kastner DL, Seldin MF, Criswell LA, Gregersen PK.

Arthritis Rheum. 2005 Dec;52(12):3813-8.

28.

Refining the complex rheumatoid arthritis phenotype based on specificity of the HLA-DRB1 shared epitope for antibodies to citrullinated proteins.

Huizinga TW, Amos CI, van der Helm-van Mil AH, Chen W, van Gaalen FA, Jawaheer D, Schreuder GM, Wener M, Breedveld FC, Ahmad N, Lum RF, de Vries RR, Gregersen PK, Toes RE, Criswell LA.

Arthritis Rheum. 2005 Nov;52(11):3433-8.

29.

Target-related affinity profiling: Telik's lead discovery technology.

Beroza P, Damodaran K, Lum RT.

Curr Top Med Chem. 2005;5(4):371-81. Review.

PMID:
15892680
30.

Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes.

Criswell LA, Pfeiffer KA, Lum RF, Gonzales B, Novitzke J, Kern M, Moser KL, Begovich AB, Carlton VE, Li W, Lee AT, Ortmann W, Behrens TW, Gregersen PK.

Am J Hum Genet. 2005 Apr;76(4):561-71. Epub 2005 Feb 17.

31.

Insufficient production and tissue delivery of CD4+ memory T cells in rapidly progressive simian immunodeficiency virus infection.

Picker LJ, Hagen SI, Lum R, Reed-Inderbitzin EF, Daly LM, Sylwester AW, Walker JM, Siess DC, Piatak M Jr, Wang C, Allison DB, Maino VC, Lifson JD, Kodama T, Axthelm MK.

J Exp Med. 2004 Nov 15;200(10):1299-314.

32.

Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis.

Gorman JD, David-Vaudey E, Pai M, Lum RF, Criswell LA.

Arthritis Rheum. 2004 Nov;50(11):3476-84.

33.

The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept.

Criswell LA, Lum RF, Turner KN, Woehl B, Zhu Y, Wang J, Tiwari HK, Edberg JC, Kimberly RP, Moreland LW, Seldin MF, Bridges SL Jr.

Arthritis Rheum. 2004 Sep;50(9):2750-6.

34.

Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints.

Hsu N, Cai D, Damodaran K, Gomez RF, Keck JG, Laborde E, Lum RT, Macke TJ, Martin G, Schow SR, Simon RJ, Villar HO, Wick MM, Beroza P.

J Med Chem. 2004 Sep 23;47(20):4875-80.

PMID:
15369391
35.

In vitro and in vivo prevention of HIV protease inhibitor-induced insulin resistance by a novel small molecule insulin receptor activator.

Cheng M, Chen S, Schow SR, Manchem VP, Spevak WR, Cristobal CP, Shi S, Macsata RW, Lum RT, Goldfine ID, Keck JG.

J Cell Biochem. 2004 Aug 15;92(6):1234-45.

PMID:
15258906
36.

Evidence for an unfolding/threading mechanism for protein disaggregation by Saccharomyces cerevisiae Hsp104.

Lum R, Tkach JM, Vierling E, Glover JR.

J Biol Chem. 2004 Jul 9;279(28):29139-46. Epub 2004 May 5.

38.

Clustering of disease features within 512 multicase rheumatoid arthritis families.

Jawaheer D, Lum RF, Amos CI, Gregersen PK, Criswell LA.

Arthritis Rheum. 2004 Mar;50(3):736-41.

39.

Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patients.

Gorman JD, Lum RF, Chen JJ, Suarez-Almazor ME, Thomson G, Criswell LA.

Arthritis Rheum. 2004 Feb;50(2):400-12.

40.

Phase I study of TLK286 (glutathione S-transferase P1-1 activated glutathione analogue) in advanced refractory solid malignancies.

Rosen LS, Brown J, Laxa B, Boulos L, Reiswig L, Henner WD, Lum RT, Schow SR, Maack CA, Keck JG, Mascavage JC, Dombroski JA, Gomez RF, Brown GL.

Clin Cancer Res. 2003 May;9(5):1628-38.

41.

Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families.

Jawaheer D, Seldin MF, Amos CI, Chen WV, Shigeta R, Etzel C, Damle A, Xiao X, Chen D, Lum RF, Monteiro J, Kern M, Criswell LA, Albani S, Nelson JL, Clegg DO, Pope R, Schroeder HW Jr, Bridges SL Jr, Pisetsky DS, Ward R, Kastner DL, Wilder RL, Pincus T, Callahan LF, Flemming D, Wener MH, Gregersen PK; North American Rheumatoid Arthritis Consortium.

Arthritis Rheum. 2003 Apr;48(4):906-16.

42.

Association of angiotensin-converting enzyme polymorphisms with systemic lupus erythematosus and nephritis: analysis of 644 SLE families.

Parsa A, Peden E, Lum RF, Seligman VA, Olson JL, Li H, Seldin MF, Criswell LA.

Genes Immun. 2002 Oct;3 Suppl 1:S42-6.

43.

Demographic differences in the development of lupus nephritis: a retrospective analysis.

Seligman VA, Lum RF, Olson JL, Li H, Criswell LA.

Am J Med. 2002 Jun 15;112(9):726-9. No abstract available.

PMID:
12079714
44.

Development and homeostasis of T cell memory in rhesus macaque.

Pitcher CJ, Hagen SI, Walker JM, Lum R, Mitchell BL, Maino VC, Axthelm MK, Picker LJ.

J Immunol. 2002 Jan 1;168(1):29-43.

45.

A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo.

Manchem VP, Goldfine ID, Kohanski RA, Cristobal CP, Lum RT, Schow SR, Shi S, Spevak WR, Laborde E, Toavs DK, Villar HO, Wick MM, Kozlowski MR.

Diabetes. 2001 Apr;50(4):824-30.

46.

The Fcgamma receptor IIIA-158F allele is a major risk factor for the development of lupus nephritis among Caucasians but not non-Caucasians.

Seligman VA, Suarez C, Lum R, Inda SE, Lin D, Li H, Olson JL, Seldin MF, Criswell LA.

Arthritis Rheum. 2001 Mar;44(3):618-25.

47.

Dibasic inhibitors of human mast cell tryptase. Part 1: synthesis and optimization of a novel class of inhibitors.

Rice KD, Gangloff AR, Kuo EY, Dener JM, Wang VR, Lum R, Newcomb WS, Havel C, Putnam D, Cregar L, Wong M, Warne RL.

Bioorg Med Chem Lett. 2000 Oct 16;10(20):2357-60.

PMID:
11055355
48.

Influence of different forms of fluid shear stress on vascular endothelial TGF-beta1 mRNA expression.

Lum RM, Wiley LM, Barakat AI.

Int J Mol Med. 2000 Jun;5(6):635-41.

PMID:
10812015
49.

The importance of local-regional radiotherapy with conventional or high-dose chemotherapy in the management of breast cancer patients with > or = 10 positive axillary nodes.

Jabro G, Wazer DE, Ruthazer R, Lum R, Sklar N, Goldman D, Enegess D, Erban J.

Int J Radiat Oncol Biol Phys. 1999 May 1;44(2):273-80.

PMID:
10760419
50.

A new structural class of proteasome inhibitors that prevent NF-kappa B activation.

Lum RT, Kerwar SS, Meyer SM, Nelson MG, Schow SR, Shiffman D, Wick MM, Joly A.

Biochem Pharmacol. 1998 May 1;55(9):1391-7.

PMID:
10076530

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