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Items: 24

1.

Enterovirus Competition Assay to Assess Replication Fitness.

Lulla V, Firth AE.

Bio Protoc. 2019 Jun 3;9(10). doi: 10.21769/BioProtoc.3233. Epub 2019 May 20.

2.

An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells.

Lulla V, Dinan AM, Hosmillo M, Chaudhry Y, Sherry L, Irigoyen N, Nayak KM, Stonehouse NJ, Zilbauer M, Goodfellow I, Firth AE.

Nat Microbiol. 2019 Feb;4(2):280-292. doi: 10.1038/s41564-018-0297-1. Epub 2018 Nov 26.

3.

Mutation of CD2AP and SH3KBP1 Binding Motif in Alphavirus nsP3 Hypervariable Domain Results in Attenuated Virus.

Mutso M, Morro AM, Smedberg C, Kasvandik S, Aquilimeba M, Teppor M, Tarve L, Lulla A, Lulla V, Saul S, Thaa B, McInerney GM, Merits A, Varjak M.

Viruses. 2018 Apr 27;10(5). pii: E226. doi: 10.3390/v10050226.

4.

Timeliness of Proteolytic Events Is Prerequisite for Efficient Functioning of the Alphaviral Replicase.

Lulla V, Karo-Astover L, Rausalu K, Saul S, Merits A, Lulla A.

J Virol. 2018 Jun 29;92(14). pii: e00151-18. doi: 10.1128/JVI.00151-18. Print 2018 Jul 15.

5.

Protective efficacy of multivalent replication-abortive vaccine strains in horses against African horse sickness virus challenge.

Lulla V, Losada A, Lecollinet S, Kerviel A, Lilin T, Sailleau C, Beck C, Zientara S, Roy P.

Vaccine. 2017 Jul 24;35(33):4262-4269. doi: 10.1016/j.vaccine.2017.06.023. Epub 2017 Jun 29.

6.

Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus.

Ramachandran M, Yu D, Dyczynski M, Baskaran S, Zhang L, Lulla A, Lulla V, Saul S, Nelander S, Dimberg A, Merits A, Leja-Jarblad J, Essand M.

Clin Cancer Res. 2017 Mar 15;23(6):1519-1530. doi: 10.1158/1078-0432.CCR-16-0925. Epub 2016 Sep 16.

7.

Correction for Utt et al., Mutations Conferring a Noncytotoxic Phenotype on Chikungunya Virus Replicons Compromise Enzymatic Properties of Nonstructural Protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A.

J Virol. 2016 Aug 12;90(17):8030. doi: 10.1128/JVI.01167-16. Print 2016 Sep 1. No abstract available.

8.

Assembly of Replication-Incompetent African Horse Sickness Virus Particles: Rational Design of Vaccines for All Serotypes.

Lulla V, Lulla A, Wernike K, Aebischer A, Beer M, Roy P.

J Virol. 2016 Jul 27;90(16):7405-7414. doi: 10.1128/JVI.00548-16. Print 2016 Aug 15.

9.

The SD1 Subdomain of Venezuelan Equine Encephalitis Virus Capsid Protein Plays a Critical Role in Nucleocapsid and Particle Assembly.

Reynaud JM, Lulla V, Kim DY, Frolova EI, Frolov I.

J Virol. 2015 Dec 9;90(4):2008-20. doi: 10.1128/JVI.02680-15. Print 2016 Feb 15.

10.

Mutations conferring a noncytotoxic phenotype on chikungunya virus replicons compromise enzymatic properties of nonstructural protein 2.

Utt A, Das PK, Varjak M, Lulla V, Lulla A, Merits A.

J Virol. 2015 Mar;89(6):3145-62. doi: 10.1128/JVI.03213-14. Epub 2014 Dec 31. Erratum in: J Virol. 2016 Aug 12;90(17 ):8030.

11.

Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.

Her Z, Teng TS, Tan JJ, Teo TH, Kam YW, Lum FM, Lee WW, Gabriel C, Melchiotti R, Andiappan AK, Lulla V, Lulla A, Win MK, Chow A, Biswas SK, Leo YS, Lecuit M, Merits A, Rénia L, Ng LF.

EMBO Mol Med. 2015 Jan;7(1):24-41. doi: 10.15252/emmm.201404459.

12.

Prime-boost immunization strategies against Chikungunya virus.

Hallengärd D, Lum FM, Kümmerer BM, Lulla A, Lulla V, García-Arriaza J, Fazakerley JK, Roques P, Le Grand R, Merits A, Ng LF, Esteban M, Liljeström P.

J Virol. 2014 Nov;88(22):13333-43. doi: 10.1128/JVI.01926-14. Epub 2014 Sep 10.

13.

Novel attenuated Chikungunya vaccine candidates elicit protective immunity in C57BL/6 mice.

Hallengärd D, Kakoulidou M, Lulla A, Kümmerer BM, Johansson DX, Mutso M, Lulla V, Fazakerley JK, Roques P, Le Grand R, Merits A, Liljeström P.

J Virol. 2014 Mar;88(5):2858-66. doi: 10.1128/JVI.03453-13. Epub 2013 Dec 26.

14.

RIG-I and MDA-5 detection of viral RNA-dependent RNA polymerase activity restricts positive-strand RNA virus replication.

Nikonov A, Mölder T, Sikut R, Kiiver K, Männik A, Toots U, Lulla A, Lulla V, Utt A, Merits A, Ustav M.

PLoS Pathog. 2013;9(9):e1003610. doi: 10.1371/journal.ppat.1003610. Epub 2013 Sep 5.

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16.

Presentation overrides specificity: probing the plasticity of alphaviral proteolytic activity through mutational analysis.

Lulla V, Karo-Astover L, Rausalu K, Merits A, Lulla A.

J Virol. 2013 Sep;87(18):10207-20. doi: 10.1128/JVI.01485-13. Epub 2013 Jul 17.

17.

Virus replicon particle based Chikungunya virus neutralization assay using Gaussia luciferase as readout.

Gläsker S, Lulla A, Lulla V, Couderc T, Drexler JF, Liljeström P, Lecuit M, Drosten C, Merits A, Kümmerer BM.

Virol J. 2013 Jul 15;10:235. doi: 10.1186/1743-422X-10-235.

18.

A pathogenic role for CD4+ T cells during Chikungunya virus infection in mice.

Teo TH, Lum FM, Claser C, Lulla V, Lulla A, Merits A, Rénia L, Ng LF.

J Immunol. 2013 Jan 1;190(1):259-69. doi: 10.4049/jimmunol.1202177. Epub 2012 Dec 3.

19.

Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein.

Lulla A, Lulla V, Merits A.

J Virol. 2012 Jan;86(1):553-65. doi: 10.1128/JVI.05195-11. Epub 2011 Oct 26.

20.

Properties and use of novel replication-competent vectors based on Semliki Forest virus.

Rausalu K, Iofik A, Ulper L, Karo-Astover L, Lulla V, Merits A.

Virol J. 2009 Mar 24;6:33. doi: 10.1186/1743-422X-6-33.

21.

Molecular defects caused by temperature-sensitive mutations in Semliki Forest virus nsP1.

Lulla V, Sawicki DL, Sawicki SG, Lulla A, Merits A, Ahola T.

J Virol. 2008 Sep;82(18):9236-44. doi: 10.1128/JVI.00711-08. Epub 2008 Jul 2.

22.

Insertion of EGFP into the replicase gene of Semliki Forest virus results in a novel, genetically stable marker virus.

Tamberg N, Lulla V, Fragkoudis R, Lulla A, Fazakerley JK, Merits A.

J Gen Virol. 2007 Apr;88(Pt 4):1225-30.

23.

Molecular determinants of substrate specificity for Semliki Forest virus nonstructural protease.

Lulla A, Lulla V, Tints K, Ahola T, Merits A.

J Virol. 2006 Jun;80(11):5413-22.

24.

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis.

Lulla V, Merits A, Sarin P, Kääriäinen L, Keränen S, Ahola T.

J Virol. 2006 Mar;80(6):3108-11.

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