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Items: 1 to 50 of 442

1.

Dose-Dependent Effect of Enzyme Replacement Therapy on Neutralizing Antidrug Antibody Titers and Clinical Outcome in Patients with Fabry Disease.

Lenders M, Neußer LP, Rudnicki M, Nordbeck P, Canaan-Kühl S, Nowak A, Cybulla M, Schmitz B, Lukas J, Wanner C, Brand SM, Brand E.

J Am Soc Nephrol. 2018 Nov 1. pii: ASN.2018070740. doi: 10.1681/ASN.2018070740. [Epub ahead of print]

PMID:
30385651
2.

Positive Antithyroid Antibodies and Nonsuppressed TSH Are Associated with Thyroid Cancer: A Retrospective Cross-Sectional Study.

Krátký J, Ježková J, Kosák M, Vítková H, Bartáková J, Mráz M, Lukáš J, Límanová Z, Jiskra J.

Int J Endocrinol. 2018 Sep 6;2018:9793850. doi: 10.1155/2018/9793850. eCollection 2018.

3.

Using a robotic fish to investigate individual differences in social responsiveness in the guppy.

Bierbach D, Landgraf T, Romanczuk P, Lukas J, Nguyen H, Wolf M, Krause J.

R Soc Open Sci. 2018 Aug 8;5(8):181026. doi: 10.1098/rsos.181026. eCollection 2018 Aug.

4.

Total thyroidectomy (Tx) versus thionamides (antithyroid drugs) in patients with moderate-to-severe Graves' ophthalmopathy - a 1-year follow-up: study protocol for a randomized controlled trial.

Brammen L, Riss P, Lukas J, Gessl A, Dunkler D, Li S, Leisser A, Rezar-Dreindl S, Eibenberger K, Selberherr A, Scheuba C, Papp A.

Trials. 2018 Sep 15;19(1):495. doi: 10.1186/s13063-018-2876-0.

5.

DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy.

Bennetzen MV, Kosar M, Bunkenborg J, Payne MR, Bartkova J, Lindström MS, Lukas J, Andersen JS, Bartek J, Larsen DH.

Cell Cycle. 2018;17(17):2146-2163. doi: 10.1080/15384101.2018.1515552. Epub 2018 Sep 22.

PMID:
30196736
6.

Time Scaling for In Vitro-In Vivo Correlation: the Inverse Release Function (IRF) Approach.

Cardot JM, Lukas JC, Muniz P.

AAPS J. 2018 Aug 29;20(6):95. doi: 10.1208/s12248-018-0250-5.

PMID:
30159772
7.

Treatment of mucosa associated lymphoid tissue lymphoma with a long-term once-weekly regimen of oral azithromycin: Results from the phase II MALT-A trial.

Lagler H, Kiesewetter B, Dolak W, Obermueller M, Simonitsch-Klupp I, Lukas J, Neuper O, Lamm WW, Mayerhoefer ME, Raderer M.

Hematol Oncol. 2018 Aug 28. doi: 10.1002/hon.2555. [Epub ahead of print]

PMID:
30153341
8.

Extending Endovascular Embolization to Type A Spinal Perimedullary Arteriovenous Fistula Using Liquid Embolic Agent: Technical Nuances, Challenges and Initial Outcome.

Malik V, Kannath SK, Rajan JE, Lukas J.

World Neurosurg. 2018 Nov;119:267-273. doi: 10.1016/j.wneu.2018.08.021. Epub 2018 Aug 15.

PMID:
30118864
9.

Job satisfaction among disabled people in the sheltered workshop: Differential analysis.

Lukas JF, Lizasoain L, Galarreta J, Etxeberria J.

J Appl Res Intellect Disabil. 2018 Nov;31(6):1174-1185. doi: 10.1111/jar.12492. Epub 2018 Jun 27.

PMID:
29947455
10.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, Typas D, Lammers M, Mailand N, Nussenzweig A, Lukas J, Choudhary C.

Cell. 2018 May 3;173(4):972-988.e23. doi: 10.1016/j.cell.2018.03.050. Epub 2018 Apr 12.

PMID:
29656893
11.

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability.

Galanos P, Pappas G, Polyzos A, Kotsinas A, Svolaki I, Giakoumakis NN, Glytsou C, Pateras IS, Swain U, Souliotis VL, Georgakilas AG, Geacintov N, Scorrano L, Lukas C, Lukas J, Livneh Z, Lygerou Z, Chowdhury D, Sørensen CS, Bartek J, Gorgoulis VG.

Genome Biol. 2018 Mar 16;19(1):37. doi: 10.1186/s13059-018-1401-9.

12.

In Vitro Enzyme Measurement to Test Pharmacological Chaperone Responsiveness in Fabry and Pompe Disease.

Lukas J, Knospe AM, Seemann S, Citro V, Cubellis MV, Rolfs A.

J Vis Exp. 2017 Dec 20;(130). doi: 10.3791/56550.

PMID:
29286471
13.

Redox-sensitive alteration of replisome architecture safeguards genome integrity.

Somyajit K, Gupta R, Sedlackova H, Neelsen KJ, Ochs F, Rask MB, Choudhary C, Lukas J.

Science. 2017 Nov 10;358(6364):797-802. doi: 10.1126/science.aao3172.

PMID:
29123070
14.

Glucosylsphingosine Causes Hematological and Visceral Changes in Mice-Evidence for a Pathophysiological Role in Gaucher Disease.

Lukas J, Cozma C, Yang F, Kramp G, Meyer A, Neßlauer AM, Eichler S, Böttcher T, Witt M, Bräuer AU, Kropp P, Rolfs A.

Int J Mol Sci. 2017 Oct 20;18(10). pii: E2192. doi: 10.3390/ijms18102192.

15.

Model Informed Pediatric Development Applied to Bilastine: Ontogenic PK Model Development, Dose Selection for First Time in Children and PK Study Design.

Vozmediano V, Sologuren A, Lukas JC, Leal N, Rodriguez M.

Pharm Res. 2017 Dec;34(12):2720-2734. doi: 10.1007/s11095-017-2248-6. Epub 2017 Oct 2.

PMID:
28971281
16.

Repeat: a framework to assess empirical reproducibility in biomedical research.

McIntosh LD, Juehne A, Vitale CRH, Liu X, Alcoser R, Lukas JC, Evanoff B.

BMC Med Res Methodol. 2017 Sep 18;17(1):143. doi: 10.1186/s12874-017-0377-6.

17.

Immunohistochemical expression of cereblon and MUM1 as potential predictive markers of response to lenalidomide in extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma).

Kiesewetter B, Simonitsch-Klupp I, Kornauth C, Dolak W, Lukas J, Mayerhoefer ME, Raderer M.

Hematol Oncol. 2018 Feb;36(1):62-67. doi: 10.1002/hon.2472. Epub 2017 Aug 22.

PMID:
28833354
18.

ADAM23 promotes neuronal differentiation of human neural progenitor cells.

Markus-Koch A, Schmitt O, Seemann S, Lukas J, Koczan D, Ernst M, Fuellen G, Wree A, Rolfs A, Luo J.

Cell Mol Biol Lett. 2017 Aug 18;22:16. doi: 10.1186/s11658-017-0045-1. eCollection 2017.

19.

Fluorescent probes for selective protein labeling in lysosomes: a case of α-galactosidase A.

Bohl C, Pomorski A, Seemann S, Knospe AM, Zheng C, Krężel A, Rolfs A, Lukas J.

FASEB J. 2017 Dec;31(12):5258-5267. doi: 10.1096/fj.201700058RRRR. Epub 2017 Aug 15.

PMID:
28821638
20.

Enhanced Degradation of TCE on a Superfund Site Using Endophyte-Assisted Poplar Tree Phytoremediation.

Doty SL, Freeman JL, Cohu CM, Burken JG, Firrincieli A, Simon A, Khan Z, Isebrands JG, Lukas J, Blaylock MJ.

Environ Sci Technol. 2017 Sep 5;51(17):10050-10058. doi: 10.1021/acs.est.7b01504. Epub 2017 Aug 11.

PMID:
28737929
21.

C26-Ceramide as highly sensitive biomarker for the diagnosis of Farber Disease.

Cozma C, Iurașcu MI, Eichler S, Hovakimyan M, Brandau O, Zielke S, Böttcher T, Giese AK, Lukas J, Rolfs A.

Sci Rep. 2017 Jul 21;7(1):6149. doi: 10.1038/s41598-017-06604-2.

22.

A pilot phase II study of ofatumumab monotherapy for extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) lymphoma.

Kiesewetter B, Neuper O, Mayerhoefer ME, Dolak W, Lukas J, Simonitsch-Klupp I, Raderer M.

Hematol Oncol. 2018 Feb;36(1):49-55. doi: 10.1002/hon.2454. Epub 2017 Jul 10.

PMID:
28695630
23.

On the occurrence of three non-native cichlid species including the first record of a feral population of Pelmatolapia (Tilapia) mariae (Boulenger, 1899) in Europe.

Lukas JAY, Jourdan J, Kalinkat G, Emde S, Miesen FW, Jüngling H, Cocchiararo B, Bierbach D.

R Soc Open Sci. 2017 Jun 21;4(6):170160. doi: 10.1098/rsos.170160. eCollection 2017 Jun.

24.

Replication Catastrophe: When a Checkpoint Fails because of Exhaustion.

Toledo L, Neelsen KJ, Lukas J.

Mol Cell. 2017 Jun 15;66(6):735-749. doi: 10.1016/j.molcel.2017.05.001. Review.

25.

Bilateral Infiltrative Dacryoadenitis and Granulomatous Pneumonia in an 11-Year-Old Boy: A Case Report.

Diesner SC, Lukas J, Stifter E, Raimann A, Nachbaur E, Eiwegger T, Renner S, Emminger W, Geleff S, Szepfalusi Z.

Klin Padiatr. 2017 Mar;229(2):96-99. doi: 10.1055/s-0043-100381. Epub 2017 Apr 25. No abstract available.

PMID:
28444655
26.

Treating Prey With Glyphosate Does Not Alter the Demographic Parameters and Predation of the Harmonia axyridis (Coleoptera: Coccinellidae).

Saska P, Skuhrovec J, Lukáš J, Vlach M, Chi H, Tuan SJ, Honek A.

J Econ Entomol. 2017 Apr 1;110(2):392-399. doi: 10.1093/jee/tow325.

PMID:
28131988
27.

Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks.

Sotiriou SK, Kamileri I, Lugli N, Evangelou K, Da-Ré C, Huber F, Padayachy L, Tardy S, Nicati NL, Barriot S, Ochs F, Lukas C, Lukas J, Gorgoulis VG, Scapozza L, Halazonetis TD.

Mol Cell. 2016 Dec 15;64(6):1127-1134. doi: 10.1016/j.molcel.2016.10.038.

28.

Profiling DNA damage response following mitotic perturbations.

S Pedersen R, Karemore G, Gudjonsson T, Rask MB, Neumann B, Hériché JK, Pepperkok R, Ellenberg J, Gerlich DW, Lukas J, Lukas C.

Nat Commun. 2016 Dec 15;7:13887. doi: 10.1038/ncomms13887.

29.

The Large Phenotypic Spectrum of Fabry Disease Requires Graduated Diagnosis and Personalized Therapy: A Meta-Analysis Can Help to Differentiate Missense Mutations.

Citro V, Cammisa M, Liguori L, Cimmaruta C, Lukas J, Cubellis MV, Andreotti G.

Int J Mol Sci. 2016 Dec 1;17(12). pii: E2010. Review.

31.

Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease.

Citro V, Peña-García J, den-Haan H, Pérez-Sánchez H, Del Prete R, Liguori L, Cimmaruta C, Lukas J, Cubellis MV, Andreotti G.

PLoS One. 2016 Oct 27;11(10):e0165463. doi: 10.1371/journal.pone.0165463. eCollection 2016.

32.

Can Interim 18F-FDG PET or Diffusion-Weighted MRI Predict End-of-Treatment Outcome in FDG-Avid MALT Lymphoma After Rituximab-Based Therapy?: A Preliminary Study in 15 Patients.

Mayerhoefer ME, Karanikas G, Kletter K, Kiesewetter B, Weber M, Rausch I, Pones M, Simonitsch-Klupp I, Müllauer L, Dolak W, Lukas J, Raderer M.

Clin Nucl Med. 2016 Nov;41(11):837-843.

PMID:
27648705
33.

Gender Aspects in Extranodal Marginal Zone B-Cell Lymphoma of the Mucosa-Associated Lymphoid Tissue: Does Sex Matter?

Kiesewetter B, Lukas J, Dolak W, Simonitsch-Klupp I, Mayerhoefer ME, Raderer M.

Oncology. 2016;91(5):243-250. Epub 2016 Aug 23.

PMID:
27548082
34.

HGSNAT has a TATA-less promoter with multiple starts of transcription.

Richtrova E, Mrazova LS, Musalkova D, Luksan O, Stolnaya L, Minks J, Lukas J, Dvorakova L, Jirsa M, Hrebicek M.

Gene. 2016 Oct 30;592(1):36-42. doi: 10.1016/j.gene.2016.07.051. Epub 2016 Jul 22.

PMID:
27452122
35.

53BP1 fosters fidelity of homology-directed DNA repair.

Ochs F, Somyajit K, Altmeyer M, Rask MB, Lukas J, Lukas C.

Nat Struct Mol Biol. 2016 Aug;23(8):714-21. doi: 10.1038/nsmb.3251. Epub 2016 Jun 27.

PMID:
27348077
36.

Treatment by glyphosate-based herbicide alters life history parameters of the rose-grain aphid Metopolophium dirhodum.

Saska P, Skuhrovec J, Lukáš J, Chi H, Tuan SJ, Honěk A.

Sci Rep. 2016 Jun 15;6:27801. doi: 10.1038/srep27801.

37.

Neck Muscles and Content of Carotid Artery as Reference Tissue for Strain Ratio - a Novel Approach to Improve the Diagnostic Performance of Thyroid Elastography?

Kratky J, Vitkova H, Bartakova J, Lukas J, Jiskra J.

Exp Clin Endocrinol Diabetes. 2016 Mar;124(3):192-7. doi: 10.1055/s-0035-1569359. Epub 2016 Mar 23.

PMID:
27008636
38.

Tumor aggressiveness risk factors in the differentiated thyroid carcinoma.

Lukas J, Hitnausova B, Jiskra J, Syrucek M.

Bratisl Lek Listy. 2016;117(2):91-3.

PMID:
26830039
39.

TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity.

Moudry P, Watanabe K, Wolanin KM, Bartkova J, Wassing IE, Watanabe S, Strauss R, Troelsgaard Pedersen R, Oestergaard VH, Lisby M, Andújar-Sánchez M, Maya-Mendoza A, Esashi F, Lukas J, Bartek J.

J Cell Biol. 2016 Feb 1;212(3):281-8. doi: 10.1083/jcb.201507042. Epub 2016 Jan 25.

40.

[Draft of the best medical treatment in patients with low-risk thyroid cancer].

Vlček P, Nováková D, Vejvalka J, Zimák J, Křenek M, Vošmiková K, Smutný S, Bavor P, Astl J, Lukáš J.

Vnitr Lek. 2015 Sep;61(9):769-77. Czech.

PMID:
26465275
41.

A lncRNA to repair DNA.

Lukas J, Altmeyer M.

EMBO Rep. 2015 Nov;16(11):1413-4. doi: 10.15252/embr.201541309. Epub 2015 Sep 29.

42.

Functional and Clinical Consequences of Novel α-Galactosidase A Mutations in Fabry Disease.

Lukas J, Scalia S, Eichler S, Pockrandt AM, Dehn N, Cozma C, Giese AK, Rolfs A.

Hum Mutat. 2016 Jan;37(1):43-51. doi: 10.1002/humu.22910. Epub 2015 Oct 27.

PMID:
26415523
43.

Does Delayed-Time-Point Imaging Improve 18F-FDG-PET in Patients With MALT Lymphoma?: Observations in a Series of 13 Patients.

Mayerhoefer ME, Giraudo C, Senn D, Hartenbach M, Weber M, Rausch I, Kiesewetter B, Herold CJ, Hacker M, Pones M, Simonitsch-Klupp I, Müllauer L, Dolak W, Lukas J, Raderer M.

Clin Nucl Med. 2016 Feb;41(2):101-5. doi: 10.1097/RLU.0000000000001005.

44.

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

Altmeyer M, Neelsen KJ, Teloni F, Pozdnyakova I, Pellegrino S, Grøfte M, Rask MB, Streicher W, Jungmichel S, Nielsen ML, Lukas J.

Nat Commun. 2015 Aug 19;6:8088. doi: 10.1038/ncomms9088.

45.

A novel, highly sensitive and specific biomarker for Niemann-Pick type C1 disease.

Giese AK, Mascher H, Grittner U, Eichler S, Kramp G, Lukas J, te Vruchte D, Al Eisa N, Cortina-Borja M, Porter FD, Platt FM, Rolfs A.

Orphanet J Rare Dis. 2015 Jun 17;10:78. doi: 10.1186/s13023-015-0274-1.

46.

Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining.

Zong D, Callén E, Pegoraro G, Lukas C, Lukas J, Nussenzweig A.

Nucleic Acids Res. 2015 May 26;43(10):4950-61. doi: 10.1093/nar/gkv336. Epub 2015 Apr 27.

47.

Evaluation of Environmental Sampling Methods for Detection of Staphylococcus aureus on Fomites.

Hogan PG, Burnham CA, Singh LN, Patrick CE, Lukas JC, Wang JW, Fraser VJ, Fritz SA.

Ann Public Health Res. 2015 Jan 29;2(1). pii: 1013.

48.

Evaluation of Diffusion-Weighted Magnetic Resonance Imaging for Follow-up and Treatment Response Assessment of Lymphoma: Results of an 18F-FDG-PET/CT-Controlled Prospective Study in 64 Patients.

Mayerhoefer ME, Karanikas G, Kletter K, Prosch H, Kiesewetter B, Skrabs C, Porpaczy E, Weber M, Knogler T, Sillaber C, Jaeger U, Simonitsch-Klupp I, Ubl P, Müllauer L, Dolak W, Lukas J, Raderer M.

Clin Cancer Res. 2015 Jun 1;21(11):2506-13. doi: 10.1158/1078-0432.CCR-14-2454. Epub 2015 Mar 2.

49.

Defects in the retina of Niemann-pick type C 1 mutant mice.

Yan X, Ma L, Hovakimyan M, Lukas J, Wree A, Frank M, Guthoff R, Rolfs A, Witt M, Luo J.

BMC Neurosci. 2014 Nov 29;15:126. doi: 10.1186/s12868-014-0126-2.

50.

A study of methods for evaluating the success of the transition period in early-lactation dairy cows.

Lukas JM, Reneau JK, Wallace RL, De Vries A.

J Dairy Sci. 2015 Jan;98(1):250-62. doi: 10.3168/jds.2014-8522. Epub 2014 Oct 25.

PMID:
25468696

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