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Items: 1 to 50 of 148

1.

Boundary cap neural crest stem cell transplants contribute Mts1/S100A4-expressing cells in the glial scar.

Trolle C, Ivert P, Hoeber J, Rocamonde-Lago I, Vasylovska S, Lukanidin E, Kozlova EN.

Regen Med. 2017 Apr;12(4):339-351. doi: 10.2217/rme-2016-0163. Epub 2017 Jun 16.

PMID:
28621171
2.

The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression.

Atlasi Y, Noori R, Marolin I, Franken P, Brandao J, Biermann K, Collini P, Grigorian M, Lukanidin E, Ambartsumian N, Fodde R.

Eur J Cancer. 2016 Nov;68:114-124. doi: 10.1016/j.ejca.2016.09.012. Epub 2016 Oct 14.

PMID:
27750112
3.

S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance.

Grum-Schwensen B, Klingelhöfer J, Beck M, Bonefeld CM, Hamerlik P, Guldberg P, Grigorian M, Lukanidin E, Ambartsumian N.

BMC Cancer. 2015 Feb 12;15:44. doi: 10.1186/s12885-015-1034-2.

4.

The metastasis-associated protein S100A4 promotes the inflammatory response of mononuclear cells via the TLR4 signalling pathway in rheumatoid arthritis.

Cerezo LA, Remáková M, Tomčik M, Gay S, Neidhart M, Lukanidin E, Pavelka K, Grigorian M, Vencovský J, Šenolt L.

Rheumatology (Oxford). 2014 Aug;53(8):1520-6. doi: 10.1093/rheumatology/keu031. Epub 2014 Mar 18.

5.

A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4.

Hansen MT, Forst B, Cremers N, Quagliata L, Ambartsumian N, Grum-Schwensen B, Klingelhöfer J, Abdul-Al A, Herrmann P, Osterland M, Stein U, Nielsen GH, Scherer PE, Lukanidin E, Sleeman JP, Grigorian M.

Oncogene. 2015 Jan 22;34(4):424-35. doi: 10.1038/onc.2013.568. Epub 2014 Jan 27.

PMID:
24469032
6.

Metastasis-associated protein, S100A4 mediates cardiac fibrosis potentially through the modulation of p53 in cardiac fibroblasts.

Tamaki Y, Iwanaga Y, Niizuma S, Kawashima T, Kato T, Inuzuka Y, Horie T, Morooka H, Takase T, Akahashi Y, Kobuke K, Ono K, Shioi T, Sheikh SP, Ambartsumian N, Lukanidin E, Koshimizu TA, Miyazaki S, Kimura T.

J Mol Cell Cardiol. 2013 Apr;57:72-81. doi: 10.1016/j.yjmcc.2013.01.007. Epub 2013 Jan 23.

PMID:
23352991
7.

Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion.

Klingelhöfer J, Grum-Schwensen B, Beck MK, Knudsen RS, Grigorian M, Lukanidin E, Ambartsumian N.

Neoplasia. 2012 Dec;14(12):1260-8.

8.

The metastasis-promoting S100A4 protein confers neuroprotection in brain injury.

Dmytriyeva O, Pankratova S, Owczarek S, Sonn K, Soroka V, Ridley CM, Marsolais A, Lopez-Hoyos M, Ambartsumian N, Lukanidin E, Bock E, Berezin V, Kiryushko D.

Nat Commun. 2012;3:1197. doi: 10.1038/ncomms2202.

PMID:
23149742
9.

Building the niche: the role of the S100 proteins in metastatic growth.

Lukanidin E, Sleeman JP.

Semin Cancer Biol. 2012 Jun;22(3):216-25. doi: 10.1016/j.semcancer.2012.02.006. Epub 2012 Feb 21. Review.

PMID:
22381352
10.

The metastasis promoting protein S100A4 is increased in idiopathic inflammatory myopathies.

Cerezo LA, Kuncová K, Mann H, Tomcík M, Zámecník J, Lukanidin E, Neidhart M, Gay S, Grigorian M, Vencovsky J, Senolt L.

Rheumatology (Oxford). 2011 Oct;50(10):1766-72. doi: 10.1093/rheumatology/ker218. Epub 2011 Jun 28.

11.

Role of fibulin-5 in metastatic organ colonization.

Møller HD, Ralfkjær U, Cremers N, Frankel M, Pedersen RT, Klingelhöfer J, Yanagisawa H, Grigorian M, Guldberg P, Sleeman J, Lukanidin E, Ambartsumian N.

Mol Cancer Res. 2011 May;9(5):553-63. doi: 10.1158/1541-7786.MCR-11-0093. Epub 2011 Mar 31.

12.

Human mammary fibroblasts stimulate invasion of breast cancer cells in a three-dimensional culture and increase stroma development in mouse xenografts.

Olsen CJ, Moreira J, Lukanidin EM, Ambartsumian NS.

BMC Cancer. 2010 Aug 19;10:444. doi: 10.1186/1471-2407-10-444.

13.

Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice.

Forst B, Hansen MT, Klingelhöfer J, Møller HD, Nielsen GH, Grum-Schwensen B, Ambartsumian N, Lukanidin E, Grigorian M.

PLoS One. 2010 Apr 28;5(4):e10374. doi: 10.1371/journal.pone.0010374.

14.

Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors.

Grum-Schwensen B, Klingelhöfer J, Grigorian M, Almholt K, Nielsen BS, Lukanidin E, Ambartsumian N.

Cancer Res. 2010 Feb 1;70(3):936-47. doi: 10.1158/0008-5472.CAN-09-3220. Epub 2010 Jan 26.

15.

Liprin (beta)1 is highly expressed in lymphatic vasculature and is important for lymphatic vessel integrity.

Norrmén C, Vandevelde W, Ny A, Saharinen P, Gentile M, Haraldsen G, Puolakkainen P, Lukanidin E, Dewerchin M, Alitalo K, Petrova TV.

Blood. 2010 Jan 28;115(4):906-9. doi: 10.1182/blood-2009-03-212274. Epub 2009 Nov 30.

16.

Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein.

Klingelhöfer J, Møller HD, Sumer EU, Berg CH, Poulsen M, Kiryushko D, Soroka V, Ambartsumian N, Grigorian M, Lukanidin EM.

FEBS J. 2009 Oct;276(20):5936-48. doi: 10.1111/j.1742-4658.2009.07274.x. Epub 2009 Sep 9.

17.

Immunogenicity of HLA-A1-restricted peptides derived from S100A4 (metastasin 1) in melanoma patients.

Hofmeister-Mueller V, Vetter-Kauczok CS, Ullrich R, Meder K, Lukanidin E, Broecker EB, Straten Pt, Andersen MH, Schrama D, Becker JC.

Cancer Immunol Immunother. 2009 Aug;58(8):1265-73. doi: 10.1007/s00262-008-0640-0. Epub 2009 Jan 13.

PMID:
19139886
18.

Metastasis-inducing S100A4 protein: implication in non-malignant human pathologies.

Grigorian M, Ambartsumian N, Lukanidin E.

Curr Mol Med. 2008 Sep;8(6):492-6. Review.

PMID:
18781956
19.

Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer.

Cabezón T, Celis JE, Skibshøj I, Klingelhöfer J, Grigorian M, Gromov P, Rank F, Myklebust JH, Maelandsmo GM, Lukanidin E, Ambartsumian N.

Int J Cancer. 2007 Oct 1;121(7):1433-44.

20.

S100A4 is upregulated in injured myocardium and promotes growth and survival of cardiac myocytes.

Schneider M, Kostin S, Strøm CC, Aplin M, Lyngbaek S, Theilade J, Grigorian M, Andersen CB, Lukanidin E, Lerche Hansen J, Sheikh SP.

Cardiovasc Res. 2007 Jul 1;75(1):40-50. Epub 2007 Apr 6.

PMID:
17466960
21.

Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis.

Klingelhöfer J, Senolt L, Baslund B, Nielsen GH, Skibshøj I, Pavelka K, Neidhart M, Gay S, Ambartsumian N, Hansen BS, Petersen J, Lukanidin E, Grigorian M.

Arthritis Rheum. 2007 Mar;56(3):779-89.

22.

Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo.

Takenaga K, Nygren J, Zelenina M, Ohira M, Iuchi T, Lukanidin E, Sjöquist M, Kozlova EN.

Neurobiol Dis. 2007 Mar;25(3):455-63. Epub 2007 Jan 12.

PMID:
17223348
23.

Characterization of E-cadherin-dependent and -independent events in a new model of c-Fos-mediated epithelial-mesenchymal transition.

Mejlvang J, Kriajevska M, Berditchevski F, Bronstein I, Lukanidin EM, Pringle JH, Mellon JK, Tulchinsky EM.

Exp Cell Res. 2007 Jan 15;313(2):380-93. Epub 2006 Oct 26.

PMID:
17141758
24.

S100A4 is expressed at site of invasion in rheumatoid arthritis synovium and modulates production of matrix metalloproteinases.

Senolt L, Grigorian M, Lukanidin E, Simmen B, Michel BA, Pavelka K, Gay RE, Gay S, Neidhart M.

Ann Rheum Dis. 2006 Dec;65(12):1645-8.

25.

Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein.

Kiryushko D, Novitskaya V, Soroka V, Klingelhofer J, Lukanidin E, Berezin V, Bock E.

Mol Cell Biol. 2006 May;26(9):3625-38.

26.

Intracellular calcium-binding protein S100A4 influences injury-induced migration of white matter astrocytes.

Fang Z, Duthoit N, Wicher G, Källskog O, Ambartsumian N, Lukanidin E, Takenaga K, Kozlova EN.

Acta Neuropathol. 2006 Mar;111(3):213-9. Epub 2006 Feb 4.

PMID:
16463066
27.

Sensory neurite outgrowth on white matter astrocytes is influenced by intracellular and extracellular S100A4 protein.

Fang Z, Forslund N, Takenaga K, Lukanidin E, Kozlova EN.

J Neurosci Res. 2006 Mar;83(4):619-26.

PMID:
16435390
28.

S100A4 (Mts1): is there any relation to the pathogenesis of rheumatoid arthritis?

Senolt L, Grigorian M, Lukanidin E, Michel BA, Gay RE, Gay S, Pavelka K, Neidhart M.

Autoimmun Rev. 2006 Feb;5(2):129-31. Epub 2005 Oct 3. Review.

PMID:
16431343
29.

Mts1/S100A4 stimulates human pulmonary artery smooth muscle cell migration through multiple signaling pathways.

Spiekerkoetter E, Lawrie A, Merklinger S, Ambartsumian N, Lukanidin E, Schmidt AM, Rabinovitch M.

Chest. 2005 Dec;128(6 Suppl):577S. No abstract available.

PMID:
16373840
30.

Immediate and delayed effects of E-cadherin inhibition on gene regulation and cell motility in human epidermoid carcinoma cells.

Andersen H, Mejlvang J, Mahmood S, Gromova I, Gromov P, Lukanidin E, Kriajevska M, Mellon JK, Tulchinsky E.

Mol Cell Biol. 2005 Oct;25(20):9138-50.

31.

Genetically modified mouse models to study the role of metastasis-promoting S100A4(mts1) protein in metastatic mammary cancer.

Ambartsumian N, Grigorian M, Lukanidin E.

J Dairy Res. 2005;72 Spec No:27-33. Review.

PMID:
16180718
32.

Increased fibulin-5 and elastin in S100A4/Mts1 mice with pulmonary hypertension.

Merklinger SL, Wagner RA, Spiekerkoetter E, Hinek A, Knutsen RH, Kabir MG, Desai K, Hacker S, Wang L, Cann GM, Ambartsumian NS, Lukanidin E, Bernstein D, Husain M, Mecham RP, Starcher B, Yanagisawa H, Rabinovitch M.

Circ Res. 2005 Sep 16;97(6):596-604. Epub 2005 Aug 18.

PMID:
16109920
33.

Proteolytic processing converts the repelling signal Sema3E into an inducer of invasive growth and lung metastasis.

Christensen C, Ambartsumian N, Gilestro G, Thomsen B, Comoglio P, Tamagnone L, Guldberg P, Lukanidin E.

Cancer Res. 2005 Jul 15;65(14):6167-77.

34.

Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease.

Lawrie A, Spiekerkoetter E, Martinez EC, Ambartsumian N, Sheward WJ, MacLean MR, Harmar AJ, Schmidt AM, Lukanidin E, Rabinovitch M.

Circ Res. 2005 Aug 5;97(3):227-35. Epub 2005 Jul 7.

PMID:
16002749
35.

The metastasis associated protein S100A4: role in tumour progression and metastasis.

Helfman DM, Kim EJ, Lukanidin E, Grigorian M.

Br J Cancer. 2005 Jun 6;92(11):1955-8. Review.

36.

Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene.

Grum-Schwensen B, Klingelhofer J, Berg CH, El-Naaman C, Grigorian M, Lukanidin E, Ambartsumian N.

Cancer Res. 2005 May 1;65(9):3772-80.

37.

The Mts1/S100A4 protein is a neuroprotectant.

Pedersen MV, Køhler LB, Grigorian M, Novitskaya V, Bock E, Lukanidin E, Berezin V.

J Neurosci Res. 2004 Sep 15;77(6):777-86.

PMID:
15334597
38.

Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity.

Schmidt-Hansen B, Ornås D, Grigorian M, Klingelhöfer J, Tulchinsky E, Lukanidin E, Ambartsumian N.

Oncogene. 2004 Jul 15;23(32):5487-95.

PMID:
15122322
39.

Cancer predisposition in mice deficient for the metastasis-associated Mts1(S100A4) gene.

EL Naaman C, Grum-Schwensen B, Mansouri A, Grigorian M, Santoni-Rugiu E, Hansen T, Kriajevska M, Schafer BW, Heizmann CW, Lukanidin E, Ambartsumian N.

Oncogene. 2004 Apr 29;23(20):3670-80.

PMID:
15116098
40.

Functional significance of metastasis-inducing S100A4(Mts1) in tumor-stroma interplay.

Schmidt-Hansen B, Klingelhöfer J, Grum-Schwensen B, Christensen A, Andresen S, Kruse C, Hansen T, Ambartsumian N, Lukanidin E, Grigorian M.

J Biol Chem. 2004 Jun 4;279(23):24498-504. Epub 2004 Mar 26.

41.

S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathy.

Greenway S, van Suylen RJ, Du Marchie Sarvaas G, Kwan E, Ambartsumian N, Lukanidin E, Rabinovitch M.

Am J Pathol. 2004 Jan;164(1):253-62.

42.

[Activator of metastasis in cancer cells, Mst1/S100A4 protein binds to tumor suppressor protein p53].

Grigorian M, Lukanidin E.

Genetika. 2003 Jul;39(7):900-8. Russian.

PMID:
12942774
43.

Role of the Fos family members, c-Fos, Fra-1 and Fra-2, in the regulation of cell motility.

Tkach V, Tulchinsky E, Lukanidin E, Vinson C, Bock E, Berezin V.

Oncogene. 2003 Aug 7;22(32):5045-54.

PMID:
12902987
44.

Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research.

Celis JE, Gromov P, Gromova I, Moreira JM, Cabezón T, Ambartsumian N, Grigorian M, Lukanidin E, Thor Straten P, Guldberg P, Bartkova J, Bartek J, Lukas J, Lukas C, Lykkesfeldt A, Jäättelä M, Roepstorff P, Bolund L, Ørntoft T, Brünner N, Overgaard J, Sandelin K, Blichert-Toft M, Mouridsen H, Rank FE.

Mol Cell Proteomics. 2003 Jun;2(6):369-77. Epub 2003 Jun 25.

45.

Structure of the human S100A12-copper complex: implications for host-parasite defence.

Moroz OV, Antson AA, Grist SJ, Maitland NJ, Dodson GG, Wilson KS, Lukanidin E, Bronstein IB.

Acta Crystallogr D Biol Crystallogr. 2003 May;59(Pt 5):859-67. Epub 2003 Apr 25.

PMID:
12777802
46.

Multiple structural states of S100A12: A key to its functional diversity.

Moroz OV, Dodson GG, Wilson KS, Lukanidin E, Bronstein IB.

Microsc Res Tech. 2003 Apr 15;60(6):581-92. Review.

PMID:
12645006
47.

The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials.

Andersen H, Mahmood S, Tkach V, Cohn M, Kustikova O, Grigorian M, Berezin V, Bock E, Lukanidin E, Tulchinsky E.

Oncogene. 2002 Jul 18;21(31):4843-8.

48.

Possible co-regulation of genes associated with enhanced progression of mammary adenocarcinomas.

Neumark E, Cohn MA, Lukanidin E, Witz IP, Ben-Baruch A.

Immunol Lett. 2002 Jun 3;82(1-2):111-21.

PMID:
12008042
49.

Mts1 protein expression in the central nervous system after injury.

Kozlova EN, Lukanidin E.

Glia. 2002 Mar 15;37(4):337-48.

PMID:
11870873
50.

The structure of S100A12 in a hexameric form and its proposed role in receptor signalling.

Moroz OV, Antson AA, Dodson EJ, Burrell HJ, Grist SJ, Lloyd RM, Maitland NJ, Dodson GG, Wilson KS, Lukanidin E, Bronstein IB.

Acta Crystallogr D Biol Crystallogr. 2002 Mar;58(Pt 3):407-13. Epub 2002 Feb 21.

PMID:
11856825

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