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Items: 24

1.

Smoking is Associated to DNA Methylation in Atherosclerotic Carotid Lesions.

Siemelink MA, van der Laan SW, Haitjema S, van Koeverden ID, Schaap J, Wesseling M, de Jager SCA, Mokry M, van Iterson M, Dekkers KF, Luijk R, Foroughi Asl H, Michoel T, Björkegren JLM, Aavik E, Ylä-Herttuala S, de Borst GJ, Asselbergs FW, El Azzouzi H, den Ruijter HM, Heijmans BT, Pasterkamp G.

Circ Genom Precis Med. 2018 Sep;11(9):e002030. doi: 10.1161/CIRCGEN.117.002030.

PMID:
30354327
2.

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation.

Luijk R, Wu H, Ward-Caviness CK, Hannon E, Carnero-Montoro E, Min JL, Mandaviya P, Müller-Nurasyid M, Mei H, van der Maarel SM; BIOS Consortium, Relton C, Mill J, Waldenberger M, Bell JT, Jansen R, Zhernakova A, Franke L, 't Hoen PAC, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, van Meurs J, Daxinger L, Slagboom PE, van Zwet EW, Heijmans BT.

Nat Commun. 2018 Sep 14;9(1):3738. doi: 10.1038/s41467-018-05714-3.

3.

Genome-wide identification of directed gene networks using large-scale population genomics data.

Luijk R, Dekkers KF, van Iterson M, Arindrarto W, Claringbould A, Hop P, Boomsma DI, van Duijn CM, van Greevenbroek MMJ, Veldink JH, Wijmenga C, Franke L, 't Hoen PAC, Jansen R, van Meurs J, Mei H, Slagboom PE, Heijmans BT, van Zwet EW; BIOS (Biobank-based Integrative Omics Study) Consortium.

Nat Commun. 2018 Aug 6;9(1):3097. doi: 10.1038/s41467-018-05452-6.

4.

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood.

Tobi EW, Slieker RC, Luijk R, Dekkers KF, Stein AD, Xu KM; Biobank-based Integrative Omics Studies Consortium, Slagboom PE, van Zwet EW, Lumey LH, Heijmans BT.

Sci Adv. 2018 Jan 31;4(1):eaao4364. doi: 10.1126/sciadv.aao4364. eCollection 2018 Jan.

5.

Disease variants alter transcription factor levels and methylation of their binding sites.

Bonder MJ, Luijk R, Zhernakova DV, Moed M, Deelen P, Vermaat M, van Iterson M, van Dijk F, van Galen M, Bot J, Slieker RC, Jhamai PM, Verbiest M, Suchiman HE, Verkerk M, van der Breggen R, van Rooij J, Lakenberg N, Arindrarto W, Kielbasa SM, Jonkers I, van 't Hof P, Nooren I, Beekman M, Deelen J, van Heemst D, Zhernakova A, Tigchelaar EF, Swertz MA, Hofman A, Uitterlinden AG, Pool R, van Dongen J, Hottenga JJ, Stehouwer CD, van der Kallen CJ, Schalkwijk CG, van den Berg LH, van Zwet EW, Mei H, Li Y, Lemire M, Hudson TJ; BIOS Consortium, Slagboom PE, Wijmenga C, Veldink JH, van Greevenbroek MM, van Duijn CM, Boomsma DI, Isaacs A, Jansen R, van Meurs JB, 't Hoen PA, Franke L, Heijmans BT.

Nat Genet. 2017 Jan;49(1):131-138. doi: 10.1038/ng.3721. Epub 2016 Dec 5.

PMID:
27918535
6.

Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms.

Slieker RC, van Iterson M, Luijk R, Beekman M, Zhernakova DV, Moed MH, Mei H, van Galen M, Deelen P, Bonder MJ, Zhernakova A, Uitterlinden AG, Tigchelaar EF, Stehouwer CD, Schalkwijk CG, van der Kallen CJ, Hofman A, van Heemst D, de Geus EJ, van Dongen J, Deelen J, van den Berg LH, van Meurs J, Jansen R, 't Hoen PA, Franke L, Wijmenga C, Veldink JH, Swertz MA, van Greevenbroek MM, van Duijn CM, Boomsma DI; BIOS consortium, Slagboom PE, Heijmans BT.

Genome Biol. 2016 Sep 22;17(1):191.

7.

[Cost-effectiveness in Dutch mental health care: future because of ROM?].

van Agthoven M, van der Kolk A, Knegtering H, Delespaul PA, Arends J, Jeurissen PP, Krabbe PF, Huijsman R, Luijk R, De Beurs E, Hakkaart-Van Roijen L, Bruggeman R.

Tijdschr Psychiatr. 2015;57(9):672-9. Dutch.

8.

An alternative approach to multiple testing for methylation QTL mapping reduces the proportion of falsely identified CpGs.

Luijk R, Goeman JJ, Slagboom EP, Heijmans BT, van Zwet EW.

Bioinformatics. 2015 Feb 1;31(3):340-5. doi: 10.1093/bioinformatics/btu654. Epub 2014 Oct 4.

PMID:
25282645
9.

Differential methylation within the major histocompatibility complex region in rheumatoid arthritis: a replication study.

van Steenbergen HW, Luijk R, Shoemaker R, Heijmans BT, Huizinga TW, van der Helm-van Mil AH.

Rheumatology (Oxford). 2014 Dec;53(12):2317-8. doi: 10.1093/rheumatology/keu380. Epub 2014 Sep 30. No abstract available.

PMID:
25273994
10.

MethylAid: visual and interactive quality control of large Illumina 450k datasets.

van Iterson M, Tobi EW, Slieker RC, den Hollander W, Luijk R, Slagboom PE, Heijmans BT.

Bioinformatics. 2014 Dec 1;30(23):3435-7. doi: 10.1093/bioinformatics/btu566. Epub 2014 Aug 21.

PMID:
25147358
11.

[ROM and the position of the health insurance companies].

Laane R, Luijk R.

Tijdschr Psychiatr. 2012;54(2):135-9. Dutch.

12.

The molecular basis of the folate-sensitive fragile site FRA11A at 11q13.

Debacker K, Winnepenninckx B, Longman C, Colgan J, Tolmie J, Murray R, van Luijk R, Scheers S, Fitzpatrick D, Kooy F.

Cytogenet Genome Res. 2007;119(1-2):9-14. Epub 2007 Dec 14.

PMID:
18160775
13.

A de novo subtelomeric monosomy 11q (11q24.2-qter) and trisomy 20q (20q13.3-qter) in a girl with findings compatible with Jacobsen syndrome: case report and review.

Courtens W, Wauters J, Wojciechowski M, Reyniers E, Scheers S, van Luijk R, Rooms L, Kooy F, Wuyts W.

Clin Dysmorphol. 2007 Oct;16(4):231-9. Review.

PMID:
17786114
14.

FRA18C: a new aphidicolin-inducible fragile site on chromosome 18q22, possibly associated with in vivo chromosome breakage.

Debacker K, Winnepenninckx B, Ben-Porat N, FitzPatrick D, Van Luijk R, Scheers S, Kerem B, Frank Kooy R.

J Med Genet. 2007 May;44(5):347-52.

15.

Microdeletions involving the SCN1A gene may be common in SCN1A-mutation-negative SMEI patients.

Suls A, Claeys KG, Goossens D, Harding B, Van Luijk R, Scheers S, Deprez L, Audenaert D, Van Dyck T, Beeckmans S, Smouts I, Ceulemans B, Lagae L, Buyse G, Barisic N, Misson JP, Wauters J, Del-Favero J, De Jonghe P, Claes LR.

Hum Mutat. 2006 Sep;27(9):914-20.

PMID:
16865694
16.

TBP as a candidate gene for mental retardation in patients with subtelomeric 6q deletions.

Rooms L, Reyniers E, Scheers S, van Luijk R, Wauters J, Van Aerschot L, Callaerts-Vegh Z, D'Hooge R, Mengus G, Davidson I, Courtens W, Kooy RF.

Eur J Hum Genet. 2006 Oct;14(10):1090-6. Epub 2006 Jun 14.

17.

A de novo subterminal trisomy 10p and monosomy 18q in a girl with MCA/MR: case report and review.

Courtens W, Wuyts W, Scheers S, Van Luijk R, Reyniers E, Rooms L, Ceulemans B, Kooy F, Wauters J.

Eur J Med Genet. 2006 Sep-Oct;49(5):402-13. Epub 2006 Jan 30. Review.

PMID:
16488200
18.

Multiplex ligation-dependent probe amplification to detect subtelomeric rearrangements in routine diagnostics.

Rooms L, Reyniers E, Wuyts W, Storm K, van Luijk R, Scheers S, Wauters J, van den Ende J, Biervliet M, Eyskens F, van Goethem G, Laridon A, Ceulemans B, Courtens W, Kooy RF.

Clin Genet. 2006 Jan;69(1):58-64.

PMID:
16451137
19.

Clinical report of a pure subtelomeric 1qter deletion in a boy with mental retardation and multiple anomalies adds further evidence for a specific phenotype.

van Bever Y, Rooms L, Laridon A, Reyniers E, van Luijk R, Scheers S, Wauters J, Kooy RF.

Am J Med Genet A. 2005 May 15;135(1):91-5. Review.

PMID:
15822126
20.

Screening for subtelomeric rearrangements using genetic markers in 70 patients with unexplained mental retardation.

Rooms L, Reyniers E, van Luijk R, Scheers S, Wauters J, Kooy RF.

Ann Genet. 2004 Jan-Mar;47(1):53-9.

PMID:
15050874
21.

Subtelomeric deletions detected in patients with idiopathic mental retardation using multiplex ligation-dependent probe amplification (MLPA).

Rooms L, Reyniers E, van Luijk R, Scheers S, Wauters J, Ceulemans B, Van Den Ende J, Van Bever Y, Kooy RF.

Hum Mutat. 2004 Jan;23(1):17-21.

PMID:
14695528
22.

Deletions at chromosome regions 7q11.23 and 7q36 in a patient with Williams syndrome.

Wouters CH, Meijers-Heijboer HJ, Eussen BJ, van der Heide AA, van Luijk RB, van Drunen E, Beverloo BB, Visscher F, Van Hemel JO.

Am J Med Genet. 2001 Aug 15;102(3):261-5.

PMID:
11484204
23.

Mechanism of formation of polychlorinated dibenzo-p-dioxins and dibenzofurans in the catalyzed combustion of carbon.

Luijk R, Akkerman DM, Slot P, Olie K, Kapteijn F.

Environ Sci Technol. 1994 Feb 1;28(2):312-21. doi: 10.1021/es00051a019. No abstract available.

PMID:
22176178
24.

Descriptors for isomer resolution of (bio-) distribution of chlorinated aromatic compounds.

Govers HA, Luijk R, Evers EH.

Sci Total Environ. 1991 Dec;109-110:105-19.

PMID:
1815348

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