Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 77

1.

Prenatal Immune Challenge in Mice Leads to Partly Sex-Dependent Behavioral, Microglial, and Molecular Abnormalities Associated with Schizophrenia.

Hui CW, St-Pierre A, El Hajj H, Remy Y, Hébert SS, Luheshi GN, Srivastava LK, Tremblay MÈ.

Front Mol Neurosci. 2018 Feb 8;11:13. doi: 10.3389/fnmol.2018.00013. eCollection 2018.

2.

Plasticity of the epigenome during early-life stress.

Burns SB, Szyszkowicz JK, Luheshi GN, Lutz PE, Turecki G.

Semin Cell Dev Biol. 2018 May;77:115-132. doi: 10.1016/j.semcdb.2017.09.033. Epub 2017 Oct 16. Review.

PMID:
29017800
3.

Prenatal infection leads to ASD-like behavior and altered synaptic pruning in the mouse offspring.

Fernández de Cossío L, Guzmán A, van der Veldt S, Luheshi GN.

Brain Behav Immun. 2017 Jul;63:88-98. doi: 10.1016/j.bbi.2016.09.028. Epub 2016 Sep 30.

PMID:
27697456
4.

Role of brain transmigrating neutrophils in depression-like behavior during systemic infection.

Aguilar-Valles A, Kim J, Jung S, Woodside B, Luheshi GN.

Mol Psychiatry. 2015 Mar;20(3):413-4. doi: 10.1038/mp.2014.173. Epub 2015 Feb 3. No abstract available.

PMID:
25644382
5.

Obesity, adipokines and neuroinflammation.

Aguilar-Valles A, Inoue W, Rummel C, Luheshi GN.

Neuropharmacology. 2015 Sep;96(Pt A):124-34. doi: 10.1016/j.neuropharm.2014.12.023. Epub 2015 Jan 10. Review.

PMID:
25582291
6.

Leptin modulates the late fever response to LPS in diet-induced obese animals.

Pohl J, Woodside B, Luheshi GN.

Brain Behav Immun. 2014 Nov;42:41-7. doi: 10.1016/j.bbi.2014.07.017. Epub 2014 Aug 7.

PMID:
25108212
7.

Leptin is involved in age-dependent changes in response to systemic inflammation in the rat.

Koenig S, Luheshi GN, Wenz T, Gerstberger R, Roth J, Rummel C.

Brain Behav Immun. 2014 Feb;36:128-38.

PMID:
24513873
8.

Role of brain transmigrating neutrophils in depression-like behavior during systemic infection.

Aguilar-Valles A, Kim J, Jung S, Woodside B, Luheshi GN.

Mol Psychiatry. 2014 May;19(5):599-606. doi: 10.1038/mp.2013.137. Epub 2013 Oct 15. Erratum in: Mol Psychiatry. 2015 Mar;20(3):413-4. Mol Psychiatry. 2014 May;19(5):633. Aguliar-Valles, A [corrected to Aguilar-Valles].

PMID:
24126927
9.

The effects of dietary saturated fat on basal hypothalamic neuroinflammation in rats.

Maric T, Woodside B, Luheshi GN.

Brain Behav Immun. 2014 Feb;36:35-45. doi: 10.1016/j.bbi.2013.09.011. Epub 2013 Sep 25.

PMID:
24075847
10.

Diet-induced weight gain produces a graded increase in behavioral responses to an acute immune challenge.

Pohl J, Sheppard M, Luheshi GN, Woodside B.

Brain Behav Immun. 2014 Jan;35:43-50. doi: 10.1016/j.bbi.2013.09.002. Epub 2013 Sep 8.

PMID:
24026015
11.

Time-dependent effects of localized inflammation on peripheral clock gene expression in rats.

Westfall S, Aguilar-Valles A, Mongrain V, Luheshi GN, Cermakian N.

PLoS One. 2013;8(3):e59808. doi: 10.1371/journal.pone.0059808. Epub 2013 Mar 20.

12.

Interleukin-10 modulates the synthesis of inflammatory mediators in the sensory circumventricular organs: implications for the regulation of fever and sickness behaviors.

Harden LM, Rummel C, Luheshi GN, Poole S, Gerstberger R, Roth J.

J Neuroinflammation. 2013 Feb 6;10:22. doi: 10.1186/1742-2094-10-22.

13.

Effect of obesity on the acute inflammatory response in pregnant and cycling female rats.

Pohl J, Luheshi GN, Woodside B.

J Neuroendocrinol. 2013 May;25(5):433-45. doi: 10.1111/jne.12023.

PMID:
23331909
14.

Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation.

Aguilar-Valles A, Jung S, Poole S, Flores C, Luheshi GN.

Psychoneuroendocrinology. 2012 Jul;37(7):956-69. doi: 10.1016/j.psyneuen.2011.11.003. Epub 2011 Nov 30.

PMID:
22133515
15.

Circulating IL-6 contributes to peripheral LPS-induced mPGES-1 expression in the rat brain.

Rummel C, Matsumura K, Luheshi GN.

Brain Res Bull. 2011 Nov 25;86(5-6):319-25. doi: 10.1016/j.brainresbull.2011.09.006. Epub 2011 Sep 16.

PMID:
21945087
16.

Effects of endogenous glucocorticoid secretion on the interleukin-6 response to bacterial endotoxin in pregnant and non-pregnant rats.

Cui K, Luheshi GN, Boksa P.

J Endocrinol. 2011 Apr;209(1):95-103. doi: 10.1530/JOE-10-0436. Epub 2011 Jan 17.

17.

Spatiotemporal nuclear factor interleukin-6 expression in the rat brain during lipopolysaccharide-induced fever is linked to sustained hypothalamic inflammatory target gene induction.

Damm J, Luheshi GN, Gerstberger R, Roth J, Rummel C.

J Comp Neurol. 2011 Feb 15;519(3):480-505. doi: 10.1002/cne.22529.

PMID:
21192080
18.

Acute starvation alters lipopolysaccharide-induced fever in leptin-dependent and -independent mechanisms in rats.

Inoue W, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2010 Dec;299(6):R1709-19. doi: 10.1152/ajpregu.00567.2010. Epub 2010 Oct 13.

19.

Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy.

Aguilar-Valles A, Luheshi GN.

Psychoneuroendocrinology. 2011 Jun;36(5):634-48. doi: 10.1016/j.psyneuen.2010.09.006. Epub 2010 Oct 12.

PMID:
20934257
20.

Prenatal inflammation-induced hypoferremia alters dopamine function in the adult offspring in rat: relevance for schizophrenia.

Aguilar-Valles A, Flores C, Luheshi GN.

PLoS One. 2010 Jun 4;5(6):e10967. doi: 10.1371/journal.pone.0010967.

21.

Leptin modulates cell morphology and cytokine release in microglia.

Lafrance V, Inoue W, Kan B, Luheshi GN.

Brain Behav Immun. 2010 Mar;24(3):358-65. doi: 10.1016/j.bbi.2009.11.003. Epub 2009 Nov 14.

PMID:
19922787
22.

Changes in hypothalamically mediated acute-phase inflammatory responses to lipopolysaccharide in diet-induced obese rats.

Pohl J, Woodside B, Luheshi GN.

Endocrinology. 2009 Nov;150(11):4901-10. doi: 10.1210/en.2009-0526. Epub 2009 Sep 24.

PMID:
19797120
23.

Leptin regulates leukocyte recruitment into the brain following systemic LPS-induced inflammation.

Rummel C, Inoue W, Poole S, Luheshi GN.

Mol Psychiatry. 2010 May;15(5):523-34. doi: 10.1038/mp.2009.98. Epub 2009 Sep 22.

PMID:
19773811
24.

Effects of prenatal immune activation on hippocampal neurogenesis in the rat.

Cui K, Ashdown H, Luheshi GN, Boksa P.

Schizophr Res. 2009 Sep;113(2-3):288-97. doi: 10.1016/j.schres.2009.05.003. Epub 2009 May 22.

PMID:
19464151
25.

Central nervous action of interleukin-1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide.

Konsman JP, Veeneman J, Combe C, Poole S, Luheshi GN, Dantzer R.

Eur J Neurosci. 2008 Dec;28(12):2499-510. doi: 10.1111/j.1460-9568.2008.06549.x.

PMID:
19087175
26.

Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice.

Rummel C, Inoue W, Sachot C, Poole S, Hübschle T, Luheshi GN.

J Comp Neurol. 2008 Nov 20;511(3):373-95. doi: 10.1002/cne.21850.

PMID:
18803240
27.

Maternal infection and fever during late gestation are associated with altered synaptic transmission in the hippocampus of juvenile offspring rats.

Lowe GC, Luheshi GN, Williams S.

Am J Physiol Regul Integr Comp Physiol. 2008 Nov;295(5):R1563-71. doi: 10.1152/ajpregu.90350.2008. Epub 2008 Aug 27.

28.

Acute brain cytokine responses after global birth hypoxia in the rat.

Ashdown H, Joita S, Luheshi GN, Boksa P.

J Neurosci Res. 2008 Nov 15;86(15):3401-9. doi: 10.1002/jnr.21785.

PMID:
18627031
29.

Immune-to-brain signaling and central prostaglandin E2 synthesis in fasted rats with altered lipopolysaccharide-induced fever.

Inoue W, Somay G, Poole S, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R133-43. doi: 10.1152/ajpregu.90335.2008. Epub 2008 May 14.

30.

Attenuated fever in rats during late pregnancy is linked to suppressed interleukin-6 production after localized inflammation with turpentine.

Aguilar-Valles A, Poole S, Mistry Y, Williams S, Luheshi GN.

J Physiol. 2007 Aug 15;583(Pt 1):391-403. Epub 2007 Jun 7.

31.

Effects of prenatal infection on prepulse inhibition in the rat depend on the nature of the infectious agent and the stage of pregnancy.

Fortier ME, Luheshi GN, Boksa P.

Behav Brain Res. 2007 Aug 6;181(2):270-7. Epub 2007 Apr 27.

PMID:
17553574
32.

Is programming of weight regulation immune to neonatal inflammation?

Luheshi GN, Rummel C.

Am J Physiol Regul Integr Comp Physiol. 2007 Aug;293(2):R578-80. Epub 2007 May 30. Review. No abstract available.

33.

Leptin induces interleukin-1beta release from rat microglial cells through a caspase 1 independent mechanism.

Pinteaux E, Inoue W, Schmidt L, Molina-Holgado F, Rothwell NJ, Luheshi GN.

J Neurochem. 2007 Aug;102(3):826-33. Epub 2007 Apr 10.

34.

The role of the vagus nerve in mediating the long-term anorectic effects of leptin.

Sachot C, Rummel C, Bristow AF, Luheshi GN.

J Neuroendocrinol. 2007 Apr;19(4):250-61.

PMID:
17355316
35.

Interleukin-1 receptor antagonist as a modulator of gender differences in the febrile response to lipopolysaccharide in rats.

Ashdown H, Poole S, Boksa P, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2007 Apr;292(4):R1667-74. Epub 2006 Nov 30.

36.

Leptin induces cyclooxygenase-2 via an interaction with interleukin-1beta in the rat brain.

Inoue W, Poole S, Bristow AF, Luheshi GN.

Eur J Neurosci. 2006 Oct;24(8):2233-45.

PMID:
17074047
37.

Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain.

Rummel C, Sachot C, Poole S, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2006 Nov;291(5):R1316-26. Epub 2006 Jun 29.

38.

The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia.

Ashdown H, Dumont Y, Ng M, Poole S, Boksa P, Luheshi GN.

Mol Psychiatry. 2006 Jan;11(1):47-55.

PMID:
16189509
40.

Circulating leptin mediates lipopolysaccharide-induced anorexia and fever in rats.

Sachot C, Poole S, Luheshi GN.

J Physiol. 2004 Nov 15;561(Pt 1):263-72. Epub 2004 Sep 23.

41.

The viral mimic, polyinosinic:polycytidylic acid, induces fever in rats via an interleukin-1-dependent mechanism.

Fortier ME, Kent S, Ashdown H, Poole S, Boksa P, Luheshi GN.

Am J Physiol Regul Integr Comp Physiol. 2004 Oct;287(4):R759-66. Epub 2004 Jun 17.

42.
43.

Identification of a truncated IL-18R beta mRNA: a putative regulator of IL-18 expressed in rat brain.

Andre R, Wheeler RD, Collins PD, Luheshi GN, Pickering-Brown S, Kimber I, Rothwell NJ, Pinteaux E.

J Neuroimmunol. 2003 Dec;145(1-2):40-5.

PMID:
14644029
44.

Up-regulation of IL-18BP, but not IL-18 mRNA in rat liver by LPS.

Wheeler RD, Young EA, Rothwell NJ, Hall MD, Luheshi GN.

Cytokine. 2003 Feb 21;21(4):161-6.

PMID:
12788303
45.

Interleukin-18 induces expression and release of cytokines from murine glial cells: interactions with interleukin-1 beta.

Wheeler RD, Brough D, Le Feuvre RA, Takeda K, Iwakura Y, Luheshi GN, Rothwell NJ.

J Neurochem. 2003 Jun;85(6):1412-20.

46.

No role for interleukin-18 in acute murine stroke-induced brain injury.

Wheeler RD, Boutin H, Touzani O, Luheshi GN, Takeda K, Rothwell NJ.

J Cereb Blood Flow Metab. 2003 May;23(5):531-5.

PMID:
12771567
47.

Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells.

Pinteaux E, Parker LC, Rothwell NJ, Luheshi GN.

J Neurochem. 2002 Nov;83(4):754-63.

48.

IL-1 beta signalling in glial cells in wildtype and IL-1RI deficient mice.

Parker LC, Luheshi GN, Rothwell NJ, Pinteaux E.

Br J Pharmacol. 2002 May;136(2):312-20.

49.

Vagotomy attenuates the behavioural but not the pyrogenic effects of interleukin-1 in rats.

Luheshi GN, Bluthé RM, Rushforth D, Mulcahy N, Konsman JP, Goldbach M, Dantzer R.

Auton Neurosci. 2000 Dec 20;85(1-3):127-32.

PMID:
11189019
50.

Role of endogenous interleukin-1 receptor antagonist in regulating fever induced by localised inflammation in the rat.

Cartmell T, Luheshi GN, Hopkins SJ, Rothwell NJ, Poole S.

J Physiol. 2001 Feb 15;531(Pt 1):171-80.

Supplemental Content

Loading ...
Support Center