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Items: 1 to 50 of 87

1.

A prospective study on serum Cytokeratin (CK)-18 and CK18 fragments as biomarkers of acute hepato-intestinal GVHD.

Sauer S, Hüsing J, Hajda J, Neumann F, Radujkovic A, Ho AD, Dreger P, Luft T.

Leukemia. 2018 Jun 27. doi: 10.1038/s41375-018-0183-0. [Epub ahead of print]

PMID:
29950693
2.

Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.

Pellagatti A, Armstrong RN, Steeples V, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Broxholme J, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Hennrich ML, Gavin AC, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith S, Boultwood J.

Blood. 2018 Jun 21. pii: blood-2018-04-843771. doi: 10.1182/blood-2018-04-843771. [Epub ahead of print]

PMID:
29930011
3.

CD7 is expressed on a subset of normal CD34-positive myeloid precursors.

Kriegsmann K, Löffler H, Eckstein V, Schulz R, Kräker S, Braun U, Luft T, Hegenbart U, Schönland S, Dreger P, Krämer A, Ho AD, Müller-Tidow C, Hundemer M.

Eur J Haematol. 2018 May 24. doi: 10.1111/ejh.13100. [Epub ahead of print]

PMID:
29797671
4.

Safety and efficacy of the CD95-ligand inhibitor asunercept in transfusion-dependent patients with low and intermediate risk MDS.

Boch T, Luft T, Metzgeroth G, Mossner M, Jann JC, Nowak D, Meir F, Schumann C, Klemmer J, Brendel S, Fricke H, Kunz C, Weiß C, Hofmann WK, Nolte F.

Leuk Res. 2018 May;68:62-69. doi: 10.1016/j.leukres.2018.03.007. Epub 2018 Mar 10.

PMID:
29549809
5.

The impact of stem cell transplantation on the natural course of peripheral T-cell lymphoma: a real-world experience.

Rohlfing S, Dietrich S, Witzens-Harig M, Hegenbart U, Schönland S, Luft T, Ho AD, Dreger P.

Ann Hematol. 2018 Jul;97(7):1241-1250. doi: 10.1007/s00277-018-3288-7. Epub 2018 Mar 16.

PMID:
29549411
6.

Single Nucleotide Polymorphisms in CD40L Predict Endothelial Complications and Mortality After Allogeneic Stem-Cell Transplantation.

Rachakonda SP, Dai H, Penack O, Blau O, Blau IW, Radujkovic A, Müller-Tidow C, Kumar R, Dreger P, Luft T.

J Clin Oncol. 2018 Mar 10;36(8):789-800. doi: 10.1200/JCO.2017.76.4662. Epub 2018 Jan 25.

PMID:
29369699
7.

Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.

Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, Gupta D, Bock F, Wang H, Shaikh H, Kähne T, Reinhold D, Bank U, Zenclussen AC, Niemz J, Schnöder TM, Brunner-Weinzierl M, Fischer T, Kalinski T, Schraven B, Luft T, Huehn J, Naumann M, Heidel FH, Isermann B.

Nat Commun. 2017 Aug 21;8(1):311. doi: 10.1038/s41467-017-00169-4.

8.

Pretransplant Vitamin D Deficiency Is Associated With Higher Relapse Rates in Patients Allografted for Myeloid Malignancies.

Radujkovic A, Kordelas L, Krzykalla J, Beelen DW, Benner A, Lehners N, Schmidt K, Dreger P, Luft T.

J Clin Oncol. 2017 Sep 20;35(27):3143-3152. doi: 10.1200/JCO.2017.73.0085. Epub 2017 Aug 3.

PMID:
28771378
9.

EASIX in patients with acute graft-versus-host disease: a retrospective cohort analysis.

Luft T, Benner A, Jodele S, Dandoy CE, Storb R, Gooley T, Sandmaier BM, Becker N, Radujkovic A, Dreger P, Penack O.

Lancet Haematol. 2017 Sep;4(9):e414-e423. doi: 10.1016/S2352-3026(17)30108-4. Epub 2017 Jul 18.

PMID:
28733186
10.

Transplant-associated thrombotic microangiopathy is an endothelial complication associated with refractoriness of acute GvHD.

Zeisbrich M, Becker N, Benner A, Radujkovic A, Schmitt K, Beimler J, Ho AD, Zeier M, Dreger P, Luft T.

Bone Marrow Transplant. 2017 Oct;52(10):1399-1405. doi: 10.1038/bmt.2017.119. Epub 2017 Jun 26.

PMID:
28650448
11.

GvL effects in T-prolymphocytic leukemia: evidence from MRD kinetics and TCR repertoire analyses.

Sellner L, Brüggemann M, Schlitt M, Knecht H, Herrmann D, Reigl T, Krejci A, Bystry V, Darzentas N, Rieger M, Dietrich S, Luft T, Ho AD, Kneba M, Dreger P.

Bone Marrow Transplant. 2017 Apr;52(4):656. doi: 10.1038/bmt.2017.12. No abstract available.

PMID:
28377595
12.

GvL effects in T-prolymphocytic leukemia: evidence from MRD kinetics and TCR repertoire analyses.

Sellner L, Brüggemann M, Schlitt M, Knecht H, Herrmann D, Reigl T, Krejci A, Bystry V, Darzentas N, Rieger M, Dietrich S, Luft T, Ho AD, Kneba M, Dreger P.

Bone Marrow Transplant. 2017 Apr;52(4):544-551. doi: 10.1038/bmt.2016.305. Epub 2016 Dec 12. Erratum in: Bone Marrow Transplant. 2017 Apr;52(4):656.

PMID:
27941777
13.

Serum Cotinine Does Not Predict Neutralizing Antibodies Against Interferon Beta in an Austrian MS Cohort.

Auer M, Hegen H, Luft T, Bsteh G, Fogdell-Hahn A, Loercher A, Deisenhammer F.

J Interferon Cytokine Res. 2016 Dec;36(12):667-670. Epub 2016 Oct 19.

PMID:
27918711
14.

Expression of CDKN1C in the bone marrow of patients with myelodysplastic syndrome and secondary acute myeloid leukemia is associated with poor survival after conventional chemotherapy.

Radujkovic A, Dietrich S, Andrulis M, Benner A, Longerich T, Pellagatti A, Nanda K, Giese T, Germing U, Baldus S, Boultwood J, Ho AD, Dreger P, Luft T.

Int J Cancer. 2016 Sep 15;139(6):1402-13. doi: 10.1002/ijc.30181. Epub 2016 Jun 3.

15.

Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia.

Craddock C, Labopin M, Robin M, Finke J, Chevallier P, Yakoub-Agha I, Bourhis JH, Sengelov H, Blaise D, Luft T, Hallek M, Kröger N, Nagler A, Mohty M.

Haematologica. 2016 Jul;101(7):879-83. doi: 10.3324/haematol.2015.140996. Epub 2016 Apr 14.

16.

Low serum vitamin D levels are associated with shorter survival after first-line azacitidine treatment in patients with myelodysplastic syndrome and secondary oligoblastic acute myeloid leukemia.

Radujkovic A, Schnitzler P, Ho AD, Dreger P, Luft T.

Clin Nutr. 2017 Apr;36(2):542-551. doi: 10.1016/j.clnu.2016.01.021. Epub 2016 Feb 10.

PMID:
26899917
17.

Development and validation of cell-based luciferase reporter gene assays for measuring neutralizing anti-drug antibodies against interferon beta.

Hermanrud C, Ryner M, Luft T, Jensen PE, Ingenhoven K, Rat D, Deisenhammer F, Sørensen PS, Pallardy M, Sikkema D, Bertotti E, Kramer D, Creeke P, Fogdell-Hahn A; ABIRISK Consortium.

J Immunol Methods. 2016 Mar;430:1-9. doi: 10.1016/j.jim.2016.01.004. Epub 2016 Jan 11.

PMID:
26779831
18.

Pre-transplant weight loss predicts inferior outcome after allogeneic stem cell transplantation in patients with myelodysplastic syndrome.

Radujkovic A, Becker N, Benner A, Penack O, Platzbecker U, Stölzel F, Bornhäuser M, Hegenbart U, Ho AD, Dreger P, Luft T.

Oncotarget. 2015 Oct 27;6(33):35095-106. doi: 10.18632/oncotarget.4805.

19.

Allogeneic hematopoietic stem cell transplantation for poor-risk CLL: dissecting immune-modulating strategies for disease eradication and treatment of relapse.

Hahn M, Böttcher S, Dietrich S, Hegenbart U, Rieger M, Stadtherr P, Bondong A, Schulz R, Ritgen M, Schmitt T, Tran TH, Görner M, Herth I, Luft T, Schönland S, Witzens-Harig M, Zenz T, Kneba M, Ho AD, Dreger P.

Bone Marrow Transplant. 2015 Oct;50(10):1279-85. doi: 10.1038/bmt.2015.150. Epub 2015 Jul 6.

PMID:
26146810
20.

JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter.

Wagner AH, Conzelmann M, Fitzer F, Giese T, Gülow K, Falk CS, Krämer OH, Dietrich S, Hecker M, Luft T.

Biochem Pharmacol. 2015 Jul 1;96(1):52-64. doi: 10.1016/j.bcp.2015.04.019. Epub 2015 Apr 28.

PMID:
25931145
21.

Treatment of acute myeloid leukemia or myelodysplastic syndrome relapse after allogeneic stem cell transplantation with azacitidine and donor lymphocyte infusions--a retrospective multicenter analysis from the German Cooperative Transplant Study Group.

Schroeder T, Rachlis E, Bug G, Stelljes M, Klein S, Steckel NK, Wolf D, Ringhoffer M, Czibere A, Nachtkamp K, Dienst A, Kondakci M, Stadler M, Platzbecker U, Uharek L, Luft T, Fenk R, Germing U, Bornhäuser M, Kröger N, Beelen DW, Haas R, Kobbe G.

Biol Blood Marrow Transplant. 2015 Apr;21(4):653-60. doi: 10.1016/j.bbmt.2014.12.016. Epub 2014 Dec 23.

22.

Pretransplant metabolic distress predicts relapse of acute myeloid leukemia after allogeneic stem cell transplantation.

Dietrich S, Radujkovic A, Stölzel F, Falk CS, Benner A, Schaich M, Bornhäuser M, Ehninger G, Krämer A, Hegenbart U, Ho AD, Dreger P, Luft T.

Transplantation. 2015 May;99(5):1065-71. doi: 10.1097/TP.0000000000000471.

PMID:
25340610
23.

Single-Nucleotide Polymorphisms Within the Thrombomodulin Gene (THBD) Predict Mortality in Patients With Graft-Versus-Host Disease.

Rachakonda SP, Penack O, Dietrich S, Blau O, Blau IW, Radujkovic A, Isermann B, Ho AD, Uharek L, Dreger P, Kumar R, Luft T.

J Clin Oncol. 2014 Oct 20;32(30):3421-7. doi: 10.1200/JCO.2013.54.4056. Epub 2014 Sep 15.

PMID:
25225421
24.

In vitro testing of drug combinations employing nilotinib and alkylating agents with regard to pretransplant conditioning treatment of advanced-phase chronic myeloid leukemia.

Radujkovic A, Luft T, Dreger P, Ho AD, Jens Zeller W, Fruehauf S, Topaly J.

Cancer Chemother Pharmacol. 2014 Aug;74(2):427-32. doi: 10.1007/s00280-014-2533-6. Epub 2014 Jul 20.

PMID:
25038611
25.

Visceral leishmaniasis in a patient with relapsed multiple myeloma receiving high-dose melphalan and autologous stem cell transplant.

Radujkovic A, Hundemer M, Eisenbach C, Luft T, Penzel R, Goldschmidt H, Ho AD, Bellos F.

Leuk Lymphoma. 2014 Dec;55(12):2967-9. doi: 10.3109/10428194.2014.911862. Epub 2014 Jun 16. No abstract available.

PMID:
24707945
26.

Azacitidine and low-dose cytarabine in palliative patients with acute myeloid leukemia and high bone marrow blast counts--a retrospective single-center experience.

Radujkovic A, Dietrich S, Bochtler T, Krämer A, Schöning T, Ho AD, Dreger P, Luft T.

Eur J Haematol. 2014 Aug;93(2):112-7. doi: 10.1111/ejh.12308. Epub 2014 Apr 3.

PMID:
24628527
27.

Imatinib-supplemented myeloablative total-body irradiation/cyclophosphamide conditioning prior to allogeneic stem cell transplantation as consolidation treatment in patients with blast crisis of chronic myeloid leukemia.

Radujkovic A, Dreger P, Hegenbart U, Buss EC, Luft T, Ho AD, Fruehauf S, Topaly J.

Eur J Haematol. 2014 Jun;92(6):546-9. doi: 10.1111/ejh.12289. Epub 2014 Mar 15. No abstract available.

PMID:
24527710
28.

The impact of allogeneic stem cell transplantation on the natural course of poor-risk chronic lymphocytic leukemia as defined by the EBMT consensus criteria: a retrospective donor versus no donor comparison.

Herth I, Dietrich S, Benner A, Hegenbart U, Rieger M, Stadtherr P, Bondong A, Tran TH, Weide R, Hensel M, Knauf W, Franz-Werner J, Welslau M, Procaccianti M, Görner M, Meissner J, Luft T, Schönland S, Witzens-Harig M, Zenz T, Ho AD, Dreger P.

Ann Oncol. 2014 Jan;25(1):200-6. doi: 10.1093/annonc/mdt511.

PMID:
24356631
29.

High pre-transplant serum nitrate levels predict risk of acute steroid-refractory graft-versus-host disease in the absence of statin therapy.

Dietrich S, Okun JG, Schmidt K, Falk CS, Wagner AH, Karamustafa S, Radujkovic A, Hegenbart U, Ho AD, Dreger P, Luft T.

Haematologica. 2014 Mar;99(3):541-7. doi: 10.3324/haematol.2013.090209. Epub 2013 Oct 18.

30.

Gastrin-releasing peptide receptor signaling in the integration of stress and memory.

Roesler R, Kent P, Luft T, Schwartsmann G, Merali Z.

Neurobiol Learn Mem. 2014 Jul;112:44-52. doi: 10.1016/j.nlm.2013.08.013. Epub 2013 Aug 31. Review.

PMID:
24001571
31.

Risk factors and containment of respiratory syncytial virus outbreak in a hematology and transplant unit.

Lehners N, Schnitzler P, Geis S, Puthenparambil J, Benz MA, Alber B, Luft T, Dreger P, Eisenbach C, Kunz C, Benner A, Buchholz U, Aichinger E, Frank U, Heeg K, Ho AD, Egerer G.

Bone Marrow Transplant. 2013 Nov;48(12):1548-53. doi: 10.1038/bmt.2013.94. Epub 2013 Jul 1.

PMID:
23811816
32.

Azacitidine and donor lymphocyte infusions as first salvage therapy for relapse of AML or MDS after allogeneic stem cell transplantation.

Schroeder T, Czibere A, Platzbecker U, Bug G, Uharek L, Luft T, Giagounidis A, Zohren F, Bruns I, Wolschke C, Rieger K, Fenk R, Germing U, Haas R, Kröger N, Kobbe G.

Leukemia. 2013 Jun;27(6):1229-35. doi: 10.1038/leu.2013.7. Epub 2013 Jan 14.

PMID:
23314834
33.

Endothelial vulnerability and endothelial damage are associated with risk of graft-versus-host disease and response to steroid treatment.

Dietrich S, Falk CS, Benner A, Karamustafa S, Hahn E, Andrulis M, Hegenbart U, Ho AD, Dreger P, Luft T.

Biol Blood Marrow Transplant. 2013 Jan;19(1):22-7. doi: 10.1016/j.bbmt.2012.09.018. Epub 2012 Oct 3.

34.

Loss of endothelial thrombomodulin predicts response to steroid therapy and survival in acute intestinal graft-versus-host disease.

Andrulis M, Dietrich S, Longerich T, Koschny R, Burian M, Schmitt-Gräf A, Schirmacher P, Ho AD, Dreger P, Luft T.

Haematologica. 2012 Nov;97(11):1674-7. doi: 10.3324/haematol.2011.061051. Epub 2012 Jun 11.

35.

Leflunomide induces apoptosis in fludarabine-resistant and clinically refractory CLL cells.

Dietrich S, Krämer OH, Hahn E, Schäfer C, Giese T, Hess M, Tretter T, Rieger M, Hüllein J, Zenz T, Ho AD, Dreger P, Luft T.

Clin Cancer Res. 2012 Jan 15;18(2):417-31. doi: 10.1158/1078-0432.CCR-11-1049. Epub 2011 Nov 9.

36.

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala.

Réus GZ, Stringari RB, Ribeiro KF, Luft T, Abelaira HM, Fries GR, Aguiar BW, Kapczinski F, Hallak JE, Zuardi AW, Crippa JA, Quevedo J.

Acta Neuropsychiatr. 2011 Oct;23(5):241-8. doi: 10.1111/j.1601-5215.2011.00579.x. No abstract available.

PMID:
25379896
37.

Steroid-refractory GVHD: T-cell attack within a vulnerable endothelial system.

Luft T, Dietrich S, Falk C, Conzelmann M, Hess M, Benner A, Neumann F, Isermann B, Hegenbart U, Ho AD, Dreger P.

Blood. 2011 Aug 11;118(6):1685-92. doi: 10.1182/blood-2011-02-334821. Epub 2011 Jun 2.

38.

IFN-γ activated JAK1 shifts CD40-induced cytokine profiles in human antigen-presenting cells toward high IL-12p70 and low IL-10 production.

Conzelmann M, Wagner AH, Hildebrandt A, Rodionova E, Hess M, Zota A, Giese T, Falk CS, Ho AD, Dreger P, Hecker M, Luft T.

Biochem Pharmacol. 2010 Dec 15;80(12):2074-86. doi: 10.1016/j.bcp.2010.07.040. Epub 2010 Aug 13.

PMID:
20709027
39.

Pentostatin for treatment of steroid-refractory acute GVHD: a retrospective single-center analysis.

Schmitt T, Luft T, Hegenbart U, Tran TH, Ho AD, Dreger P.

Bone Marrow Transplant. 2011 Apr;46(4):580-5. doi: 10.1038/bmt.2010.146. Epub 2010 Jun 21.

PMID:
20562925
40.

Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing.

Andrulis M, Capper D, Luft T, Hartmann C, Zentgraf H, von Deimling A.

Leuk Res. 2010 Aug;34(8):1091-3. doi: 10.1016/j.leukres.2010.02.014. Epub 2010 Mar 12.

PMID:
20227112
41.

Phosphoinositide 3-kinase is required for bombesin-induced enhancement of fear memory consolidation in the hippocampus.

Roesler R, Valvassori SS, Castro AA, Luft T, Schwartsmann G, Quevedo J.

Peptides. 2009 Jun;30(6):1192-6. doi: 10.1016/j.peptides.2009.02.007. Epub 2009 Feb 21.

PMID:
19463755
42.
43.

Thymus repopulation after allogeneic reconstitution in hematological malignancies.

Zöller M, Rajasagi M, Vitacolonna M, Luft T.

Exp Hematol. 2007 Dec;35(12):1891-905. Epub 2007 Oct 17.

PMID:
17920753
44.

Serum cytokeratin-18 fragments as quantitative markers of epithelial apoptosis in liver and intestinal graft-versus-host disease.

Luft T, Conzelmann M, Benner A, Rieger M, Hess M, Strohhaecker U, Görner M, Hegenbart U, Ho AD, Dreger P.

Blood. 2007 Dec 15;110(13):4535-42. Epub 2007 Aug 16.

45.

Basic fibroblast growth factor prevents the memory impairment induced by gastrin-releasing peptide receptor antagonism in area CA1 of the rat hippocampus.

Preissler T, Luft T, Kapczinski F, Quevedo J, Schwartsmann G, Roesler R.

Neurochem Res. 2007 Aug;32(8):1381-6. Epub 2007 Apr 4.

PMID:
17406984
46.

Temporary inactivation of the dorsal hippocampus induces a transient impairment in retrieval of aversive memory.

Amaral OB, Luft T, Cammarota M, Izquierdo I, Roesler R.

Behav Brain Res. 2007 Jun 18;180(2):113-8. Epub 2007 Feb 25.

PMID:
17403545
47.

Targeting the gastrin-releasing peptide receptor pathway to treat cognitive dysfunctionassociated with Alzheimer's Disease.

Roesler R, Luft T, Schwartsmann G.

Dement Neuropsychol. 2007 Apr-Jun;1(2):118-123. doi: 10.1590/s1980-57642008dn10200002. Review.

48.

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells.

Rodionova E, Conzelmann M, Maraskovsky E, Hess M, Kirsch M, Giese T, Ho AD, Zöller M, Dreger P, Luft T.

Blood. 2007 Feb 15;109(4):1584-92. Epub 2006 Oct 10.

49.

Booster vaccination in the elderly: their success depends on the vaccine type applied earlier in life as well as on pre-vaccination antibody titers.

Kaml M, Weiskirchner I, Keller M, Luft T, Hoster E, Hasford J, Young L, Bartlett B, Neuner C, Fischer KH, Neuman B, Würzner R, Grubeck-Loebenstein B.

Vaccine. 2006 Nov 17;24(47-48):6808-11. Epub 2006 Jul 10.

PMID:
16872725
50.

Temporary inactivation reveals an essential role of the dorsal hippocampus in consolidation of object recognition memory.

de Lima MN, Luft T, Roesler R, Schröder N.

Neurosci Lett. 2006 Sep 11;405(1-2):142-6. Epub 2006 Jul 18.

PMID:
16854527

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