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Items: 1 to 50 of 60

1.

Three-Component Bioorthogonal Reactions on Cellular DNA and RNA.

Tera M, Luedtke NW.

Bioconjug Chem. 2019 Nov 13. doi: 10.1021/acs.bioconjchem.9b00630. [Epub ahead of print]

PMID:
31697067
2.

Concerted dynamics of metallo-base pairs in an A/B-form helical transition.

Schmidt OP, Jurt S, Johannsen S, Karimi A, Sigel RKO, Luedtke NW.

Nat Commun. 2019 Oct 23;10(1):4818. doi: 10.1038/s41467-019-12440-x.

3.

Enzymatic Incorporation of a Coumarin-Guanine Base Pair.

Johnson A, Karimi A, Luedtke NW.

Angew Chem Int Ed Engl. 2019 Nov 18;58(47):16839-16843. doi: 10.1002/anie.201910059. Epub 2019 Oct 14.

PMID:
31486266
4.

Intercalation-enhanced "Click" Crosslinking of DNA.

Tera M, Harati Taji Z, Luedtke NW.

Angew Chem Int Ed Engl. 2018 Nov 19;57(47):15405-15409. doi: 10.1002/anie.201808054. Epub 2018 Oct 25.

PMID:
30240107
5.

In Vivo Incorporation of Azide Groups into DNA by Using Membrane-Permeable Nucleotide Triesters.

Tera M, Glasauer SMK, Luedtke NW.

Chembiochem. 2018 Sep 17;19(18):1939-1943. doi: 10.1002/cbic.201800351. Epub 2018 Aug 8.

PMID:
29953711
6.

HgII binds to C-T mismatches with high affinity.

Schmidt OP, Benz AS, Mata G, Luedtke NW.

Nucleic Acids Res. 2018 Jul 27;46(13):6470-6479. doi: 10.1093/nar/gky499.

7.

Superresolution imaging of individual replication forks reveals unexpected prodrug resistance mechanism.

Triemer T, Messikommer A, Glasauer SMK, Alzeer J, Paulisch MH, Luedtke NW.

Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):E1366-E1373. doi: 10.1073/pnas.1714790115. Epub 2018 Jan 29.

8.

Chemoselective Modification of Vinyl DNA by Triazolinediones.

Naik A, Alzeer J, Triemer T, Bujalska A, Luedtke NW.

Angew Chem Int Ed Engl. 2017 Aug 28;56(36):10850-10853. doi: 10.1002/anie.201702554. Epub 2017 Aug 4.

PMID:
28561928
9.

DNA-Targeted Inhibition of MGMT.

Marsoner T, Schmidt OP, Triemer T, Luedtke NW.

Chembiochem. 2017 May 18;18(10):894-898. doi: 10.1002/cbic.201600652. Epub 2017 Apr 7.

PMID:
28177192
10.

Fluorescent Base Analogue Reveals T-HgII-T Base Pairs Have High Kinetic Stabilities That Perturb DNA Metabolism.

Schmidt OP, Mata G, Luedtke NW.

J Am Chem Soc. 2016 Nov 9;138(44):14733-14739. Epub 2016 Oct 25.

PMID:
27709934
11.

A fluorescent surrogate of thymidine in duplex DNA.

Mata G, Schmidt OP, Luedtke NW.

Chem Commun (Camb). 2016 Mar 28;52(25):4718-21. doi: 10.1039/c5cc09552b.

PMID:
26954231
12.

Fluorescent chemosensors of carbohydrate triols exhibiting TICT emissions.

Oesch D, Luedtke NW.

Chem Commun (Camb). 2015 Aug 14;51(63):12641-4. doi: 10.1039/c5cc03857j.

PMID:
26160311
13.

A Bioorthogonal Chemical Reporter of Viral Infection.

Neef AB, Pernot L, Schreier VN, Scapozza L, Luedtke NW.

Angew Chem Int Ed Engl. 2015 Jun 26;54(27):7911-4. doi: 10.1002/anie.201500250. Epub 2015 May 14.

PMID:
25974835
14.

Synthesis of 2-Oxazolines by in Situ Desilylation and Cyclodehydration of β-Hydroxyamides.

Brandstätter M, Roth F, Luedtke NW.

J Org Chem. 2015 Jan 2;80(1):40-51. doi: 10.1021/jo5016695. Epub 2014 Dec 18.

PMID:
25457734
15.

Fluorescent probe for proton-coupled DNA folding revealing slow exchange of i-motif and duplex structures.

Mata G, Luedtke NW.

J Am Chem Soc. 2015 Jan 21;137(2):699-707. doi: 10.1021/ja508741u. Epub 2015 Jan 13.

PMID:
25423623
16.

Alkene-tetrazine ligation for imaging cellular DNA.

Rieder U, Luedtke NW.

Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9168-72. doi: 10.1002/anie.201403580. Epub 2014 Jun 30.

PMID:
24981416
17.

An azide-modified nucleoside for metabolic labeling of DNA.

Neef AB, Luedtke NW.

Chembiochem. 2014 Apr 14;15(6):789-93. doi: 10.1002/cbic.201400037. Epub 2014 Mar 18.

PMID:
24644275
18.

Characterization of chromosomal architecture in Arabidopsis by chromosome conformation capture.

Grob S, Schmid MW, Luedtke NW, Wicker T, Grossniklaus U.

Genome Biol. 2013 Nov 24;14(11):R129. doi: 10.1186/gb-2013-14-11-r129.

19.

Tracking viral genomes in host cells at single-molecule resolution.

Wang IH, Suomalainen M, Andriasyan V, Kilcher S, Mercer J, Neef A, Luedtke NW, Greber UF.

Cell Host Microbe. 2013 Oct 16;14(4):468-80. doi: 10.1016/j.chom.2013.09.004.

20.

Photodynamic agents with anti-metastatic activities.

Vummidi BR, Noreen F, Alzeer J, Moelling K, Luedtke NW.

ACS Chem Biol. 2013 Aug 16;8(8):1737-46. doi: 10.1021/cb400008t. Epub 2013 May 28.

PMID:
23672401
21.

Synthesis and solvatochromic fluorescence of biaryl pyrimidine nucleosides.

Mata G, Luedtke NW.

Org Lett. 2013 May 17;15(10):2462-5. doi: 10.1021/ol400930s. Epub 2013 May 8.

PMID:
23656574
22.

Fluorescent probes for G-quadruplex structures.

Vummidi BR, Alzeer J, Luedtke NW.

Chembiochem. 2013 Mar 18;14(5):540-58. doi: 10.1002/cbic.201200612. Epub 2013 Feb 25. Review.

PMID:
23440895
23.

Synthesis and structure of a hydrogenated zinc hemiporphyrazine.

Huber SM, Mata G, Linden A, Luedtke NW.

Chem Commun (Camb). 2013 May 14;49(39):4280-2. doi: 10.1039/c2cc37151k. Epub 2012 Nov 13.

PMID:
23149500
24.

Stereoselective N-glycosylation of 2-deoxythioribosides for fluorescent nucleoside synthesis.

Mata G, Luedtke NW.

J Org Chem. 2012 Oct 19;77(20):9006-17. doi: 10.1021/jo3014929. Epub 2012 Oct 5.

PMID:
22974063
25.

Metabolic labeling of DNA by purine analogues in vivo.

Neef AB, Samain F, Luedtke NW.

Chembiochem. 2012 Aug 13;13(12):1750-3. doi: 10.1002/cbic.201200253. Epub 2012 Jul 20. No abstract available.

PMID:
22815258
26.

Excitonic luminescence of hemiporphyrazines.

Huber SM, Seyfried MS, Linden A, Luedtke NW.

Inorg Chem. 2012 Jul 2;51(13):7032-8. doi: 10.1021/ic2017566. Epub 2012 Jun 15.

27.

Enantioselective and label-free detection of oligopeptide via fluorescent indicator displacement.

Ren J, Wang J, Wang J, Luedtke NW, Wang E.

Biosens Bioelectron. 2012 May 15;35(1):401-406. doi: 10.1016/j.bios.2012.03.028. Epub 2012 Mar 23.

PMID:
22483357
28.

Synthesis of DNA interstrand cross-links using a photocaged nucleobase.

Hentschel S, Alzeer J, Angelov T, Schärer OD, Luedtke NW.

Angew Chem Int Ed Engl. 2012 Apr 2;51(14):3466-9. doi: 10.1002/anie.201108018. Epub 2012 Feb 17.

PMID:
22344895
29.

Site-specific control of N7-metal coordination in DNA by a fluorescent purine derivative.

Dumas A, Luedtke NW.

Chemistry. 2012 Jan 2;18(1):245-54. doi: 10.1002/chem.201102349. Epub 2011 Dec 5.

PMID:
22143992
30.

Dynamic metabolic labeling of DNA in vivo with arabinosyl nucleosides.

Neef AB, Luedtke NW.

Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20404-9. doi: 10.1073/pnas.1101126108. Epub 2011 Dec 5.

31.

Contribution of potassium ion and split modes of G-quadruplex to the sensitivity and selectivity of label-free sensor toward DNA detection using fluorescence.

Ren J, Wang J, Wang J, Luedtke NW, Wang E.

Biosens Bioelectron. 2012 Jan 15;31(1):316-22. doi: 10.1016/j.bios.2011.10.038. Epub 2011 Oct 25.

PMID:
22104647
32.

Fluorescence properties of 8-(2-pyridyl)guanine "2PyG" as compared to 2-aminopurine in DNA.

Dumas A, Luedtke NW.

Chembiochem. 2011 Sep 5;12(13):2044-51. doi: 10.1002/cbic.201100214. Epub 2011 Jul 22.

PMID:
21786378
33.

Highly fluorescent guanosine mimics for folding and energy transfer studies.

Dumas A, Luedtke NW.

Nucleic Acids Res. 2011 Aug;39(15):6825-34. doi: 10.1093/nar/gkr281. Epub 2011 May 6.

34.

Label-free detection of nucleic acids by turn-on and turn-off G-quadruplex-mediated fluorescence.

Ren J, Qin H, Wang J, Luedtke NW, Wang E, Wang J.

Anal Bioanal Chem. 2011 Mar;399(8):2763-70. doi: 10.1007/s00216-011-4669-0. Epub 2011 Jan 26.

PMID:
21267713
35.

Cation-mediated energy transfer in G-quadruplexes revealed by an internal fluorescent probe.

Dumas A, Luedtke NW.

J Am Chem Soc. 2010 Dec 29;132(51):18004-7. doi: 10.1021/ja1079578. Epub 2010 Dec 2.

PMID:
21125997
36.

G-quadruplex-modulated fluorescence detection of potassium in the presence of a 3500-fold excess of sodium ions.

Qin H, Ren J, Wang J, Luedtke NW, Wang E.

Anal Chem. 2010 Oct 1;82(19):8356-60. doi: 10.1021/ac101894b.

PMID:
20804164
37.

pH-mediated fluorescence and G-quadruplex binding of amido phthalocyanines.

Alzeer J, Luedtke NW.

Biochemistry. 2010 May 25;49(20):4339-48. doi: 10.1021/bi9020583.

PMID:
20380429
38.

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes.

Membrino A, Paramasivam M, Cogoi S, Alzeer J, Luedtke NW, Xodo LE.

Chem Commun (Camb). 2010 Jan 28;46(4):625-7. doi: 10.1039/b918964e. Epub 2009 Nov 20.

39.

Multiple-turnover isotopic labeling of Fmoc- and Boc-protected amino acids with oxygen isotopes.

Seyfried MS, Lauber BS, Luedtke NW.

Org Lett. 2010 Jan 1;12(1):104-6. doi: 10.1021/ol902519g.

PMID:
20035564
40.

Guanidinium-modified phthalocyanines as high-affinity G-quadruplex fluorescent probes and transcriptional regulators.

Alzeer J, Vummidi BR, Roth PJ, Luedtke NW.

Angew Chem Int Ed Engl. 2009;48(49):9362-5. doi: 10.1002/anie.200903685. No abstract available.

PMID:
19882707
41.

An efficient two-step synthesis of metal-free phthalocyanines using a Zn(ii) template.

Alzeer J, Roth PJ, Luedtke NW.

Chem Commun (Camb). 2009 Apr 21;(15):1970-1. doi: 10.1039/b822985f. Epub 2009 Mar 11.

42.

Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH.

Luedtke NW, Dexter RJ, Fried DB, Schepartz A.

Nat Chem Biol. 2007 Dec;3(12):779-84. Epub 2007 Nov 4.

43.

Lanthanide-mediated phosphoester hydrolysis and phosphate elimination from phosphopeptides.

Luedtke NW, Schepartz A.

Chem Commun (Camb). 2005 Nov 21;(43):5426-8. Epub 2005 Sep 30.

PMID:
16261235
44.

A rapid library screen for tailoring beta-peptide structure and function.

Kritzer JA, Luedtke NW, Harker EA, Schepartz A.

J Am Chem Soc. 2005 Oct 26;127(42):14584-5.

45.

Chemical biology: innovative solutions for diverse challenges.

Kritzer JA, Luedtke NW.

Chem Biol. 2005 Jun;12(6):617-20. No abstract available.

46.

RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides.

Boer J, Blount KF, Luedtke NW, Elson-Schwab L, Tor Y.

Angew Chem Int Ed Engl. 2005 Jan 28;44(6):927-32. No abstract available.

PMID:
15630712
47.

On the electronic structure of ethidium.

Luedtke NW, Liu Q, Tor Y.

Chemistry. 2005 Jan 7;11(2):495-508.

PMID:
15549769
48.

Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+.

Aldrich-Wright J, Brodie C, Glazer EC, Luedtke NW, Elson-Schwab L, Tor Y.

Chem Commun (Camb). 2004 Apr 21;(8):1018-9. Epub 2004 Mar 23.

PMID:
15069523
49.
50.

Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine.

Luedtke NW, Carmichael P, Tor Y.

J Am Chem Soc. 2003 Oct 15;125(41):12374-5.

PMID:
14531657

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