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Improving the Quality of Dietary Research.

Ludwig DS, Ebbeling CB, Heymsfield SB.

JAMA. 2019 Aug 12. doi: 10.1001/jama.2019.11169. [Epub ahead of print] No abstract available.


Ultra-Processed Food and Obesity: The Pitfalls of Extrapolation from Short Studies.

Ludwig DS, Astrup A, Bazzano LA, Ebbeling CB, Heymsfield SB, King JC, Willett WC.

Cell Metab. 2019 Jul 2;30(1):3-4. doi: 10.1016/j.cmet.2019.06.004. Epub 2019 Jun 20. No abstract available.


Dietary fat: From foe to friend?

Ludwig DS, Willett WC, Volek JS, Neuhouser ML.

Science. 2018 Nov 16;362(6416):764-770. doi: 10.1126/science.aau2096. Review.


Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial.

Ebbeling CB, Feldman HA, Klein GL, Wong JMW, Bielak L, Steltz SK, Luoto PK, Wolfe RR, Wong WW, Ludwig DS.

BMJ. 2018 Nov 14;363:k4583. doi: 10.1136/bmj.k4583.


An Academia-Industry Partnership for Planning and Executing a Community-Based Feeding Study.

Wong JM, Bielak L, Eddy RG, Stone L, Lakin PR, Sandman M, Devlin C, Seger-Shippee L, Wiroll D, Luoto PK, Klein GL, Ludwig DS, Ebbeling CB.

Curr Dev Nutr. 2018 Jul 5;2(9):nzy060. doi: 10.1093/cdn/nzy060. eCollection 2018 Sep.


90th Anniversary Commentary: Obesity among Offspring of US Immigrants: After 20 Years, a Need to Safeguard Children from the Obesogenic Environment.

Ludwig DS, Ebbeling CB.

J Nutr. 2018 Oct 1;148(10):1674-1677. doi: 10.1093/jn/nxy152. No abstract available.


Authors' Response.

Ludwig DS, Lennerz BS.

Pediatrics. 2018 Aug;142(2). pii: e20181536C. doi: 10.1542/peds.2018-1536C. No abstract available.


The Carbohydrate-Insulin Model of Obesity: Beyond "Calories In, Calories Out".

Ludwig DS, Ebbeling CB.

JAMA Intern Med. 2018 Aug 1;178(8):1098-1103. doi: 10.1001/jamainternmed.2018.2933. Review.


Conflicts of Interest in Nutrition Research.

Ludwig DS, Kushi LH, Heymsfield SB.

JAMA. 2018 Jul 3;320(1):93. doi: 10.1001/jama.2018.5658. No abstract available.


Incorrect analyses were used in "Different enteral nutrition formulas have no effect on glucose homeostasis but on diet-induced thermogenesis in critically ill medical patients: a randomized controlled trial" and corrected analyses are requested.

Dickinson SL, Brown AW, Mehta T, Heymsfield SB, Ebbeling CB, Ludwig DS, Allison DB.

Eur J Clin Nutr. 2019 Jan;73(1):152-153. doi: 10.1038/s41430-018-0197-8. Epub 2018 Jun 27. No abstract available.


Dietary carbohydrates: role of quality and quantity in chronic disease.

Ludwig DS, Hu FB, Tappy L, Brand-Miller J.

BMJ. 2018 Jun 13;361:k2340. doi: 10.1136/bmj.k2340. Review. No abstract available.


Management of Type 1 Diabetes With a Very Low-Carbohydrate Diet.

Lennerz BS, Barton A, Bernstein RK, Dikeman RD, Diulus C, Hallberg S, Rhodes ET, Ebbeling CB, Westman EC, Yancy WS Jr, Ludwig DS.

Pediatrics. 2018 Jun;141(6). pii: e20173349. doi: 10.1542/peds.2017-3349. Epub 2018 May 7.


Source of bias in sugar-sweetened beverage research: a systematic review.

Litman EA, Gortmaker SL, Ebbeling CB, Ludwig DS.

Public Health Nutr. 2018 Aug;21(12):2345-2350. doi: 10.1017/S1368980018000575. Epub 2018 Mar 26.


Epidemic Childhood Obesity: Not Yet the End of the Beginning.

Ludwig DS.

Pediatrics. 2018 Mar;141(3). pii: e20174078. doi: 10.1542/peds.2017-4078. No abstract available.


Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity.

Astley CM, Todd JN, Salem RM, Vedantam S, Ebbeling CB, Huang PL, Ludwig DS, Hirschhorn JN, Florez JC.

Clin Chem. 2018 Jan;64(1):192-200. doi: 10.1373/clinchem.2017.280727.


A randomized study of dietary composition during weight-loss maintenance: Rationale, study design, intervention, and assessment.

Ebbeling CB, Klein GL, Luoto PK, Wong JMW, Bielak L, Eddy RG, Steltz SK, Devlin C, Sandman M, Hron B, Shimy K, Heymsfield SB, Wolfe RR, Wong WW, Feldman HA, Ludwig DS.

Contemp Clin Trials. 2018 Feb;65:76-86. doi: 10.1016/j.cct.2017.12.004. Epub 2017 Dec 9.


Dietary Fat: Friend or Foe?

Ebbeling CB, Young IS, Lichtenstein AH, Ludwig DS, McKinley M, Perez-Escamilla R, Rimm E.

Clin Chem. 2018 Jan;64(1):34-41. doi: 10.1373/clinchem.2017.274084. Epub 2017 Nov 8. No abstract available.


Carbohydrate-last meal pattern lowers postprandial glucose and insulin excursions in type 2 diabetes.

Shukla AP, Andono J, Touhamy SH, Casper A, Iliescu RG, Mauer E, Shan Zhu Y, Ludwig DS, Aronne LJ.

BMJ Open Diabetes Res Care. 2017 Sep 14;5(1):e000440. doi: 10.1136/bmjdrc-2017-000440. eCollection 2017.


Hepatic, adipocyte, enteric and pancreatic hormones: response to dietary macronutrient composition and relationship with metabolism.

Hron BM, Ebbeling CB, Feldman HA, Ludwig DS.

Nutr Metab (Lond). 2017 Jul 5;14:44. doi: 10.1186/s12986-017-0198-y. eCollection 2017.


Effects of Advice to Drink 8 Cups of Water per Day in Adolescents With Overweight or Obesity: A Randomized Clinical Trial.

Wong JMW, Ebbeling CB, Robinson L, Feldman HA, Ludwig DS.

JAMA Pediatr. 2017 May 1;171(5):e170012. doi: 10.1001/jamapediatrics.2017.0012. Epub 2017 May 1.


Glycemic index is as reliable as macronutrients on food labels.

Wolever TM, Augustin LS, Brand-Miller JC, Delport E, Livesey G, Ludwig DS, Sievenpiper JL.

Am J Clin Nutr. 2017 Mar;105(3):768-769. doi: 10.3945/ajcn.116.146092. No abstract available.


Calorically restricted diets decrease PCSK9 in overweight adolescents.

Levenson AE, Milliren CE, Biddinger SB, Ebbeling CB, Feldman HA, Ludwig DS, de Ferranti SD.

Nutr Metab Cardiovasc Dis. 2017 Apr;27(4):342-349. doi: 10.1016/j.numecd.2016.12.010. Epub 2017 Jan 3.


Metabolomic profiles as reliable biomarkers of dietary composition.

Esko T, Hirschhorn JN, Feldman HA, Hsu YH, Deik AA, Clish CB, Ebbeling CB, Ludwig DS.

Am J Clin Nutr. 2017 Mar;105(3):547-554. doi: 10.3945/ajcn.116.144428. Epub 2017 Jan 11.


Creating an integrated care model for childhood obesity: a randomized pilot study utilizing telehealth in a community primary care setting.

Fleischman A, Hourigan SE, Lyon HN, Landry MG, Reynolds J, Steltz SK, Robinson L, Keating S, Feldman HA, Antonelli RC, Ludwig DS, Ebbeling CB.

Clin Obes. 2016 Dec;6(6):380-388. doi: 10.1111/cob.12166. Epub 2016 Nov 14.


Raising the bar on the low-carbohydrate diet.

Ludwig DS, Ebbeling CB.

Am J Clin Nutr. 2016 Nov;104(5):1487-1488. No abstract available.


Lowering the Bar on the Low-Fat Diet.

Ludwig DS.

JAMA. 2016 Nov 22;316(20):2087-2088. doi: 10.1001/jama.2016.15473. No abstract available.


A telephone intervention to achieve differentiation in dietary intake: a randomized trial in paediatric primary care.

Rhodes ET, Vernacchio L, Mitchell AA, Fischer C, Giacalone P, Ludwig DS, Ebbeling CB.

Pediatr Obes. 2017 Dec;12(6):494-501. doi: 10.1111/ijpo.12171. Epub 2016 Aug 5.


Outcomes from an orientation model to reduce attrition in paediatric weight management.

Zenlea IS, Milliren C, Herel S, Thomaseo Burton E, Askins N, Ludwig DS, Rhodes ET.

Clin Obes. 2016 Oct;6(5):313-20. doi: 10.1111/cob.12156. Epub 2016 Aug 4.


Lifespan Weighed Down by Diet.

Ludwig DS.

JAMA. 2016 Jun 7;315(21):2269-70. doi: 10.1001/jama.2016.3829. No abstract available.


Correction: Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies.

Bertoia ML, Mukamal KJ, Cahill LE, Hou T, Ludwig DS, Mozaffarian D, Willett WC, Hu FB, Rimm EB.

PLoS Med. 2016 Jan 20;13(1):e1001956. doi: 10.1371/journal.pmed.1001956. eCollection 2016 Jan. No abstract available.


Dietary Cholesterol and Blood Cholesterol Concentrations-Reply.

Mozaffarian D, Ludwig DS.

JAMA. 2015 Nov 17;314(19):2084-5. doi: 10.1001/jama.2015.12604. No abstract available.


Effect of low-fat diet interventions versus other diet interventions on long-term weight change in adults: a systematic review and meta-analysis.

Tobias DK, Chen M, Manson JE, Ludwig DS, Willett W, Hu FB.

Lancet Diabetes Endocrinol. 2015 Dec;3(12):968-79. doi: 10.1016/S2213-8587(15)00367-8. Epub 2015 Oct 30. Review.


Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies.

Bertoia ML, Mukamal KJ, Cahill LE, Hou T, Ludwig DS, Mozaffarian D, Willett WC, Hu FB, Rimm EB.

PLoS Med. 2015 Sep 22;12(9):e1001878. doi: 10.1371/journal.pmed.1001878. eCollection 2015 Sep. Erratum in: PLoS Med. 2016 Jan;13(1):e1001956.


Relationship of insulin dynamics to body composition and resting energy expenditure following weight loss.

Hron BM, Ebbeling CB, Feldman HA, Ludwig DS.

Obesity (Silver Spring). 2015 Nov;23(11):2216-22. doi: 10.1002/oby.21213. Epub 2015 Sep 16.


Providing food to treat adolescents at risk for cardiovascular disease.

de Ferranti SD, Milliren CE, Denhoff ER, Quinn N, Osganian SK, Feldman HA, Ebbeling CB, Ludwig DS.

Obesity (Silver Spring). 2015 Oct;23(10):2109-17. doi: 10.1002/oby.21246. Epub 2015 Sep 4.


Physical changes in the home environment to reduce television viewing and sugar-sweetened beverage consumption among 5- to 12-year-old children: a randomized pilot study.

French SA, Sherwood NE, JaKa MM, Haapala JL, Ebbeling CB, Ludwig DS.

Pediatr Obes. 2016 Oct;11(5):e12-5. doi: 10.1111/ijpo.12067. Epub 2015 Aug 28.


A randomized pilot study of dietary treatments for polycystic ovary syndrome in adolescents.

Wong JM, Gallagher M, Gooding H, Feldman HA, Gordon CM, Ludwig DS, Ebbeling CB.

Pediatr Obes. 2016 Jun;11(3):210-20. doi: 10.1111/ijpo.12047. Epub 2015 Jul 1.


The 2015 US Dietary Guidelines: Lifting the Ban on Total Dietary Fat.

Mozaffarian D, Ludwig DS.

JAMA. 2015 Jun 23-30;313(24):2421-2. doi: 10.1001/jama.2015.5941. No abstract available.


The glycemic index: Reports of its demise have been exaggerated.

Ludwig DS, Astrup A, Willett WC.

Obesity (Silver Spring). 2015 Jul;23(7):1327-8. doi: 10.1002/oby.21125. Epub 2015 May 13. No abstract available.


Changes in intake of protein foods, carbohydrate amount and quality, and long-term weight change: results from 3 prospective cohorts.

Smith JD, Hou T, Ludwig DS, Rimm EB, Willett W, Hu FB, Mozaffarian D.

Am J Clin Nutr. 2015 Jun;101(6):1216-24. doi: 10.3945/ajcn.114.100867. Epub 2015 Apr 8.


Multi-component molecular-level body composition reference methods: evolving concepts and future directions.

Heymsfield SB, Ebbeling CB, Zheng J, Pietrobelli A, Strauss BJ, Silva AM, Ludwig DS.

Obes Rev. 2015 Apr;16(4):282-94. doi: 10.1111/obr.12261. Epub 2015 Feb 3. Review.


Taxes and subsidies to improve diet--reply.

Mozaffarian D, Rogoff KS, Ludwig DS.

JAMA. 2015 Jan 20;313(3):308. doi: 10.1001/jama.2014.15641. No abstract available.


Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans.

Lennerz BS, Vafai SB, Delaney NF, Clish CB, Deik AA, Pierce KA, Ludwig DS, Mootha VK.

Mol Genet Metab. 2015 Jan;114(1):73-9. doi: 10.1016/j.ymgme.2014.11.010. Epub 2014 Nov 15.


The real cost of food: can taxes and subsidies improve public health?

Mozaffarian D, Rogoff KS, Ludwig DS.

JAMA. 2014 Sep 3;312(9):889-90. doi: 10.1001/jama.2014.8232. No abstract available.


Increasing adiposity: consequence or cause of overeating?

Ludwig DS, Friedman MI.

JAMA. 2014 Jun 4;311(21):2167-8. No abstract available. Erratum in: JAMA. 2014 Jun 4;311(21):2168.


How early should obesity prevention start?

Gillman MW, Ludwig DS.

N Engl J Med. 2013 Dec 5;369(23):2173-5. doi: 10.1056/NEJMp1310577. Epub 2013 Nov 13. No abstract available.


Pregnancy weight gain and childhood body weight: a within-family comparison.

Ludwig DS, Rouse HL, Currie J.

PLoS Med. 2013 Oct;10(10):e1001521. doi: 10.1371/journal.pmed.1001521. Epub 2013 Oct 1.


Three daily servings of reduced-fat milk: an evidence-based recommendation?

Ludwig DS, Willett WC.

JAMA Pediatr. 2013 Sep;167(9):788-9. doi: 10.1001/jamapediatrics.2013.2408. No abstract available.


Effects of dietary glycemic index on brain regions related to reward and craving in men.

Lennerz BS, Alsop DC, Holsen LM, Stern E, Rojas R, Ebbeling CB, Goldstein JM, Ludwig DS.

Am J Clin Nutr. 2013 Sep;98(3):641-7. doi: 10.3945/ajcn.113.064113. Epub 2013 Jun 26.


Breakfast frequency and development of metabolic risk.

Odegaard AO, Jacobs DR Jr, Steffen LM, Van Horn L, Ludwig DS, Pereira MA.

Diabetes Care. 2013 Oct;36(10):3100-6. doi: 10.2337/dc13-0316. Epub 2013 Jun 17.

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