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Catalysis-dependent inactivation of human telomerase and its reactivation by intracellular telomerase-activating factors (iTAFs).

Sayed ME, Cheng A, Yadav GP, Ludlow AT, Shay JW, Wright WE, Jiang QX.

J Biol Chem. 2019 Jun 11. pii: jbc.RA118.007234. doi: 10.1074/jbc.RA118.007234. [Epub ahead of print]


Drosophila as a Model for Understanding the Insect Host of Yersinia pestis.

Ludlow AB, Pauling CD, Marketon MM, Anderson DM.

Methods Mol Biol. 2019;2010:167-178. doi: 10.1007/978-1-4939-9541-7_12.


Exploring gender as a potential source of bias in adult judgments of children with specific language impairment and attention-deficit/hyperactivity disorder.

Shimko A, Redmond S, Ludlow A, Ash A.

J Commun Disord. 2019 May 23:105910. doi: 10.1016/j.jcomdis.2019.105910. [Epub ahead of print]


Insights into Telomerase/hTERT Alternative Splicing Regulation Using Bioinformatics and Network Analysis in Cancer.

Ludlow AT, Slusher AL, Sayed ME.

Cancers (Basel). 2019 May 14;11(5). pii: E666. doi: 10.3390/cancers11050666. Review.


An immunotherapy survivor population: health-related quality of life and toxicity in patients with metastatic melanoma treated with immune checkpoint inhibitors.

O'Reilly A, Hughes P, Mann J, Lai Z, Teh JJ, Mclean E, Edmonds K, Lingard K, Chauhan D, Lynch J, Au L, Ludlow A, Pattison N, Wiseman T, Turajlic S, Gore M, Larkin J, Husson O.

Support Care Cancer. 2019 May 14. doi: 10.1007/s00520-019-04818-w. [Epub ahead of print]


The role of sensory sensitivity in predicting food selectivity and food preferences in children with Tourette syndrome.

Smith B, Rogers SL, Blissett J, Ludlow AK.

Appetite. 2019 Apr 1;135:131-136. doi: 10.1016/j.appet.2019.01.003. Epub 2019 Jan 8.


NOVA1 directs PTBP1 to hTERT pre-mRNA and promotes telomerase activity in cancer cells.

Sayed ME, Yuan L, Robin JD, Tedone E, Batten K, Dahlson N, Wright WE, Shay JW, Ludlow AT.

Oncogene. 2019 Apr;38(16):2937-2952. doi: 10.1038/s41388-018-0639-8. Epub 2018 Dec 19.


New bounds on dark matter coupling from a global network of optical atomic clocks.

Wcisło P, Ablewski P, Beloy K, Bilicki S, Bober M, Brown R, Fasano R, Ciuryło R, Hachisu H, Ido T, Lodewyck J, Ludlow A, McGrew W, Morzyński P, Nicolodi D, Schioppo M, Sekido M, Le Targat R, Wolf P, Zhang X, Zjawin B, Zawada M.

Sci Adv. 2018 Dec 7;4(12):eaau4869. doi: 10.1126/sciadv.aau4869. eCollection 2018 Dec.


Telomere length and telomerase activity in T cells are biomarkers of high-performing centenarians.

Tedone E, Huang E, O'Hara R, Batten K, Ludlow AT, Lai TP, Arosio B, Mari D, Wright WE, Shay JW.

Aging Cell. 2019 Feb;18(1):e12859. doi: 10.1111/acel.12859. Epub 2018 Nov 28.


Atomic clock performance enabling geodesy below the centimetre level.

McGrew WF, Zhang X, Fasano RJ, Schäffer SA, Beloy K, Nicolodi D, Brown RC, Hinkley N, Milani G, Schioppo M, Yoon TH, Ludlow AD.

Nature. 2018 Dec;564(7734):87-90. doi: 10.1038/s41586-018-0738-2. Epub 2018 Nov 28.


NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer.

Ludlow AT, Wong MS, Robin JD, Batten K, Yuan L, Lai TP, Dahlson N, Zhang L, Mender I, Tedone E, Sayed ME, Wright WE, Shay JW.

Nat Commun. 2018 Aug 6;9(1):3112. doi: 10.1038/s41467-018-05582-x.


Faraday-Shielded dc Stark-Shift-Free Optical Lattice Clock.

Beloy K, Zhang X, McGrew WF, Hinkley N, Yoon TH, Nicolodi D, Fasano RJ, Schäffer SA, Brown RC, Ludlow AD.

Phys Rev Lett. 2018 May 4;120(18):183201. doi: 10.1103/PhysRevLett.120.183201.


ddTRAP: A Method for Sensitive and Precise Quantification of Telomerase Activity.

Ludlow AT, Shelton D, Wright WE, Shay JW.

Methods Mol Biol. 2018;1768:513-529. doi: 10.1007/978-1-4939-7778-9_29.


Hyperpolarizability and Operational Magic Wavelength in an Optical Lattice Clock.

Brown RC, Phillips NB, Beloy K, McGrew WF, Schioppo M, Fasano RJ, Milani G, Zhang X, Hinkley N, Leopardi H, Yoon TH, Nicolodi D, Fortier TM, Ludlow AD.

Phys Rev Lett. 2017 Dec 22;119(25):253001. doi: 10.1103/PhysRevLett.119.253001. Epub 2017 Dec 19.


Understanding the impact of diet and nutrition on symptoms of Tourette syndrome: A scoping review.

Ludlow AK, Rogers SL.

J Child Health Care. 2018 Mar;22(1):68-83. doi: 10.1177/1367493517748373. Epub 2017 Dec 21. Review.


An exploration of sarcasm detection in children with Attention Deficit Hyperactivity Disorder.

Ludlow AK, Chadwick E, Morey A, Edwards R, Gutierrez R.

J Commun Disord. 2017 Nov;70:25-34. doi: 10.1016/j.jcomdis.2017.10.003. Epub 2017 Oct 31.


Differential KrasV12 protein levels control a switch regulating lung cancer cell morphology and motility.

Schäfer C, Mohan A, Burford W, Driscoll MK, Ludlow AT, Wright WE, Shay JW, Danuser G.

Converg Sci Phys Oncol. 2016 Sep;2(3):035004. doi: 10.1088/2057-1739/2/3/035004. Epub 2016 Sep 20.


The Maintenance of Telomere Length in CD28+ T Cells During T Lymphocyte Stimulation.

Huang EE, Tedone E, O'Hara R, Cornelius C, Lai TP, Ludlow A, Wright WE, Shay JW.

Sci Rep. 2017 Jul 28;7(1):6785. doi: 10.1038/s41598-017-05174-7.


Mass-Discrepancy Acceleration Relation: A Natural Outcome of Galaxy Formation in Cold Dark Matter Halos.

Ludlow AD, Benítez-Llambay A, Schaller M, Theuns T, Frenk CS, Bower R, Schaye J, Crain RA, Navarro JF, Fattahi A, Oman KA.

Phys Rev Lett. 2017 Apr 21;118(16):161103. doi: 10.1103/PhysRevLett.118.161103. Epub 2017 Apr 21.


Erratum to: ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling.

Gelsomino L, Gu G, Rechoum Y, Beyer AR, Pejerrey SM, Tsimelzon A, Wang T, Huffman K, Ludlow A, Andò S, Fuqua SAW.

Breast Cancer Res Treat. 2017 Jun;163(3):639-640. doi: 10.1007/s10549-017-4250-4. No abstract available.


Compact, thermal-noise-limited reference cavity for ultra-low-noise microwave generation.

Davila-Rodriguez J, Baynes FN, Ludlow AD, Fortier TM, Leopardi H, Diddams SA, Quinlan F.

Opt Lett. 2017 Apr 1;42(7):1277-1280. doi: 10.1364/OL.42.001277.


The role of motion and intensity in deaf children's recognition of real human facial expressions of emotion.

Jones AC, Gutierrez R, Ludlow AK.

Cogn Emot. 2018 Feb;32(1):102-115. doi: 10.1080/02699931.2017.1289894. Epub 2017 Feb 14.


Acute exercise activates p38 MAPK and increases the expression of telomere-protective genes in cardiac muscle.

Ludlow AT, Gratidão L, Ludlow LW, Spangenburg EE, Roth SM.

Exp Physiol. 2017 Apr 1;102(4):397-410. doi: 10.1113/EP086189. Epub 2017 Mar 14.


c9orf72 Disease-Related Foci Are Each Composed of One Mutant Expanded Repeat RNA.

Liu J, Hu J, Ludlow AT, Pham JT, Shay JW, Rothstein JD, Corey DR.

Cell Chem Biol. 2017 Feb 16;24(2):141-148. doi: 10.1016/j.chembiol.2016.12.018. Epub 2017 Jan 26.


Regulation of the Human Telomerase Gene TERT by Telomere Position Effect-Over Long Distances (TPE-OLD): Implications for Aging and Cancer.

Kim W, Ludlow AT, Min J, Robin JD, Stadler G, Mender I, Lai TP, Zhang N, Wright WE, Shay JW.

PLoS Biol. 2016 Dec 15;14(12):e2000016. doi: 10.1371/journal.pbio.2000016. eCollection 2016 Dec.


A qualitative exploration of the daily experiences and challenges faced by parents and caregivers of children with Tourette's syndrome.

Ludlow AK, Brown R, Schulz J.

J Health Psychol. 2018 Dec;23(14):1790-1799. doi: 10.1177/1359105316669878. Epub 2016 Sep 28.


Atypical Sensory behaviours in children with Tourette's Syndrome and in children with Autism Spectrum Disorders.

Ludlow AK, Wilkins AJ.

Res Dev Disabil. 2016 Sep;56:108-16. doi: 10.1016/j.ridd.2016.05.019. Epub 2016 Jun 7.


ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling.

Gelsomino L, Gu G, Rechoum Y, Beyer AR, Pejerrey SM, Tsimelzon A, Wang T, Huffman K, Ludlow A, Andò S, Fuqua SAW.

Breast Cancer Res Treat. 2016 Jun;157(2):253-265. doi: 10.1007/s10549-016-3829-5. Epub 2016 May 13. Erratum in: Breast Cancer Res Treat. 2017 Jun;163(3):639-640.


Comparison of DNA Quantification Methods for Next Generation Sequencing.

Robin JD, Ludlow AT, LaRanger R, Wright WE, Shay JW.

Sci Rep. 2016 Apr 6;6:24067. doi: 10.1038/srep24067.


Replication study of the vitamin D receptor (VDR) genotype association with skeletal muscle traits and sarcopenia.

Walsh S, Ludlow AT, Metter EJ, Ferrucci L, Roth SM.

Aging Clin Exp Res. 2016 Jun;28(3):435-42. doi: 10.1007/s40520-015-0447-8. Epub 2015 Sep 28.


SORBS2 transcription is activated by telomere position effect-over long distance upon telomere shortening in muscle cells from patients with facioscapulohumeral dystrophy.

Robin JD, Ludlow AT, Batten K, Gaillard MC, Stadler G, Magdinier F, Wright WE, Shay JW.

Genome Res. 2015 Dec;25(12):1781-90. doi: 10.1101/gr.190660.115. Epub 2015 Sep 10.


Confronting the language barrier: Theory of mind in deaf children.

Jones AC, Gutierrez R, Ludlow AK.

J Commun Disord. 2015 Jul-Aug;56:47-58. doi: 10.1016/j.jcomdis.2015.06.005. Epub 2015 Jul 2.


Visual performance and the use of colored filters in children who are deaf.

Hollingsworth RS, Ludlow AK, Wilkins AJ, Calver RI, Allen PM.

Optom Vis Sci. 2015 Jun;92(6):690-9. doi: 10.1097/OPX.0000000000000595.


Telomerase reverse transcriptase expression protects transformed human cells against DNA-damaging agents, and increases tolerance to chromosomal instability.

Fleisig HB, Hukezalie KR, Thompson CA, Au-Yeung TT, Ludlow AT, Zhao CR, Wong JM.

Oncogene. 2016 Jan 14;35(2):218-27. doi: 10.1038/onc.2015.75. Epub 2015 Apr 20.


Atomic clock with 1×10(-18) room-temperature blackbody Stark uncertainty.

Beloy K, Hinkley N, Phillips NB, Sherman JA, Schioppo M, Lehman J, Feldman A, Hanssen LM, Oates CW, Ludlow AD.

Phys Rev Lett. 2014 Dec 31;113(26):260801. Epub 2014 Dec 24.


Telomere position effect: regulation of gene expression with progressive telomere shortening over long distances.

Robin JD, Ludlow AT, Batten K, Magdinier F, Stadler G, Wagner KR, Shay JW, Wright WE.

Genes Dev. 2014 Nov 15;28(22):2464-76. doi: 10.1101/gad.251041.114.


Quantitative telomerase enzyme activity determination using droplet digital PCR with single cell resolution.

Ludlow AT, Robin JD, Sayed M, Litterst CM, Shelton DN, Shay JW, Wright WE.

Nucleic Acids Res. 2014 Jul;42(13):e104. doi: 10.1093/nar/gku439. Epub 2014 May 26.


State-of-the-art RF signal generation from optical frequency division.

Hati A, Nelson CW, Barnes C, Lirette D, Fortier T, Quinlan F, DeSalvo JA, Ludlow A, Diddams SA, Howe DA.

IEEE Trans Ultrason Ferroelectr Freq Control. 2013 Sep;60(9):1796-803. doi: 10.1109/TUFFC.2013.2765.


Auditory processing and sensory behaviours in children with autism spectrum disorders as revealed by mismatch negativity.

Ludlow A, Mohr B, Whitmore A, Garagnani M, Pulvermüller F, Gutierrez R.

Brain Cogn. 2014 Apr;86:55-63. doi: 10.1016/j.bandc.2014.01.016. Epub 2014 Feb 22.


Do telomeres adapt to physiological stress? Exploring the effect of exercise on telomere length and telomere-related proteins.

Ludlow AT, Ludlow LW, Roth SM.

Biomed Res Int. 2013;2013:601368. doi: 10.1155/2013/601368. Epub 2013 Dec 24. Review.


Telomeres shorten in response to oxidative stress in mouse skeletal muscle fibers.

Ludlow AT, Spangenburg EE, Chin ER, Cheng WH, Roth SM.

J Gerontol A Biol Sci Med Sci. 2014 Jul;69(7):821-30. doi: 10.1093/gerona/glt211. Epub 2014 Jan 13.


Visual performance and ocular abnormalities in deaf children and young adults: a literature review.

Hollingsworth R, Ludlow AK, Wilkins A, Calver R, Allen PM.

Acta Ophthalmol. 2014 Jun;92(4):305-10. doi: 10.1111/aos.12302. Epub 2013 Dec 13. Review.


An atomic clock with 10(-18) instability.

Hinkley N, Sherman JA, Phillips NB, Schioppo M, Lemke ND, Beloy K, Pizzocaro M, Oates CW, Ludlow AD.

Science. 2013 Sep 13;341(6151):1215-8. doi: 10.1126/science.1240420. Epub 2013 Aug 22.


Sex-specific effects of exercise ancestry on metabolic, morphological and gene expression phenotypes in multiple generations of mouse offspring.

Guth LM, Ludlow AT, Witkowski S, Marshall MR, Lima LC, Venezia AC, Xiao T, Ting Lee ML, Spangenburg EE, Roth SM.

Exp Physiol. 2013 Oct;98(10):1469-84. doi: 10.1113/expphysiol.2012.070300. Epub 2013 Jun 14.


Color obsessions and phobias in autism spectrum disorders: the case of J.G.

Ludlow AK, Heaton P, Hill E, Franklin A.

Neurocase. 2014 Jun;20(3):296-306. doi: 10.1080/13554794.2013.770880. Epub 2013 Apr 3.


Exercise alters mRNA expression of telomere-repeat binding factor 1 in skeletal muscle via p38 MAPK.

Ludlow AT, Lima LC, Wang J, Hanson ED, Guth LM, Spangenburg EE, Roth SM.

J Appl Physiol (1985). 2012 Dec 1;113(11):1737-46. doi: 10.1152/japplphysiol.00200.2012. Epub 2012 Oct 4.


High-accuracy measurement of atomic polarizability in an optical lattice clock.

Sherman JA, Lemke ND, Hinkley N, Pizzocaro M, Fox RW, Ludlow AD, Oates CW.

Phys Rev Lett. 2012 Apr 13;108(15):153002. Epub 2012 Apr 13.


Coloured filters enhance the visual perception of social cues in children with autism spectrum disorders.

Ludlow AK, Taylor-Whiffen E, Wilkins AJ.

ISRN Neurol. 2012;2012:298098. doi: 10.5402/2012/298098. Epub 2012 Mar 4.


Chronic exercise modifies age-related telomere dynamics in a tissue-specific fashion.

Ludlow AT, Witkowski S, Marshall MR, Wang J, Lima LC, Guth LM, Spangenburg EE, Roth SM.

J Gerontol A Biol Sci Med Sci. 2012 Sep;67(9):911-26. doi: 10.1093/gerona/gls002. Epub 2012 Mar 1.

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