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Items: 17

1.

Design, synthesis and biological evaluation of 3-hydroxyquinazoline-2,4(1H,3H)-diones as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and integrase.

Gao P, Cheng X, Sun L, Song S, Álvarez M, Luczkowiak J, Pannecouque C, De Clercq E, Menéndez-Arias L, Zhan P, Liu X.

Bioorg Med Chem. 2019 Sep 1;27(17):3836-3845. doi: 10.1016/j.bmc.2019.07.011. Epub 2019 Jul 6.

PMID:
31324562
2.

Correction to Unprecedented Thiacalixarene Fucoclusters as Strong Inhibitors of Ebola cis-Cell Infection and HCMV-gB Glycoprotein/DC-SIGN C-type Lectin Interaction.

Taouai M, Porkolab V, Chakroun K, Cheneau C, Luczkowiak J, Abidi R, Lesur D, Cragg PJ, Halary F, Delgado R, Fieschi F, Benazza M.

Bioconjug Chem. 2019 Jun 19;30(6):1830-1831. doi: 10.1021/acs.bioconjchem.9b00300. Epub 2019 May 10. No abstract available.

PMID:
31074621
3.

Unprecedented Thiacalixarene Fucoclusters as Strong Inhibitors of Ebola cis-Cell Infection and HCMV-gB Glycoprotein/DC-SIGN C-type Lectin Interaction.

Taouai M, Porkolab V, Chakroun K, Cheneau C, Luczkowiak J, Abidi R, Lesur D, Cragg PJ, Halary F, Delgado R, Fieschi F, Benazza M.

Bioconjug Chem. 2019 Apr 17;30(4):1114-1126. doi: 10.1021/acs.bioconjchem.9b00066. Epub 2019 Apr 4. Erratum in: Bioconjug Chem. 2019 Jun 19;30(6):1830-1831.

PMID:
30912645
4.

Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV-1 RNase H inhibitors.

Gao P, Wang X, Sun L, Cheng X, Poongavanam V, Kongsted J, Álvarez M, Luczkowiak J, Pannecouque C, De Clercq E, Lee KH, Chen CH, Liu H, Menéndez-Arias L, Liu X, Zhan P.

Chem Biol Drug Des. 2019 Apr;93(4):582-589. doi: 10.1111/cbdd.13455. Epub 2019 Jan 24.

PMID:
30560566
5.

Nanocarbon-Based Glycoconjugates as Multivalent Inhibitors of Ebola Virus Infection.

Rodríguez-Pérez L, Ramos-Soriano J, Pérez-Sánchez A, Illescas BM, Muñoz A, Luczkowiak J, Lasala F, Rojo J, Delgado R, Martín N.

J Am Chem Soc. 2018 Aug 8;140(31):9891-9898. doi: 10.1021/jacs.8b03847. Epub 2018 Jul 30.

PMID:
30014698
6.

Template-primer binding affinity and RNase H cleavage specificity contribute to the strand transfer efficiency of HIV-1 reverse transcriptase.

Luczkowiak J, Matamoros T, Menéndez-Arias L.

J Biol Chem. 2018 Aug 31;293(35):13351-13363. doi: 10.1074/jbc.RA118.004324. Epub 2018 Jul 10.

7.

Broad Neutralizing Activity Against Ebolaviruses Lacking the Mucin-Like Domain in Convalescent Plasma Specimens From Patients With Ebola Virus Disease.

Luczkowiak J, Lasala F, Mora-Rillo M, Arribas JR, Delgado R.

J Infect Dis. 2018 Nov 22;218(suppl_5):S574-S581. doi: 10.1093/infdis/jiy302.

8.

Convalescent Plasma for Ebola Virus Disease.

Arribas JR, Luczkowiak J, Delgado R.

N Engl J Med. 2016 Jun 23;374(25):2498-9. doi: 10.1056/NEJMc1602284. No abstract available.

PMID:
27332914
9.

Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection.

Muñoz A, Sigwalt D, Illescas BM, Luczkowiak J, Rodríguez-Pérez L, Nierengarten I, Holler M, Remy JS, Buffet K, Vincent SP, Rojo J, Delgado R, Nierengarten JF, Martín N.

Nat Chem. 2016 Jan;8(1):50-7.

PMID:
27055288
10.

Specific neutralizing response in plasma from convalescent patients of Ebola Virus Disease against the West Africa Makona variant of Ebola virus.

Luczkowiak J, Arribas JR, Gómez S, Jiménez-Yuste V, de la Calle F, Viejo A, Delgado R.

Virus Res. 2016 Feb 2;213:224-229. doi: 10.1016/j.virusres.2015.12.019. Epub 2015 Dec 29.

PMID:
26739425
11.

Glycofullerenes inhibit viral infection.

Luczkowiak J, Muñoz A, Sánchez-Navarro M, Ribeiro-Viana R, Ginieis A, Illescas BM, Martín N, Delgado R, Rojo J.

Biomacromolecules. 2013 Feb 11;14(2):431-7. doi: 10.1021/bm3016658. Epub 2013 Jan 10.

PMID:
23281578
12.

Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection.

Ribeiro-Viana R, Sánchez-Navarro M, Luczkowiak J, Koeppe JR, Delgado R, Rojo J, Davis BG.

Nat Commun. 2012;3:1303. doi: 10.1038/ncomms2302. Erratum in: Nat Commun. 2013;4:1459.

13.

Lack of the detection of XMRV or polytropic MLV-related sequences in blood cells from HIV-1-infected patients in Spain.

Luczkowiak J, Martínez-Prats L, Sierra O, Fiorante S, Rubio R, Pulido F, Otero JR, Delgado R.

J Acquir Immune Defic Syndr. 2012 Feb 1;59(2):101-4. doi: 10.1097/QAI.0b013e318238b596.

PMID:
21963942
14.

Pseudosaccharide functionalized dendrimers as potent inhibitors of DC-SIGN dependent Ebola pseudotyped viral infection.

Luczkowiak J, Sattin S, Sutkevičiūtė I, Reina JJ, Sánchez-Navarro M, Thépaut M, Martínez-Prats L, Daghetti A, Fieschi F, Delgado R, Bernardi A, Rojo J.

Bioconjug Chem. 2011 Jul 20;22(7):1354-65. doi: 10.1021/bc2000403. Epub 2011 Jun 20.

PMID:
21650462
15.

No xenotropic murine leukemia virus-related virus detected in fibromyalgia patients.

Luczkowiak J, Sierra O, González-Martín JJ, Herrero-Beaumont G, Delgado R.

Emerg Infect Dis. 2011 Feb;17(2):314-5. doi: 10.3201/eid1702.100978. No abstract available.

16.

Sustained profile of transmitted drug resistance mutations for more than 10 years in an HIV type 1-infected patient.

Martínez-Prats L, Luczkowiak J, Gutiérrez F, Zurita S, Fiorante S, Llenas-García J, Pulido F, Delgado R.

AIDS Res Hum Retroviruses. 2011 Jan;27(1):41-5. doi: 10.1089/aid.2010.0104. Epub 2010 Oct 4.

PMID:
20919922
17.

Detection of HIV-1 at between 20 and 49 copies per milliliter by the Cobas TaqMan HIV-1 v2.0 assay is associated with higher pretherapy viral load and less time on antiretroviral therapy.

Pascual-Pareja JF, Martínez-Prats L, Luczkowiak J, Fiorante S, Rubio R, Pulido F, Otero JR, Delgado R.

J Clin Microbiol. 2010 May;48(5):1911-2. doi: 10.1128/JCM.02388-09. Epub 2010 Feb 24.

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