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Items: 14

1.

RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-xL in developing thymocytes.

Ligons DL, Hwang S, Waickman AT, Park JY, Luckey MA, Park JH.

Sci Signal. 2018 Aug 28;11(545). pii: eaam8939. doi: 10.1126/scisignal.aam8939.

PMID:
30154103
2.

IL-7-dependent STAT1 activation limits homeostatic CD4+ T cell expansion.

Le Saout C, Luckey MA, Villarino AV, Smith M, Hasley RB, Myers TG, Imamichi H, Park JH, O'Shea JJ, Lane HC, Catalfamo M.

JCI Insight. 2017 Nov 16;2(22). pii: 96228. doi: 10.1172/jci.insight.96228. eCollection 2017 Nov 16.

3.

Soluble γc cytokine receptor suppresses IL-15 signaling and impairs iNKT cell development in the thymus.

Park JY, Jo Y, Ko E, Luckey MA, Park YK, Park SH, Park JH, Hong C.

Sci Rep. 2016 Nov 11;6:36962. doi: 10.1038/srep36962.

4.

Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation.

Hong C, Luckey MA, Ligons DL, Waickman AT, Park JY, Kim GY, Keller HR, Etzensperger R, Tai X, Lazarevic V, Feigenbaum L, Catalfamo M, Walsh ST, Park JH.

Immunity. 2014 Jun 19;40(6):910-23. doi: 10.1016/j.immuni.2014.04.020. Epub 2014 Jun 5.

5.

The transcription factor ThPOK suppresses Runx3 and imposes CD4(+) lineage fate by inducing the SOCS suppressors of cytokine signaling.

Luckey MA, Kimura MY, Waickman AT, Feigenbaum L, Singer A, Park JH.

Nat Immunol. 2014 Jul;15(7):638-45. doi: 10.1038/ni.2917. Epub 2014 Jun 1.

6.

Chronic exposure to type-I IFN under lymphopenic conditions alters CD4 T cell homeostasis.

Le Saout C, Hasley RB, Imamichi H, Tcheung L, Hu Z, Luckey MA, Park JH, Durum SK, Smith M, Rupert AW, Sneller MC, Lane HC, Catalfamo M.

PLoS Pathog. 2014 Mar 6;10(3):e1003976. doi: 10.1371/journal.ppat.1003976. eCollection 2014 Mar.

7.

Interleukin-6 expands homeostatic space for peripheral T cells.

Hong C, Nam AS, Keller HR, Ligons DL, Park JY, Yoon HW, Park JJ, Luckey MA, Park JH.

Cytokine. 2013 Nov;64(2):532-40. doi: 10.1016/j.cyto.2013.08.001. Epub 2013 Aug 26.

8.

Ikaros is required to survive positive selection and to maintain clonal diversity during T-cell development in the thymus.

Tinsley KW, Hong C, Luckey MA, Park JY, Kim GY, Yoon HW, Keller HR, Sacks AJ, Feigenbaum L, Park JH.

Blood. 2013 Oct 3;122(14):2358-68. doi: 10.1182/blood-2012-12-472076. Epub 2013 Aug 1.

9.

Metabolic sensor AMPK directly phosphorylates RAG1 protein and regulates V(D)J recombination.

Um JH, Brown AL, Singh SK, Chen Y, Gucek M, Lee BS, Luckey MA, Kim MK, Park JH, Sleckman BP, Gellert M, Chung JH.

Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9873-8. doi: 10.1073/pnas.1307928110. Epub 2013 May 28.

10.

Pim1 permits generation and survival of CD4+ T cells in the absence of γc cytokine receptor signaling.

Linowes BA, Ligons DL, Nam AS, Hong C, Keller HR, Tai X, Luckey MA, Park JH.

Eur J Immunol. 2013 Sep;43(9):2283-94. doi: 10.1002/eji.201242686. Epub 2013 Jun 21.

11.

γc Cytokine signaling: graduate school in thymic education.

Luckey MA, Park JH.

Blood. 2013 Jan 3;121(1):4-6. doi: 10.1182/blood-2012-10-461525. No abstract available.

PMID:
23287622
12.

CD8 lineage-specific regulation of interleukin-7 receptor expression by the transcriptional repressor Gfi1.

Ligons DL, Tuncer C, Linowes BA, Akcay IM, Kurtulus S, Deniz E, Atasever Arslan B, Cevik SI, Keller HR, Luckey MA, Feigenbaum L, Möröy T, Ersahin T, Atalay R, Erman B, Park JH.

J Biol Chem. 2012 Oct 5;287(41):34386-99. doi: 10.1074/jbc.M112.378687. Epub 2012 Aug 3.

13.

An in vivo IL-7 requirement for peripheral Foxp3+ regulatory T cell homeostasis.

Kim GY, Ligons DL, Hong C, Luckey MA, Keller HR, Tai X, Lucas PJ, Gress RE, Park JH.

J Immunol. 2012 Jun 15;188(12):5859-66. doi: 10.4049/jimmunol.1102328. Epub 2012 May 16.

14.

Intrathymic IL-7: the where, when, and why of IL-7 signaling during T cell development.

Hong C, Luckey MA, Park JH.

Semin Immunol. 2012 Jun;24(3):151-8. doi: 10.1016/j.smim.2012.02.002. Epub 2012 Mar 14. Review.

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