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Items: 10

1.

Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole.

Luckert C, Braeuning A, de Sousa G, Durinck S, Katsanou ES, Konstantinidou P, Machera K, Milani ES, Peijnenburg AACM, Rahmani R, Rajkovic A, Rijkers D, Spyropoulou A, Stamou M, Stoopen G, Sturla S, Wollscheid B, Zucchini-Pascal N, Lampen A.

Chem Res Toxicol. 2018 Jul 11. doi: 10.1021/acs.chemrestox.8b00112. [Epub ahead of print]

PMID:
29995386
2.

PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids.

Luckert C, Braeuning A, Lampen A, Hessel-Pras S.

Chem Biol Interact. 2018 May 25;288:38-48. doi: 10.1016/j.cbi.2018.04.017. Epub 2018 Apr 14.

PMID:
29665350
3.

Regulation of Drug Metabolism by the Interplay of Inflammatory Signaling, Steatosis, and Xeno-Sensing Receptors in HepaRG Cells.

Tanner N, Kubik L, Luckert C, Thomas M, Hofmann U, Zanger UM, Böhmert L, Lampen A, Braeuning A.

Drug Metab Dispos. 2018 Apr;46(4):326-335. doi: 10.1124/dmd.117.078675. Epub 2018 Jan 12.

PMID:
29330220
4.

Comparative analysis of 3D culture methods on human HepG2 cells.

Luckert C, Schulz C, Lehmann N, Thomas M, Hofmann U, Hammad S, Hengstler JG, Braeuning A, Lampen A, Hessel S.

Arch Toxicol. 2017 Jan;91(1):393-406. doi: 10.1007/s00204-016-1677-z. Epub 2016 Feb 12.

PMID:
26872951
5.

Utility of an appropriate reporter assay: Heliotrine interferes with GAL4/upstream activation sequence-driven reporter gene systems.

Luckert C, Hessel S, Lampen A, Braeuning A.

Anal Biochem. 2015 Oct 15;487:45-8. doi: 10.1016/j.ab.2015.07.009. Epub 2015 Jul 26.

PMID:
26212314
6.

Disturbance of gene expression in primary human hepatocytes by hepatotoxic pyrrolizidine alkaloids: A whole genome transcriptome analysis.

Luckert C, Hessel S, Lenze D, Lampen A.

Toxicol In Vitro. 2015 Oct;29(7):1669-82. doi: 10.1016/j.tiv.2015.06.021. Epub 2015 Jun 20.

PMID:
26100227
7.

Dose-dependent induction of signaling pathways by the flavonoid quercetin in human primary hepatocytes: A transcriptomic study.

Waizenegger J, Lenze D, Luckert C, Seidel A, Lampen A, Hessel S.

Mol Nutr Food Res. 2015 Jun;59(6):1117-29. doi: 10.1002/mnfr.201400764. Epub 2015 May 5.

PMID:
25788151
8.

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells.

Eschenburg G, Luckert C, Reinshagen K, Bergholz R.

Genes Cancer. 2014 Nov;5(11-12):460-9.

9.

Taurolidine specifically inhibits growth of neuroblastoma cell lines in vitro.

Luckert C, Eschenburg G, Roth B, Appl B, Reinshagen K, Bergholz R.

J Pediatr Hematol Oncol. 2014 May;36(4):e219-23. doi: 10.1097/MPH.0000000000000149.

PMID:
24762556
10.

Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR.

Luckert C, Ehlers A, Buhrke T, Seidel A, Lampen A, Hessel S.

Toxicol Lett. 2013 Oct 24;222(2):180-8. doi: 10.1016/j.toxlet.2013.06.243. Epub 2013 Jul 8.

PMID:
23845848

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