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Structural organization of lipid-functionalized-Au nanoparticles.

Luchini A, D'Errico G, Leone S, Vaezi Z, Bortolotti A, Stella L, Vitiello G, Paduano L.

Colloids Surf B Biointerfaces. 2018 Aug 1;168:2-9. doi: 10.1016/j.colsurfb.2018.04.044. Epub 2018 Apr 24.


Affinity enrichment for mass spectrometry: improving the yield of low abundance biomarkers.

Kim B, Araujo R, Howard M, Magni R, Liotta LA, Luchini A.

Expert Rev Proteomics. 2018 Apr;15(4):353-366. doi: 10.1080/14789450.2018.1450631. Epub 2018 Mar 22.


The impact of deuteration on natural and synthetic lipids: A neutron diffraction study.

Luchini A, Delhom R, Demé B, Laux V, Moulin M, Haertlein M, Pichler H, Strohmeier GA, Wacklin H, Fragneto G.

Colloids Surf B Biointerfaces. 2018 Aug 1;168:126-133. doi: 10.1016/j.colsurfb.2018.02.009. Epub 2018 Feb 5.


Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity.

Paris L, Magni R, Zaidi F, Araujo R, Saini N, Harpole M, Coronel J, Kirwan DE, Steinberg H, Gilman RH, Petricoin EF 3rd, Nisini R, Luchini A, Liotta L.

Sci Transl Med. 2017 Dec 13;9(420). pii: eaal2807. doi: 10.1126/scitranslmed.aal2807.


Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine.

Waldie S, Lind TK, Browning K, Moulin M, Haertlein M, Forsyth VT, Luchini A, Strohmeier GA, Pichler H, Maric S, Cárdenas M.

Langmuir. 2018 Jan 9;34(1):472-479. doi: 10.1021/acs.langmuir.7b02716. Epub 2017 Dec 27.


Toward detection of toxoplasmosis from urine in mice using hydro-gel nanoparticles concentration and parallel reaction monitoring mass spectrometry.

Steinberg HE, Russo P, Angulo N, Ynocente R, Montoya C, Diestra A, Ferradas C, Schiaffino F, Florentini E, Jimenez J, Calderón M, Carruthers VB, Gilman RH, Liotta L, Luchini A.

Nanomedicine. 2018 Feb;14(2):461-469. doi: 10.1016/j.nano.2017.11.020. Epub 2017 Dec 1.


IL-1 Family Cytokines Use Distinct Molecular Mechanisms to Signal through Their Shared Co-receptor.

Günther S, Deredge D, Bowers AL, Luchini A, Bonsor DA, Beadenkopf R, Liotta L, Wintrode PL, Sundberg EJ.

Immunity. 2017 Sep 19;47(3):510-523.e4. doi: 10.1016/j.immuni.2017.08.004.


Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread.

Spreafico F, Bongarzone I, Pizzamiglio S, Magni R, Taverna E, De Bortoli M, Ciniselli CM, Barzanò E, Biassoni V, Luchini A, Liotta LA, Zhou W, Signore M, Verderio P, Massimino M.

Oncotarget. 2017 Jul 11;8(28):46177-46190. doi: 10.18632/oncotarget.17579.


Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers.

Magni R, Luchini A.

Methods Mol Biol. 2017;1606:103-113. doi: 10.1007/978-1-4939-6990-6_7.


Structure and dynamics of cetyltrimethylammonium chloride-sodium dodecylsulfate (CTAC-SDS) catanionic vesicles: High-value nano-vehicles from low-cost surfactants.

Russo Krauss I, Imperatore R, De Santis A, Luchini A, Paduano L, D'Errico G.

J Colloid Interface Sci. 2017 Sep 1;501:112-122. doi: 10.1016/j.jcis.2017.04.032. Epub 2017 Apr 12.


Antiproliferative effects of ruthenium-based nucleolipidic nanoaggregates in human models of breast cancer in vitro: insights into their mode of action.

Irace C, Misso G, Capuozzo A, Piccolo M, Riccardi C, Luchini A, Caraglia M, Paduano L, Montesarchio D, Santamaria R.

Sci Rep. 2017 Mar 28;7:45236. doi: 10.1038/srep45236.


Neutron Reflectometry reveals the interaction between functionalized SPIONs and the surface of lipid bilayers.

Luchini A, Gerelli Y, Fragneto G, Nylander T, Pálsson GK, Appavou MS, Paduano L.

Colloids Surf B Biointerfaces. 2017 Mar 1;151:76-87. doi: 10.1016/j.colsurfb.2016.12.005. Epub 2016 Dec 7.


Functionalized SPIONs: the surfactant nature modulates the self-assembly and cluster formation.

Luchini A, Heenan RK, Paduano L, Vitiello G.

Phys Chem Chem Phys. 2016 Jul 21;18(27):18441-9. doi: 10.1039/c6cp01694d. Epub 2016 Jun 24.


Use of a Chagas Urine Nanoparticle Test (Chunap) to Correlate with Parasitemia Levels in T. cruzi/HIV Co-infected Patients.

Castro-Sesquen YE, Gilman RH, Mejia C, Clark DE, Choi J, Reimer-McAtee MJ, Castro R, Valencia-Ayala E, Flores J, Bowman N, Castillo-Neyra R, Torrico F, Liotta L, Bern C, Luchini A; Chagas/HIV Working Group in Bolivia and Peru.

PLoS Negl Trop Dis. 2016 Feb 26;10(2):e0004407. doi: 10.1371/journal.pntd.0004407. eCollection 2016 Feb.


Class I Hydrophobin Vmh2 Adopts Atypical Mechanisms to Self-Assemble into Functional Amyloid Fibrils.

Gravagnuolo AM, Longobardi S, Luchini A, Appavou MS, De Stefano L, Notomista E, Paduano L, Giardina P.

Biomacromolecules. 2016 Mar 14;17(3):954-64. doi: 10.1021/acs.biomac.5b01632. Epub 2016 Feb 12.


Phosphocholine-decorated superparamagnetic iron oxide nanoparticles: defining the structure and probing in vivo applications.

Luchini A, Irace C, Santamaria R, Montesarchio D, Heenan RK, Szekely N, Flori A, Menichetti L, Paduano L.

Nanoscale. 2016 May 21;8(19):10078-86. doi: 10.1039/c5nr08486e. Epub 2016 Jan 11.


Identification of novel candidate circulating biomarkers for malignant soft tissue sarcomas: Correlation with metastatic progression.

Conti A, Fredolini C, Tamburro D, Magagnoli G, Zhou W, Liotta LA, Picci P, Luchini A, Benassi MS.

Proteomics. 2016 Feb;16(4):689-97. doi: 10.1002/pmic.201500164.


Application of Nanotrap technology for high sensitivity measurement of urinary outer surface protein A carboxyl-terminus domain in early stage Lyme borreliosis.

Magni R, Espina BH, Shah K, Lepene B, Mayuga C, Douglas TA, Espina V, Rucker S, Dunlap R, Petricoin EF, Kilavos MF, Poretz DM, Irwin GR, Shor SM, Liotta LA, Luchini A.

J Transl Med. 2015 Nov 4;13:346. doi: 10.1186/s12967-015-0701-z.


Unlocking the secrets to protein-protein interface drug targets using structural mass spectrometry techniques.

Dailing A, Luchini A, Liotta L.

Expert Rev Proteomics. 2015;12(5):457-67. doi: 10.1586/14789450.2015.1079487. Epub 2015 Sep 1. Review.


Thymosin α 1 potentiates the release by CD8(+) cells of soluble factors able to inhibit HIV-1 and human T lymphotropic virus 1 infection in vitro.

Matteucci C, Minutolo A, Pollicita M, Balestrieri E, Grelli S, D'Ettorre G, Vullo V, Bucci I, Luchini A, Aquaro S, Sinibaldi-Vallebona P, Macchi B, Perno CF, Mastino A, Garaci E.

Expert Opin Biol Ther. 2015;15 Suppl 1:S83-100. doi: 10.1517/14712598.2015.1021677. Epub 2015 Jun 22.


Chemokine-Releasing Nanoparticles for Manipulation of Lymph Node Microenvironment.

Popova TG, Teunis A, Magni R, Luchini A, Espina V, Liotta LA, Popov SG.

Nanomaterials (Basel). 2015 Mar;5(1):298-320.


Developing functionalized Fe3O4-Au nanoparticles: a physico-chemical insight.

Luchini A, Vitiello G, Rossi F, Ruiz De Ballesteros O, Radulescu A, D'Errico G, Montesarchio D, de Julián Fernández C, Paduano L.

Phys Chem Chem Phys. 2015 Feb 28;17(8):6087-97. doi: 10.1039/c4cp05854b.


Expression of TNF-α and IL-6 cytokines in the choroid and sclera of hypercholesterolemic rabbits.

Torres RJ, Luchini A, Barberini LY, Precoma L, Torres CL, Torres RA, Noronha Ld, Erbano BO, Casella AM, Precoma DB.

Arq Bras Oftalmol. 2014 May-Jun;77(3):168-72.


Use of a novel chagas urine nanoparticle test (chunap) for diagnosis of congenital chagas disease.

Castro-Sesquen YE, Gilman RH, Galdos-Cardenas G, Ferrufino L, Sánchez G, Valencia Ayala E, Liotta L, Bern C, Luchini A; Working Group on Chagas Disease in Bolivia and Peru.

PLoS Negl Trop Dis. 2014 Oct 2;8(10):e3211. doi: 10.1371/journal.pntd.0003211. eCollection 2014 Oct.


Effect of flaxseed on choroid-sclera complex thickness and on LDL oxidation in the sclera, choroid and retina of diet-induced hypercholesterolaemic rabbits.

Torres RJ, Luchini A, Both AS, Precoma LB, Champoski AF, Schuh ML, Torres RP, Noronha L, Pessoa BM, Torres LA, Serci NF, Precoma DB.

Br J Nutr. 2014 Nov 14;112(9):1438-46. doi: 10.1017/S0007114514002463. Epub 2014 Sep 23.


Hydrogel nanoparticle harvesting of plasma or urine for detecting low abundance proteins.

Magni R, Espina BH, Liotta LA, Luchini A, Espina V.

J Vis Exp. 2014 Aug 7;(90):e51789. doi: 10.3791/51789.


Tris buffer modulates polydopamine growth, aggregation, and paramagnetic properties.

Della Vecchia NF, Luchini A, Napolitano A, D'Errico G, Vitiello G, Szekely N, d'Ischia M, Paduano L.

Langmuir. 2014 Aug 19;30(32):9811-8. doi: 10.1021/la501560z. Epub 2014 Aug 8.


Protein painting reveals solvent-excluded drug targets hidden within native protein-protein interfaces.

Luchini A, Espina V, Liotta LA.

Nat Commun. 2014 Jul 22;5:4413. doi: 10.1038/ncomms5413.


Effect of candesartan on the expression of sclera-choroidal intercellular adhesion molecule-1 in hypercholesterolemic models.

Torres RJ, Luchini A, Torres Rdo R, Oliveira LR, Torres CL, Torres RA, Olandoski M, Nagashima S, Noronha Ld, Precoma DB.

Clinics (Sao Paulo). 2014 Feb;69(2):145-9. doi: 10.6061/clinics/2014(02)11.


The use of Nanotrap particles for biodefense and emerging infectious disease diagnostics.

Shafagati N, Patanarut A, Luchini A, Lundberg L, Bailey C, Petricoin E 3rd, Liotta L, Narayanan A, Lepene B, Kehn-Hall K.

Pathog Dis. 2014 Jul;71(2):164-76. doi: 10.1111/2049-632X.12136. Epub 2014 Mar 20. Review.


Reactive oxygen species activate NFκB (p65) and p53 and induce apoptosis in RVFV infected liver cells.

Narayanan A, Amaya M, Voss K, Chung M, Benedict A, Sampey G, Kehn-Hall K, Luchini A, Liotta L, Bailey C, Kumar A, Bavari S, Hakami RM, Kashanchi F.

Virology. 2014 Jan 20;449:270-86. doi: 10.1016/j.virol.2013.11.023. Epub 2013 Dec 15.


Antioxidant and intestinal anti-inflammatory effects of plant-derived coumarin derivatives.

Witaicenis A, Seito LN, da Silveira Chagas A, de Almeida LD Jr, Luchini AC, Rodrigues-Orsi P, Cestari SH, Di Stasi LC.

Phytomedicine. 2014 Feb 15;21(3):240-6. doi: 10.1016/j.phymed.2013.09.001. Epub 2013 Oct 28.


Analysis of urinary human growth hormone (hGH) using hydrogel nanoparticles and isoform differential immunoassays after short recombinant hGH treatment: preliminary results.

Bosch J, Luchini A, Pichini S, Tamburro D, Fredolini C, Liotta L, Petricoin E, Pacifici R, Facchiano F, Segura J, Garaci E, Gutiérrez-Gallego R.

J Pharm Biomed Anal. 2013 Nov;85:194-7. doi: 10.1016/j.jpba.2013.07.028. Epub 2013 Aug 1.


[Increased VEGFR-1 immunoreactivity in the choroid-scleral complex in hypercholesterolemia experimental model].

Torres RJ, Noronha Ld, Casella AM, Torres Rdo R, Martins Ide C, Zotz R, Luchini A, Hoffmann Filho CR, Précoma DB.

Arq Bras Oftalmol. 2013 Jan-Feb;76(1):1-5. Portuguese.


Effect of olmesartan on leukocyte recruitment in choroid-sclera complex in hypercholesterolemia model.

Torres RJ, de Noronha L, Casella AM, Grobe SF, Martins Ide C, Torres Rdo R, Luchini A, Sturzeneker MC, Torres CL, Precoma DB.

J Ocul Pharmacol Ther. 2013 Oct;29(8):709-14. doi: 10.1089/jop.2012.0142. Epub 2013 May 17.


Dermatophyte-host relationship of a murine model of experimental invasive dermatophytosis.

Venturini J, Alvares AM, Camargo MR, Marchetti CM, Fraga-Silva TF, Luchini AC, Arruda MS.

Microbes Infect. 2012 Nov;14(13):1144-51. doi: 10.1016/j.micinf.2012.07.014. Epub 2012 Jul 27.


Interlaboratory reproducibility of selective reaction monitoring assays using multiple upfront analyte enrichment strategies.

Prakash A, Rezai T, Krastins B, Sarracino D, Athanas M, Russo P, Zhang H, Tian Y, Li Y, Kulasingam V, Drabovich A, Smith CR, Batruch I, Oran PE, Fredolini C, Luchini A, Liotta L, Petricoin E, Diamandis EP, Chan DW, Nelson R, Lopez MF.

J Proteome Res. 2012 Aug 3;11(8):3986-95. doi: 10.1021/pr300014s. Epub 2012 Jul 3.


[Increase of choroidal and scleral MCP-1 expression in hypercholesterolemia experimental model].

Torres RJ, Noronha Ld, Casella AM, Lumikoski TI, Précoma LB, Torres CL, Luchini A, Sturzeneker MC, Précoma DB.

Arq Bras Oftalmol. 2012 Jan-Feb;75(1):48-52. Portuguese.


Application of Analyte Harvesting Nanoparticle Technology to the Measurement of Urinary HGH in Healthy Individuals.

Luchini A, Tamburro D, Magni R, Fredolini C, Espina V, Bosch J, Garaci E, Petricoin EF 3rd, Liotta LA.

J Sports Med Doping Stud. 2012;2(6). pii: e127.


Suppression of TNBS-induced colitis in rats by 4-methylesculetin, a natural coumarin: comparison with prednisolone and sulphasalazine.

Witaicenis A, Luchini AC, Hiruma-Lima CA, Felisbino SL, Garrido-Mesa N, Utrilla P, Gálvez J, Di Stasi LC.

Chem Biol Interact. 2012 Jan 5;195(1):76-85. doi: 10.1016/j.cbi.2011.11.004. Epub 2011 Nov 16.


Multifunctional core-shell nanoparticles: discovery of previously invisible biomarkers.

Tamburro D, Fredolini C, Espina V, Douglas TA, Ranganathan A, Ilag L, Zhou W, Russo P, Espina BH, Muto G, Petricoin EF 3rd, Liotta LA, Luchini A.

J Am Chem Soc. 2011 Nov 30;133(47):19178-88. doi: 10.1021/ja207515j. Epub 2011 Nov 3.


Cordia verbenacea and secretion of mast cells in different animal species.

de Oliveira DM, Luchini AC, Seito LN, Gomes JC, Crespo-López ME, Di Stasi LC.

J Ethnopharmacol. 2011 May 17;135(2):463-8. doi: 10.1016/j.jep.2011.03.046. Epub 2011 Mar 29.


A novel biomarker harvesting nanotechnology identifies Bak as a candidate melanoma biomarker in serum.

Longo C, Gambara G, Espina V, Luchini A, Bishop B, Patanarut AS, Petricoin EF 3rd, Beretti F, Ferrari B, Garaci E, De Pol A, Pellacani G, Liotta LA.

Exp Dermatol. 2011 Jan;20(1):29-34. doi: 10.1111/j.1600-0625.2010.01187.x.


The use of hydrogel microparticles to sequester and concentrate bacterial antigens in a urine test for Lyme disease.

Douglas TA, Tamburro D, Fredolini C, Espina BH, Lepene BS, Ilag L, Espina V, Petricoin EF 3rd, Liotta LA, Luchini A.

Biomaterials. 2011 Feb;32(4):1157-66. doi: 10.1016/j.biomaterials.2010.10.004. Epub 2010 Oct 28.


Synthesis and characterization of hydrogel particles containing Cibacron Blue F3G-A.

Patanarut A, Luchini A, Botterell PJ, Mohan A, Longo C, Vorster P, Petricoin EF 3rd, Liotta LA, Bishop B.

Colloids Surf A Physicochem Eng Asp. 2010 Jun;362(1-3):8-19.


Sclerochorioretinal abnormalities in hypercholesterolemic rabbits treated with rosiglitazone.

Torres RJ, Muccioli C, Maia M, Noronha L, Luchini A, Alessi A, Olandoski M, Farah ME, Précoma DB.

Ophthalmic Surg Lasers Imaging. 2010 Sep-Oct;41(5):562-71. doi: 10.3928/15428877-20100726-05. Epub 2010 Jul 29.


Nanoparticle technology: Addressing the fundamental roadblocks to protein biomarker discovery.

Luchini A, Longo C, Espina V, Petricoin EF 3rd, Liotta LA.

J Mater Chem. 2009 Aug 7;19(29):5071-5077.


Investigation of the ovarian and prostate cancer peptidome for candidate early detection markers using a novel nanoparticle biomarker capture technology.

Fredolini C, Meani F, Luchini A, Zhou W, Russo P, Ross M, Patanarut A, Tamburro D, Gambara G, Ornstein D, Odicino F, Ragnoli M, Ravaggi A, Novelli F, Collura D, D'Urso L, Muto G, Belluco C, Pecorelli S, Liotta L, Petricoin EF 3rd.

AAPS J. 2010 Dec;12(4):504-18. doi: 10.1208/s12248-010-9211-3. Epub 2010 Jun 12.


Nanoparticle technology: amplifying the effective sensitivity of biomarker detection to create a urine test for hGH.

Fredolini C, Tamburro D, Gambara G, Lepene BS, Espina V, Petricoin EF 3rd, Liotta LA, Luchini A.

Drug Test Anal. 2009 Sep;1(9-10):447-54. doi: 10.1002/dta.96. Review.


Nanoparticle technology: addressing the fundamental roadblocks to protein biomarker discovery.

Luchini A, Fredolini C, Espina BH, Meani F, Reeder A, Rucker S, Petricoin EF 3rd, Liotta LA.

Curr Mol Med. 2010 Mar;10(2):133-41. Review.

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