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Items: 45

1.

Association between ANXA2*5681 polymorphism (rs7170178) and osteonecrosis in haemoglobin SS-genotyped patients.

Pereira-Martins DA, Coelho-Silva JL, Domingos IF, Weinhäuser I, Silveira DR, Cunha AF, Franca-Neto PL, Franca RF, Costa FF, Araújo AS, Lucena-Araujo AR, Bezerra MA.

Br J Haematol. 2019 Nov 11. doi: 10.1111/bjh.16267. [Epub ahead of print] No abstract available.

PMID:
31710691
2.

The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Inflammation in the CNS.

Lima MC, de Mendonça LR, Rezende AM, Carrera RM, Aníbal-Silva CE, Demers M, D'Aiuto L, Wood J, Chowdari KV, Griffiths M, Lucena-Araujo AR, Barral-Netto M, Azevedo EAN, Alves RW, Farias PCS, Marques ETA, Castanha PMS, Donald CL, Kohl A, Nimgaonkar VL, Franca RFO.

Front Immunol. 2019 Aug 16;10:1928. doi: 10.3389/fimmu.2019.01928. eCollection 2019.

3.

Combining gene mutation with gene expression analysis improves outcome prediction in acute promyelocytic leukemia.

Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Silveira DR, Koury LC, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Nunes EC, Fagundes EM, Gloria AB, Kerbauy F, de Lourdes Chauffaille M, Bendit I, Rocha V, Keating A, Tallman MS, Ribeiro RC, Dillon R, Ganser A, Löwenberg B, Valk PJM, Lo-Coco F, Sanz MA, Berliner N, Rego EM.

Blood. 2019 Sep 19;134(12):951-959. doi: 10.1182/blood.2019000239. Epub 2019 Jul 10.

PMID:
31292112
4.

Interaction between hemoglobin S and N-Baltimore: a case report in Pernambuco, Brazil.

Batista THC, Sobreira MJVC, Santana RM, Arcanjo GDS, Ramos CMA, Albuquerque DM, Araujo ADS, Anjos ACMD, Costa FF, Lucena-Araujo AR, Bezerra MAC.

Hematol Transfus Cell Ther. 2019 Oct - Dec;41(4):365-368. doi: 10.1016/j.htct.2019.02.002. Epub 2019 May 12. No abstract available.

5.

PIP4K2A and PIP4K2C transcript levels are associated with cytogenetic risk and survival outcomes in acute myeloid leukemia.

Lima K, Coelho-Silva JL, Kinker GS, Pereira-Martins DA, Traina F, Fernandes PACM, Markus RP, Lucena-Araujo AR, Machado-Neto JA.

Cancer Genet. 2019 Apr;233-234:56-66. doi: 10.1016/j.cancergen.2019.04.002. Epub 2019 Apr 11.

PMID:
31109595
6.

Highlight article: Whole-exome sequencing indicates FLG2 variant associated with leg ulcers in Brazilian sickle cell anemia patients.

de Carvalho-Siqueira GQ, Ananina G, de Souza BB, Borges MG, Ito MT, da Silva-Costa SM, de Farias Domingos I, Falcão DA, Lopes-Cendes I, Bezerra MAC, da Silva Araújo A, Lucena-Araújo AR, de Souza Gonçalves M, Saad STO, Costa FF, de Melo MB.

Exp Biol Med (Maywood). 2019 Aug;244(11):932-939. doi: 10.1177/1535370219849592. Epub 2019 May 12. No abstract available.

PMID:
31079484
7.

Unraveling KDM4 histone demethylase expression and its association with adverse cytogenetic findings in chronic lymphocytic leukemia.

Filiú-Braga LDC, Serejo TRT, Lucena-Araujo AR, Neves FAR, de Carvalho JL, Rego EM, Saldanha-Araujo F.

Med Oncol. 2018 Nov 13;36(1):3. doi: 10.1007/s12032-018-1226-0.

PMID:
30426231
8.

EGFR Exon 20 Insertion Mutations Display Sensitivity to Hsp90 Inhibition in Preclinical Models and Lung Adenocarcinomas.

Jorge SE, Lucena-Araujo AR, Yasuda H, Piotrowska Z, Oxnard GR, Rangachari D, Huberman MS, Sequist LV, Kobayashi SS, Costa DB.

Clin Cancer Res. 2018 Dec 15;24(24):6548-6555. doi: 10.1158/1078-0432.CCR-18-1541. Epub 2018 Aug 28.

PMID:
30154228
9.

Persistent detection of Zika virus RNA from an infant with severe microcephaly - a case report.

Brito CAA, Henriques-Souza A, Soares CRP, Castanha PMS, Machado LC, Pereira MR, Sobral MCM, Lucena-Araujo AR, Wallau GL, Franca RFO.

BMC Infect Dis. 2018 Aug 10;18(1):388. doi: 10.1186/s12879-018-3313-4.

10.

GLP overexpression is associated with poor prognosis in Chronic Lymphocytic Leukemia and its inhibition induces leukemic cell death.

Alves-Silva JC, de Carvalho JL, Rabello DA, Serejo TRT, Rego EM, Neves FAR, Lucena-Araujo AR, Pittella-Silva F, Saldanha-Araujo F.

Invest New Drugs. 2018 Oct;36(5):955-960. doi: 10.1007/s10637-018-0613-x. Epub 2018 May 31.

PMID:
29855824
11.

Clinical impact of BAALC expression in high-risk acute promyelocytic leukemia.

Lucena-Araujo AR, Pereira-Martins DA, Koury LC, Franca-Neto PL, Coelho-Silva JL, de Deus Wagatsuma VM, Melo RAM, Bittencourt R, Pagnano K, Pasquini R, Chiattone CS, Fagundes EM, Chauffaille ML, Schrier SL, Tallman MS, Ribeiro RC, Grimwade D, Ganser A, Löwenberg B, Lo-Coco F, Sanz MA, Berliner N, Rego EM.

Blood Adv. 2017 Sep 15;1(21):1807-1814. doi: 10.1182/bloodadvances.2017005926. eCollection 2017 Sep 26.

12.

Evaluation of the European LeukemiaNet recommendations for predicting outcomes of patients with acute myeloid leukemia treated in low- and middle-income countries (LMIC): A Brazilian experience.

Benicio MTL, Ribeiro AFT, Américo AD, Furtado FM, Glória AB, Lima AS, Santos SM, Xavier SG, Lucena-Araujo AR, Fagundes EM, Rego EM.

Leuk Res. 2017 Sep;60:109-114. doi: 10.1016/j.leukres.2017.07.005. Epub 2017 Jul 24.

PMID:
28777950
13.

Interleukin-6 G-174C polymorphism predicts higher risk of stroke in sickle cell anaemia.

Domingos IF, Pereira-Martins DA, Coelho-Silva JL, Borges-Medeiros RL, Falcão DA, Azevedo RC, Anjos AC, Costa FF, Mendonça TF, Cavalcanti MS, Araujo AS, Lucena-Araujo AR, Bezerra MA.

Br J Haematol. 2018 Jul;182(2):294-297. doi: 10.1111/bjh.14773. Epub 2017 May 23. No abstract available.

PMID:
28542795
14.

ΔNp73 overexpression promotes resistance to apoptosis but does not cooperate with PML/RARA in the induction of an APL-leukemic phenotype.

Lucena-Araujo AR, Coelho-Silva JL, Pereira-Martins DA, Thomé C, Scheucher PS, Lange AP, Paiva HH, Hemmelgarn BT, Morais-Sobral MC, Azevedo EA, Franca-Neto PL, Franca RF, Silva CL, Krause A, Rego EM.

Oncotarget. 2017 Jan 31;8(5):8475-8483. doi: 10.18632/oncotarget.14295.

15.

The experience of the International Consortium on Acute Promyelocytic Leukemia in monitoring minimal residual disease in acute promyelocytic leukaemia.

Lange AP, Lima AS, Lucena-Araujo AR, Jácomo RH, Melo RA, Bittencourt RI, Pasquini R, Pagnano K, Fagundes EM, Chauffaille ML, Chiattone CS, Sanz MA, Lo-Coco F, Grimwade D, Rego EM.

Br J Haematol. 2018 Mar;180(6):915-918. doi: 10.1111/bjh.14490. Epub 2016 Dec 26. No abstract available.

PMID:
28025822
16.

Association between the TP53 Arg72Pro polymorphism and clinical outcomes in acute myeloid leukemia.

Bezerra MF, Coelho-Silva JL, Nascimento JC, Benicio MT, Rocha CR, Machado CG, Rego EM, Bezerra MA, Lucena-Araujo AR, Beltrão EI.

Haematologica. 2017 Feb;102(2):e43-e46. doi: 10.3324/haematol.2016.155069. Epub 2016 Oct 20. No abstract available.

17.

De novo ALK kinase domain mutations are uncommon in kinase inhibitor-naïve ALK rearranged lung cancers.

Lucena-Araujo AR, Moran JP, VanderLaan PA, Dias-Santagata D, Folch E, Majid A, Kent MS, Gangadharan SP, Rangachari D, Huberman MS, Kobayashi SS, Costa DB.

Lung Cancer. 2016 Sep;99:17-22. doi: 10.1016/j.lungcan.2016.06.006. Epub 2016 Jun 14.

18.

Prognostic importance of CD56 expression in intermediate risk acute myeloid leukaemia.

Coelho-Silva JL, Carvalho LE, Oliveira MM, Franca-Neto PL, Andrade AT, Lima AS, Bezerra MF, Lima MM, Neves MA, Fonseca JM, Barros-Correia MC, Machado CG, Bezerra MA, Matos DM, Lucena-Araujo AR.

Br J Haematol. 2017 Feb;176(3):498-501. doi: 10.1111/bjh.13971. Epub 2016 Feb 23. No abstract available.

PMID:
26914377
19.

Residual expression of SMYD2 and SMYD3 is associated with the acquisition of complex karyotype in chronic lymphocytic leukemia.

Oliveira-Santos W, Rabello DA, Lucena-Araujo AR, de Oliveira FM, Rego EM, Pittella Silva F, Saldanha-Araujo F.

Tumour Biol. 2016 Jul;37(7):9473-81. doi: 10.1007/s13277-016-4846-z. Epub 2016 Jan 20.

PMID:
26790435
20.

High ΔNp73/TAp73 ratio is associated with poor prognosis in acute promyelocytic leukemia.

Lucena-Araujo AR, Kim HT, Thomé C, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Glória AB, Chauffaille Mde L, Athayde M, Chiattone CS, Mito I, Bendlin R, Souza C, Bortolheiro C, Coelho-Silva JL, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM.

Blood. 2015 Nov 12;126(20):2302-6. doi: 10.1182/blood-2015-01-623330. Epub 2015 Oct 1.

21.

Clinical outcomes of patients with acute myeloid leukemia: evaluation of genetic and molecular findings in a real-life setting.

Lima AS, de Mello MR, Fernandes E, Bezerra MF, Oliveira MM, Duarte BK, de Assis RA, Souto FR, Ramos CF, Machado CG, Pagnano K, Lucena-Araujo AR, Lorand-Metze I, Bezerra MA.

Blood. 2015 Oct 8;126(15):1863-5. doi: 10.1182/blood-2015-07-657551. Epub 2015 Aug 28. No abstract available.

PMID:
26320101
22.

Potential roles of microRNA-29a in the molecular pathophysiology of T-cell acute lymphoblastic leukemia.

Oliveira LH, Schiavinato JL, Fráguas MS, Lucena-Araujo AR, Haddad R, Araújo AG, Dalmazzo LF, Rego EM, Covas DT, Zago MA, Panepucci RA.

Cancer Sci. 2015 Oct;106(10):1264-77. doi: 10.1111/cas.12766. Epub 2015 Sep 21.

23.

Lack of association between the Duffy antigen receptor for chemokines (DARC) expression and clinical outcome of children with sickle cell anemia.

Araujo NB, Domingos IF, Medeiros FS, Hatzlhofer BL, Mendonça TF, Vasconcelos LR, Cavalcanti Mdo S, Araujo AS, Oliveira Mdo C, Lucena-Araujo AR, Bezerra MA.

Immunol Lett. 2015 Aug;166(2):140-2. doi: 10.1016/j.imlet.2015.05.015. Epub 2015 Jun 1. No abstract available.

PMID:
26045319
24.

Detection of Crizotinib-Sensitive Lung Adenocarcinomas With MET, ALK, and ROS1 Genomic Alterations via Comprehensive Genomic Profiling.

Le X, Freed JA, VanderLaan PA, Huberman MS, Rangachari D, Jorge SE, Lucena-Araujo AR, Kobayashi SS, Balasubramanian S, He J, Chudnovsky Y, Miller VA, Ali SM, Costa DB.

Clin Lung Cancer. 2015 Sep;16(5):e105-9. doi: 10.1016/j.cllc.2015.03.002. Epub 2015 Mar 25. No abstract available.

25.

Prevalence and molecular defect characterization of glucose-6-phosphate dehydrogenase deficiency in Brazilian blood donors.

Domingos IF, Hatzlhofer BL, Oliveira FB, Araujo FR, Araujo AS, Lucena-Araujo AR, Bezerra MA.

Int J Lab Hematol. 2015 Oct;37(5):e109-11. doi: 10.1111/ijlh.12341. Epub 2015 Mar 9. No abstract available.

PMID:
25752191
26.

Overexpression of EZH2 associates with a poor prognosis in chronic lymphocytic leukemia.

Rabello Ddo A, Lucena-Araujo AR, Alves-Silva JC, da Eira VB, de Vasconcellos MC, de Oliveira FM, Rego EM, Saldanha-Araujo F, Pittella Silva F.

Blood Cells Mol Dis. 2015 Jan;54(1):97-102. doi: 10.1016/j.bcmd.2014.07.013. Epub 2014 Aug 15.

PMID:
25131810
27.

Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study.

Lucena-Araujo AR, Kim HT, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Fagundes EM, Chauffaille Mde L, Chiattone CS, Lima AS, Ruiz-Argüelles G, Undurraga MS, Martinez L, Kwaan HC, Gallagher R, Niemeyer CM, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM.

Ann Hematol. 2014 Dec;93(12):2001-10. doi: 10.1007/s00277-014-2142-9. Epub 2014 Jul 2.

PMID:
24981688
28.

Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukaemia study.

Lucena-Araujo AR, Kim HT, Jacomo RH, Melo RA, Bittencourt R, Pasquini R, Pagnano K, Fagundes EM, de Lourdes Chauffaille M, Chiattone CS, Lima AS, Kwaan HC, Gallagher R, Niemeyer CM, Schrier SL, Tallman MS, Grimwade D, Ganser A, Berliner N, Ribeiro RC, Lo-Coco F, Löwenberg B, Sanz MA, Rego EM.

Br J Haematol. 2014 Aug;166(4):540-9. doi: 10.1111/bjh.12921. Epub 2014 May 3.

PMID:
24796963
29.

Mantle cell lymphoma harboring Burkitt's-like translocations presents differential expression of aurora kinase genes compared with others 8q abnormalities.

de Oliveira FM, Rodrigues-Alves AP, Lucena-Araújo AR, de Paula Silva F, da Silva FB, Falcão RP.

Med Oncol. 2014 May;31(5):931. doi: 10.1007/s12032-014-0931-6. Epub 2014 Mar 29.

PMID:
24683001
30.

Mannose-binding lectin 2 (MBL2) gene polymorphisms do not influence frequency of infections in chronic lymphocytic leukemia patients.

Holanda K, Lucena-Araujo AR, Quintas A, Mendonça T, Lima A, Vasconcelos LR, Moura P, Cavalcanti M, Machado C, Araújo AS, Bezerra MA.

Rev Bras Hematol Hemoter. 2014;36(1):29-34. doi: 10.5581/1516-8484.20140010.

31.

Influence of the βs haplotype and α-thalassemia on stroke development in a Brazilian population with sickle cell anaemia.

Domingos IF, Falcão DA, Hatzlhofer BL, Cunha AF, Santos MN, Albuquerque DM, Fertrin KY, Costa FF, Azevedo RC, Machado CG, Araújo AS, Lucena-Araujo AR, Bezerra MA.

Ann Hematol. 2014 Jul;93(7):1123-9. doi: 10.1007/s00277-014-2016-1. Epub 2014 Feb 4.

PMID:
24493127
32.

Structural, biochemical, and clinical characterization of epidermal growth factor receptor (EGFR) exon 20 insertion mutations in lung cancer.

Yasuda H, Park E, Yun CH, Sng NJ, Lucena-Araujo AR, Yeo WL, Huberman MS, Cohen DW, Nakayama S, Ishioka K, Yamaguchi N, Hanna M, Oxnard GR, Lathan CS, Moran T, Sequist LV, Chaft JE, Riely GJ, Arcila ME, Soo RA, Meyerson M, Eck MJ, Kobayashi SS, Costa DB.

Sci Transl Med. 2013 Dec 18;5(216):216ra177. doi: 10.1126/scitranslmed.3007205. Erratum in: Sci Transl Med. 2014 Feb 26;6(225):225er1.

33.

Dual ALK and EGFR inhibition targets a mechanism of acquired resistance to the tyrosine kinase inhibitor crizotinib in ALK rearranged lung cancer.

Yamaguchi N, Lucena-Araujo AR, Nakayama S, de Figueiredo-Pontes LL, Gonzalez DA, Yasuda H, Kobayashi S, Costa DB.

Lung Cancer. 2014 Jan;83(1):37-43. doi: 10.1016/j.lungcan.2013.09.019. Epub 2013 Oct 14.

34.

Increased expression of miR-221 is associated with shorter overall survival in T-cell acute lymphoid leukemia.

Gimenes-Teixeira HL, Lucena-Araujo AR, Dos Santos GA, Zanette DL, Scheucher PS, Oliveira LC, Dalmazzo LF, Silva-Júnior WA, Falcão RP, Rego EM.

Exp Hematol Oncol. 2013 Apr 8;2(1):10. doi: 10.1186/2162-3619-2-10.

35.

FISH analysis for TET2 deletion in a cohort of 362 Brazilian myeloid malignancies: correlation with karyotype abnormalities.

de Oliveira FM, Miguel CE, Lucena-Araujo AR, de Lima AS, Falcão RP, Rego EM.

Med Oncol. 2013 Mar;30(1):483. doi: 10.1007/s12032-013-0483-1. Epub 2013 Feb 7.

PMID:
23389918
36.

Differential expression of AURKA and AURKB genes in bone marrow stromal mesenchymal cells of myelodysplastic syndrome: correlation with G-banding analysis and FISH.

Oliveira FM, Lucena-Araujo AR, Favarin Mdo C, Palma PV, Rego EM, Falcão RP, Covas DT, Fontes AM.

Exp Hematol. 2013 Feb;41(2):198-208. doi: 10.1016/j.exphem.2012.10.009. Epub 2012 Oct 22.

PMID:
23092930
37.

Comparative analysis of the pathological events involved in immune and non-immune TRALI models.

Tamarozzi MB, Soares SG, Sá-Nunes A, Paiva HH, Saggioro FP, Garcia AB, Lucena-Araujo AR, Falcão RP, Bordin JO, Rego EM.

Vox Sang. 2012 Nov;103(4):309-21. doi: 10.1111/j.1423-0410.2012.01613.x. Epub 2012 May 25.

PMID:
22624696
38.

(+)α-Tocopheryl succinate inhibits the mitochondrial respiratory chain complex I and is as effective as arsenic trioxide or ATRA against acute promyelocytic leukemia in vivo.

dos Santos GA, Abreu e Lima RS, Pestana CR, Lima AS, Scheucher PS, Thomé CH, Gimenes-Teixeira HL, Santana-Lemos BA, Lucena-Araujo AR, Rodrigues FP, Nasr R, Uyemura SA, Falcão RP, de Thé H, Pandolfi PP, Curti C, Rego EM.

Leukemia. 2012 Mar;26(3):451-60. doi: 10.1038/leu.2011.216. Epub 2011 Aug 26.

PMID:
21869839
39.

Identification of a new translocation that disrupts the RUNX1 gene in a patient with de novo acute myeloid leukemia.

Lucena-Araujo AR, de Figueiredo-Pontes LL, de Oliveira FM, de Lourdes Chauffaille M, Falcao RP, Rego EM.

Med Oncol. 2012 Jun;29(2):1114-8. doi: 10.1007/s12032-011-9890-3. Epub 2011 Mar 6.

PMID:
21380778
40.

The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated.

Santana-Lemos BA, de Lima Lange AP, de Lira Benício MT, José TD, Lucena-Araújo AR, Krause A, Thomé CH, Rego EM.

Haematologica. 2011 Apr;96(4):617-20. doi: 10.3324/haematol.2010.028365. Epub 2010 Dec 6.

41.

High expression of AURKA and AURKB is associated with unfavorable cytogenetic abnormalities and high white blood cell count in patients with acute myeloid leukemia.

Lucena-Araujo AR, de Oliveira FM, Leite-Cueva SD, dos Santos GA, Falcao RP, Rego EM.

Leuk Res. 2011 Feb;35(2):260-4. doi: 10.1016/j.leukres.2010.07.034. Epub 2010 Aug 21.

PMID:
20732714
42.

Segmental amplification of MLL gene associated with high expression of AURKA and AURKB genes in a case of acute monoblastic leukemia with complex karyotype.

Oliveira FM, Lucena-Araújo AR, Leite-Cueva SD, Santos GA, Rego EM, Falcão RP.

Cancer Genet Cytogenet. 2010 Apr 1;198(1):62-5. doi: 10.1016/j.cancergencyto.2009.12.005.

PMID:
20303016
43.

Results of FLT3 mutation screening and correlations with immunophenotyping in 169 Brazilian patients with acute myeloid leukemia.

Lucena-Araujo AR, Souza DL, Morato de Oliveira F, Benicio MT, Figueiredo-Pontes LL, Santana-Lemos BA, dos Santos GA, Jacomo RH, Dinarte-Santos AR, Yamamoto M, Silva WA Jr, de Lourdes Chauffaille M, Rego EM.

Ann Hematol. 2010 Feb;89(2):225-8. doi: 10.1007/s00277-009-0860-1. No abstract available. Erratum in: Ann Hematol. 2010 Feb;89(2):229-30.

PMID:
19921191
44.

Apoptosis induction by (+)alpha-tocopheryl succinate in the absence or presence of all-trans retinoic acid and arsenic trioxide in NB4, NB4-R2 and primary APL cells.

Freitas RA, Silva dos Santos GA, Gimenes Teixeira HL, Scheucher PS, Lucena-Araujo AR, Lima AS, Abreu e Lima RS, Garcia AB, Jordão AA Jr, Falcão RP, Vannucchi H, Rego EM.

Leuk Res. 2009 Jul;33(7):958-63. doi: 10.1016/j.leukres.2008.09.035. Epub 2008 Nov 14.

PMID:
19013639
45.

The expression of DeltaNTP73, TATP73 and TP53 genes in acute myeloid leukaemia is associated with recurrent cytogenetic abnormalities and in vitro susceptibility to cytarabine cytotoxicity.

Lucena-Araujo AR, Panepucci RA, dos Santos GA, Jácomo RH, Santana-Lemos BA, Lima AS, Garcia AB, Araújo AG, Falcão RP, Rego EM.

Br J Haematol. 2008 Jul;142(1):74-8. doi: 10.1111/j.1365-2141.2008.07160.x. Epub 2008 Apr 17.

PMID:
18422993

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