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Items: 1 to 50 of 159

1.

Phosphodiesterase 10A IgG: A novel biomarker of paraneoplastic neurologic autoimmunity.

Zekeridou A, Kryzer T, Guo Y, Hassan A, Lennon V, Lucchinetti CF, Pittock S, McKeon A.

Neurology. 2019 Aug 20;93(8):e815-e822. doi: 10.1212/WNL.0000000000007971. Epub 2019 Jul 17.

PMID:
31315972
2.

Using germline variants to estimate glioma and subtype risks.

Eckel-Passow JE, Decker PA, Kosel ML, Kollmeyer TM, Molinaro AM, Rice T, Caron AA, Drucker KL, Praska CE, Pekmezci M, Hansen HM, McCoy LS, Bracci PM, Erickson BJ, Lucchinetti CF, Wiemels JL, Wiencke JK, Bondy ML, Melin B, Burns TC, Giannini C, Lachance DH, Wrensch MR, Jenkins RB.

Neuro Oncol. 2019 Mar 18;21(4):451-461. doi: 10.1093/neuonc/noz009.

PMID:
30624711
3.

Clinical, Radiologic, and Prognostic Features of Myelitis Associated With Myelin Oligodendrocyte Glycoprotein Autoantibody.

Dubey D, Pittock SJ, Krecke KN, Morris PP, Sechi E, Zalewski NL, Weinshenker BG, Shosha E, Lucchinetti CF, Fryer JP, Lopez-Chiriboga AS, Chen JC, Jitprapaikulsan J, McKeon A, Gadoth A, Keegan BM, Tillema JM, Naddaf E, Patterson MC, Messacar K, Tyler KL, Flanagan EP.

JAMA Neurol. 2019 Mar 1;76(3):301-309. doi: 10.1001/jamaneurol.2018.4053.

PMID:
30575890
4.

Paraneoplastic neuronal intermediate filament autoimmunity.

Basal E, Zalewski N, Kryzer TJ, Hinson SR, Guo Y, Dubey D, Benarroch EE, Lucchinetti CF, Pittock SJ, Lennon VA, McKeon A.

Neurology. 2018 Oct 30;91(18):e1677-e1689. doi: 10.1212/WNL.0000000000006435. Epub 2018 Oct 3.

5.

Population-based study of "no evident disease activity" in MS.

Parks NE, Pittock SJ, Mandrekar J, Kantarci OH, Lucchinetti CF, Weinshenker BG, Keegan BM, Tobin WO, Tillema JM, Toledano M, Flanagan EP.

Neurol Neuroimmunol Neuroinflamm. 2018 Aug 16;5(6):e495. doi: 10.1212/NXI.0000000000000495. eCollection 2018 Nov.

6.

Myelin Oligodendrocyte Glycoprotein Antibody-Positive Optic Neuritis: Clinical Characteristics, Radiologic Clues, and Outcome.

Chen JJ, Flanagan EP, Jitprapaikulsan J, López-Chiriboga ASS, Fryer JP, Leavitt JA, Weinshenker BG, McKeon A, Tillema JM, Lennon VA, Tobin WO, Keegan BM, Lucchinetti CF, Kantarci OH, McClelland CM, Lee MS, Bennett JL, Pelak VS, Chen Y, VanStavern G, Adesina OO, Eggenberger ER, Acierno MD, Wingerchuk DM, Brazis PW, Sagen J, Pittock SJ.

Am J Ophthalmol. 2018 Nov;195:8-15. doi: 10.1016/j.ajo.2018.07.020. Epub 2018 Jul 26.

7.

Neuromyelitis Optica and Herpes Simplex Virus 2: A Viral Trigger for Aquaporin-4 Autoimmunity?

Marin Collazo IV, Howe CL, Lucchinetti CF, Tobin WO.

Neurologist. 2018 May;23(3):92-93. doi: 10.1097/NRL.0000000000000172.

PMID:
29722742
8.

Dark Rims: Novel Sequence Enhances Diagnostic Specificity in Multiple Sclerosis.

Tillema JM, Weigand SD, Dayan M, Shu Y, Kantarci OH, Lucchinetti CF, Port JD.

AJNR Am J Neuroradiol. 2018 Jun;39(6):1052-1058. doi: 10.3174/ajnr.A5636. Epub 2018 Apr 26.

9.

Differences in the Reponses to Apheresis Therapy of Patients With 3 Histopathologically Classified Immunopathological Patterns of Multiple Sclerosis.

Stork L, Ellenberger D, Beißbarth T, Friede T, Lucchinetti CF, Brück W, Metz I.

JAMA Neurol. 2018 Apr 1;75(4):428-435. doi: 10.1001/jamaneurol.2017.4842.

10.

Multiple Sclerosis.

Reich DS, Lucchinetti CF, Calabresi PA.

N Engl J Med. 2018 Jan 11;378(2):169-180. doi: 10.1056/NEJMra1401483. Review. No abstract available.

PMID:
29320652
11.

NEDA treatment target? No evident disease activity as an actionable outcome in practice.

Parks NE, Flanagan EP, Lucchinetti CF, Wingerchuk DM.

J Neurol Sci. 2017 Dec 15;383:31-34. doi: 10.1016/j.jns.2017.10.015. Epub 2017 Oct 13. Review.

PMID:
29246616
12.

Purkinje cell cytoplasmic antibody type I (anti-Yo): predictive of gastrointestinal adenocarcinomas in men.

Linnoila J, Guo Y, Gadoth A, Raghunathan A, Parks B, McKeon A, Lucchinetti CF, Lennon VA, Pittock SJ.

J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1116-1117. doi: 10.1136/jnnp-2017-316829. Epub 2017 Nov 15. No abstract available.

PMID:
29142142
13.

Diagnostic criteria for chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS).

Tobin WO, Guo Y, Krecke KN, Parisi JE, Lucchinetti CF, Pittock SJ, Mandrekar J, Dubey D, Debruyne J, Keegan BM.

Brain. 2017 Sep 1;140(9):2415-2425. doi: 10.1093/brain/awx200.

PMID:
29050399
14.

Clinical Reasoning: A 50-year-old woman with SLE and a tumefactive lesion.

Choi JH, Wallach AI, Rosales D, Margiewicz SE, Belmont HM, Lucchinetti CF, Minen MT.

Neurology. 2017 Sep 19;89(12):e140-e145. doi: 10.1212/WNL.0000000000004386. No abstract available.

PMID:
28923891
15.

Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions.

Popescu BF, Frischer JM, Webb SM, Tham M, Adiele RC, Robinson CA, Fitz-Gibbon PD, Weigand SD, Metz I, Nehzati S, George GN, Pickering IJ, Brück W, Hametner S, Lassmann H, Parisi JE, Yong G, Lucchinetti CF.

Acta Neuropathol. 2017 Jul;134(1):45-64. doi: 10.1007/s00401-017-1696-8. Epub 2017 Mar 22.

16.

Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica.

Guo Y, Weigand SD, Popescu BF, Lennon VA, Parisi JE, Pittock SJ, Parks NE, Clardy SL, Howe CL, Lucchinetti CF.

Acta Neuropathol. 2017 Apr;133(4):597-612. doi: 10.1007/s00401-017-1682-1. Epub 2017 Feb 9.

17.

Ring-enhancing spinal cord lesions in neuromyelitis optica spectrum disorders.

Zalewski NL, Morris PP, Weinshenker BG, Lucchinetti CF, Guo Y, Pittock SJ, Krecke KN, Kaufmann TJ, Wingerchuk DM, Kumar N, Flanagan EP.

J Neurol Neurosurg Psychiatry. 2017 Mar;88(3):218-225. doi: 10.1136/jnnp-2016-314738. Epub 2016 Dec 2.

PMID:
27913626
18.

Clinical-radiological-pathological spectrum of central nervous system-idiopathic inflammatory demyelinating disease in the elderly.

Tobin WO, Costanzi C, Guo Y, Parisi JE, Weigand SD, Lucchinetti CF.

Mult Scler. 2017 Aug;23(9):1204-1213. doi: 10.1177/1352458516675748. Epub 2016 Oct 19.

19.

In vivo detection of connectivity between cortical and white matter lesions in early MS.

Tillema JM, Weigand SD, Mandrekar J, Shu Y, Lucchinetti CF, Pirko I, Port JD.

Mult Scler. 2017 Jun;23(7):973-981. doi: 10.1177/1352458516671027. Epub 2016 Oct 3.

20.

Neuropilin-1 modulates interferon-γ-stimulated signaling in brain microvascular endothelial cells.

Wang Y, Cao Y, Mangalam AK, Guo Y, LaFrance-Corey RG, Gamez JD, Atanga PA, Clarkson BD, Zhang Y, Wang E, Angom RS, Dutta K, Ji B, Pirko I, Lucchinetti CF, Howe CL, Mukhopadhyay D.

J Cell Sci. 2016 Oct 15;129(20):3911-3921. Epub 2016 Sep 2.

21.

Acute disseminated encephalomyelitis: Updates on an inflammatory CNS syndrome.

Pohl D, Alper G, Van Haren K, Kornberg AJ, Lucchinetti CF, Tenembaum S, Belman AL.

Neurology. 2016 Aug 30;87(9 Suppl 2):S38-45. doi: 10.1212/WNL.0000000000002825. Review.

PMID:
27572859
22.

Atypical inflammatory demyelinating syndromes of the CNS.

Hardy TA, Reddel SW, Barnett MH, Palace J, Lucchinetti CF, Weinshenker BG.

Lancet Neurol. 2016 Aug;15(9):967-981. doi: 10.1016/S1474-4422(16)30043-6. Review.

PMID:
27478954
23.

LRP1 expression in microglia is protective during CNS autoimmunity.

Chuang TY, Guo Y, Seki SM, Rosen AM, Johanson DM, Mandell JW, Lucchinetti CF, Gaultier A.

Acta Neuropathol Commun. 2016 Jul 11;4(1):68. doi: 10.1186/s40478-016-0343-2.

24.

Meningeal mast cell-T cell crosstalk regulates T cell encephalitogenicity.

Russi AE, Walker-Caulfield ME, Guo Y, Lucchinetti CF, Brown MA.

J Autoimmun. 2016 Sep;73:100-10. doi: 10.1016/j.jaut.2016.06.015. Epub 2016 Jul 5.

25.

Immunopathology: autoimmune glial diseases and differentiation from multiple sclerosis.

Popescu BF, Lucchinetti CF.

Handb Clin Neurol. 2016;133:95-106. doi: 10.1016/B978-0-444-63432-0.00006-2. Review.

PMID:
27112673
26.

Relapses in multiple sclerosis: Relationship to disability.

Goodin DS, Reder AT, Bermel RA, Cutter GR, Fox RJ, John GR, Lublin FD, Lucchinetti CF, Miller AE, Pelletier D, Racke MK, Trapp BD, Vartanian T, Waubant E.

Mult Scler Relat Disord. 2016 Mar;6:10-20. doi: 10.1016/j.msard.2015.09.002. Epub 2015 Sep 8. Review.

PMID:
27063617
27.

Exploring the overlap between multiple sclerosis, tumefactive demyelination and Baló's concentric sclerosis.

Hardy TA, Tobin WO, Lucchinetti CF.

Mult Scler. 2016 Jul;22(8):986-92. doi: 10.1177/1352458516641776. Epub 2016 Apr 1. Review.

PMID:
27037180
28.

Epidemiology of aquaporin-4 autoimmunity and neuromyelitis optica spectrum.

Flanagan EP, Cabre P, Weinshenker BG, Sauver JS, Jacobson DJ, Majed M, Lennon VA, Lucchinetti CF, McKeon A, Matiello M, Kale N, Wingerchuk DM, Mandrekar J, Sagen JA, Fryer JP, Robinson AB, Pittock SJ.

Ann Neurol. 2016 May;79(5):775-783. doi: 10.1002/ana.24617. Epub 2016 Apr 4.

29.

Multiple sclerosis masquerading as Alzheimer-type dementia: Clinical, radiological and pathological findings.

Tobin WO, Popescu BF, Lowe V, Pirko I, Parisi JE, Kantarci K, Fields JA, Bruns MB, Boeve BF, Lucchinetti CF.

Mult Scler. 2016 Apr;22(5):698-704. doi: 10.1177/1352458515604382. Epub 2015 Oct 7.

30.

NFκB signaling drives pro-granulocytic astroglial responses to neuromyelitis optica patient IgG.

Walker-Caulfield ME, Guo Y, Johnson RK, McCarthy CB, Fitz-Gibbon PD, Lucchinetti CF, Howe CL.

J Neuroinflammation. 2015 Sep 30;12:185. doi: 10.1186/s12974-015-0403-8.

31.

Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque.

Frischer JM, Weigand SD, Guo Y, Kale N, Parisi JE, Pirko I, Mandrekar J, Bramow S, Metz I, Brück W, Lassmann H, Lucchinetti CF.

Ann Neurol. 2015 Nov;78(5):710-21. doi: 10.1002/ana.24497. Epub 2015 Aug 24.

32.

Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis.

Novotna M, Paz Soldán MM, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Aug 25;85(8):722-9. doi: 10.1212/WNL.0000000000001856. Epub 2015 Jul 24. Erratum in: Neurology. 2015 Oct 13;85(15):1355.

33.

Neuromyelitis optica and the evolving spectrum of autoimmune aquaporin-4 channelopathies: a decade later.

Pittock SJ, Lucchinetti CF.

Ann N Y Acad Sci. 2016 Feb;1366(1):20-39. doi: 10.1111/nyas.12794. Epub 2015 Jun 10. Review.

34.

Corrigendum: multiple sclerosis-a quiet revolution.

Ransohoff RM, Hafler DA, Lucchinetti CF.

Nat Rev Neurol. 2015 May;11(5):246. doi: 10.1038/nrneurol.2015.49. Epub 2015 Mar 24. No abstract available.

PMID:
25799926
35.

Multiple sclerosis-a quiet revolution.

Ransohoff RM, Hafler DA, Lucchinetti CF.

Nat Rev Neurol. 2015 Mar;11(3):134-42. doi: 10.1038/nrneurol.2015.14. Epub 2015 Feb 17. Review. Erratum in: Nat Rev Neurol. 2015 May;11(5):246.

36.

Extensive acute axonal damage in pediatric multiple sclerosis lesions.

Pfeifenbring S, Bunyan RF, Metz I, Röver C, Huppke P, Gärtner J, Lucchinetti CF, Brück W.

Ann Neurol. 2015 Apr;77(4):655-67. doi: 10.1002/ana.24364. Epub 2015 Feb 26.

37.

Diagnostic utility of aquaporin-4 in the analysis of active demyelinating lesions.

Popescu BF, Guo Y, Jentoft ME, Parisi JE, Lennon VA, Pittock SJ, Weinshenker BG, Wingerchuk DM, Giannini C, Metz I, Brück W, Shuster EA, Carter J, Boyd CD, Clardy SL, Cohen BA, Lucchinetti CF.

Neurology. 2015 Jan 13;84(2):148-58. doi: 10.1212/WNL.0000000000001126. Epub 2014 Dec 10.

38.

Relapses and disability accumulation in progressive multiple sclerosis.

Paz Soldán MM, Novotna M, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Weinshenker BG, Rodriguez M, Kantarci OH.

Neurology. 2015 Jan 6;84(1):81-8. doi: 10.1212/WNL.0000000000001094. Epub 2014 Nov 14.

39.

Short myelitis lesions in aquaporin-4-IgG-positive neuromyelitis optica spectrum disorders.

Flanagan EP, Weinshenker BG, Krecke KN, Lennon VA, Lucchinetti CF, McKeon A, Wingerchuk DM, Shuster EA, Jiao Y, Horta ES, Pittock SJ.

JAMA Neurol. 2015 Jan;72(1):81-7. doi: 10.1001/jamaneurol.2014.2137.

40.

AQP4 autoantibody assay performance in clinical laboratory service.

Fryer JP, Lennon VA, Pittock SJ, Jenkins SM, Fallier-Becker P, Clardy SL, Horta E, Jedynak EA, Lucchinetti CF, Shuster EA, Weinshenker BG, Wingerchuk DM, McKeon A.

Neurol Neuroimmunol Neuroinflamm. 2014 May 22;1(1):e11. doi: 10.1212/NXI.0000000000000011. eCollection 2014 Jun.

41.

DPPX potassium channel antibody: frequency, clinical accompaniments, and outcomes in 20 patients.

Tobin WO, Lennon VA, Komorowski L, Probst C, Clardy SL, Aksamit AJ, Appendino JP, Lucchinetti CF, Matsumoto JY, Pittock SJ, Sandroni P, Tippmann-Peikert M, Wirrell EC, McKeon A.

Neurology. 2014 Nov 11;83(20):1797-803. doi: 10.1212/WNL.0000000000000991. Epub 2014 Oct 15.

42.

Investigation of the KIR4.1 potassium channel as a putative antigen in patients with multiple sclerosis: a comparative study.

Brickshawana A, Hinson SR, Romero MF, Lucchinetti CF, Guo Y, Buttmann M, McKeon A, Pittock SJ, Chang MH, Chen AP, Kryzer TJ, Fryer JP, Jenkins SM, Cabre P, Lennon VA.

Lancet Neurol. 2014 Aug;13(8):795-806. doi: 10.1016/S1474-4422(14)70141-3. Epub 2014 Jul 6.

43.

Autoimmune aquaporin-4 myopathy in neuromyelitis optica spectrum.

Guo Y, Lennon VA, Popescu BF, Grouse CK, Topel J, Milone M, Lassmann H, Parisi JE, Pittock SJ, Stefoski D, Balabanov R, Lucchinetti CF.

JAMA Neurol. 2014 Aug;71(8):1025-9. doi: 10.1001/jamaneurol.2014.775.

PMID:
24911400
44.

Early and widespread injury of astrocytes in the absence of demyelination in acute haemorrhagic leukoencephalitis.

Robinson CA, Adiele RC, Tham M, Lucchinetti CF, Popescu BF.

Acta Neuropathol Commun. 2014 May 8;2:52. doi: 10.1186/2051-5960-2-52.

45.

Longitudinally extensive transverse myelitis.

Tobin WO, Weinshenker BG, Lucchinetti CF.

Curr Opin Neurol. 2014 Jun;27(3):279-89. doi: 10.1097/WCO.0000000000000093. Review.

PMID:
24792338
46.

Pathologic heterogeneity persists in early active multiple sclerosis lesions.

Metz I, Weigand SD, Popescu BF, Frischer JM, Parisi JE, Guo Y, Lassmann H, Brück W, Lucchinetti CF.

Ann Neurol. 2014 May;75(5):728-38. doi: 10.1002/ana.24163. Epub 2014 May 13.

47.

Hydrocephalus in neuromyelitis optica.

Clardy SL, Lucchinetti CF, Krecke KN, Lennon VA, O'Toole O, Weinshenker BG, Boyd CD, Krieger S, McGraw C, Guo Y, Pittock SJ.

Neurology. 2014 May 20;82(20):1841-3. doi: 10.1212/WNL.0000000000000428. Epub 2014 Apr 23. No abstract available.

48.

Paraneoplastic neuromyelitis optica spectrum disorder associated with metastatic carcinoid expressing aquaporin-4.

Figueroa M, Guo Y, Tselis A, Pittock SJ, Lennon VA, Lucchinetti CF, Lisak RP.

JAMA Neurol. 2014 Apr;71(4):495-8. doi: 10.1001/jamaneurol.2013.6331.

49.

Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures.

Howe CL, Kaptzan T, Magaña SM, Ayers-Ringler JR, LaFrance-Corey RG, Lucchinetti CF.

Glia. 2014 May;62(5):692-708. doi: 10.1002/glia.22635. Epub 2014 Feb 3.

50.

The pathology of an autoimmune astrocytopathy: lessons learned from neuromyelitis optica.

Lucchinetti CF, Guo Y, Popescu BF, Fujihara K, Itoyama Y, Misu T.

Brain Pathol. 2014 Jan;24(1):83-97. doi: 10.1111/bpa.12099. Review.

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