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Items: 1 to 50 of 55

1.

Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial.

Lawlor B, Segurado R, Kennelly S, Olde Rikkert MGM, Howard R, Pasquier F, Börjesson-Hanson A, Tsolaki M, Lucca U, Molloy DW, Coen R, Riepe MW, Kálmán J, Kenny RA, Cregg F, O'Dwyer S, Walsh C, Adams J, Banzi R, Breuilh L, Daly L, Hendrix S, Aisen P, Gaynor S, Sheikhi A, Taekema DG, Verhey FR, Nemni R, Nobili F, Franceschi M, Frisoni G, Zanetti O, Konsta A, Anastasios O, Nenopoulou S, Tsolaki-Tagaraki F, Pakaski M, Dereeper O, de la Sayette V, Sénéchal O, Lavenu I, Devendeville A, Calais G, Crawford F, Mullan M; NILVAD Study Group.

PLoS Med. 2018 Sep 24;15(9):e1002660. doi: 10.1371/journal.pmed.1002660. eCollection 2018 Sep.

2.

Relationship between atrial fibrillation and cognitive decline in individuals aged 80 and older.

Proietti M, Recchia A, Riva E, Lucca U, Tettamanti M, Mannucci PM, Nobili A.

Eur J Intern Med. 2017 Dec;46:6-10. doi: 10.1016/j.ejim.2017.08.010. Epub 2017 Aug 9. Review.

PMID:
28803036
3.

Prognostic value of degree and types of anaemia on clinical outcomes for hospitalised older patients.

Riva E, Colombo R, Moreo G, Mandelli S, Franchi C, Pasina L, Tettamanti M, Lucca U, Mannucci PM, Nobili A; REPOSI Investigators.

Arch Gerontol Geriatr. 2017 Mar - Apr;69:21-30. doi: 10.1016/j.archger.2016.11.005. Epub 2016 Nov 14.

PMID:
27875713
4.

Nutrition for the ageing brain: Towards evidence for an optimal diet.

Vauzour D, Camprubi-Robles M, Miquel-Kergoat S, Andres-Lacueva C, Bánáti D, Barberger-Gateau P, Bowman GL, Caberlotto L, Clarke R, Hogervorst E, Kiliaan AJ, Lucca U, Manach C, Minihane AM, Mitchell ES, Perneczky R, Perry H, Roussel AM, Schuermans J, Sijben J, Spencer JP, Thuret S, van de Rest O, Vandewoude M, Wesnes K, Williams RJ, Williams RS, Ramirez M.

Ageing Res Rev. 2017 May;35:222-240. doi: 10.1016/j.arr.2016.09.010. Epub 2016 Oct 3. Review.

5.

Older patients are still under-represented in clinical trials of Alzheimer's disease.

Banzi R, Camaioni P, Tettamanti M, Bertele' V, Lucca U.

Alzheimers Res Ther. 2016 Aug 12;8:32. doi: 10.1186/s13195-016-0201-2. Review.

6.

European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease-the substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow.

Meulenbroek O, O'Dwyer S, de Jong D, van Spijker G, Kennelly S, Cregg F, Olde Rikkert M, Abdullah L, Wallin A, Walsh C, Coen R, Kenny RA, Daly L, Segurado R, Borjesson-Hanson A, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Molloy W, Tsolaki M, Howard R, Adams J, Gaynor S, Lawlor B.

BMJ Open. 2016 Jul 19;6(7):e011584. doi: 10.1136/bmjopen-2016-011584.

7.

ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups.

Brodaty H, Woolf C, Andersen S, Barzilai N, Brayne C, Cheung KS, Corrada MM, Crawford JD, Daly C, Gondo Y, Hagberg B, Hirose N, Holstege H, Kawas C, Kaye J, Kochan NA, Lau BH, Lucca U, Marcon G, Martin P, Poon LW, Richmond R, Robine JM, Skoog I, Slavin MJ, Szewieczek J, Tettamanti M, Viña J, Perls T, Sachdev PS.

BMC Neurol. 2016 Apr 21;16:52. doi: 10.1186/s12883-016-0569-4.

8.

Mortality Prediction in the Oldest Old with Five Different Equations to Estimate Glomerular Filtration Rate: The Health and Anemia Population-based Study.

Mandelli S, Riva E, Tettamanti M, Detoma P, Giacomin A, Lucca U.

PLoS One. 2015 Aug 28;10(8):e0136039. doi: 10.1371/journal.pone.0136039. eCollection 2015.

9.

Preventive study in subjects at risk of fatal familial insomnia: Innovative approach to rare diseases.

Forloni G, Tettamanti M, Lucca U, Albanese Y, Quaglio E, Chiesa R, Erbetta A, Villani F, Redaelli V, Tagliavini F, Artuso V, Roiter I.

Prion. 2015;9(2):75-9. doi: 10.1080/19336896.2015.1027857.

10.

SORL1 Gene is Associated with the Conversion from Mild Cognitive Impairment to Alzheimer's Disease.

Piscopo P, Tosto G, Belli C, Talarico G, Galimberti D, Gasparini M, Canevelli M, Poleggi A, Crestini A, Albani D, Forloni G, Lucca U, Quadri P, Tettamanti M, Fenoglio C, Scarpini E, Bruno G, Vanacore N, Confaloni A.

J Alzheimers Dis. 2015;46(3):771-6. doi: 10.3233/JAD-141551.

PMID:
25881907
11.

NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease.

Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, Lucca U, Banzi R, Pasquier F, Breuilh L, Riepe M, Kalman J, Wallin A, Borjesson A, Molloy W, Tsolaki M, Olde Rikkert M.

BMJ Open. 2014 Oct 9;4(10):e006364. doi: 10.1136/bmjopen-2014-006364. Erratum in: BMJ Open. 2015;5(9):e006364.

12.

Prevalence of dementia in the oldest old: the Monzino 80-plus population based study.

Lucca U, Tettamanti M, Logroscino G, Tiraboschi P, Landi C, Sacco L, Garrì M, Ammesso S, Bertinotti C, Biotti A, Gargantini E, Piedicorcia A, Nobili A, Pasina L, Franchi C, Djade CD, Riva E, Recchia A.

Alzheimers Dement. 2015 Mar;11(3):258-70.e3. doi: 10.1016/j.jalz.2014.05.1750. Epub 2014 Aug 20.

PMID:
25150732
13.

Doxycycline in Creutzfeldt-Jakob disease: a phase 2, randomised, double-blind, placebo-controlled trial.

Haïk S, Marcon G, Mallet A, Tettamanti M, Welaratne A, Giaccone G, Azimi S, Pietrini V, Fabreguettes JR, Imperiale D, Cesaro P, Buffa C, Aucan C, Lucca U, Peckeu L, Suardi S, Tranchant C, Zerr I, Houillier C, Redaelli V, Vespignani H, Campanella A, Sellal F, Krasnianski A, Seilhean D, Heinemann U, Sedel F, Canovi M, Gobbi M, Di Fede G, Laplanche JL, Pocchiari M, Salmona M, Forloni G, Brandel JP, Tagliavini F.

Lancet Neurol. 2014 Feb;13(2):150-8. doi: 10.1016/S1474-4422(13)70307-7. Epub 2014 Jan 8.

PMID:
24411709
14.

Association of anticholinergic burden with cognitive and functional status in a cohort of hospitalized elderly: comparison of the anticholinergic cognitive burden scale and anticholinergic risk scale: results from the REPOSI study.

Pasina L, Djade CD, Lucca U, Nobili A, Tettamanti M, Franchi C, Salerno F, Corrao S, Marengoni A, Iorio A, Marcucci M, Violi F, Mannucci PM.

Drugs Aging. 2013 Feb;30(2):103-12. doi: 10.1007/s40266-012-0044-x.

PMID:
23239364
15.

Postural stability and history of falls in cognitively able older adults: the Canton Ticino study.

Merlo A, Zemp D, Zanda E, Rocchi S, Meroni F, Tettamanti M, Recchia A, Lucca U, Quadri P.

Gait Posture. 2012 Sep;36(4):662-6. doi: 10.1016/j.gaitpost.2012.06.016. Epub 2012 Jul 24.

PMID:
22832469
16.

The SIRT2 polymorphism rs10410544 and risk of Alzheimer's disease in two Caucasian case-control cohorts.

Polito L, Kehoe PG, Davin A, Benussi L, Ghidoni R, Binetti G, Quadri P, Lucca U, Tettamanti M, Clerici F, Bagnoli S, Galimberti D, Nacmias B, Sorbi S, Guaita A, Scarpini E, Mariani C, Forloni G, Albani D.

Alzheimers Dement. 2013 Jul;9(4):392-9. doi: 10.1016/j.jalz.2012.02.003. Epub 2012 May 30.

PMID:
22651940
17.

Changes in trend of antipsychotics prescription in patients treated with cholinesterase inhibitors after warnings from Italian Medicines Agency. Results from the EPIFARM-Elderly Project.

Franchi C, Tettamanti M, Marengoni A, Bonometti F, Pasina L, Cortesi L, Fortino I, Bortolotti A, Merlino L, Lucca U, Riva E, Nobili A.

Eur Neuropsychopharmacol. 2012 Aug;22(8):569-77. doi: 10.1016/j.euroneuro.2011.12.009. Epub 2012 Jan 31.

PMID:
22297160
18.

A Population-based study of dementia in the oldest old: the Monzino 80-plus study.

Lucca U, Garrì M, Recchia A, Logroscino G, Tiraboschi P, Franceschi M, Bertinotti C, Biotti A, Gargantini E, Maragna M, Nobili A, Pasina L, Franchi C, Riva E, Tettamanti M.

BMC Neurol. 2011 May 25;11:54. doi: 10.1186/1471-2377-11-54.

19.

Interleukin-1α, interleukin-1β and tumor necrosis factor-α genetic variants and risk of dementia in the very old: evidence from the "Monzino 80-plus" prospective study.

Albani D, Tettamanti M, Batelli S, Polito L, Dusi S, Ateri E, Forloni G, Lucca U.

Age (Dordr). 2012 Apr;34(2):519-26. doi: 10.1007/s11357-011-9249-x. Epub 2011 Apr 21.

20.

Cholinesterase inhibitor use in Alzheimer's disease: the EPIFARM-Elderly Project.

Franchi C, Lucca U, Tettamanti M, Riva E, Fortino I, Bortolotti A, Merlino L, Pasina L, Nobili A.

Pharmacoepidemiol Drug Saf. 2011 May;20(5):497-505. doi: 10.1002/pds.2124.

PMID:
21432941
21.

Drug utilization and polypharmacy in an Italian elderly population: the EPIFARM-elderly project.

Nobili A, Franchi C, Pasina L, Tettamanti M, Baviera M, Monesi L, Roncaglioni C, Riva E, Lucca U, Bortolotti A, Fortino I, Merlino L.

Pharmacoepidemiol Drug Saf. 2011 May;20(5):488-96. doi: 10.1002/pds.2108. Epub 2011 Jan 24.

PMID:
21264988
22.

Co-prescription of gastroprotective agents in patients taking non-selective NSAIDs or COX-2 selective inhibitors: analysis of prescriptions.

Pasina L, Nobili A, Tettamanti M, Riva E, Lucca U, Piccinelli R, Defendi L, Perego L, Lucifora S, Bulla C.

Int J Clin Pharmacol Ther. 2010 Nov;48(11):735-43.

PMID:
20979932
23.

Prevalence, incidence and types of mild anemia in the elderly: the "Health and Anemia" population-based study.

Tettamanti M, Lucca U, Gandini F, Recchia A, Mosconi P, Apolone G, Nobili A, Tallone MV, Detoma P, Giacomin A, Clerico M, Tempia P, Savoia L, Fasolo G, Ponchio L, Della Porta MG, Riva E.

Haematologica. 2010 Nov;95(11):1849-56. doi: 10.3324/haematol.2010.023101. Epub 2010 Jun 9.

24.

The serotonin transporter promoter polymorphic region is not a risk factor for Alzheimer's disease related behavioral disturbances.

Albani D, Prato F, Tettamanti M, Lovati C, Galimberti D, Restelli I, Mariani C, Quadri PL, Scarpini E, Lucca U, Forloni G.

J Alzheimers Dis. 2009;18(1):125-30. doi: 10.3233/JAD-2009-1129.

PMID:
19625753
25.

Potentially severe drug interactions in elderly outpatients: results of an observational study of an administrative prescription database.

Nobili A, Pasina L, Tettamanti M, Lucca U, Riva E, Marzona I, Monesi L, Cucchiani R, Bortolotti A, Fortino I, Merlino L, Walter Locatelli G, Giuliani G.

J Clin Pharm Ther. 2009 Aug;34(4):377-86. doi: 10.1111/j.1365-2710.2009.01021.x.

PMID:
19583670
26.

Use and misuse of antipsychotic drugs in patients with dementia in Alzheimer special care units.

Nobili A, Pasina L, Trevisan S, Riva E, Lucca U, Tettamanti M, Matucci M, Tarantola M.

Int Clin Psychopharmacol. 2009 Mar;24(2):97-104.

PMID:
21456106
27.

Association of mild anemia with hospitalization and mortality in the elderly: the Health and Anemia population-based study.

Riva E, Tettamanti M, Mosconi P, Apolone G, Gandini F, Nobili A, Tallone MV, Detoma P, Giacomin A, Clerico M, Tempia P, Guala A, Fasolo G, Lucca U.

Haematologica. 2009 Jan;94(1):22-8. doi: 10.3324/haematol.13449. Epub 2008 Nov 10.

28.

Alzheimer special care units compared with traditional nursing home for dementia care: are there differences at admission and in clinical outcomes?

Nobili A, Piana I, Balossi L, Pasina L, Matucci M, Tarantola M, Trevisan S, Riva E, Lucca U, Tettamanti M.

Alzheimer Dis Assoc Disord. 2008 Oct-Dec;22(4):352-61. doi: 10.1097/WAD.0b013e31818207d0.

PMID:
18978601
29.

The Italian version of Consortium to Establish a Registry of Alzheimer's Disease (CERAD).

Lucca U, Tettamanti M, Quadri P.

Alzheimers Dement. 2008 Jul;4(4):310. doi: 10.1016/j.jalz.2008.05.2478. No abstract available.

PMID:
18631984
30.

Association of mild anemia with cognitive, functional, mood and quality of life outcomes in the elderly: the "Health and Anemia" study.

Lucca U, Tettamanti M, Mosconi P, Apolone G, Gandini F, Nobili A, Tallone MV, Detoma P, Giacomin A, Clerico M, Tempia P, Guala A, Fasolo G, Riva E.

PLoS One. 2008 Apr 2;3(4):e1920. doi: 10.1371/journal.pone.0001920.

31.

Role of VEGF gene variability in longevity: a lesson from the Italian population.

Del Bo R, Ghezzi S, Scarlato M, Albani D, Galimberti D, Lucca U, Tettamanti M, Scarpini E, Forloni G, Bresolin N, Comi GP.

Neurobiol Aging. 2008 Dec;29(12):1917-22. Epub 2007 Jun 15.

PMID:
17574707
32.

Low folate and the risk of cognitive and functional deficits in the very old: the Monzino 80-plus study.

Tettamanti M, Garrì MT, Nobili A, Riva E, Lucca U.

J Am Coll Nutr. 2006 Dec;25(6):502-8.

PMID:
17229897
33.

Homocysteine lowering and cognitive performance.

Lucca U, Tettamanti M, Quadri P.

N Engl J Med. 2006 Sep 28;355(13):1390; author reply 1391. No abstract available.

PMID:
17005963
34.

Cholinesterase inhibitor use and age in the general population.

Lucca U, Nobili A, Riva E, Tettamanti M.

Arch Neurol. 2006 Jan;63(1):154-5. No abstract available.

PMID:
16401754
35.

Homocysteine and B vitamins in mild cognitive impairment and dementia.

Quadri P, Fragiacomo C, Pezzati R, Zanda E, Tettamanti M, Lucca U.

Clin Chem Lab Med. 2005;43(10):1096-100.

PMID:
16197304
36.

The effect of a structured intervention on caregivers of patients with dementia and problem behaviors: a randomized controlled pilot study.

Nobili A, Riva E, Tettamanti M, Lucca U, Liscio M, Petrucci B, Porro GS.

Alzheimer Dis Assoc Disord. 2004 Apr-Jun;18(2):75-82.

PMID:
15249851
37.

Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia.

Quadri P, Fragiacomo C, Pezzati R, Zanda E, Forloni G, Tettamanti M, Lucca U.

Am J Clin Nutr. 2004 Jul;80(1):114-22.

PMID:
15213037
38.

Tumor necrosis factor alpha polymorphism C-850T is not associated with Alzheimer's disease and vascular dementia in an Italian population.

Terreni L, Fogliarino S, Quadri P, Ruggieri RM, Piccoli F, Tettamanti M, Lucca U, Forloni G.

Neurosci Lett. 2003 Jun 26;344(2):135-7.

PMID:
12782345
39.

Peripheral biomarkers of oxidative damage in Alzheimer's disease.

Chiabrando C, Fanelli R, Lucca U.

Ann Neurol. 2003 Mar;53(3):419-20; author reply 420. No abstract available.

PMID:
12601718
40.

Peripheral inflammatory response in Alzheimer's disease and multiinfarct dementia.

De Luigi A, Pizzimenti S, Quadri P, Lucca U, Tettamanti M, Fragiacomo C, De Simoni MG.

Neurobiol Dis. 2002 Nov;11(2):308-14.

PMID:
12505423
41.

Inflammatory markers in Alzheimer's disease and multi-infarct dementia.

De Luigi A, Fragiacomo C, Lucca U, Quadri P, Tettamanti M, Grazia De Simoni M.

Mech Ageing Dev. 2001 Nov;122(16):1985-95.

PMID:
11589916
42.

Apolipoprotein E and intronic polymorphism of presenilin 1 and alpha-1-antichymotrypsin in Alzheimer's disease and vascular dementia.

Rodriguez Martin T, Calella AM, Silva S, Munna E, Modena P, Chiesa R, Terrevazzi S, Ruggieri RM, Palermo R, Piccoli F, Confalonieri R, Tiraboschi P, Fragiacomo C, Quadri P, Lucca U, Forloni G.

Dement Geriatr Cogn Disord. 2000 Sep-Oct;11(5):239-44.

PMID:
10940674
43.

Efficacy and safety of eptastigmine for the treatment of patients with Alzheimer's disease.

Imbimbo BP, Martelli P, Troetel WM, Lucchelli F, Lucca U, Thal LJ.

Neurology. 1999 Mar 10;52(4):700-8.

PMID:
10078713
44.

A 25-week placebo-controlled study of eptastigmine in patients with Alzheimer disease.

Imbimbo BP, Lucca U, Lucchelli F, Alberoni M, Thal LJ.

Alzheimer Dis Assoc Disord. 1998 Dec;12(4):313-22.

PMID:
9876959
45.

Objective psychometric tests in clinical trials of dementia drugs. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines.

Ferris SH, Lucca U, Mohs R, Dubois B, Wesnes K, Erzigkeit H, Geldmacher D, Bodick N.

Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:34-8. No abstract available.

PMID:
9305514
46.

Clinical global measures of dementia. Position paper from the International Working Group on Harmonization of Dementia Drug Guidelines.

Reisberg B, Schneider L, Doody R, Anand R, Feldman H, Haraguchi H, Kumar R, Lucca U, Mangone CA, Mohr E, Morris JC, Rogers S, Sawada T.

Alzheimer Dis Assoc Disord. 1997;11 Suppl 3:8-18.

PMID:
9305508
47.

Pharmacokinetics and Safety of a Potential Antidementia Compound, CL 275,838, after Multiple Oral Doses in Patients with Dementia of Alzheimer Type or Vascular Dementia.

Caccia S, Confalonieri S, Guiso G, Lucca U, Tettamanti M, Tiraboschi P, Spagnoli A.

Am J Ther. 1995 Jan;2(1):61-67.

PMID:
11850650
48.

Nonsteroidal antiinflammatory drug use in Alzheimer's disease.

Lucca U, Tettamanti M, Forloni G, Spagnoli A.

Biol Psychiatry. 1994 Dec 15;36(12):854-6. No abstract available.

PMID:
7893851
49.

Multiple-dose pharmacokinetics and safety of a potential memory-enhancing compound, CL 275,838, in healthy male volunteers.

Caccia S, Confalonieri S, Guiso G, Lucca U, Parma E, Guido M, Tettamanti M, Tiraboschi P, Spagnoli A.

J Clin Pharmacol. 1994 Jul;34(7):748-53.

PMID:
7929869
50.

Single-dose safety and pharmacokinetics of a potential cognition-enhancing compound, CL 275,838, in healthy volunteers.

Caccia S, Confalonieri S, Guiso G, Lucca U, Parma E, Guido M, Tettamanti M, Tiraboschi P, Spagnoli A.

J Clin Pharmacol. 1993 Sep;33(9):845-50.

PMID:
8227482

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