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MECHANISMS IN ENDOCRINOLOGY: Bone Marrow Adiposity and bone, a bad romance?

Rharass T, Lucas S.

Eur J Endocrinol. 2018 Jul 4. pii: EJE-18-0182. doi: 10.1530/EJE-18-0182. [Epub ahead of print]


Group 2 Innate Lymphoid Cells Attenuate Inflammatory Arthritis and Protect from Bone Destruction in Mice.

Omata Y, Frech M, Primbs T, Lucas S, Andreev D, Scholtysek C, Sarter K, Kindermann M, Yeremenko N, Baeten DL, Andreas N, Kamradt T, Bozec A, Ramming A, Krönke G, Wirtz S, Schett G, Zaiss MM.

Cell Rep. 2018 Jul 3;24(1):169-180. doi: 10.1016/j.celrep.2018.06.005.


Proton irradiation orchestrates macrophage reprogramming through NFκB signaling.

Genard G, Wera AC, Huart C, Le Calve B, Penninckx S, Fattaccioli A, Tabarrant T, Demazy C, Ninane N, Heuskin AC, Lucas S, Michiels C.

Cell Death Dis. 2018 Jun 27;9(7):728. doi: 10.1038/s41419-018-0757-9.


Rare, potentially pathogenic variants in 21 keratoconus candidate genes are not enriched in cases in a large Australian cohort of European descent.

Lucas SEM, Zhou T, Blackburn NB, Mills RA, Ellis J, Leo P, Souzeau E, Ridge B, Charlesworth JC, Lindsay R, Craig JE, Burdon KP.

PLoS One. 2018 Jun 20;13(6):e0199178. doi: 10.1371/journal.pone.0199178. eCollection 2018.


CRISPR/Cas9 in plants: at play in the genome and at work for crop improvement.

Hussain B, Lucas SJ, Budak H.

Brief Funct Genomics. 2018 Apr 17. doi: 10.1093/bfgp/ely016. [Epub ahead of print]


Cerebral oxygenation in traumatic brain injury; Can a non-invasive frequency domain near-infrared spectroscopy device detect changes in brain tissue oxygen tension as well as the established invasive monitor?

Davies DJ, Clancy M, Dehghani H, Lucas SJE, Forcione M, Yakoub KM, Belli A.

J Neurotrauma. 2018 Jun 7. doi: 10.1089/neu.2018.5667. [Epub ahead of print]


Shining a Light on Awareness: A Review of Functional Near-Infrared Spectroscopy for Prolonged Disorders of Consciousness.

Rupawala M, Dehghani H, Lucas SJE, Tino P, Cruse D.

Front Neurol. 2018 May 22;9:350. doi: 10.3389/fneur.2018.00350. eCollection 2018. Review.


Trends of testing for and diagnosis of α1-antitrypsin deficiency in the UK: more testing is needed.

Soriano JB, Lucas SJ, Jones R, Miravitlles M, Carter V, Small I, Price D, Mahadeva R; Respiratory Effectiveness Group.

Eur Respir J. 2018 Jul 4;52(1). pii: 1800360. doi: 10.1183/13993003.00360-2018. Print 2018 Jul.


Alkene Oxyamination Using Malonoyl Peroxides: Preparation of Pyrrolidines and Isoxazolidines.

Alamillo-Ferrer C, Curle JM, Davidson SC, Lucas SCC, Atkinson SJ, Campbell M, Kennedy AR, Tomkinson NCO.

J Org Chem. 2018 Jun 15;83(12):6728-6740. doi: 10.1021/acs.joc.8b00392. Epub 2018 May 29.


Tetrapod tracks in Permo-Triassic eolian beds of southern Brazil (Paraná Basin).

Francischini H, Dentzien-Dias P, Lucas SG, Schultz CL.

PeerJ. 2018 May 18;6:e4764. doi: 10.7717/peerj.4764. eCollection 2018.


Identification of novel mutations causing pediatric cataract in Bhutan, Cambodia, and Sri Lanka.

Javadiyan S, Lucas SEM, Wangmo D, Ngy M, Edussuriya K, Craig JE, Rudkin A, Casson R, Selva D, Sharma S, Lower KM, Meucke J, Burdon KP.

Mol Genet Genomic Med. 2018 May 16. doi: 10.1002/mgg3.406. [Epub ahead of print]


Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases.

Iglesias AI, Mishra A, Vitart V, Bykhovskaya Y, Höhn R, Springelkamp H, Cuellar-Partida G, Gharahkhani P, Bailey JNC, Willoughby CE, Li X, Yazar S, Nag A, Khawaja AP, Polašek O, Siscovick D, Mitchell P, Tham YC, Haines JL, Kearns LS, Hayward C, Shi Y, van Leeuwen EM, Taylor KD; Blue Mountains Eye Study—GWAS group, Bonnemaijer P, Rotter JI, Martin NG, Zeller T, Mills RA, Staffieri SE, Jonas JB, Schmidtmann I, Boutin T, Kang JH, Lucas SEM, Wong TY, Beutel ME, Wilson JF; NEIGHBORHOOD Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Uitterlinden AG, Vithana EN, Foster PJ, Hysi PG, Hewitt AW, Khor CC, Pasquale LR, Montgomery GW, Klaver CCW, Aung T, Pfeiffer N, Mackey DA, Hammond CJ, Cheng CY, Craig JE, Rabinowitz YS, Wiggs JL, Burdon KP, van Duijn CM, MacGregor S.

Nat Commun. 2018 May 14;9(1):1864. doi: 10.1038/s41467-018-03646-6.


Posttraumatic Headache: Classification by Symptom-Based Clinical Profiles.

Lucas S, Ahn AH.

Headache. 2018 Jun;58(6):873-882. doi: 10.1111/head.13311. Epub 2018 May 8.


Higher physical fitness levels are associated with less language decline in healthy ageing.

Segaert K, Lucas SJE, Burley CV, Segaert P, Milner AE, Ryan M, Wheeldon L.

Sci Rep. 2018 Apr 30;8(1):6715. doi: 10.1038/s41598-018-24972-1.


Amoxicillin Quality and Selling Practices in Urban Pharmacies and Drug Stores of Blantyre, Malawi.

Chikowe I, Bliese SL, Lucas S, Lieberman M.

Am J Trop Med Hyg. 2018 Jul;99(1):233-238. doi: 10.4269/ajtmh.18-0003. Epub 2018 Apr 19.


Arsenic association with circulating oxidized low-density lipoprotein in a Native American community.

Harmon ME, Lewis J, Miller C, Hoover J, Ali AS, Shuey C, Cajero M, Lucas S, Pacheco B, Erdei E, Ramone S, Nez T, Campen MJ, Gonzales M.

J Toxicol Environ Health A. 2018;81(13):535-548. doi: 10.1080/15287394.2018.1443860. Epub 2018 Apr 11.


Complementary and alternative medicine utilisation for the management of acute respiratory tract infection in children: A systematic review.

Lucas S, Leach M, Kumar S.

Complement Ther Med. 2018 Apr;37:158-166. doi: 10.1016/j.ctim.2018.03.001. Epub 2018 Mar 3. Review.


Availability of Dental Prosthesis Procedures in Brazilian Primary Health Care.

Cunha MAGM, Matta-Machado ATG, Lucas SD, Abreu MHNG.

Biomed Res Int. 2018 Feb 11;2018:4536707. doi: 10.1155/2018/4536707. eCollection 2018.


Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection.

Johnson JS, Lucas SY, Amon LM, Skelton S, Nazitto R, Carbonetti S, Sather DN, Littman DR, Aderem A.

Cell Host Microbe. 2018 Mar 14;23(3):366-381.e9. doi: 10.1016/j.chom.2018.01.012.


Childhood death rates declined in Sweden from 2000 to 2014 but deaths from external causes were not always investigated.

Otterman G, Lahne K, Arkema EV, Lucas S, Janson S, Hellström-Westas L.

Acta Paediatr. 2018 Mar 8. doi: 10.1111/apa.14309. [Epub ahead of print]


Comment: On ignoring the literature and relevant tests in evaluating effectively maintained inequality.

Lucas SR.

Soc Sci Res. 2018 Mar;71:1-5. doi: 10.1016/j.ssresearch.2017.08.012. Epub 2017 Aug 26. No abstract available.


Impact of the Spinal Instability Neoplastic Score on Surgical Referral Patterns and Outcomes.

Dosani M, Lucas S, Wong J, Weir L, Lomas S, Cumayas C, Fisher C, Tyldesley S.

Curr Oncol. 2018 Feb;25(1):53-58. doi: 10.3747/co.25.3835. Epub 2018 Feb 28.


Filling process of the Child Health Record in health care services of Belo Horizonte, Minas Gerais, Brazil.

Amorim LP, Senna MIB, Gomes VE, Amaral JHLD, Vasconcelos M, Silva AGD, Lucas SD, Ferreira RC.

Epidemiol Serv Saude. 2018;27(1):e201701116. doi: 10.5123/s1679-49742018000100016. Epub 2018 Feb 15. English, Portuguese.


Glucose and lactate as metabolic constraints on presynaptic transmission at an excitatory synapse.

Lucas SJ, Michel CB, Marra V, Smalley JL, Hennig MH, Graham BP, Forsythe ID.

J Physiol. 2018 May 1;596(9):1699-1721. doi: 10.1113/JP275107. Epub 2018 Mar 26.


Prevalence and Clinical Significance of Anti-DFS70 in Antinuclear Antibody (ANA)-positive Patients Undergoing Routine ANA Testing in a New Zealand Public Hospital.

Lucas S, Chang WL, Merien F.

J Rheumatol. 2018 Feb;45(2):289-291. doi: 10.3899/jrheum.170849. No abstract available.


Starch nanocapsules containing a novel neutrophil elastase inhibitor with improved pharmaceutical performance.

Marto J, Ruivo E, Lucas SD, Gonçalves LM, Simões S, Gouveia LF, Felix R, Moreira R, Ribeiro HM, Almeida AJ.

Eur J Pharm Biopharm. 2018 Jun;127:1-11. doi: 10.1016/j.ejpb.2018.01.011. Epub 2018 Feb 1.


Contamination of estuaries from failing septic tank systems: difficulties in scaling up from monitored individual systems to cumulative impact.

Geary P, Lucas S.

Environ Sci Pollut Res Int. 2018 Feb 3. doi: 10.1007/s11356-018-1364-0. [Epub ahead of print]


The TEACHH model to predict life expectancy in patients presenting for palliative spine radiotherapy: external validation and comparison with alternate models.

Dosani M, Tyldesley S, Bakos B, Hamm J, Kong T, Lucas S, Wong J, Liu M, Hamilton S.

Support Care Cancer. 2018 Jul;26(7):2217-2227. doi: 10.1007/s00520-018-4064-x. Epub 2018 Feb 1.


Increasing cerebral blood flow reduces the severity of central sleep apnea at high altitude.

Burgess KR, Lucas SJE, Burgess KME, Sprecher KE, Donnelly J, Basnet AS, Tymko MM, Day T, Smith K, Lewis N, Ainslie PN.

J Appl Physiol (1985). 2018 May 1;124(5):1341-1348. doi: 10.1152/japplphysiol.00799.2017. Epub 2018 Feb 1.


Acetazolamide reduces exercise capacity following a 5-day ascent to 4559 m in a randomised study.

Bradwell AR, Ashdown K, Rue C, Delamere J, Thomas OD, Lucas SJE, Wright AD, Harris SJ, Myers SD; Birmingham Medical Research Expeditionary Society.

BMJ Open Sport Exerc Med. 2018 Jan 23;4(1):e000302. doi: 10.1136/bmjsem-2017-000302. eCollection 2018.


Aging Exacerbates Neuroinflammatory Outcomes Induced by Acute Ozone Exposure.

Tyler CR, Noor S, Young TL, Rivero V, Sanchez B, Lucas S, Caldwell KK, Milligan ED, Campen MJ.

Toxicol Sci. 2018 May 1;163(1):123-139. doi: 10.1093/toxsci/kfy014.


Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss.

Lucas S, Omata Y, Hofmann J, Böttcher M, Iljazovic A, Sarter K, Albrecht O, Schulz O, Krishnacoumar B, Krönke G, Herrmann M, Mougiakakos D, Strowig T, Schett G, Zaiss MM.

Nat Commun. 2018 Jan 4;9(1):55. doi: 10.1038/s41467-017-02490-4.


A pilot study to assess the effect of acute exercise on brain glutathione.

Rai S, Chowdhury A, Reniers RLEP, Wood SJ, Lucas SJE, Aldred S.

Free Radic Res. 2018 Jan;52(1):57-69. doi: 10.1080/10715762.2017.1411594. Epub 2017 Dec 13.


Rare, Potentially Pathogenic Variants in ZNF469 Are Not Enriched in Keratoconus in a Large Australian Cohort of European Descent.

Lucas SEM, Zhou T, Blackburn NB, Mills RA, Ellis J, Leo P, Souzeau E, Ridge B, Charlesworth JC, Brown MA, Lindsay R, Craig JE, Burdon KP.

Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6248-6256. doi: 10.1167/iovs.17-22417.


Assessing Transcendental Experiences vs Mental Illnesses.

Lucas S.

J Pastoral Care Counsel. 2017 Dec;71(4):267-273. doi: 10.1177/1542305017737780.


Regulatory T cells control toxicity in a humanized model of IL-2 therapy.

Li Y, Strick-Marchand H, Lim AI, Ren J, Masse-Ranson G, Dan Li, Jouvion G, Rogge L, Lucas S, Bin Li, Di Santo JP.

Nat Commun. 2017 Nov 24;8(1):1762. doi: 10.1038/s41467-017-01570-9.


Fast, asymmetric and nonhomogeneous clearance of SiC nanoaerosol assessed by micro-particle-induced x-ray emission.

Lozano O, Colaux JL, Laloy J, Alpan L, Dogné JM, Lucas S.

Nanomedicine (Lond). 2018 Jan;13(2):145-155. doi: 10.2217/nnm-2017-0245. Epub 2017 Nov 27.


Mapping QTLs conferring salt tolerance and micronutrient concentrations at seedling stagein wheat.

Hussain B, Lucas SJ, Ozturk L, Budak H.

Sci Rep. 2017 Nov 15;7(1):15662. doi: 10.1038/s41598-017-15726-6.


Problems and Progress regarding Sex Bias and Omission in Neuroscience Research.

Will TR, Proaño SB, Thomas AM, Kunz LM, Thompson KC, Ginnari LA, Jones CH, Lucas SC, Reavis EM, Dorris DM, Meitzen J.

eNeuro. 2017 Nov 9;4(6). pii: ENEURO.0278-17.2017. doi: 10.1523/ENEURO.0278-17.2017. eCollection 2017 Nov-Dec.


Diminished dynamic cerebral autoregulatory capacity with forced oscillations in mean arterial pressure with elevated cardiorespiratory fitness.

Labrecque L, Rahimaly K, Imhoff S, Paquette M, Le Blanc O, Malenfant S, Lucas SJE, Bailey DM, Smirl JD, Brassard P.

Physiol Rep. 2017 Nov;5(21). pii: e13486. doi: 10.14814/phy2.13486.


Blocking immunosuppression by human Tregs in vivo with antibodies targeting integrin αVβ8.

Stockis J, Liénart S, Colau D, Collignon A, Nishimura SL, Sheppard D, Coulie PG, Lucas S.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10161-E10168. doi: 10.1073/pnas.1710680114. Epub 2017 Nov 6.


Knowledge and Attitudes About Breast Cancer in Limpopo, South Africa.

Trupe LA, Rositch A, Dickerson L, Lucas S, Harvey SC.

J Glob Oncol. 2017 Feb 8;3(5):509-514. doi: 10.1200/JGO.2016.008102. eCollection 2017 Oct.


Pilot Educational Intervention and Feasibility Assessment of Breast Ultrasound in Rural South Africa.

Dickerson LK, Rositch AF, Lucas S, Harvey SC.

J Glob Oncol. 2017 Mar 27;3(5):502-508. doi: 10.1200/JGO.2016.008086. eCollection 2017 Oct.


Heat and Dehydration Additively Enhance Cardiovascular Outcomes following Orthostatically-Stressful Calisthenics Exercise.

Akerman AP, Lucas SJE, Katare R, Cotter JD.

Front Physiol. 2017 Oct 9;8:756. doi: 10.3389/fphys.2017.00756. eCollection 2017.


Ascorbic acid alters cell fate commitment of human neural progenitors in a WNT/β-catenin/ROS signaling dependent manner.

Rharass T, Lantow M, Gbankoto A, Weiss DG, Panáková D, Lucas S.

J Biomed Sci. 2017 Oct 16;24(1):78. doi: 10.1186/s12929-017-0385-1.


Loss of ABHD5 promotes the aggressiveness of prostate cancer cells.

Chen G, Zhou G, Aras S, He Z, Lucas S, Podgorski I, Skar W, Granneman JG, Wang J.

Sci Rep. 2017 Oct 12;7(1):13021. doi: 10.1038/s41598-017-13398-w.


The Role of Human Immunodeficiency Virus-Associated Vasculopathy in the Etiology of Stroke.

Benjamin LA, Allain TJ, Mzinganjira H, Connor MD, Smith C, Lucas S, Joekes E, Kampondeni S, Chetcuti K, Turnbull I, Hopkins M, Kamiza S, Corbett EL, Heyderman RS, Solomon T.

J Infect Dis. 2017 Sep 1;216(5):545-553. doi: 10.1093/infdis/jix340.


Chemically Induced Degradation of the Oncogenic Transcription Factor BCL6.

Kerres N, Steurer S, Schlager S, Bader G, Berger H, Caligiuri M, Dank C, Engen JR, Ettmayer P, Fischerauer B, Flotzinger G, Gerlach D, Gerstberger T, Gmaschitz T, Greb P, Han B, Heyes E, Iacob RE, Kessler D, Kölle H, Lamarre L, Lancia DR, Lucas S, Mayer M, Mayr K, Mischerikow N, Mück K, Peinsipp C, Petermann O, Reiser U, Rudolph D, Rumpel K, Salomon C, Scharn D, Schnitzer R, Schrenk A, Schweifer N, Thompson D, Traxler E, Varecka R, Voss T, Weiss-Puxbaum A, Winkler S, Zheng X, Zoephel A, Kraut N, McConnell D, Pearson M, Koegl M.

Cell Rep. 2017 Sep 19;20(12):2860-2875. doi: 10.1016/j.celrep.2017.08.081.


Periplasmic Binding Protein Dimer Has a Second Allosteric Event Tied to Ligand Binding.

Li L, Ghimire-Rijal S, Lucas SL, Stanley CB, Wright E, Agarwal PK, Myles DA, Cuneo MJ.

Biochemistry. 2017 Oct 10;56(40):5328-5337. doi: 10.1021/acs.biochem.7b00657. Epub 2017 Sep 22.


16S rRNA gene sequencing reveals site-specific signatures of the upper and lower airways of cystic fibrosis patients.

Lucas SK, Yang R, Dunitz JM, Boyer HC, Hunter RC.

J Cyst Fibros. 2018 Mar;17(2):204-212. doi: 10.1016/j.jcf.2017.08.007. Epub 2017 Aug 18.


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