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Optimal dosing of cyclophosphamide in rhabdomyosarcoma: It's complicated.

Lucas JT Jr, Pappo AS.

Cancer. 2019 Sep 15;125(18):3107-3110. doi: 10.1002/cncr.32205. Epub 2019 Jun 7. No abstract available.


Gamma Knife Radiosurgery for Multiple Sclerosis-Associated Trigeminal Neuralgia.

Helis CA, McTyre E, Munley MT, Bourland JD, Lucas JT, Cramer CK, Tatter SB, Laxton AW, Chan MD.

Neurosurgery. 2019 Nov 1;85(5):E933-E939. doi: 10.1093/neuros/nyz182.


Association between hippocampal dose and memory in survivors of childhood or adolescent low-grade glioma: a 10-year neurocognitive longitudinal study.

Acharya S, Wu S, Ashford JM, Tinkle CL, Lucas JT, Qaddoumi I, Gajjar A, Krasin MJ, Conklin HM, Merchant TE.

Neuro Oncol. 2019 Apr 12. pii: noz068. doi: 10.1093/neuonc/noz068. [Epub ahead of print]


Desmoplastic Small Round Cell Tumor: Long-Term Complications After Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy.

Stiles ZE, Murphy AJ, Anghelescu DL, Brown CL, Davidoff AM, Dickson PV, Glazer ES, Bishop MW, Furman WL, Pappo AS, Lucas JT Jr, Deneve JL.

Ann Surg Oncol. 2019 Apr 8. doi: 10.1245/s10434-019-07339-2. [Epub ahead of print]


Automatic image processing pipeline for tracking longitudinal vessel changes in magnetic resonance angiography.

Hsu CY, Li Y, Han Y, Elijovich L, Sabin ND, Abuelem T, Torabi R, Faught A, Hua CH, Klimo P, Merchant TE, Lucas JT Jr.

J Magn Reson Imaging. 2019 Oct;50(4):1063-1074. doi: 10.1002/jmri.26699. Epub 2019 Mar 7.


Implications of Image-Defined Risk Factors and Primary-Site Response on Local Control and Radiation Treatment Delivery in the Management of High-Risk Neuroblastoma: Is There a Role for De-escalation of Adjuvant Primary-Site Radiation Therapy?

Lucas JT Jr, McCarville MB, Cooper DA, Doubrovin M, Wakefield D, Santiago T, Li Y, Li X, Krasin M, Santana V, Furman W, Davidoff AM.

Int J Radiat Oncol Biol Phys. 2019 Mar 15;103(4):869-877. doi: 10.1016/j.ijrobp.2018.11.041. Epub 2018 Nov 26.


Managing local-regional failure in children with high-risk neuroblastoma: A single institution experience.

Dove AP, Manole BA, Wakefield DV, Cross SJ, Doubrovin M, Shulkin BL, Merchant TE, Davidoff AM, Furman WL, Krasin MJ, Santana VM, Lucas JT Jr.

Pediatr Blood Cancer. 2018 Dec;65(12):e27408. doi: 10.1002/pbc.27408. Epub 2018 Sep 30.


Is there a role for salvage re-irradiation in pediatric patients with locoregional recurrent rhabdomyosarcoma? Clinical outcomes from a multi-institutional cohort.

Wakefield DV, Eaton BR, Dove APH, Hsu CY, Merchant TE, Pappo A, Davidoff AM, Esiashvili N, Krasin MJ, Lucas JT Jr.

Radiother Oncol. 2018 Dec;129(3):513-519. doi: 10.1016/j.radonc.2018.06.041. Epub 2018 Jul 14.


Prior non-irradiative focal therapies do not compromise the efficacy of delayed episcleral plaque brachytherapy in retinoblastoma.

Lucas JT, McGee R, Billups CA, Qaddoumi I, Merchant TE, Brennan RC, Wu J, Wilson MW.

Br J Ophthalmol. 2018 Jun 28. pii: bjophthalmol-2018-311923. doi: 10.1136/bjophthalmol-2018-311923. [Epub ahead of print]


Excessive Treatment Failures in Patients With Parameningeal Rhabdomyosarcoma With Reduced-dose Cyclophosphamide and Delayed Radiotherapy.

Lucas JT Jr, Pappo AS, Wu J, Indelicato DJ, Krasin MJ.

J Pediatr Hematol Oncol. 2018 Jul;40(5):387-390. doi: 10.1097/MPH.0000000000001188.


Radiomics Features Differentiate Between Normal and Tumoral High-Fdg Uptake.

Hsu CY, Doubrovin M, Hua CH, Mohammed O, Shulkin BL, Kaste S, Federico S, Metzger M, Krasin M, Tinkle C, Merchant TE, Lucas JT Jr.

Sci Rep. 2018 Mar 2;8(1):3913. doi: 10.1038/s41598-018-22319-4.


Factors influencing risk-based care of the childhood cancer survivor in the 21st century.

Dixon SB, Bjornard KL, Alberts NM, Armstrong GT, Brinkman TM, Chemaitilly W, Ehrhardt MJ, Fernandez-Pineda I, Force LM, Gibson TM, Green DM, Howell CR, Kaste SC, Kirchhoff AC, Klosky JL, Krull KR, Lucas JT Jr, Mulrooney DA, Ness KK, Wilson CL, Yasui Y, Robison LL, Hudson MM.

CA Cancer J Clin. 2018 Mar;68(2):133-152. doi: 10.3322/caac.21445. Epub 2018 Jan 29. Review.


HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.

Wills S, Hwang KK, Liu P, Dennison SM, Tay MZ, Shen X, Pollara J, Lucas JT, Parks R, Rerks-Ngarm S, Pitisuttithum P, Nitayapan S, Kaewkungwal J, Thomas R, Kim JH, Michael NL, Robb ML, McRaven M, Montefiori DC, Hope TJ, Liao HX, Moody MA, Ferrari G, Haynes BF, Alam SM, Bonsignori M, Tomaras GD.

J Virol. 2018 Mar 14;92(7). pii: e01552-17. doi: 10.1128/JVI.01552-17. Print 2018 Apr 1.


Prognostic Relevance of Treatment Failure Patterns in Pediatric High-Grade Glioma: Is There a Role for a Revised Failure Classification System?

Lucas JT Jr, Cooper DA, Hwang S, Tinkle C, Li X, Li Y, Orr B, Merchant TE, Broniscer A.

Int J Radiat Oncol Biol Phys. 2017 Oct 1;99(2):450-458. doi: 10.1016/j.ijrobp.2017.04.039. Epub 2017 May 4.


Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram.

Ayala-Peacock DN, Attia A, Braunstein SE, Ahluwalia MS, Hepel J, Chung C, Contessa J, McTyre E, Peiffer AM, Lucas JT Jr, Isom S, Pajewski NM, Kotecha R, Stavas MJ, Page BR, Kleinberg L, Shen C, Taylor RB, Onyeuku NE, Hyde AT, Gorovets D, Chao ST, Corso C, Ruiz J, Watabe K, Tatter SB, Zadeh G, Chiang VLS, Fiveash JB, Chan MD.

J Neurooncol. 2017 Nov;135(2):403-411. doi: 10.1007/s11060-017-2588-4. Epub 2017 Aug 21.


Quantification of Pediatric Abdominal Organ Motion With a 4-Dimensional Magnetic Resonance Imaging Method.

Uh J, Krasin MJ, Li Y, Li X, Tinkle C, Lucas JT Jr, Merchant TE, Hua C.

Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):227-237. doi: 10.1016/j.ijrobp.2017.05.026. Epub 2017 May 25.


Pseudoprogression in pediatric low-grade glioma after irradiation.

Tsang DS, Murphy ES, Lucas JT Jr, Lagiou P, Acharya S, Merchant TE.

J Neurooncol. 2017 Nov;135(2):371-379. doi: 10.1007/s11060-017-2583-9. Epub 2017 Jul 27.


Late toxicity and outcomes following radiation therapy for chest wall sarcomas in pediatric patients.

Lucas JT Jr, Fernandez-Pineda I, Tinkle CL, Bishop MW, Kaste SC, Heda R, Davidoff AM, Krasin MJ.

Pract Radiat Oncol. 2017 Nov - Dec;7(6):411-417. doi: 10.1016/j.prro.2017.04.015. Epub 2017 Apr 26.


Craniospinal irradiation for treatment of metastatic pediatric low-grade glioma.

Tsang DS, Murphy ES, Ezell SE, Lucas JT Jr, Tinkle C, Merchant TE.

J Neurooncol. 2017 Sep;134(2):317-324. doi: 10.1007/s11060-017-2525-6. Epub 2017 Jun 17.


Posttreatment DSC-MRI is Predictive of Early Treatment Failure in Children with Supratentorial High-Grade Glioma Treated with Erlotinib.

Lucas JT Jr, Knapp BJ, Uh J, Hua CH, Merchant TE, Hwang SN, Patay Z, Broniscer A.

Clin Neuroradiol. 2018 Sep;28(3):393-400. doi: 10.1007/s00062-017-0580-1. Epub 2017 Apr 5.


Outcomes for Anaplastic Glioma Treated With Radiation Therapy With or Without Concurrent Temozolomide.

McTyre E, Lucas JT, Helis C, Farris M, Soike M, Mott R, Laxton AW, Tatter SB, Lesser GJ, Strowd RE, Lo HW, Debinski W, Chan MD.

Am J Clin Oncol. 2018 Aug;41(8):813-819. doi: 10.1097/COC.0000000000000380.


Rapid and fulminant leptomeningeal spread following radiotherapy in diffuse intrinsic pontine glioma.

Tinkle CL, Orr BA, Lucas JT Jr, Klimo P, Patay Z, Baker SJ, Broniscer A, Qaddoumi I.

Pediatr Blood Cancer. 2017 Aug;64(8). doi: 10.1002/pbc.26416. Epub 2017 Jan 13.


11C-Methionine positron emission tomography delineates non-contrast enhancing tumor regions at high risk for recurrence in pediatric high-grade glioma.

Lucas JT Jr, Serrano N, Kim H, Li X, Snyder SE, Hwang S, Li Y, Hua CH, Broniscer A, Merchant TE, Shulkin BL.

J Neurooncol. 2017 Mar;132(1):163-170. doi: 10.1007/s11060-016-2354-z. Epub 2017 Jan 11.


Predictors of neurologic and nonneurologic death in patients with brain metastasis initially treated with upfront stereotactic radiosurgery without whole-brain radiation therapy.

McTyre ER, Johnson AG, Ruiz J, Isom S, Lucas JT Jr, Hinson WH, Watabe K, Laxton AW, Tatter SB, Chan MD.

Neuro Oncol. 2017 Apr 1;19(4):558-566. doi: 10.1093/neuonc/now184.


Is a Clinical Target Volume (CTV) Necessary in the Treatment of Lung Cancer in the Modern Era Combining 4-D Imaging and Image-guided Radiotherapy (IGRT)?

Kilburn JM, Lucas JT, Soike MH, Ayala-Peacock DN, Blackstock AW, Hinson WH, Munley MT, Petty WJ, Urbanic JJ.

Cureus. 2016 Jan 23;8(1):e466. doi: 10.7759/cureus.466.


Vismodegib and Physeal Closure in a Pediatric Patient.

Lucas JT Jr, Wright KD.

Pediatr Blood Cancer. 2016 Nov;63(11):2058. doi: 10.1002/pbc.25941. Epub 2016 Feb 10. No abstract available.


Image guided radiation therapy may result in improved local control in locally advanced lung cancer patients.

Kilburn JM, Soike MH, Lucas JT, Ayala-Peacock D, Blackstock W, Isom S, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.

Pract Radiat Oncol. 2016 May-Jun;6(3):e73-e80. doi: 10.1016/j.prro.2015.10.004. Epub 2015 Oct 22.


Predictors of trigeminal nerve dysfunction following stereotactic radiosurgery for trigeminal neuralgia.

Lucas JT Jr, Huang AJ, Bourland JD, Laxton AW, Tatter SB, Chan MD.

J Radiosurg SBRT. 2016;4(2):117-123.


Local control of brain metastases after stereotactic radiosurgery: the impact of whole brain radiotherapy and treatment paradigm.

Hughes RT, Black PJ, Page BR, Lucas JT Jr, Qasem SA, Watabe K, Ruiz J, Laxton AW, Tatter SB, Debinski W, Chan MD.

J Radiosurg SBRT. 2016;4(2):89-96.


Accelerated Unilateral Radiographic Huntingtonian Changes Following Neoadjuvant Chemotherapy for a Nongerminomatous Germ Cell Tumor Leading to Identification of Occult Disease in the Dorsal Striatum.

Lucas JT Jr, Zapadka M, Houseknecht K, Buckley KS, Couture DE, Brown DR.

J Pediatr Hematol Oncol. 2016 Mar;38(2):161-2. doi: 10.1097/MPH.0000000000000450.


Factors that determine local control with gamma knife radiosurgery: The role of primary histology.

Black PJ, Page BR, Lucas JT Jr, Hughes RT, Laxton AW, Tatter SB, Munley MT, Chan MD.

J Radiosurg SBRT. 2015;3(4):281-286.


Repeat Radiosurgery for Trigeminal Neuralgia.

Helis CA, Lucas JT Jr, Bourland JD, Chan MD, Tatter SB, Laxton AW.

Neurosurgery. 2015 Nov;77(5):755-61; discussion 761. doi: 10.1227/NEU.0000000000000915.


Successful Radiofrequency Ablation for Recurrent Pulmonary Hepatoblastoma.

Dunn CL, Lucas JT Jr, Clark H, McLean TW.

Pediatr Blood Cancer. 2015 Dec;62(12):2242. doi: 10.1002/pbc.25617. Epub 2015 Jun 24. No abstract available.


Impact of systemic targeted agents on the clinical outcomes of patients with brain metastases.

Johnson AG, Ruiz J, Hughes R, Page BR, Isom S, Lucas JT, McTyre ER, Houseknecht KW, Ayala-Peacock DN, Bourland DJ, Hinson WH, Laxton AW, Tatter SB, Debinski W, Watabe K, Chan MD.

Oncotarget. 2015 Aug 7;6(22):18945-55.


Competing Risk Analysis of Neurologic versus Nonneurologic Death in Patients Undergoing Radiosurgical Salvage After Whole-Brain Radiation Therapy Failure: Who Actually Dies of Their Brain Metastases?

Lucas JT Jr, Colmer HG 4th, White L, Fitzgerald N, Isom S, Bourland JD, Laxton AW, Tatter SB, Chan MD.

Int J Radiat Oncol Biol Phys. 2015 Aug 1;92(5):1008-1015. doi: 10.1016/j.ijrobp.2015.04.032. Epub 2015 Apr 23.


Reirradiation for second primary or recurrent cancers of the head and neck: Dosimetric and outcome analysis.

Garg S, Kilburn JM, Lucas JT Jr, Randolph D, Urbanic JJ, Hinson WH, Kearns WT, Porosnicu M, Greven K.

Head Neck. 2016 Apr;38 Suppl 1:E961-9. doi: 10.1002/hed.24136. Epub 2015 Aug 11.


Anaplastic ganglioglioma: a report of three cases and review of the literature.

Lucas JT Jr, Huang AJ, Mott RT, Lesser GJ, Tatter SB, Chan MD.

J Neurooncol. 2015 May;123(1):171-7. doi: 10.1007/s11060-015-1781-6. Epub 2015 Apr 11. Review.


Proton therapy for pediatric and adolescent esthesioneuroblastoma.

Lucas JT Jr, Ladra MM, MacDonald SM, Busse PM, Friedmann AM, Ebb DH, Marcus KJ, Tarbell NJ, Yock TI.

Pediatr Blood Cancer. 2015 Sep;62(9):1523-8. doi: 10.1002/pbc.25494. Epub 2015 Mar 27.


Tumor resection with carmustine wafer placement as salvage therapy after local failure of radiosurgery for brain metastasis.

Mu F, Lucas JT Jr, Watts JM, Johnson AJ, Daniel Bourland J, Laxton AW, Chan MD, Tatter SB.

J Clin Neurosci. 2015 Mar;22(3):561-5. doi: 10.1016/j.jocn.2014.08.020. Epub 2015 Jan 2.


Gamma Knife radiosurgery for meningiomas in patients with neurofibromatosis Type 2.

Liu A, Kuhn EN, Lucas JT Jr, Laxton AW, Tatter SB, Chan MD.

J Neurosurg. 2015 Mar;122(3):536-42. doi: 10.3171/2014.10.JNS132593. Epub 2015 Jan 2.


Risk factors for leptomeningeal carcinomatosis in patients with brain metastases who have previously undergone stereotactic radiosurgery.

Huang AJ, Huang KE, Page BR, Ayala-Peacock DN, Lucas JT Jr, Lesser GJ, Laxton AW, Tatter SB, Chan MD.

J Neurooncol. 2014 Oct;120(1):163-9. doi: 10.1007/s11060-014-1539-6. Epub 2014 Jul 22.


Retrospective analysis of the impact of HPV status and smoking on mucositis in patients with oropharyngeal squamous cell carcinoma treated with concurrent chemotherapy and radiotherapy.

Vatca M, Lucas JT Jr, Laudadio J, D'Agostino RB, Waltonen JD, Sullivan CA, Rouchard-Plasser R, Matsangou M, Browne JD, Greven KM, Porosnicu M.

Oral Oncol. 2014 Sep;50(9):869-76. doi: 10.1016/j.oraloncology.2014.06.010. Epub 2014 Jul 3.


Comparison of accelerated hypofractionation and stereotactic body radiotherapy for Stage 1 and node negative Stage 2 non-small cell lung cancer (NSCLC).

Lucas JT Jr, Kuremsky JG, Soike M, Hinson WW, Kearns WT, Hampton CJ, Blackstock AW, Urbanic J.

Lung Cancer. 2014 Jul;85(1):59-65. doi: 10.1016/j.lungcan.2014.04.003. Epub 2014 Apr 28.


Management of mediastinal relapse after treatment with stereotactic body radiotherapy or accelerated hypofractionated radiotherapy for stage I/II non-small-cell lung cancer.

Kilburn JM, Lester SC, Lucas JT Jr, Soike MH, Blackstock AW, Kearns WT, Hinson WH, Miller AA, Petty WJ, Munley MT, Urbanic JJ.

J Thorac Oncol. 2014 Apr;9(4):572-6. doi: 10.1097/JTO.0000000000000086.


Predictive nomogram for the durability of pain relief from gamma knife radiation surgery in the treatment of trigeminal neuralgia.

Lucas JT Jr, Nida AM, Isom S, Marshall K, Bourland JD, Laxton AW, Tatter SB, Chan MD.

Int J Radiat Oncol Biol Phys. 2014 May 1;89(1):120-6. doi: 10.1016/j.ijrobp.2014.01.023. Epub 2014 Mar 7.


A nomogram for predicting distant brain failure in patients treated with gamma knife stereotactic radiosurgery without whole brain radiotherapy.

Ayala-Peacock DN, Peiffer AM, Lucas JT, Isom S, Kuremsky JG, Urbanic JJ, Bourland JD, Laxton AW, Tatter SB, Shaw EG, Chan MD.

Neuro Oncol. 2014 Sep;16(9):1283-8. doi: 10.1093/neuonc/nou018. Epub 2014 Feb 20.


Clinical and economic outcomes of patients with brain metastases based on symptoms: an argument for routine brain screening of those treated with upfront radiosurgery.

Lester SC, Taksler GB, Kuremsky JG, Lucas JT Jr, Ayala-Peacock DN, Randolph DM 2nd, Bourland JD, Laxton AW, Tatter SB, Chan MD.

Cancer. 2014 Feb 1;120(3):433-41. doi: 10.1002/cncr.28422. Epub 2013 Oct 21.


Cavernous sinus metastases treated with gamma knifeTM stereotactic radiosurgery.

Ayer A, Page BR, Lucas JT Jr, Bourland JD, Oliver ER, Tatter SB, Ellis TL, Chan MD.

J Radiosurg SBRT. 2014;3(2):131-137.


Evaluation of the role of secretory sphingomyelinase and bioactive sphingolipids as biomarkers in hemophagocytic lymphohistiocytosis.

Jenkins RW, Clarke CJ, Lucas JT Jr, Shabbir M, Wu BX, Simbari F, Mueller J, Hannun YA, Lazarchick J, Shirai K.

Am J Hematol. 2013 Nov;88(11):E265-72. doi: 10.1002/ajh.23535. Epub 2013 Aug 30.


Predictors of survival, neurologic death, local failure, and distant failure after gamma knife radiosurgery for melanoma brain metastases.

Neal MT, Chan MD, Lucas JT Jr, Loganathan A, Dillingham C, Pan E, Stewart JH 4th, Bourland JD, Shaw EG, Tatter SB, Ellis TL.

World Neurosurg. 2014 Dec;82(6):1250-5. doi: 10.1016/j.wneu.2013.02.025. Epub 2013 Feb 10.


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